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Aliases for CCDC105 Gene

Aliases for CCDC105 Gene

  • Coiled-Coil Domain Containing 105 2 3

External Ids for CCDC105 Gene

Summaries for CCDC105 Gene

GeneCards Summary for CCDC105 Gene

CCDC105 (Coiled-Coil Domain Containing 105) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC105 Gene

Genomics for CCDC105 Gene

Genomic Location for CCDC105 Gene

Start:
15,010,727 bp from pter
End:
15,023,271 bp from pter
Size:
12,545 bases
Orientation:
Plus strand

Genomic View for CCDC105 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC105 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC105 Gene

Regulatory Elements for CCDC105 Gene

Proteins for CCDC105 Gene

  • Protein details for CCDC105 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IYK2-CC105_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 105
    Protein Accession:
    Q8IYK2
    Secondary Accessions:
    • Q8N7T5
    • Q8NDL5

    Protein attributes for CCDC105 Gene

    Size:
    499 amino acids
    Molecular mass:
    56909 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC105 Gene

Proteomics data for CCDC105 Gene at MOPED

Post-translational modifications for CCDC105 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC105 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC105 Gene

Domains for CCDC105 Gene

Protein Domains for CCDC105 Gene

ProtoNet:
genes like me logo Genes that share domains with CCDC105: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC105 Gene

Function for CCDC105 Gene

Phenotypes for CCDC105 Gene

GenomeRNAi human phenotypes for CCDC105:
genes like me logo Genes that share phenotypes with CCDC105: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CCDC105 Gene

Localization for CCDC105 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC105 Gene COMPARTMENTS Subcellular localization image for CCDC105 gene
Compartment Confidence
cytoskeleton 2
cytosol 2
nucleus 2

Gene Ontology (GO) - Cellular Components for CCDC105 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070062 extracellular exosome IDA 19056867
genes like me logo Genes that share ontologies with CCDC105: view

Pathways for CCDC105 Gene

SuperPathways for CCDC105 Gene

No Data Available

Interacting Proteins for CCDC105 Gene

Gene Ontology (GO) - Biological Process for CCDC105 Gene

None

No data available for Pathways by source for CCDC105 Gene

Transcripts for CCDC105 Gene

mRNA/cDNA for CCDC105 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC105 Gene

Coiled-coil domain containing 105:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC105 Gene

No ASD Table

Relevant External Links for CCDC105 Gene

GeneLoc Exon Structure for
CCDC105
ECgene alternative splicing isoforms for
CCDC105

Expression for CCDC105 Gene

mRNA expression in normal human tissues for CCDC105 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC105 Gene

This gene is overexpressed in Testis (51.6).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for CCDC105 Gene

SOURCE GeneReport for Unigene cluster for CCDC105 Gene Hs.375985

genes like me logo Genes that share expressions with CCDC105: view

Orthologs for CCDC105 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC105 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC105 36
  • 96.25 (n)
  • 94.76 (a)
CCDC105 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC105 36
  • 85.72 (n)
  • 82.63 (a)
CCDC105 37
  • 81 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC105 36
  • 85.85 (n)
  • 83.88 (a)
CCDC105 37
  • 83 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc105 36
  • 80.85 (n)
  • 79.96 (a)
Ccdc105 16
Ccdc105 37
  • 79 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC105 37
  • 52 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc105 36
  • 79.57 (n)
  • 78.63 (a)
lizard
(Anolis carolinensis)
Reptilia CCDC105 37
  • 40 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100487156 36
  • 42.63 (n)
  • 28.49 (a)
zebrafish
(Danio rerio)
Actinopterygii CCDC105 37
  • 26 (a)
OneToOne
LOC565570 36
  • 42.7 (n)
  • 29.2 (a)
Species with no ortholog for CCDC105:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC105 Gene

ENSEMBL:
Gene Tree for CCDC105 (if available)
TreeFam:
Gene Tree for CCDC105 (if available)

Paralogs for CCDC105 Gene

No data available for Paralogs for CCDC105 Gene

Variants for CCDC105 Gene

Sequence variations from dbSNP and Humsavar for CCDC105 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs725461 -- 15,015,687(-) CTTGC(C/T)CTGTC intron-variant
rs736737 -- 15,021,733(+) GAGCC(C/T)TCGGG intron-variant
rs757463 -- 15,021,762(+) GGTGG(C/G)TGGAG intron-variant
rs757464 -- 15,022,217(+) CGTCA(A/G)CACCC intron-variant
rs2079251 -- 15,016,467(+) CAGGC(A/G)TGAGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC105 Gene

Variant ID Type Subtype PubMed ID
dgv1058e1 CNV Complex 17122850
nsv518179 CNV Loss 19592680
nsv523277 CNV Loss 19592680

Relevant External Links for CCDC105 Gene

HapMap Linkage Disequilibrium report
CCDC105

Disorders for CCDC105 Gene

Relevant External Links for CCDC105

Genetic Association Database (GAD)
CCDC105
Human Genome Epidemiology (HuGE) Navigator
CCDC105
genes like me logo Genes that share disorders with CCDC105: view

No data available for UniProtKB/Swiss-Prot for CCDC105 Gene

Publications for CCDC105 Gene

  1. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PMID: 19773279) Hosgood H.D. … Lan Q. (Occup Environ Med 2009) 3 49
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Large-scale proteomics and phosphoproteomics of urinary exosomes. (PMID: 19056867) Gonzales P.A. … Knepper M.A. (J. Am. Soc. Nephrol. 2009) 3
  5. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4

Products for CCDC105 Gene

Sources for CCDC105 Gene

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