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CCDC12 Gene

protein-coding   GIFtS: 50
GCID: GC03M046939

Coiled-Coil Domain Containing 12

  Search for CCDC12
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): antisense

Quality score for the ORGUL clustered with this gene is 3

Aliases
Coiled-Coil Domain Containing 121 2
Coiled-Coil Domain-Containing Protein 122
CCDC1235
CEP1235
CEP895
FLJ146405

External Ids:    HGNC: 283321   Entrez Gene: 1519032   Ensembl: ENSG000001607997   OMIM: 6154705   UniProtKB: Q8WUD43   
ORGUL members:         

Export aliases for CCDC12 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CCDC12 Gene:
CCDC12 (coiled-coil domain containing 12) is a protein-coding gene.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the CCDC12 gene promoter:
         CREB   NF-1   CP2   HOXA5   Lmo2   Nkx2-5   ZID   NF-kappaB   NF-kappaB1   c-Ets-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCCDC12 promoter sequence
   Search Chromatin IP Primers for CCDC12

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CCDC12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.31   Ensembl cytogenetic band:  3p21.31   HGNC cytogenetic band: 3p21.31

CCDC12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCDC12 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M046939:  view genomic region     (about GC identifiers)

Start:
46,963,216 bp from pter      End:
47,023,500 bp from pter
Size:
60,285 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CCD12_HUMAN, Q8WUD4 (See protein sequence)
Recommended Name: Coiled-coil domain-containing protein 12  
Size: 166 amino acids; 19181 Da
Secondary accessions: Q8N8I4

Explore the universe of human proteins at neXtProt for CCDC12: NX_Q8WUD4

Explore proteomics data for CCDC12 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CCDC12 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001264003.1  NP_653317.2  

    ENSEMBL proteins: 
     ENSP00000416263   ENSP00000387490   ENSP00000473887   ENSP00000292314   ENSP00000441327  

    CCDC12 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Purified Protein for CCDC12
    OriGene Protein Over-expression Lysate for CCDC12
    OriGene MassSpec for CCDC12
    OriGene Custom Protein Services for CCDC12
    GenScript Custom Purified and Recombinant Proteins Services for CCDC12
    Novus Biologicals CCDC12 Protein
    Novus Biologicals CCDC12 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CCDC12

     
    Search eBioscience for Proteins for CCDC12 

    CCDC12 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for CCDC12
    Novus Biologicals CCDC12 Antibodies
    Abcam antibodies for CCDC12
    Cloud-Clone Corp. Antibodies for CCDC12
    Search ThermoFisher Antibodies for CCDC12
    LSBio Antibodies in human, mouse, rat for CCDC12

    CCDC12 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CCDC12
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CCDC12
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CCDC12
    Cloud-Clone Corp. CLIAs for CCDC12
    Search eBioscience for ELISAs for CCDC12 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR013169 mRNA_splic_Cwf18

    Graphical View of Domain Structure for InterPro Entry Q8WUD4

    ProtoNet protein and cluster: Q8WUD4


    Find genes that share domains with CCDC12           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    Find genes that share ontologies with CCDC12           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for CCDC12:
     Decreased Hepatitis C virus re  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CCDC12
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CCDC12

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CCDC12
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CCDC12

    miRNA
    Products:
        
    miRTarBase miRNAs that target CCDC12:
    hsa-mir-326 (MIRT043621)

    Block miRNA regulation of human, mouse, rat CCDC12 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate CCDC12:
    hsa-miR-138-2*
    SwitchGear 3'UTR luciferase reporter plasmidCCDC12 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CCDC12
    Predesigned siRNA for gene silencing in human, mouse, rat CCDC12

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CCDC12

    Clone
    Products:
         
    OriGene clones in human, mouse for CCDC12 (see all 9)
    OriGene ORF clones in mouse, rat for CCDC12
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): CCDC12 (NM_024584)
    Sino Biological Human cDNA Clone for CCDC12
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCDC12
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC12

