CCDC122 Gene
protein-coding GIFtS: 40
GCID: GC13M044398
|
|
coiled-coil domain containing 122
| |
Aliases
for CCDC122 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Coiled-Coil Domain Containing 1221 2 | | FLJ318461 | | Coiled-Coil Domain-Containing Protein 1222 |
Export aliases for CCDC122 gene to outside databasesPrevious GC identifers: GC13M043309 GC13M025212 |
Summaries
for CCDC122 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CCDC122 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000013.10 NC_018924.1 NT_024524.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CCDC122 gene promoter:
C/EBPbeta AML1a Nkx2-2 HSF1 (long) C/EBPalpha Ik-2 Cart-1 HSF1short
Other transcription factors
Search SABiosciences Chromatin IP Primers for CCDC122
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC122 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 13q14.11 Ensembl cytogenetic band: 13q14.11 HGNC cytogenetic band: 13q14.11CCDC122 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 13 GeneLoc Exon Structure GeneLoc location for GC13M044398: view genomic region
(about GC identifiers)
Start:
|
44,398,045 bp from pter |
End:
|
44,453,864 bp from pter |
Size:
|
55,820 bases |
Orientation:
|
minus strand |
|
Proteins
for CCDC122 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CC122_HUMAN, Q5T0U0 (See
protein sequence)Recommended Name: Coiled-coil domain-containing protein 122 Size: 273 amino acids; 32206 Da
Secondary accessions: B2RP70 B7ZMI9 Q96MV0Alternative splicing: 2 isoforms: Q5T0U0-1 Q5T0U0-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CCDC122: NX_Q5T0U0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5T0U0
CCDC122 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_659411.2
ENSEMBL proteins: ENSP00000407763 ENSP00000432874 ENSP00000281508
Human Recombinant Protein Products:
CCDC122 Antibody Products:
Assay Products for CCDC122: |
Protein
Domains /
Families
for CCDC122 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q5T0U0 |
Function
for CCDC122 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC122 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC122
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CCDC122 (NM_144974) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC122 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC122 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC122 |
|
Pathways & Interactions
for CCDC122 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CCDC122
|
Drugs & Compounds
for CCDC122 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CCDC122
Search CenterWatch for drugs/clinical trials and news about CCDC122 / CC122
|
Transcripts
for CCDC122 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CCDC122 gene: NM_144974.3 Unigene Cluster for CCDC122: Coiled-coil domain containing 122 Hs.170849 [show with all ESTs]Unigene Representative Sequence: NM_1449745 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000470137 ENST00000444614(uc010acf.3) ENST00000476570(uc010tfn.1)
ENST00000482922 ENST00000281508
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC122 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC122
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CCDC122 (NM_144974) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC122 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC122 |
Additional cDNA sequence: BC137289.1 BC137290.1 BC144570.1 BC144571.1 6 DOTS entries: DT.95255628 DT.120790815 DT.100715796 DT.402773 DT.86835824 DT.40198230 20 AceView cDNA sequences: BP334515 AW105039 AA831250 CB069203 AW451953 NM_144974 AA761347 BG212997 AI800705 AA994471 AI377779 AK056408 AI743531 BG210897 AI613080 BQ016613 BE569088 BE865617 BI054673 AW444706
GeneLoc Exon Structure
|
Expression
for CCDC122 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CCDC122 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See CCDC122 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CCDC122
SOURCE GeneReport for Unigene cluster: Hs.170849
SABiosciences Custom PCR Arrays for CCDC122
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC122
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CCDC122 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC122 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC122 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC122 |
Orthologs
for CCDC122 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for CCDC122 gene from 3/10 species (see all 10) About this table
ENSEMBL Gene Tree for CCDC122 (if available)
TreeFam Gene Tree for CCDC122 (if available) |
Paralogs
for CCDC122 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for CCDC122 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 13 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CCDC122 (44398045 - 44453864 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for CCDC122
1 CNV: 4801 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCDC122 |
|
Disorders
/ Diseases
for CCDC122 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CCDC122 for disorders About GeneDecksing
OMIM gene information: 613408
OMIM disorders: --
2  diseases for CCDC122: About MalaCardspolydactyly leprosy
1 disease from the University of Copenhagen DISEASES database for CCDC122:Leprosy Human Genome Epidemiology (HuGE) Navigator: CCDC122 (1 document)
Export disorders for CCDC122 gene to outside databases
|
Publications
for CCDC122 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CCDC122 gene integrated from 9 sources:
(articles sorted by number of sources associating them with CCDC122) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Genomewide association study of leprosy. (PubMed id 20018961)1 Zhang F.R....Liu J.J. (2009)
- Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns. (PubMed id 17672918)1 Szafranski K....Platzer M. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)2 Dunham A.... Ross M.T. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for CCDC122 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CCDC122 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CCDC122 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CCDC122 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CCDC122 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CCDC122 gene:
Search GeneIP for patents involving CCDC122
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CCDC122 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CCDC122 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CCDC122 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC122 | | | OriGene Protein Over-expression Lysate for CCDC122 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CCDC122 | | OriGene 3'-UTR Clone for CCDC122 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC122 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC122 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CCDC122 | | OriGene Custom Protein Services for CCDC122 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CCDC122 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCDC122 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC122 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCDC122 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC122 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC122 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for CCDC122 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | CCDC122 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC122 |
|  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC122 |
|
|
|
|
