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Aliases for CCDC120 Gene

Aliases for CCDC120 Gene

  • Coiled-Coil Domain Containing 120 2 3
  • Coiled-Coil Domain-Containing Protein 120 3
  • JM11 3

External Ids for CCDC120 Gene

Previous GeneCards Identifiers for CCDC120 Gene

  • GC0XP048803
  • GC0XP048916
  • GC0XP046573

Summaries for CCDC120 Gene

Entrez Gene Summary for CCDC120 Gene

  • This gene encodes a protein that contains a coiled-coil domain. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Nov 2012]

GeneCards Summary for CCDC120 Gene

CCDC120 (Coiled-Coil Domain Containing 120) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC120 Gene

Genomics for CCDC120 Gene

Regulatory Elements for CCDC120 Gene

Genomic Location for CCDC120 Gene

Start:
49,053,432 bp from pter
End:
49,069,858 bp from pter
Size:
16,427 bases
Orientation:
Plus strand

Genomic View for CCDC120 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC120 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC120 Gene

Proteins for CCDC120 Gene

  • Protein details for CCDC120 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96HB5-CC120_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 120
    Protein Accession:
    Q96HB5
    Secondary Accessions:
    • B4DFC1
    • B4DTU2
    • F5GZU4

    Protein attributes for CCDC120 Gene

    Size:
    630 amino acids
    Molecular mass:
    67567 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CCDC120 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC120 Gene

Proteomics data for CCDC120 Gene at MOPED

Post-translational modifications for CCDC120 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CCDC120 Gene

Domains for CCDC120 Gene

Protein Domains for CCDC120 Gene

Blocks:
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CCDC120 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC120: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC120 Gene

Function for CCDC120 Gene

Gene Ontology (GO) - Molecular Function for CCDC120 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with CCDC120: view

Phenotypes for CCDC120 Gene

GenomeRNAi human phenotypes for CCDC120:
genes like me logo Genes that share phenotypes with CCDC120: view

Animal Model Products

CRISPR Products

miRNA for CCDC120 Gene

miRTarBase miRNAs that target CCDC120

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC120

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for CCDC120 Gene

Localization for CCDC120 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC120 Gene COMPARTMENTS Subcellular localization image for CCDC120 gene
Compartment Confidence
nucleus 3
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC120 Gene

Pathways for CCDC120 Gene

SuperPathways for CCDC120 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC120 Gene

None

No data available for Pathways by source for CCDC120 Gene

Transcripts for CCDC120 Gene

Unigene Clusters for CCDC120 Gene

Coiled-coil domain containing 120:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC120

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for CCDC120

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC120 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b ^ 11
SP1: - - - -
SP2: - -
SP3: -
SP4:

Relevant External Links for CCDC120 Gene

GeneLoc Exon Structure for
CCDC120
ECgene alternative splicing isoforms for
CCDC120

Expression for CCDC120 Gene

mRNA expression in normal human tissues for CCDC120 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCDC120 Gene

This gene is overexpressed in Esophagus - Mucosa (5.3) and Skin - Sun Exposed (Lower leg) (4.3).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for CCDC120 Gene

SOURCE GeneReport for Unigene cluster for CCDC120 Gene Hs.522643

genes like me logo Genes that share expressions with CCDC120: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for CCDC120 Gene

Orthologs for CCDC120 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC120 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC120 35
  • 99.7 (n)
  • 99.54 (a)
CCDC120 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC120 35
  • 89.67 (n)
  • 91.49 (a)
CCDC120 36
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC120 35
  • 91.03 (n)
  • 93.24 (a)
CCDC120 36
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc120 35
  • 85.78 (n)
  • 88.98 (a)
Ccdc120 16
Ccdc120 36
  • 90 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC120 36
  • 58 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC120 36
  • 72 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc120 35
  • 86.47 (n)
  • 89.36 (a)
lizard
(Anolis carolinensis)
Reptilia CCDC120 36
  • 49 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii ccdc120 35
  • 55.01 (n)
  • 47.56 (a)
ccdc120 36
  • 30 (a)
OneToMany
CCDC120 (1 of 2) 36
  • 32 (a)
OneToMany
Species with no ortholog for CCDC120:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC120 Gene

ENSEMBL:
Gene Tree for CCDC120 (if available)
TreeFam:
Gene Tree for CCDC120 (if available)

Paralogs for CCDC120 Gene

Selected SIMAP similar genes for CCDC120 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with CCDC120: view

No data available for Paralogs for CCDC120 Gene

Variants for CCDC120 Gene

Sequence variations from dbSNP and Humsavar for CCDC120 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs1132413 -- 49,069,601(+) ACCTC(A/G)TGATC utr-variant-3-prime
rs2293944 -- 49,064,029(+) CAAGA(A/G)GGTGG intron-variant
rs4824459 -- 49,056,720(+) AAACA(A/C)CTGTT intron-variant
rs5905718 -- 49,056,431(+) agccc(A/C)ccctg intron-variant
rs5905719 -- 49,056,500(+) cacgc(A/C)cctgt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC120 Gene

Variant ID Type Subtype PubMed ID
esv32909 CNV Gain+Loss 17666407
nsv528292 CNV Gain 19592680

Relevant External Links for CCDC120 Gene

HapMap Linkage Disequilibrium report
CCDC120
Locus Specific Mutation Databases (LSDB)
CCDC120

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC120 Gene

Disorders for CCDC120 Gene

No disorders were found for CCDC120 Gene.

No data available for UniProtKB/Swiss-Prot for CCDC120 Gene

Publications for CCDC120 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Arf6 guanine nucleotide exchange factor cytohesin-2 binds to CCDC120 and is transported along neurites to mediate neurite growth. (PMID: 25326380) Torii T. … Yamauchi J. (J. Biol. Chem. 2014) 2 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 4

Products for CCDC120 Gene

Sources for CCDC120 Gene

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