Free for academic non-profit institutions. Other users need a Commercial license

Aliases for CCDC121 Gene

Aliases for CCDC121 Gene

  • Coiled-Coil Domain Containing 121 2 3

External Ids for CCDC121 Gene

Previous GeneCards Identifiers for CCDC121 Gene

  • GC02M027702
  • GC02M027849
  • GC02M027590

Summaries for CCDC121 Gene

GeneCards Summary for CCDC121 Gene

CCDC121 (Coiled-Coil Domain Containing 121) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC121 Gene

Genomics for CCDC121 Gene

Regulatory Elements for CCDC121 Gene

Genomic Location for CCDC121 Gene

27,625,638 bp from pter
27,629,031 bp from pter
3,394 bases
Minus strand

Genomic View for CCDC121 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC121 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC121 Gene

Proteins for CCDC121 Gene

  • Protein details for CCDC121 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 121
    Protein Accession:
    Secondary Accessions:
    • B3KW66
    • J3KQZ8
    • Q9H8G6

    Protein attributes for CCDC121 Gene

    278 amino acids
    Molecular mass:
    33061 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAX93200.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAB14651.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC121 Gene


neXtProt entry for CCDC121 Gene

Proteomics data for CCDC121 Gene at MOPED

Post-translational modifications for CCDC121 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC121 Gene

No data available for DME Specific Peptides for CCDC121 Gene

Domains & Families for CCDC121 Gene

Protein Domains for CCDC121 Gene


Suggested Antigen Peptide Sequences for CCDC121 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC121: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC121 Gene

Function for CCDC121 Gene

Gene Ontology (GO) - Molecular Function for CCDC121 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 21516116
genes like me logo Genes that share ontologies with CCDC121: view

Phenotypes for CCDC121 Gene

genes like me logo Genes that share phenotypes with CCDC121: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC121

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC121 Gene

Localization for CCDC121 Gene

Subcellular locations from

Jensen Localization Image for CCDC121 Gene COMPARTMENTS Subcellular localization image for CCDC121 gene
Compartment Confidence
cytoskeleton 2
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC121 Gene

Pathways & Interactions for CCDC121 Gene

SuperPathways for CCDC121 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC121 Gene


No data available for Pathways by source and SIGNOR curated interactions for CCDC121 Gene

Drugs & Compounds for CCDC121 Gene

No Compound Related Data Available

Transcripts for CCDC121 Gene

Unigene Clusters for CCDC121 Gene

Coiled-coil domain containing 121:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC121

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC121 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b · 3c
SP1: - -

Relevant External Links for CCDC121 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC121 Gene

mRNA expression in normal human tissues for CCDC121 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC121 Gene

This gene is overexpressed in Testis (x5.3).

Protein differential expression in normal tissues from HIPED for CCDC121 Gene

This gene is overexpressed in Serum (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CCDC121 Gene

SOURCE GeneReport for Unigene cluster for CCDC121 Gene Hs.21081

genes like me logo Genes that share expression patterns with CCDC121: view

Protein tissue co-expression partners for CCDC121 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for CCDC121 Gene

Orthologs for CCDC121 Gene

This gene was present in the common ancestor of mammals.

Orthologs for CCDC121 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Ccdc121 35
  • 62.27 (n)
  • 43.56 (a)
Ccdc121 16
4930548H24Rik 36
  • 26 (a)
Ccdc121 36
  • 41 (a)
Gm6583 36
  • 27 (a)
Gm6588 36
  • 26 (a)
(Pan troglodytes)
Mammalia CCDC121 35
  • 99.55 (n)
  • 98.86 (a)
CCDC121 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Ccdc121 35
  • 61.66 (n)
  • 41.53 (a)
(Canis familiaris)
Mammalia -- 36
  • 58 (a)
-- 36
  • 63 (a)
-- 36
  • 59 (a)
(Monodelphis domestica)
Mammalia CCDC121 36
  • 32 (a)
(Ornithorhynchus anatinus)
Mammalia CCDC121 36
  • 35 (a)
Species with no ortholog for CCDC121:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC121 Gene

Gene Tree for CCDC121 (if available)
Gene Tree for CCDC121 (if available)

Paralogs for CCDC121 Gene Pseudogenes for CCDC121 Gene

genes like me logo Genes that share paralogs with CCDC121: view

No data available for Paralogs for CCDC121 Gene

Variants for CCDC121 Gene

Sequence variations from dbSNP and Humsavar for CCDC121 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs3946319 -- 27,626,047(-) TGTGT(A/G)CCATA utr-variant-3-prime
rs4665384 -- 27,625,530(+) ATCCT(A/G)ATTTC downstream-variant-500B
rs4666003 -- 27,625,719(+) AAGCT(A/C)CAAGG utr-variant-3-prime
rs62138974 -- 27,625,201(+) CAAGC(C/T)CTCAC downstream-variant-500B
rs113925459 -- 27,626,045(+) CATAT(A/G)GCACA utr-variant-3-prime

Variation tolerance for CCDC121 Gene

Residual Variation Intolerance Score: 58.29% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.67; 31.98% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC121 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CCDC121 Gene

Disorders for CCDC121 Gene

Relevant External Links for CCDC121

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with CCDC121: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC121 Gene

Publications for CCDC121 Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  3. A Y2H-seq approach defines the human protein methyltransferase interactome. (PMID: 23455924) Weimann M. … Stelzl U. (Nat. Methods 2013) 67
  4. A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. (PMID: 21386085) Kraja A.T. … Borecki I.B. (Diabetes 2011) 67
  5. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H. … Vidal M. (Nat. Methods 2011) 67

Products for CCDC121 Gene

Sources for CCDC121 Gene

Back to Top