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Aliases for CCDC113 Gene

Aliases for CCDC113 Gene

  • Coiled-Coil Domain Containing 113 2 3
  • Coiled-Coil Domain-Containing Protein 113 3
  • HSPC065 3

External Ids for CCDC113 Gene

Previous GeneCards Identifiers for CCDC113 Gene

  • GC16P056842
  • GC16P058283
  • GC16P044152

Summaries for CCDC113 Gene

GeneCards Summary for CCDC113 Gene

CCDC113 (Coiled-Coil Domain Containing 113) is a Protein Coding gene.

UniProtKB/Swiss-Prot for CCDC113 Gene

  • Component of centriolar satellites contributing to primary cilium formation.

Gene Wiki entry for CCDC113 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC113 Gene

Genomics for CCDC113 Gene

Regulatory Elements for CCDC113 Gene

Genomic Location for CCDC113 Gene

Start:
58,231,157 bp from pter
End:
58,283,836 bp from pter
Size:
52,680 bases
Orientation:
Plus strand

Genomic View for CCDC113 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC113 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC113 Gene

Proteins for CCDC113 Gene

  • Protein details for CCDC113 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H0I3-CC113_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 113
    Protein Accession:
    Q9H0I3
    Secondary Accessions:
    • B2RAQ7
    • B4DR20
    • Q9NZX2

    Protein attributes for CCDC113 Gene

    Size:
    377 amino acids
    Molecular mass:
    44220 Da
    Quaternary structure:
    • Interacts with HAP1 and PCM1.
    SequenceCaution:
    • Sequence=AAF29037.1; Type=Frameshift; Positions=187; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC113 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC113 Gene

Proteomics data for CCDC113 Gene at MOPED

Post-translational modifications for CCDC113 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC113 Gene

No data available for DME Specific Peptides for CCDC113 Gene

Domains for CCDC113 Gene

Protein Domains for CCDC113 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CCDC113 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC113: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC113 Gene

Function for CCDC113 Gene

Molecular function for CCDC113 Gene

UniProtKB/Swiss-Prot Function: Component of centriolar satellites contributing to primary cilium formation.

Gene Ontology (GO) - Molecular Function for CCDC113 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25074808
genes like me logo Genes that share ontologies with CCDC113: view

Animal Model Products

CRISPR Products

miRNA for CCDC113 Gene

miRTarBase miRNAs that target CCDC113

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC113

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for CCDC113 Gene

Localization for CCDC113 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CCDC113 Gene

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Note=Colocalized with HAP1 at centriolar satellites. Centriolar satellite localization requires PCM1. {ECO:0000269 PubMed:25074808}.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC113 Gene COMPARTMENTS Subcellular localization image for CCDC113 gene
Compartment Confidence
cytosol 4
nucleus 4
endoplasmic reticulum 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for CCDC113 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IDA --
GO:0034451 centriolar satellite IMP 25074808
GO:0043234 protein complex IDA --
genes like me logo Genes that share ontologies with CCDC113: view

Pathways for CCDC113 Gene

SuperPathways for CCDC113 Gene

No Data Available

Interacting Proteins for CCDC113 Gene

Selected Interacting proteins: Q9H0I3-CC113_HUMAN for CCDC113 Gene via I2D

Gene Ontology (GO) - Biological Process for CCDC113 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0042384 cilium assembly IMP 25074808
genes like me logo Genes that share ontologies with CCDC113: view

No data available for Pathways by source for CCDC113 Gene

Transcripts for CCDC113 Gene

Unigene Clusters for CCDC113 Gene

Coiled-coil domain containing 113:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC113

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC113 Gene

No ASD Table

Relevant External Links for CCDC113 Gene

GeneLoc Exon Structure for
CCDC113
ECgene alternative splicing isoforms for
CCDC113

Expression for CCDC113 Gene

mRNA expression in normal human tissues for CCDC113 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCDC113 Gene

This gene is overexpressed in Testis (8.3).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for CCDC113 Gene

SOURCE GeneReport for Unigene cluster for CCDC113 Gene Hs.11614

genes like me logo Genes that share expressions with CCDC113: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for CCDC113 Gene

Orthologs for CCDC113 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC113 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC113 35
  • 99.29 (n)
  • 98.41 (a)
CCDC113 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC113 35
  • 83.02 (n)
  • 80.9 (a)
CCDC113 36
  • 78 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC113 35
  • 87.57 (n)
  • 83.51 (a)
CCDC113 36
  • 78 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc113 35
  • 81.79 (n)
  • 77.98 (a)
Ccdc113 16
Ccdc113 36
  • 78 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC113 36
  • 60 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC113 36
  • 61 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc113 35
  • 77.57 (n)
  • 72.34 (a)
chicken
(Gallus gallus)
Aves CCDC113 35
  • 57.85 (n)
  • 42.82 (a)
CCDC113 36
  • 41 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC113 36
  • 51 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc113 35
  • 59.09 (n)
  • 51.51 (a)
Str.12836 35
zebrafish
(Danio rerio)
Actinopterygii ccdc113 35
  • 51.11 (n)
  • 39.7 (a)
ccdc113 36
  • 37 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 42 (a)
OneToOne
Species with no ortholog for CCDC113:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC113 Gene

ENSEMBL:
Gene Tree for CCDC113 (if available)
TreeFam:
Gene Tree for CCDC113 (if available)

Paralogs for CCDC113 Gene

No data available for Paralogs for CCDC113 Gene

Variants for CCDC113 Gene

Sequence variations from dbSNP and Humsavar for CCDC113 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs889590 -- 58,249,232(+) ACCAA(C/T)TGTAC upstream-variant-2KB
rs889591 -- 58,249,237(+) CTGTA(C/G)CAGAT upstream-variant-2KB
rs1062238 -- 58,278,573(-) AGATC(A/T)TCTCC reference, missense
rs1125849 -- 58,258,310(-) GTGTC(C/T)TCTAA intron-variant
rs1834018 -- 58,273,338(+) GTGGT(A/G)TTCCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC113 Gene

Variant ID Type Subtype PubMed ID
esv2714548 CNV Deletion 23290073
esv6424 CNV Loss 19470904
esv2672427 CNV Deletion 23128226

Relevant External Links for CCDC113 Gene

HapMap Linkage Disequilibrium report
CCDC113

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC113 Gene

Disorders for CCDC113 Gene

Relevant External Links for CCDC113

Genetic Association Database (GAD)
CCDC113
genes like me logo Genes that share disorders with CCDC113: view

No data available for UniProtKB/Swiss-Prot for CCDC113 Gene

Publications for CCDC113 Gene

  1. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PMID: 11042152) Zhang Q.-H. … Chen Z. (Genome Res. 2000) 2 3 4
  2. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4
  3. Proteomic analysis of mammalian sperm cells identifies new components of the centrosome. (PMID: 25074808) Firat-Karalar E.N. … Stearns T. (J. Cell Sci. 2014) 2 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. From ORFeome to biology: a functional genomics pipeline. (PMID: 15489336) Wiemann S. … Poustka A. (Genome Res. 2004) 3

Products for CCDC113 Gene

  • antibodies-online proteins for CCDC113
  • antibodies-online antibodies for CCDC113
  • antibodies-online kits for CCDC113

Sources for CCDC113 Gene

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