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Aliases for CCDC126 Gene

Aliases for CCDC126 Gene

  • Coiled-Coil Domain Containing 126 2 3 5

External Ids for CCDC126 Gene

Previous GeneCards Identifiers for CCDC126 Gene

  • GC07P023603
  • GC07P023522

Summaries for CCDC126 Gene

GeneCards Summary for CCDC126 Gene

CCDC126 (Coiled-Coil Domain Containing 126) is a Protein Coding gene. GO annotations related to this gene include alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC126 Gene

Genomics for CCDC126 Gene

Regulatory Elements for CCDC126 Gene

Enhancers for CCDC126 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CCDC126 on UCSC Golden Path with GeneCards custom track

Promoters for CCDC126 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CCDC126 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC126 Gene

23,597,379 bp from pter
23,644,708 bp from pter
47,330 bases
Plus strand

Genomic View for CCDC126 Gene

Genes around CCDC126 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC126 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC126 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC126 Gene

Proteins for CCDC126 Gene

  • Protein details for CCDC126 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 126
    Protein Accession:
    Secondary Accessions:
    • A8K1J6
    • Q6UWP1
    • Q75MQ6

    Protein attributes for CCDC126 Gene

    140 amino acids
    Molecular mass:
    15668 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAQ96871.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for CCDC126 Gene

Proteomics data for CCDC126 Gene at MOPED

Post-translational modifications for CCDC126 Gene

  • Glycosylation at Asn 110 and Asn 134
  • Modification sites at PhosphoSitePlus

Other Protein References for CCDC126 Gene

No data available for DME Specific Peptides for CCDC126 Gene

Domains & Families for CCDC126 Gene

Protein Domains for CCDC126 Gene


Suggested Antigen Peptide Sequences for CCDC126 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC126: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC126 Gene

Function for CCDC126 Gene

genes like me logo Genes that share phenotypes with CCDC126: view

Animal Model Products

  • Taconic Biosciences Mouse Models for CCDC126

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC126 Gene

Localization for CCDC126 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CCDC126 Gene


Subcellular locations from

Jensen Localization Image for CCDC126 Gene COMPARTMENTS Subcellular localization image for CCDC126 gene
Compartment Confidence
extracellular 5
nucleus 2
plasma membrane 2

No data available for Gene Ontology (GO) - Cellular Components for CCDC126 Gene

Pathways & Interactions for CCDC126 Gene

SuperPathways for CCDC126 Gene

No Data Available

Interacting Proteins for CCDC126 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000304355 for CCDC126 Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for CCDC126 Gene


No data available for Pathways by source and SIGNOR curated interactions for CCDC126 Gene

Drugs & Compounds for CCDC126 Gene

No Compound Related Data Available

Transcripts for CCDC126 Gene

Unigene Clusters for CCDC126 Gene

Coiled-coil domain containing 126:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC126 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8
SP1: - - -
SP2: - -
SP3: - - - - -
SP4: - -
SP6: - - - - - -
SP7: - - - -

Relevant External Links for CCDC126 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC126 Gene

mRNA expression in normal human tissues for CCDC126 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for CCDC126 Gene

This gene is overexpressed in Serum (66.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for CCDC126 Gene

SOURCE GeneReport for Unigene cluster for CCDC126 Gene Hs.232296

genes like me logo Genes that share expression patterns with CCDC126: view

Protein tissue co-expression partners for CCDC126 Gene

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CCDC126 Gene

Orthologs for CCDC126 Gene

This gene was present in the common ancestor of animals.

Orthologs for CCDC126 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC126 35
  • 90 (n)
  • 89.29 (a)
CCDC126 36
  • 89 (a)
(Canis familiaris)
Mammalia CCDC126 35
  • 92.14 (n)
  • 95.71 (a)
CCDC126 36
  • 96 (a)
(Mus musculus)
Mammalia Ccdc126 35
  • 81.67 (n)
  • 89.29 (a)
Ccdc126 16
Ccdc126 36
  • 89 (a)
(Pan troglodytes)
Mammalia CCDC126 35
  • 99.76 (n)
  • 99.29 (a)
CCDC126 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Ccdc126 35
  • 80.71 (n)
  • 88.57 (a)
(Monodelphis domestica)
Mammalia CCDC126 36
  • 76 (a)
(Ornithorhynchus anatinus)
Mammalia CCDC126 36
  • 81 (a)
(Gallus gallus)
Aves CCDC126 35
  • 76.02 (n)
  • 78.42 (a)
CCDC126 36
  • 78 (a)
(Anolis carolinensis)
Reptilia CCDC126 36
  • 76 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc126 35
  • 71.9 (n)
  • 75 (a)
(Danio rerio)
Actinopterygii ccdc126 35
  • 63.06 (n)
  • 60.83 (a)
ccdc126 36
  • 45 (a)
(Caenorhabditis elegans)
Secernentea gly-2 36
  • 4 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 2 (a)
Species with no ortholog for CCDC126:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CCDC126 Gene

Gene Tree for CCDC126 (if available)
Gene Tree for CCDC126 (if available)

Paralogs for CCDC126 Gene

(1) SIMAP similar genes for CCDC126 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with CCDC126: view

No data available for Paralogs for CCDC126 Gene

Variants for CCDC126 Gene

Sequence variations from dbSNP and Humsavar for CCDC126 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1010499 -- 23,635,461(+) ATGTC(A/G)TCTCA intron-variant
rs1056095 -- 23,611,481(+) AAAGA(G/T)ATGTT reference, missense
rs1076410 -- 23,618,540(+) TAAAt(G/T)ttttt intron-variant
rs1076412 -- 23,619,271(-) gcgcc(A/G)tggtg intron-variant
rs6952712 -- 23,625,303(+) TAAGA(A/T)TAGAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC126 Gene

Variant ID Type Subtype PubMed ID
nsv7393 OTHER Inversion 18451855
nsv887843 CNV Gain 21882294
nsv5663 CNV Insertion 18451855
esv2734130 CNV Deletion 23290073

Variation tolerance for CCDC126 Gene

Residual Variation Intolerance Score: 38.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.07; 21.79% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for CCDC126 Gene

Disorders for CCDC126 Gene

Relevant External Links for CCDC126

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CCDC126 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC126 Gene

Publications for CCDC126 Gene

  1. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. Development and application of a DNA microarray-based yeast two-hybrid system. (PMID: 23275563) Suter B. … Wanker E.E. (Nucleic Acids Res. 2013) 3
  5. Defining the membrane proteome of NK cells. (PMID: 19946888) Ghosh D. … Wilkins J.A. (J Mass Spectrom 2010) 3

Products for CCDC126 Gene

Sources for CCDC126 Gene