Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



CCDC124 Gene

protein-coding   GIFtS: 46
GCID: GC19P018043

Coiled-Coil Domain Containing 124

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Coiled-Coil Domain Containing 1241 2
Coiled-Coil Domain-Containing Protein 1242

External Ids:    HGNC: 251711   Entrez Gene: 1150982   Ensembl: ENSG000000070807   UniProtKB: Q96CT73   

Export aliases for CCDC124 gene to outside databases

Previous GC identifers: GC19P017911 GC19P017608


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for CCDC124 Gene:
CCDC124 (coiled-coil domain containing 124) is a protein-coding gene.

UniProtKB/Swiss-Prot: CC124_HUMAN, Q96CT7
Function: Required for proper progression of late cytokinetic stages




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NC_018930.2  NT_011295.12  
Regulatory elements:
   Regulatory transcription factor binding sites in the CCDC124 gene promoter:
         SEF-1 (1)   MIF-1   AP-4   YY1   Egr-4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCCDC124 promoter sequence
   Search Chromatin IP Primers for CCDC124

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CCDC124


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.11   Ensembl cytogenetic band:  19p13.11   HGNC cytogenetic band: 19p13.11

CCDC124 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCDC124 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P018043:  view genomic region     (about GC identifiers)

Start:
18,043,824 bp from pter      End:
18,054,800 bp from pter
Size:
10,977 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: CC124_HUMAN, Q96CT7 (See protein sequence)
Recommended Name: Coiled-coil domain-containing protein 124  
Size: 223 amino acids; 25835 Da
Subunit: Interacts with RASGEF1B

Explore the universe of human proteins at neXtProt for CCDC124: NX_Q96CT7

Explore proteomics data for CCDC124 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CCDC124 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001129675.1  NP_612451.1  

    ENSEMBL proteins: 
     ENSP00000408730   ENSP00000471455   ENSP00000472520  

    CCDC124 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Proteins for CCDC124
    OriGene Protein Over-expression Lysate for CCDC124
    OriGene MassSpec for CCDC124
    OriGene Custom Protein Services for CCDC124
    GenScript Custom Purified and Recombinant Proteins Services for CCDC124
    Novus Biologicals CCDC124 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CCDC124

     
    Search eBioscience for Proteins for CCDC124 

    CCDC124 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for CCDC124
    Novus Biologicals CCDC124 Antibodies
    Abcam antibodies for CCDC124
    Cloud-Clone Corp. Antibodies for CCDC124
    ThermoFisher Antibodies for CCDC124
    LSBio Antibodies in human, mouse, rat for CCDC124

    CCDC124 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CCDC124
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CCDC124
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CCDC124
    Cloud-Clone Corp. CLIAs for CCDC124
    Search eBioscience for ELISAs for CCDC124 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    2 InterPro protein domains:
     IPR010422 DUF1014
     IPR009071 HMG_box_dom

    Graphical View of Domain Structure for InterPro Entry Q96CT7

    ProtoNet protein and cluster: Q96CT7

    UniProtKB/Swiss-Prot: CC124_HUMAN, Q96CT7
    Similarity: Belongs to the CCDC124 family


    Find genes that share domains with CCDC124           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CC124_HUMAN, Q96CT7
    Function: Required for proper progression of late cytokinetic stages

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with CCDC124           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for CCDC124:
     Low eccentricity cells 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CCDC124
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CCDC124

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CCDC124
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CCDC124

    miRNA
    Products:
        
    miRTarBase miRNAs that target CCDC124:
    hsa-mir-125b-5p (MIRT045956), hsa-mir-1 (MIRT023621)

    Block miRNA regulation of human, mouse, rat CCDC124 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate CCDC124
    SwitchGear 3'UTR luciferase reporter plasmidCCDC124 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CCDC124
    Predesigned siRNA for gene silencing in human, mouse, rat CCDC124

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CCDC124

    Clone
    Products:
         
    OriGene clones in human, mouse for CCDC124 (see all 12)
    OriGene ORF clones in mouse, rat for CCDC124
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): CCDC124 (NM_138442)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCDC124
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC124

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for CCDC124
    Browse ESI BIO Cell Lines and PureStem Progenitors for CCDC124 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC124


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    CC124_HUMAN, Q96CT7: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody.
    Note=Colocalizes with gamma-tubulin at interphase, prophase, metaphase, and anaphase. Relocates from centrosome
    to midbody at telophase
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol4
    plasma membrane4
    nucleus3

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005815microtubule organizing center IEA--
    GO:0005886plasma membrane IDA--
    GO:0030496midbody IEA--