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for CCDC12
    Browse ESI BIO Cell Lines and PureStem Progenitors for CCDC12 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC12


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CCDC12 About    
    See pathways by source

    SuperPathContained pathways About
    1Spliceosome
    Spliceosome


    Find genes that share SuperPaths with CCDC12           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    1 Kegg Pathway  (Kegg details for CCDC12):
        Spliceosome

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CCDC12
    Interactions:

        Search GeneGlobe Interaction Network for CCDC12

    STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

    Selected Interacting proteins for CCDC12 (Q8WUD41, 2, 3 ENSP000002923144) via UniProtKB, MINT, STRING, and/or I2D (see all 17)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CRNKL1Q9BZJ01, 2, ENSP000003665574EBI-2557572,EBI-1049701 MINT-8337101 MINT-8332064 STRING: ENSP00000366557
    ATG5Q9H1Y03, ENSP000003433134I2D: score=1 STRING: ENSP00000343313
    CDC5LENSP000003605324STRING: ENSP00000360532
    TCERG1LENSP000003576314STRING: ENSP00000357631
    PRPF19ENSP000002275244STRING: ENSP00000227524
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CCDC12 (CCD12)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CCDC12 gene (2 alternative transcripts): 
    NM_001277074.1  NM_144716.5  

    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000425441(uc003cqo.2) ENST00000604367 ENST00000605358 ENST00000488069(uc011baq.2)
    ENST00000603885 ENST00000446836 ENST00000494655(uc011bar.1) ENST00000604164
    ENST00000604181 ENST00000605875 ENST00000460035 ENST00000492819 ENST00000292314
    ENST00000546280
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CCDC12 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate CCDC12:
    hsa-miR-138-2*
    SwitchGear 3'UTR luciferase reporter plasmidCCDC12 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CCDC12
    Predesigned siRNA for gene silencing in human, mouse, rat CCDC12
    Clone
    Products:
         
    OriGene clones in human, mouse for CCDC12 (see all 9)
    OriGene ORF clones in mouse, rat for CCDC12
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): CCDC12 (NM_024584)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCDC12
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC12
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CCDC12
    OriGene qSTAR qPCR primer pairs in human, mouse for CCDC12
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CCDC12
      QuantiTect SYBR Green Assays in human, mouse, rat CCDC12
      QuantiFast Probe-based Assays in human, mouse, rat CCDC12

    Selected AceView cDNA sequences (see all 145):

    BM830766 CD108843 BM769733 AK098120 W72343 BM768997 BM676030 BM712682 
    W19909 BM718147 C02159 BU601082 AA039474 AI128891 AA831695 BM798999 
    BX098833 N26202 CA434128 BM712629 BQ642425 BU687618 BU738349 BC020830 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CCDC12 (see all 8)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b
    SP1:                          -     -     -     -     -           -           -     -                 -                     
    SP2:                                            -     -           -           -     -                 -                     
    SP3:                          -     -     -     -     -           -           -     -                                       
    SP4:                                            -     -           -           -     -                                       
    SP5:                                                              -           -     -                                       


    ECgene alternative splicing isoforms for CCDC12

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CCDC12 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCGTGGGAAC
    CCDC12 Expression
    About this image

    CCDC12 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CCDC12 Protein Expression
        Custom PCR Arrays for CCDC12
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for CCDC12
    OriGene qSTAR qPCR primer pairs in human, mouse for CCDC12
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CCDC12
    QuantiTect SYBR Green Assays in human, mouse, rat CCDC12
    QuantiFast Probe-based Assays in human, mouse, rat CCDC12
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC12

