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Aliases for CCDC122 Gene

Aliases for CCDC122 Gene

  • Coiled-Coil Domain Containing 122 2 3

External Ids for CCDC122 Gene

Previous GeneCards Identifiers for CCDC122 Gene

  • GC13M043309
  • GC13M044398
  • GC13M025212

Summaries for CCDC122 Gene

GeneCards Summary for CCDC122 Gene

CCDC122 (Coiled-Coil Domain Containing 122) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC122 Gene

Genomics for CCDC122 Gene

Regulatory Elements for CCDC122 Gene

Genomic Location for CCDC122 Gene

43,823,909 bp from pter
43,879,727 bp from pter
55,819 bases
Minus strand

Genomic View for CCDC122 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC122 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC122 Gene

Proteins for CCDC122 Gene

  • Protein details for CCDC122 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 122
    Protein Accession:
    Secondary Accessions:
    • B2RP70
    • B7ZMI9
    • Q96MV0

    Protein attributes for CCDC122 Gene

    273 amino acids
    Molecular mass:
    32206 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CCDC122 Gene


neXtProt entry for CCDC122 Gene

Proteomics data for CCDC122 Gene at MOPED

Post-translational modifications for CCDC122 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC122 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC122 Gene

Domains for CCDC122 Gene

Protein Domains for CCDC122 Gene


Suggested Antigen Peptide Sequences for CCDC122 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC122: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC122 Gene

Function for CCDC122 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC122 Gene

Localization for CCDC122 Gene

Subcellular locations from

Jensen Localization Image for CCDC122 Gene COMPARTMENTS Subcellular localization image for CCDC122 gene
Compartment Confidence
cytosol 3
nucleus 3
peroxisome 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC122 Gene

Pathways for CCDC122 Gene

SuperPathways for CCDC122 Gene

No Data Available

Interacting Proteins for CCDC122 Gene

Gene Ontology (GO) - Biological Process for CCDC122 Gene


No data available for Pathways by source for CCDC122 Gene

Transcripts for CCDC122 Gene

Unigene Clusters for CCDC122 Gene

Coiled-coil domain containing 122:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC122

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC122 Gene

No ASD Table

Relevant External Links for CCDC122 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC122 Gene

mRNA expression in normal human tissues for CCDC122 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for CCDC122 Gene

This gene is overexpressed in Prostate (40.4), Rectum (21.0), and Urinary Bladder (7.6).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for CCDC122 Gene

SOURCE GeneReport for Unigene cluster for CCDC122 Gene Hs.170849

genes like me logo Genes that share expressions with CCDC122: view

Expression partners for CCDC122 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CCDC122 Gene

Orthologs for CCDC122 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC122 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC122 35
  • 87.01 (n)
  • 80.88 (a)
CCDC122 36
  • 79 (a)
(Canis familiaris)
Mammalia CCDC122 35
  • 89.13 (n)
  • 82.42 (a)
CCDC122 36
  • 82 (a)
(Mus musculus)
Mammalia Ccdc122 35
  • 82.28 (n)
  • 70.26 (a)
Ccdc122 16
Ccdc122 36
  • 65 (a)
(Pan troglodytes)
Mammalia CCDC122 35
  • 97.13 (n)
  • 95.88 (a)
CCDC122 36
  • 79 (a)
(Rattus norvegicus)
Mammalia Ccdc122 35
  • 80.7 (n)
  • 68.42 (a)
(Monodelphis domestica)
Mammalia CCDC122 36
  • 66 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 64 (a)
-- 36
  • 54 (a)
-- 36
  • 59 (a)
(Gallus gallus)
Aves CCDC122 35
  • 67.06 (n)
  • 56.13 (a)
CCDC122 36
  • 52 (a)
(Anolis carolinensis)
Reptilia CCDC122 36
  • 49 (a)
Species with no ortholog for CCDC122:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC122 Gene

Gene Tree for CCDC122 (if available)
Gene Tree for CCDC122 (if available)

Paralogs for CCDC122 Gene

(17) SIMAP similar genes for CCDC122 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with CCDC122: view

No data available for Paralogs for CCDC122 Gene

Variants for CCDC122 Gene

Sequence variations from dbSNP and Humsavar for CCDC122 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
rs80146963 -- 43,855,135(+) ATCAG(G/T)CAAGA intron-variant
rs79944357 -- 43,866,684(+) GGTTT(C/T)GATGG intron-variant
rs79782223 -- 43,837,285(+) TTACT(C/T)TTGCA missense, reference
rs79697600 -- 43,868,738(+) TGATG(C/T)TTGTG missense, reference, intron-variant
rs79509039 -- 43,855,125(-) TTGCC(C/T)TGGCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC122 Gene

Variant ID Type Subtype PubMed ID
nsv832595 CNV Gain 17160897
esv273426 CNV Insertion 20981092

Relevant External Links for CCDC122 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC122 Gene

Disorders for CCDC122 Gene

(1) University of Copenhagen DISEASES for CCDC122 Gene

Relevant External Links for CCDC122

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with CCDC122: view

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships and Genatlas for CCDC122 Gene

Publications for CCDC122 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Genomewide association study of leprosy. (PMID: 20018961) Zhang F.R. … Liu J.J. (N. Engl. J. Med. 2009) 3 48
  3. NOD2 and CCDC122-LACC1 genes are associated with leprosy susceptibility in Brazilians. (PMID: 25367361) Sales-Marques C. … Pereira Latini A.C. (Hum. Genet. 2014) 3
  4. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A. … Ross M.T. (Nature 2004) 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for CCDC122 Gene

Sources for CCDC122 Gene

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