    Find genes that share ontologies with CCDC124           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CCDC124
    Interactions:

        Search GeneGlobe Interaction Network for CCDC124

    4 Interacting proteins for CCDC124 (Q96CT73) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EIF2AK2P195253I2D: score=1 
    MAPK3P273613I2D: score=1 
    PRKAA1Q131313I2D: score=1 
    STK11Q158313I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007049cell cycle IEA--
    GO:0051301cell division IEA--

    Find genes that share ontologies with CCDC124           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CCDC124 (CC124)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for CCDC124 gene (2 alternative transcripts): 
    NM_001136203.1  NM_138442.3  

    Unigene Cluster for CCDC124:

    Coiled-coil domain containing 124
    Hs.100043  [show with all ESTs]
    Unigene Representative Sequence: BM554853
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000445755(uc010xpz.2 uc002nhs.3) ENST00000602080 ENST00000597436
    ENST00000596123
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CCDC124 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate CCDC124
    SwitchGear 3'UTR luciferase reporter plasmidCCDC124 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CCDC124
    Predesigned siRNA for gene silencing in human, mouse, rat CCDC124
    Clone
    Products:
         
    OriGene clones in human, mouse for CCDC124 (see all 12)
    OriGene ORF clones in mouse, rat for CCDC124
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): CCDC124 (NM_138442)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCDC124
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC124
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CCDC124
    OriGene qSTAR qPCR primer pairs in human, mouse for CCDC124
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CCDC124
      QuantiTect SYBR Green Assays in human, mouse, rat CCDC124
      QuantiFast Probe-based Assays in human, mouse, rat CCDC124

    Additional mRNA sequence: 

    AF086307.1 BC013949.2 

    4 DOTS entries:

    DT.413681  DT.121488116  DT.86847476  DT.40307570 

    Selected AceView cDNA sequences (see all 221):

    BE047676 BM554613 BQ674818 BM915698 BE733893 BQ229154 BM714338 BU150296 
    AW004678 BU156886 BQ671436 BU626106 BE791952 BI837656 BG765309 BF195195 
    BE263563 BM998230 BM720670 CF126134 BM713745 AI374691 AA896971 BM723679 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    CCDC124 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTCTTATCAC
    CCDC124 Expression
    About this image


    CCDC124 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 9) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Ovarian Mesenchymal Stroma Cells Ovary Interstitium
             Oviduct
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    CCDC124 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CCDC124 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.100043

    UniProtKB/Swiss-Prot: CC124_HUMAN, Q96CT7
    Tissue specificity: Ubiquitously expressed

        Custom PCR Arrays for CCDC124
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for CCDC124
    OriGene qSTAR qPCR primer pairs in human, mouse for CCDC124
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CCDC124
    QuantiTect SYBR Green Assays in human, mouse, rat CCDC124
    QuantiFast Probe-based Assays in human, mouse, rat CCDC124
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC124

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CCDC124 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ccdc1241 , 5 coiled-coil domain containing 1241, 5 84.33(n)1
    90.32(a)1
      8 (34.33 cM)5
    2343881  NM_026964.31  NP_081240.11 
     708682275 
    chicken
    (Gallus gallus)
    Aves CCDC1241 coiled-coil domain containing 124 76.92(n)
    82.81(a)
      427087  XM_424681.4  XP_424681.1 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.35322 Xenopus laevis transcribed sequence with weak similarity more 78.42(n)    CD361620.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BC056579.12   -- 76.5(n)   393537  BC056579.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG60131 CG6013 56.09(n)
    45.19(a)
      42286  NM_142520.3  NP_650777.1 
    worm
    (Caenorhabditis elegans)
    Secernentea Y73E7A.11 Y73E7A.1 55.45(n)
    54.21(a)
      171725  NM_001047247.2  NP_001040712.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G162101 AT1G16210 50.23(n)
    36.15(a)
      838189  NM_101487.4  NP_563993.1 
    rice
    (Oryza sativa)
    Liliopsida Os04g05616001 Os04g0561600 55.77(n)
    43.6(a)
      4336658  NM_001060088.1  NP_001053553.1 


