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CCDC114 Gene

protein-coding   GIFtS: 47
GCID: GC19M048799

Coiled-Coil Domain Containing 114

  See CCDC114-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Coiled-Coil Domain Containing 1141 2
CILD202 5
Coiled-Coil Domain-Containing Protein 1142

External Ids:    HGNC: 265601   Entrez Gene: 932332   Ensembl: ENSG000001054797   OMIM: 6150385   UniProtKB: Q96M633   
ORGUL members:         

Export aliases for CCDC114 gene to outside databases

Previous GC identifers: GC19M053492 GC19M045180


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CCDC114 Gene:
This gene encodes a coiled-coil domain-containing protein that is a component of the outer dynein arm docking
complex in cilia cells. Mutations in this gene may cause primary ciliary dyskinesia 20. (provided by RefSeq, May
2013)

GeneCards Summary for CCDC114 Gene:
CCDC114 (coiled-coil domain containing 114) is a protein-coding gene. Diseases associated with CCDC114 include ciliary dyskinesia, primary, 20, and hypermethioninemia. An important paralog of this gene is CCDC63.

UniProtKB/Swiss-Prot: CC114_HUMAN, Q96M63
Function: Probable component of the outer dynein arm complex required along the entire axoneme for tethering of
outer dynein arms (Probable)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NT_011109.17  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CCDC114 gene promoter:
         COUP-TF1   STAT1   Bach2   RelA   HNF-4alpha1   E47   AREB6   RORalpha1   HEN1   COUP-TF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCCDC114 promoter sequence
   Search Chromatin IP Primers for CCDC114

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CCDC114


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.33   Ensembl cytogenetic band:  19q13.33   HGNC cytogenetic band: 19q13.32

CCDC114 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCDC114 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M048799:  view genomic region     (about GC identifiers)

Start:
48,799,709 bp from pter      End:
48,825,151 bp from pter
Size:
25,443 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CC114_HUMAN, Q96M63 (See protein sequence)
Recommended Name: Coiled-coil domain-containing protein 114  
Size: 670 amino acids; 75046 Da
Caution: Although the CILD20 variant corresponding to dbSNP:rs147718607 could create a Ala to Thr substitution at
position 248, the variation causes an intronic insertion, resulting in a frameshift and premature truncation. It
should therefore not be considered as a single amino acid polymorphism (SAP) (PubMed:23261303)
Sequence caution: Sequence=BAB71448.1; Type=Miscellaneous discrepancy; Note=Unlikely isoform. Aberrant splice
sites; Sequence=BAC87296.1; Type=Miscellaneous discrepancy; Note=Unlikely isoform. Aberrant splice sites;
Secondary accessions: Q6ZRL4 Q96M06 Q9UFG8
Alternative splicing: 3 isoforms:  Q96M63-1   Q96M63-4   Q96M63-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CCDC114: NX_Q96M63

Explore proteomics data for CCDC114 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CCDC114 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_653178.3  
    ENSEMBL proteins: 
     ENSP00000318429  

    CCDC114 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for CCDC114

     
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    Search eBioscience for ELISAs for CCDC114 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: Q96M63

    UniProtKB/Swiss-Prot: CC114_HUMAN, Q96M63
    Similarity: Belongs to the ODA1/DCC2 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CC114_HUMAN, Q96M63
    Function: Probable component of the outer dynein arm complex required along the entire axoneme for tethering of
    outer dynein arms (Probable)

    Animal Models:

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CCDC114
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CCDC114

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CCDC114
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CCDC114

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidCCDC114 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CCDC114

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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CCDC114 (NM_144577)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCDC114
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC114

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for CCDC114 
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    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC114


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CC114_HUMAN, Q96M63: Cell projection, cilium
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton4
    nucleus3
    cytosol2
    golgi apparatus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005929cilium IDA--
    GO:0036157outer dynein arm IMP--

    Find genes that share ontologies with CCDC114           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CCDC114
    Interactions:

        Search GeneGlobe Interaction Network for CCDC114

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0036158outer dynein arm assembly IMP--

    Find genes that share ontologies with CCDC114           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CCDC114 (CC114)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CCDC114 gene (3 alternative transcripts): 
    NM_144577.3  NM_001135193.1  NM_001135194.1  

    Unigene Cluster for CCDC114:

    Coiled-coil domain containing 114
    Hs.112645  [show with all ESTs]
    Unigene Representative Sequence: BC007730
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000315396(uc002piq.2 uc002pir.2) ENST00000474199(uc002pio.3 uc002pit.1 uc002piu.1)
    ENST00000497273(uc002pis.1) ENST00000504608 ENST00000497803 ENST00000483610

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CCDC114 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate CCDC114
    SwitchGear 3'UTR luciferase reporter plasmidCCDC114 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for CCDC114
    Predesigned siRNA for gene silencing in human, mouse, rat CCDC114
    Clone
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    OriGene clones in human, mouse for CCDC114 (see all 10)
    OriGene ORF clones in mouse, rat for CCDC114
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CCDC114 (NM_144577)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCDC114
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC114
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for CCDC114
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CCDC114
      QuantiTect SYBR Green Assays in human, mouse, rat CCDC114
      QuantiFast Probe-based Assays in human, mouse, rat CCDC114

    Additional mRNA sequence: 

    AK057488.1 BC007730.2 

    7 DOTS entries:

    DT.95158637  DT.101980943  DT.65284543  DT.95309182  DT.121454765  DT.40121903  DT.121454761 

    18 AceView cDNA sequences:

    AK057488 AI669605 BC025752 CA440066 AL122083 CD243987 NM_144577 AK128144 
    BC031619 BI831110 AK057357 AI801593 BG772128 BC007730 BM926487 BI766244 
    BF686049 BF852637 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CCDC114 (see all 10)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^
    SP1:                                                                                      -     -                                         -                 -   
    SP2:                                                  -                                   -     -                                         -                 -   
    SP3:                                      -           -                                   -     -                                                               
    SP4:                                      -           -                                                                                                         
    SP5:                    -                             -                                                                                                         

