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Aliases for CCDC125 Gene

Aliases for CCDC125 Gene

  • Coiled-Coil Domain Containing 125 2 3
  • Kenae 3 4 6
  • Coiled-Coil Domain-Containing Protein 125 3
  • Protein Kenae 4

External Ids for CCDC125 Gene

Previous GeneCards Identifiers for CCDC125 Gene

  • GC05M068613
  • GC05M068576
  • GC05M065532

Summaries for CCDC125 Gene

GeneCards Summary for CCDC125 Gene

CCDC125 (Coiled-Coil Domain Containing 125) is a Protein Coding gene.

UniProtKB/Swiss-Prot for CCDC125 Gene

  • May be involved in the regulation of cell migration.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC125 Gene

Genomics for CCDC125 Gene

Regulatory Elements for CCDC125 Gene

Genomic Location for CCDC125 Gene

69,280,175 bp from pter
69,332,833 bp from pter
52,659 bases
Minus strand

Genomic View for CCDC125 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC125 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC125 Gene

Proteins for CCDC125 Gene

  • Protein details for CCDC125 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 125
    Protein Accession:
    Secondary Accessions:
    • Q86Z19

    Protein attributes for CCDC125 Gene

    511 amino acids
    Molecular mass:
    58629 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CCDC125 Gene


neXtProt entry for CCDC125 Gene

Proteomics data for CCDC125 Gene at MOPED

Post-translational modifications for CCDC125 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC125 Gene

Antibody Products

No data available for DME Specific Peptides for CCDC125 Gene

Domains for CCDC125 Gene

Protein Domains for CCDC125 Gene


Suggested Antigen Peptide Sequences for CCDC125 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC125: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC125 Gene

Function for CCDC125 Gene

Molecular function for CCDC125 Gene

UniProtKB/Swiss-Prot Function:
May be involved in the regulation of cell migration.

Animal Model Products

CRISPR Products

miRNA for CCDC125 Gene

miRTarBase miRNAs that target CCDC125

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC125

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC125 Gene

Localization for CCDC125 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CCDC125 Gene


Subcellular locations from

Jensen Localization Image for CCDC125 Gene COMPARTMENTS Subcellular localization image for CCDC125 gene
Compartment Confidence
cytoskeleton 4
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for CCDC125 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with CCDC125: view

Pathways for CCDC125 Gene

SuperPathways for CCDC125 Gene

No Data Available

Interacting Proteins for CCDC125 Gene

Gene Ontology (GO) - Biological Process for CCDC125 Gene


No data available for Pathways by source for CCDC125 Gene

Transcripts for CCDC125 Gene

Unigene Clusters for CCDC125 Gene

Coiled-coil domain containing 125:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC125

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC125 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12
SP1: -
SP2: -
SP4: - -

Relevant External Links for CCDC125 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC125 Gene

mRNA expression in normal human tissues for CCDC125 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for CCDC125 Gene

This gene is overexpressed in Plasma (28.7), Fetal heart (15.2), Stomach (11.4), and Breast (8.3).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for CCDC125 Gene

SOURCE GeneReport for Unigene cluster for CCDC125 Gene Hs.654850

genes like me logo Genes that share expressions with CCDC125: view

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Expression partners for CCDC125 Gene

Orthologs for CCDC125 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC125 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC125 35
  • 85.7 (n)
  • 77.36 (a)
CCDC125 36
  • 76 (a)
(Canis familiaris)
Mammalia CCDC125 35
  • 82.91 (n)
  • 74.16 (a)
CCDC125 36
  • 68 (a)
(Mus musculus)
Mammalia Ccdc125 35
  • 79.25 (n)
  • 73.29 (a)
Ccdc125 16
Ccdc125 36
  • 74 (a)
(Pan troglodytes)
Mammalia CCDC125 35
  • 99.59 (n)
  • 99.02 (a)
CCDC125 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Ccdc125 35
  • 78.35 (n)
  • 72.11 (a)
(Monodelphis domestica)
Mammalia CCDC125 36
  • 59 (a)
(Ornithorhynchus anatinus)
Mammalia CCDC125 36
  • 54 (a)
(Gallus gallus)
Aves CCDC125 35
  • 65.83 (n)
  • 57.56 (a)
CCDC125 36
  • 55 (a)
(Anolis carolinensis)
Reptilia CCDC125 36
  • 52 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc125 35
  • 62.25 (n)
  • 54.46 (a)
(Danio rerio)
Actinopterygii ccdc125 35
  • 54.42 (n)
  • 49.33 (a)
ccdc125 36
  • 39 (a)
Species with no ortholog for CCDC125:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC125 Gene

Gene Tree for CCDC125 (if available)
Gene Tree for CCDC125 (if available)

Paralogs for CCDC125 Gene

No data available for Paralogs for CCDC125 Gene

Variants for CCDC125 Gene

Sequence variations from dbSNP and Humsavar for CCDC125 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs35950289 -- 69,283,793(+) TTTTT(-/T)GAGAC intron-variant
rs35947616 -- 69,295,886(+) ACTTC(-/T)TTTTT intron-variant
rs35682673 -- 69,306,757(+) ATTAC(-/T)TTTTG intron-variant
rs35499156 -- 69,301,093(+) CTCTC(-/A/AA)AAAAA intron-variant
rs35482488 -- 69,294,479(+) TAGAG(-/T)ACGTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC125 Gene

Variant ID Type Subtype PubMed ID
nsv821643 CNV Loss 15273396

Relevant External Links for CCDC125 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC125 Gene

Disorders for CCDC125 Gene

No disorders were found for CCDC125 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for CCDC125 Gene

Publications for CCDC125 Gene

  1. Role of Kenae/CCDC125 in cell motility through the deregulation of RhoGTPase. (PMID: 19787194) Araya N. … Nakajima T. (Int. J. Mol. Med. 2009) 3 4
  2. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J. … Rubin E.M. (Nature 2004) 4
  3. A quantitative atlas of mitotic phosphorylation. (PMID: 18669648) Dephoure N. … Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008) 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for CCDC125 Gene

Sources for CCDC125 Gene

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