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Aliases for CCDC116 Gene

Aliases for CCDC116 Gene

  • Coiled-Coil Domain Containing 116 2 3

External Ids for CCDC116 Gene

Previous GeneCards Identifiers for CCDC116 Gene

  • GC22P020317
  • GC22P021987
  • GC22P004944

Summaries for CCDC116 Gene

GeneCards Summary for CCDC116 Gene

CCDC116 (Coiled-Coil Domain Containing 116) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC116 Gene

Genomics for CCDC116 Gene

Regulatory Elements for CCDC116 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for CCDC116 Gene

21,632,716 bp from pter
21,637,327 bp from pter
4,612 bases
Plus strand

Genomic View for CCDC116 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC116 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC116 Gene

Proteins for CCDC116 Gene

  • Protein details for CCDC116 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 116
    Protein Accession:
    Secondary Accessions:
    • B7Z7H5
    • Q8N9Y9

    Protein attributes for CCDC116 Gene

    515 amino acids
    Molecular mass:
    56940 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CCDC116 Gene


neXtProt entry for CCDC116 Gene

Proteomics data for CCDC116 Gene at MOPED

Post-translational modifications for CCDC116 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC116 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC116 Gene

Domains for CCDC116 Gene

Protein Domains for CCDC116 Gene


Suggested Antigen Peptide Sequences for CCDC116 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC116: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC116 Gene

Function for CCDC116 Gene

Gene Ontology (GO) - Molecular Function for CCDC116 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with CCDC116: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC116

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC116 Gene

Localization for CCDC116 Gene

Subcellular locations from

Jensen Localization Image for CCDC116 Gene COMPARTMENTS Subcellular localization image for CCDC116 gene
Compartment Confidence
nucleus 3
cytosol 1

Gene Ontology (GO) - Cellular Components for CCDC116 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005813 centrosome IDA 25074808
genes like me logo Genes that share ontologies with CCDC116: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for CCDC116 Gene

Pathways for CCDC116 Gene

SuperPathways for CCDC116 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC116 Gene


No data available for Pathways by source for CCDC116 Gene

Transcripts for CCDC116 Gene

mRNA/cDNA for CCDC116 Gene

(5) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(15) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC116 Gene

Coiled-coil domain containing 116:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC116

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC116 Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3a · 3b ^ 4 ^ 5
SP1: - -
SP2: -

Relevant External Links for CCDC116 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC116 Gene

mRNA expression in normal human tissues for CCDC116 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC116 Gene

This gene is overexpressed in Testis (26.2).

Protein differential expression in normal tissues for CCDC116 Gene

This gene is overexpressed in Cervix (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CCDC116 Gene

SOURCE GeneReport for Unigene cluster for CCDC116 Gene Hs.131615

genes like me logo Genes that share expressions with CCDC116: view

Expression partners for CCDC116 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for CCDC116 Gene

Orthologs for CCDC116 Gene

This gene was present in the common ancestor of mammals.

Orthologs for CCDC116 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC116 35
  • 73.86 (n)
  • 65.55 (a)
CCDC116 36
  • 66 (a)
(Canis familiaris)
Mammalia CCDC116 35
  • 76.35 (n)
  • 66.48 (a)
CCDC116 36
  • 47 (a)
(Mus musculus)
Mammalia Ccdc116 35
  • 74.9 (n)
  • 69.77 (a)
Ccdc116 16
Ccdc116 36
  • 54 (a)
(Pan troglodytes)
Mammalia CCDC116 35
  • 98.87 (n)
  • 97.62 (a)
CCDC116 36
  • 94 (a)
(Rattus norvegicus)
Mammalia Ccdc116 35
  • 74.49 (n)
  • 68.94 (a)
(Monodelphis domestica)
Mammalia CCDC116 36
  • 25 (a)
Species with no ortholog for CCDC116:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC116 Gene

Gene Tree for CCDC116 (if available)
Gene Tree for CCDC116 (if available)

Paralogs for CCDC116 Gene

(1) SIMAP similar genes for CCDC116 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with CCDC116: view

No data available for Paralogs for CCDC116 Gene

Variants for CCDC116 Gene

Sequence variations from dbSNP and Humsavar for CCDC116 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type MAF
VAR_061578 -
VAR_028807 -
VAR_028806 -
VAR_028805 -
VAR_028804 -

Structural Variations from Database of Genomic Variants (DGV) for CCDC116 Gene

Variant ID Type Subtype PubMed ID
nsv7350 OTHER Inversion 18451855
nsv914458 CNV Loss 21882294
dgv4881n71 CNV Loss 21882294
nsv516806 CNV Loss 19592680
dgv4882n71 CNV Loss 21882294
nsv914469 CNV Loss 21882294

Relevant External Links for CCDC116 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC116 Gene

Disorders for CCDC116 Gene

No disorders were found for CCDC116 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for CCDC116 Gene

Publications for CCDC116 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Proteomic analysis of mammalian sperm cells identifies new components of the centrosome. (PMID: 25074808) Firat-Karalar E.N. … Stearns T. (J. Cell Sci. 2014) 2 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I. … Wright H. (Nature 1999) 4

Products for CCDC116 Gene

Sources for CCDC116 Gene

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