    ExUns: 17 ^ 18 ^ 19 ^ 20
    SP1:                        
    SP2:                        
    SP3:                        
    SP4:                        
    SP5:                        


    ECgene alternative splicing isoforms for CCDC114

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CCDC114 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CCDC114 Expression
    About this image


    CCDC114 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             Metencephalon
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Medulla Oblongata
    CCDC114 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CCDC114 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.112645
        Custom PCR Arrays for CCDC114
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC114

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CCDC114 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ccdc1141 , 5 coiled-coil domain containing 1141, 5 72.96(n)1
    64.82(a)1
      7 (29.60 cM)5
    2115351  NM_001033243.21  NP_001028415.11 
     459240725 
    lizard
    (Anolis carolinensis)
    Reptilia CCDC1146
    coiled-coil domain containing 114
    24(a)
    1 ↔ 1
    GL343329.1(213732-256627)
    zebrafish
    (Danio rerio)
    Actinopterygii CCDC1146
    coiled-coil domain containing 114
    25(a)
    1 ↔ 1
    11(42189798-42204454) ENSDARG00000015010
    fruit fly
    (Drosophila melanogaster)
    Insecta CG149056
    CG170836
    --
    21(a)
    17(a)
    many ↔ many
    many ↔ many
    3R(12448457-12450439)
    3R(19111815-19113773)


    ENSEMBL Gene Tree for CCDC114 (if available)
    TreeFam Gene Tree for CCDC114 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CCDC114 gene
    CCDC632  

    Find genes that share paralogs with CCDC114           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CCDC114 (see all 713)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1907363211,2
    --48799386(+) AACATC/GGTGAA 1 -- int10--------
    rs1815123711,2
    --48799432(+) GCGTGC/GTAGTG 1 -- int10--------
    rs1845917581,2
    --48799469(+) AGGCTA/GAGGCA 1 -- int10--------
    rs1389158561,2
    C--48799568(+) ATCTC-/AATA  
            
    AATAA
    1 -- int10--------
    rs45725151,2
    C,F--48799605(+) AAGAAC/TGCTGA 1 -- int16Minor allele frequency- T:0.36NA WA CSA EA 363
    rs776904841,2
    C,F--48799621(+) TGAGTG/AAATGA 1 -- int11Minor allele frequency- A:0.02NA 120
    rs1154781591,2
    F--48799640(+) ATGAAT/CGAATG 1 -- int11Minor allele frequency- C:0.08WA 118
    rs22921121,2
    C,F,H--48799716(+) AAGCCG/AGCTCT 1 -- ut3122Minor allele frequency- A:0.45EA NS NA WA CSA 3838
    rs1885130421,2
    --48799726(+) TCCACA/CCATAT 1 -- ut310--------
    rs1812843271,2
    --48799778(+) GTCTTC/TGCCCT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for CCDC114 (48799709 - 48825151 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for CCDC114:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv833854CNV Loss17160897
    esv34181CNV Loss18971310
    nsv9739CNV Gain+Loss18304495
    nsv469623CNV Complex16826518

    Human Gene Mutation Database (HGMD): CCDC114
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CCDC114
    DNA2.0 Custom Variant and Variant Library Synthesis for CCDC114

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615038   
    OMIM disorders: 615067  
    UniProtKB/Swiss-Prot: CC114_HUMAN, Q96M63
  • Ciliary dyskinesia, primary, 20 (CILD20) [MIM:615067]: A disorder characterized by abnormalities of
    motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to
    defects in the respiratory cilia. Patients may exhibit randomization of left-right body asymmetry and situs
    inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs
    inversus is referred to as Kartagener syndrome. Unlike other forms of CILD characterized by reduced fertility,
    patients with CILD20 do not appear to be infertile. Note=The disease is caused by mutations affecting the gene
    represented in this entry

  • 3 diseases for CCDC114:    
    About MalaCards
    ciliary dyskinesia, primary, 20    hypermethioninemia    ciliary dyskinesia, primary, 19

    1 disease from the University of Copenhagen DISEASES database for CCDC114:
    Primary ciliary dyskinesia

    Find genes that share disorders with CCDC114           About GenesLikeMe

    Genetic Association Database (GAD): CCDC114
    Human Genome Epidemiology (HuGE) Navigator: CCDC114 (3 documents)

    Export disorders for CCDC114 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CCDC114 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with CCDC114)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Splice-Site mutations in the axonemal outer dynein arm docking complex gene CCDC114 cause primary ciliary dyskinesia. (PubMed id 23261303)1, 2, 3 Onoufriadis A.... Mitchison H.M. (Am. J. Hum. Genet. 2013)
    2. Exome sequencing identifies mutations in CCDC114 as a cause of primary ciliary dyskinesia. (PubMed id 23261302)1, 2, 3 Knowles M.R.... Zariwala M.A. (Am. J. Hum. Genet. 2013)
    3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Loss-of-function mutations in CCDC114 cause primary ciliary dyskinesia. (PubMed id 23506398)1 Wu D.H. and Singaraja R.R. (Clin. Genet. 2013)
    6. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    7. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 93233 HGNC: 26560 AceView: FLJ32926 Ensembl:ENSG00000105479 euGenes: HUgn93233
    ECgene: CCDC114 H-InvDB: CCDC114

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CCDC114 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CCDC114 gene:
    Search GeneIP for patents involving CCDC114

    GeneCards and IP:
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