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CCDC12 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ccdc121 , 5 coiled-coil domain containing 121, 5 87.95(n)1
    90.36(a)1
      9 (60.37 cM)5
    726541  NM_028312.31  NP_082588.21 
     1106565035 
    chicken
    (Gallus gallus)
    Aves CCDC121 coiled-coil domain containing 12 71.34(n)
    71.34(a)
      420402  NM_001006353.1  NP_001006353.1 
    lizard
    (Anolis carolinensis)
    Reptilia CCDC126
    coiled-coil domain containing 12
    63(a)
    1 ↔ 1
    GL343687.1(34957-62308)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.144142 Xenopus laevis transcribed sequence with weak similarity more 76.97(n)    BQ729204.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ccdc121 coiled-coil domain containing 12 65.77(n)
    69.13(a)
      793027  NM_001003589.2  NP_001003589.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG155251 CG15525 53.9(n)
    48.23(a)
      43556  NM_143500.4  NP_651757.1 
    worm
    (Caenorhabditis elegans)
    Secernentea Y69A2AR.216
    Protein Y69A2AR.21 (Y69A2AR.21) mRNA, complete cds...
    37(a)
    1 ↔ 1
    IV(2494517-2495174) WBGene00022092


    ENSEMBL Gene Tree for CCDC12 (if available)
    TreeFam Gene Tree for CCDC12 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CCDC12 gene

    Find genes that share paralogs with CCDC12           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for CCDC12
    PGOHUM00000240042


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CCDC12 (see all 1129)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1878337791,2
    --46893508(+) AGGGTA/CTCTGT 2 -- int10--------
    rs1921743161,2
    --46893517(+) GTCCTA/GGGGGA 2 -- int10--------
    rs358813851,2
    C--46893535(+) TAGCT-/CTGACTG 2 -- int10--------
    rs342070781,2
    C,F--46893601(+) CCAGCG/AGCATC 2 -- int13Minor allele frequency- A:0.02NA WA 240
    rs1455432841,2
    --46893739(+) GAGGTA/CTTAAA 2 -- int10--------
    rs64420401,2
    C,F,A,H--46893809(+) ATGGAA/CTGGGC 2 -- int125Minor allele frequency- C:0.43NS EA NA WA CSA 2356
    rs1488803081,2
    --46893834(+) AGAAGA/GCAGCC 2 -- int10--------
    rs758001601,2
    F--46893836(+) AAGGCA/GGCCCT 2 -- int11Minor allele frequency- G:0.02WA 118
    rs1423127691,2
    C--46893842(+) GCCCTA/GAGTGT 2 -- int10--------
    rs756457751,2
    F--46893884(+) CCAACA/GCAGGG 2 -- int11Minor allele frequency- G:0.07WA 118

    HapMap Linkage Disequilibrium report for CCDC12 (46963216 - 47023500 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for CCDC12 (see all 12):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2657344CNV Deletion23128226
    esv25200CNV Loss19812545
    nsv460526CNV Loss19166990
    dgv5130n71CNV Loss21882294
    nsv876755CNV Loss21882294
    nsv3800CNV Loss18451855
    nsv428417CNV Loss18775914
    nsv876757CNV Loss21882294
    nsv876756CNV Gain21882294
    nsv876754CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CCDC12
    DNA2.0 Custom Variant and Variant Library Synthesis for CCDC12

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615470    OMIM disorders: --


    Find genes that share disorders with CCDC12           About GenesLikeMe


    Export disorders for CCDC12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CCDC12 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with CCDC12)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    5. Dynamic protein-protein interaction wiring of the human spliceosome. (PubMed id 22365833)1 Hegele A....Stelzl U. (Mol. Cell 2012)
    6. Isolation of siRNA target by biotinylated siRNA reveals that human CCDC12 promotes early erythroid differentiation. (PubMed id 22269669)1 Fan C....Chen M. (Leuk. Res. 2012)
    7. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    8. Identification of VKORC1 interaction partners by split-ubiquitin system and coimmunoprecipitation. (PubMed id 21103663)1 Schaafhausen A....MA1ller C.R. (Thromb. Haemost. 2011)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 151903 HGNC: 28332 AceView: MGC23918 Ensembl:ENSG00000160799 euGenes: HUgn151903
    ECgene: CCDC12 Kegg: 151903 H-InvDB: CCDC12

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CCDC12 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CCDC12 gene:
    Search GeneIP for patents involving CCDC12

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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