    ENSEMBL Gene Tree for CCDC124 (if available)
    TreeFam Gene Tree for CCDC124 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for CCDC124 (see all 306)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs104139191,2
    C,F,A--18041925(+) gaactC/Actcac 1 -- us2k17Minor allele frequency- A:0.40NA WA CSA EA 249
    rs1503783821,2
    --18041966(+) GTGCTG/TGGATT 1 -- us2k10--------
    rs1851808841,2
    --18042078(+) ATCTCA/GGCTCA 1 -- us2k10--------
    rs1899131211,2
    --18042268(+) CCTCCC/TAAAGT 1 -- us2k10--------
    rs1929812601,2
    --18042342(+) TTCACC/GCAGGC 1 -- us2k10--------
    rs360740061,2
    C,F--18042412(+) TGATTC/TTCTTG 1 -- us2k18Minor allele frequency- T:0.29NA WA EA 368
    rs560875301,2
    C,F--18042432(+) ATGAGC/GATGCC 1 -- us2k18Minor allele frequency- G:0.30NA WA CSA EA 367
    rs1154589831,2
    F--18042524(+) CAAGCG/TATCCT 1 -- us2k11Minor allele frequency- T:0.02WA 118
    rs118806851,2
    C,F,A,H--18042569(+) GCATGA/TGCCAC 1 -- us2k112Minor allele frequency- T:0.26NA WA CSA EA 380
    rs1380611001,2
    --18042581(+) GCGACA/CAGCCA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CCDC124 (18043824 - 18054800 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for CCDC124:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2232366CNV Deletion18987734
    esv2667655CNV Deletion23128226
    dgv3767n71CNV Loss21882294
    nsv470130CNV Loss18288195
    nsv911214CNV Loss21882294
    nsv911226CNV Loss21882294
    nsv911227CNV Loss21882294
    nsv833772CNV Gain+Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CCDC124
    DNA2.0 Custom Variant and Variant Library Synthesis for CCDC124

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for CCDC124 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with CCDC124)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Coiled-coil domain containing protein 124 is a novel centrosome and midbody protein that interacts with the ras-guanine nucleotide exchange factor 1B and is involved in cytokinesis. (PubMed id 23894443)1, 2, 3 Telkoparan P....Tazebay U.H. (PLoS ONE 2013)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    4. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    5. Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S.... Dorf M.E. (Immunity 2011)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    9. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    10. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 115098 HGNC: 25171 AceView: LOC115098 Ensembl:ENSG00000007080 euGenes: HUgn115098
    ECgene: CCDC124 H-InvDB: CCDC124

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for CCDC124 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for CCDC124 gene:
    Search GeneIP for patents involving CCDC124

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for CCDC124  
     OriGene qPCR primer pairs and template standards for CCDC124   OriGene Protein Over-expression Lysate for CCDC124  
     OriGene MassSpec something-or-other for CCDC124   OriGene clones in human, mouse for CCDC124  
     OriGene qSTAR qPCR primer pairs in human, mouse for CCDC124   OriGene Purified Protein for CCDC124  
     OriGene ORF clones in mouse, rat for CCDC124   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CCDC124   OriGene Custom Protein Services for CCDC124  

     
     
     Block miRNA regulation of human, mouse, rat CCDC124 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CCDC124
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CCDC124 Predesigned siRNA for gene silencing in human, mouse, rat CCDC124
     QuantiFast Probe-based Assays in human, mouse, rat CCDC124 QuantiTect SYBR Green Assays in human, mouse, rat CCDC124
     Custom PCR Arrays for CCDC124 Search Chromatin IP Primers for CCDC124
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CCDC124  Search GeneGlobe Interaction Network for CCDC124
     Regulatory tfbs in CCDC124 promoter
     GenScript Custom Purified and Recombinant Proteins Services for CCDC124 GenScript cDNA clones with any tag delivered in your preferred vector for CCDC124
     GenScript Custom Assay Services for CCDC124 GenScript Custom overexpressing Cell Line Services for CCDC124
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for CCDC124 (CC124)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     CCDC124 antibodies
     CCDC124 lysates
     Antibodies for CCDC124
     See all of Abcam's Antibodies, Kits and Proteins for CCDC124
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for CCDC124
     Antibodies for CCDC124
     ELISAs for CCDC124
     CLIAs for CCDC124



     Browse ESI BIO Cell Lines and PureStem Progenitors for CCDC124
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC124
     SwitchGear 3'UTR luciferase reporter plasmids for CCDC124
     SwitchGear Promoter luciferase reporter plasmids for CCDC124
     ThermoFisher Antibodies for CCDC124
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC124
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CCDC124
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CCDC124
     LSBio Antibodies in human, mouse, rat for CCDC124
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for CCDC124
      Search eBioscience for proteins for CCDC124
      Search eBioscience for elisas for CCDC124
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      CCDC124 gene at Home site.
    Version: 3.12.224 13 Oct 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4