Free for academic non-profit institutions. Other users need a Commercial license

Aliases for CCDC113 Gene

Aliases for CCDC113 Gene

  • Coiled-Coil Domain Containing 113 2 3 5
  • HSPC065 3

External Ids for CCDC113 Gene

Previous GeneCards Identifiers for CCDC113 Gene

  • GC16P056842
  • GC16P058283
  • GC16P044152

Summaries for CCDC113 Gene

GeneCards Summary for CCDC113 Gene

CCDC113 (Coiled-Coil Domain Containing 113) is a Protein Coding gene.

UniProtKB/Swiss-Prot for CCDC113 Gene

  • Component of centriolar satellites contributing to primary cilium formation.

Gene Wiki entry for CCDC113 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC113 Gene

Genomics for CCDC113 Gene

Regulatory Elements for CCDC113 Gene

Promoters for CCDC113 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CCDC113 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC113 Gene

Chromosome:
16
Start:
58,196,964 bp from pter
End:
58,283,836 bp from pter
Size:
86,873 bases
Orientation:
Plus strand

Genomic View for CCDC113 Gene

Genes around CCDC113 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC113 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC113 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC113 Gene

Proteins for CCDC113 Gene

  • Protein details for CCDC113 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H0I3-CC113_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 113
    Protein Accession:
    Q9H0I3
    Secondary Accessions:
    • B2RAQ7
    • B4DR20
    • Q9NZX2

    Protein attributes for CCDC113 Gene

    Size:
    377 amino acids
    Molecular mass:
    44220 Da
    Quaternary structure:
    • Interacts with HAP1 and PCM1.
    SequenceCaution:
    • Sequence=AAF29037.1; Type=Frameshift; Positions=187; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC113 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC113 Gene

Proteomics data for CCDC113 Gene at MOPED

Post-translational modifications for CCDC113 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC113 Gene

No data available for DME Specific Peptides for CCDC113 Gene

Domains & Families for CCDC113 Gene

Protein Domains for CCDC113 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CCDC113 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC113: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC113 Gene

Function for CCDC113 Gene

Molecular function for CCDC113 Gene

UniProtKB/Swiss-Prot Function:
Component of centriolar satellites contributing to primary cilium formation.
genes like me logo Genes that share phenotypes with CCDC113: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC113 Gene

Localization for CCDC113 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CCDC113 Gene

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Note=Colocalized with HAP1 at centriolar satellites. Centriolar satellite localization requires PCM1. {ECO:0000269 PubMed:25074808}.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC113 Gene COMPARTMENTS Subcellular localization image for CCDC113 gene
Compartment Confidence
nucleus 5
cytoskeleton 4
cytosol 3
endoplasmic reticulum 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for CCDC113 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IDA --
GO:0043234 protein complex IDA 25074808
genes like me logo Genes that share ontologies with CCDC113: view

Pathways & Interactions for CCDC113 Gene

SuperPathways for CCDC113 Gene

No Data Available

Interacting Proteins for CCDC113 Gene

Selected Interacting proteins: Q9H0I3-CC113_HUMAN for CCDC113 Gene via I2D

Gene Ontology (GO) - Biological Process for CCDC113 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC113 Gene

Drugs & Compounds for CCDC113 Gene

No Compound Related Data Available

Transcripts for CCDC113 Gene

Unigene Clusters for CCDC113 Gene

Coiled-coil domain containing 113:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC113 Gene

No ASD Table

Relevant External Links for CCDC113 Gene

GeneLoc Exon Structure for
CCDC113
ECgene alternative splicing isoforms for
CCDC113

Expression for CCDC113 Gene

mRNA expression in normal human tissues for CCDC113 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC113 Gene

This gene is overexpressed in Testis (x8.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCDC113 Gene



SOURCE GeneReport for Unigene cluster for CCDC113 Gene Hs.11614

genes like me logo Genes that share expression patterns with CCDC113: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CCDC113 Gene

Orthologs for CCDC113 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC113 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC113 35
  • 99.29 (n)
  • 98.41 (a)
CCDC113 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC113 36
  • 78 (a)
OneToOne
CCDC113 35
  • 83.02 (n)
  • 80.9 (a)
dog
(Canis familiaris)
Mammalia CCDC113 35
  • 87.57 (n)
  • 83.51 (a)
CCDC113 36
  • 78 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc113 16
Ccdc113 35
  • 81.79 (n)
  • 77.98 (a)
Ccdc113 36
  • 78 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC113 36
  • 60 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC113 36
  • 61 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc113 35
  • 77.57 (n)
  • 72.34 (a)
chicken
(Gallus gallus)
Aves CCDC113 35
  • 57.85 (n)
  • 42.82 (a)
CCDC113 36
  • 41 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC113 36
  • 51 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc113 35
  • 59.09 (n)
  • 51.51 (a)
Str.12836 35
zebrafish
(Danio rerio)
Actinopterygii ccdc113 36
  • 37 (a)
OneToOne
ccdc113 35
  • 51.11 (n)
  • 39.7 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 42 (a)
OneToOne
Species with no ortholog for CCDC113:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC113 Gene

ENSEMBL:
Gene Tree for CCDC113 (if available)
TreeFam:
Gene Tree for CCDC113 (if available)

Paralogs for CCDC113 Gene

No data available for Paralogs for CCDC113 Gene

Variants for CCDC113 Gene

Sequence variations from dbSNP and Humsavar for CCDC113 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
VAR_030880 -
VAR_030881 -
rs734893 -- 58,227,131(-) GAGTA(A/G)CTGGA intron-variant
rs1019547 -- 58,234,855(-) ccagt(C/T)gtaAG utr-variant-5-prime
rs1125849 -- 58,258,310(-) GTGTC(C/T)TCTAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC113 Gene

Variant ID Type Subtype PubMed ID
esv2714548 CNV Deletion 23290073
esv6424 CNV Loss 19470904
esv2672427 CNV Deletion 23128226

Variation tolerance for CCDC113 Gene

Residual Variation Intolerance Score: 79.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.46; 43.22% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC113 Gene

HapMap Linkage Disequilibrium report
CCDC113

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC113 Gene

Disorders for CCDC113 Gene

Relevant External Links for CCDC113

Genetic Association Database (GAD)
CCDC113
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC113

No disorders were found for CCDC113 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC113 Gene

Publications for CCDC113 Gene

  1. Proteomic analysis of mammalian sperm cells identifies new components of the centrosome. (PMID: 25074808) Firat-Karalar E.N. … Stearns T. (J. Cell Sci. 2014) 2 3 4 67
  2. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3
  3. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PMID: 11042152) Zhang Q.-H. … Chen Z. (Genome Res. 2000) 2 3
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  5. A Y2H-seq approach defines the human protein methyltransferase interactome. (PMID: 23455924) Weimann M. … Stelzl U. (Nat. Methods 2013) 3

Products for CCDC113 Gene

Sources for CCDC113 Gene

Back to Top

Content