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Aliases for CCDC127 Gene

Aliases for CCDC127 Gene

  • Coiled-Coil Domain Containing 127 2 3

External Ids for CCDC127 Gene

Previous GeneCards Identifiers for CCDC127 Gene

  • GC05M000258

Summaries for CCDC127 Gene

GeneCards Summary for CCDC127 Gene

CCDC127 (Coiled-Coil Domain Containing 127) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC127 Gene

Genomics for CCDC127 Gene

Regulatory Elements for CCDC127 Gene

Genomic Location for CCDC127 Gene

Start:
196,871 bp from pter
End:
218,218 bp from pter
Size:
21,348 bases
Orientation:
Minus strand

Genomic View for CCDC127 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC127 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC127 Gene

Proteins for CCDC127 Gene

  • Protein details for CCDC127 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96BQ5-CC127_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 127
    Protein Accession:
    Q96BQ5
    Secondary Accessions:

    Protein attributes for CCDC127 Gene

    Size:
    260 amino acids
    Molecular mass:
    30834 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC127 Gene

Proteomics data for CCDC127 Gene at MOPED

Post-translational modifications for CCDC127 Gene

  • Ubiquitination at Lys160
  • Modification sites at PhosphoSitePlus

Other Protein References for CCDC127 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC127 Gene

Domains for CCDC127 Gene

Protein Domains for CCDC127 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for CCDC127 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC127: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC127 Gene

Function for CCDC127 Gene

Animal Model Products

CRISPR Products

miRNA for CCDC127 Gene

miRTarBase miRNAs that target CCDC127

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC127

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for CCDC127 Gene

Localization for CCDC127 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC127 Gene COMPARTMENTS Subcellular localization image for CCDC127 gene
Compartment Confidence
cytosol 2
nucleus 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC127 Gene

Pathways for CCDC127 Gene

SuperPathways for CCDC127 Gene

No Data Available

Interacting Proteins for CCDC127 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000296824%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: Q96BQ5-CC127_HUMAN ENSP00000296824 for CCDC127 Gene via MINT STRING I2D

Gene Ontology (GO) - Biological Process for CCDC127 Gene

None

No data available for Pathways by source for CCDC127 Gene

Transcripts for CCDC127 Gene

mRNA/cDNA for CCDC127 Gene

(108) Selected AceView cDNA sequences:
(2) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC127 Gene

Coiled-coil domain containing 127:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC127

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC127 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5
SP1: - -
SP2: -

Relevant External Links for CCDC127 Gene

GeneLoc Exon Structure for
CCDC127
ECgene alternative splicing isoforms for
CCDC127

Expression for CCDC127 Gene

mRNA expression in normal human tissues for CCDC127 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for CCDC127 Gene

SOURCE GeneReport for Unigene cluster for CCDC127 Gene Hs.294145

genes like me logo Genes that share expressions with CCDC127: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CCDC127 Gene

Orthologs for CCDC127 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC127 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC127 35
  • 99.49 (n)
  • 99.62 (a)
CCDC127 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC127 35
  • 82.04 (n)
  • 87.98 (a)
CCDC127 36
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC127 35
  • 82.46 (n)
  • 82.71 (a)
CCDC127 36
  • 70 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc127 35
  • 81.15 (n)
  • 82.69 (a)
Ccdc127 16
Ccdc127 36
  • 83 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC127 36
  • 80 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC127 36
  • 73 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc127 35
  • 80.29 (n)
  • 81.35 (a)
chicken
(Gallus gallus)
Aves CCDC127 35
  • 67.44 (n)
  • 65.12 (a)
CCDC127 36
  • 63 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC127 36
  • 64 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc127 35
  • 64.97 (n)
  • 62.11 (a)
zebrafish
(Danio rerio)
Actinopterygii ccdc127a 35
  • 57.65 (n)
  • 52.55 (a)
ccdc127a 36
  • 49 (a)
OneToMany
ccdc127b 36
  • 49 (a)
OneToMany
Species with no ortholog for CCDC127:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC127 Gene

ENSEMBL:
Gene Tree for CCDC127 (if available)
TreeFam:
Gene Tree for CCDC127 (if available)

Paralogs for CCDC127 Gene

Pseudogenes.org Pseudogenes for CCDC127 Gene

genes like me logo Genes that share paralogs with CCDC127: view

No data available for Paralogs for CCDC127 Gene

Variants for CCDC127 Gene

Sequence variations from dbSNP and Humsavar for CCDC127 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs13474 -- 204,962(-) CCTTA(C/G)CACAA utr-variant-3-prime
rs371751 -- 210,718(+) CATCA(C/G)GATGG intron-variant
rs407844 -- 210,740(+) CAGCA(A/G)TGTGA intron-variant
rs412465 -- 214,541(-) CCTTT(C/T)CCCAT intron-variant
rs822194 -- 213,313(-) CCATC(C/G)TGATG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC127 Gene

Variant ID Type Subtype PubMed ID
essv22552 CNV CNV 17122850
dgv1733e1 CNV Complex 17122850
esv2752083 CNV Gain 17911159
dgv1734e1 CNV Complex 17122850
nsv428458 CNV Loss 18775914
dgv5878n71 CNV Loss 21882294
nsv880815 CNV Loss 21882294
nsv518607 CNV Gain 19592680
nsv523382 CNV Loss 19592680
dgv5879n71 CNV Loss 21882294
nsv881455 CNV Loss 21882294
nsv10644 CNV Gain+Loss 18304495
esv2630858 CNV Deletion 19546169
esv993161 CNV Deletion 20482838
esv29543 CNV Gain+Loss 19812545
esv1005832 CNV Deletion 20482838
esv1572597 CNV Deletion 17803354
esv1179194 CNV Deletion 17803354

Relevant External Links for CCDC127 Gene

HapMap Linkage Disequilibrium report
CCDC127

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC127 Gene

Disorders for CCDC127 Gene

No disorders were found for CCDC127 Gene.

No data available for UniProtKB/Swiss-Prot for CCDC127 Gene

Publications for CCDC127 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Functional proteomics mapping of a human signaling pathway. (PMID: 15231748) Colland F. … Gauthier J.M. (Genome Res. 2004) 3
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3

Products for CCDC127 Gene

Sources for CCDC127 Gene

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