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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CCDC101 Gene

protein-coding   GIFtS: 53
GCID: GC16P028565

Coiled-Coil Domain Containing 101

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Coiled-Coil Domain Containing 1011 2
Coiled-Coil Domain-Containing Protein 1012 3
SGF292 3
STAF362 5
SAGA-Associated Factor 29 Homolog (Yeast)1
SAGA-Associated Factor 29 Homolog2

External Ids:    HGNC: 251561   Entrez Gene: 1128692   Ensembl: ENSG000001764767   OMIM: 6133745   UniProtKB: Q96ES73   

Export aliases for CCDC101 gene to outside databases

Previous GC identifers: GC16P028473 GC16P026590


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CCDC101 Gene:
CCDC101 is a subunit of 2 histone acetyltransferase complexes: the ADA2A (TADA2A; MIM 602276)-containing (ATAC)
complex and the SPT3 (SUPT3H; MIM 602947)-TAF9 (MIM 600822)-GCN5 (KAT2A; MIM 602301)/PCAF (KAT2B; MIM 602303)
acetylase (STAGA) complex. Both of these complexes contain either GCN5 or PCAF, which are paralogous
acetyltransferases (Wang et al., 2008 (PubMed 18838386)).(supplied by OMIM, Apr 2010)

GeneCards Summary for CCDC101 Gene: 
CCDC101 (coiled-coil domain containing 101) is a protein-coding gene. Diseases associated with CCDC101 include diabetic macular edema, and retinal degeneration. GO annotations related to this gene include methylated histone residue binding. An important paralog of this gene is LOC613038.

UniProtKB/Swiss-Prot: SGF29_HUMAN, Q96ES7
Function: Involved in transcriptional regulation, through association with histone acetyltransferase (HAT)
SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. Specifically recognizes and binds methylated
'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA-type complexes,
required to recruit complexes to H3K4me. May be involved in MYC-mediated oncogenic transformation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.2  NT_010393.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CCDC101 gene promoter:
         Sox5   AP-1   NCX/Ncx   NRSF form 1   Brachyury   HSF1 (long)   NRSF form 2   HEN1   HSF1short   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCCDC101 promoter sequence
   Search SABiosciences Chromatin IP Primers for CCDC101

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC101


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p11.2   Ensembl cytogenetic band:  16p11.2   HGNC cytogenetic band: 16p11.2

CCDC101 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCDC101 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P028565:  view genomic region     (about GC identifiers)

Start:
28,565,236 bp from pter      End:
28,603,111 bp from pter
Size:
37,876 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SGF29_HUMAN, Q96ES7 (See protein sequence)
Recommended Name: SAGA-associated factor 29 homolog  
Size: 293 amino acids; 33238 Da
Subunit: Interacts with TADA3L, GCN5L2, SUPT3H and MYC (By similarity). Component of some SAGA-type complexes.
Interacts with dimethylated and trimethylated 'Lys-4' of histone H3 (H3K4me2 and H3K4me3), with a preference for
the trimethylated form (H3K4me3). Component of the ADA2A-containing complex (ATAC), composed of CSRP2BP, KAT2A,
TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1
Subcellular location: Nucleus (By similarity)
6/7 PDB 3D structures from and Proteopedia for CCDC101 (see all 7):
3LX7 (3D)        3ME9 (3D)        3MEA (3D)        3MET (3D)        3MEU (3D)        3MEV (3D)    
Secondary accessions: Q96MF5

Explore the universe of human proteins at neXtProt for CCDC101: NX_Q96ES7

Explore proteomics data for CCDC101 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96ES7

  • CCDC101 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CCDC101 Protein Expression
    REFSEQ proteins: NP_612423.1  
    ENSEMBL proteins: 
     ENSP00000316114   ENSP00000455370   ENSP00000454730  

    Human Recombinant Protein Products for CCDC101: 
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    Novus Biologicals CCDC101 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    ProSpec Recombinant Protein for CCDC101
    Cloud-Clone Corp. Proteins for CCDC101 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005671Ada2/Gcn5/Ada3 transcription activator complex IDA18838386
    GO:0070461SAGA-type complex IDA18838386

    CCDC101 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for CCDC101


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR010750 SGF29_tudor-like_dom

    Graphical View of Domain Structure for InterPro Entry Q96ES7

    ProtoNet protein and cluster: Q96ES7

    UniProtKB/Swiss-Prot: SGF29_HUMAN, Q96ES7
    Domain: The SGF29 tudor-like domain mediates binding to methylated 'Lys-4' of histone H3 (H3K4me)
    Similarity: Belongs to the SGF29 family
    Similarity: Contains 1 SGF29 C-terminal domain


    CCDC101 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SGF29_HUMAN, Q96ES7
    Function: Involved in transcriptional regulation, through association with histone acetyltransferase (HAT)
    SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. Specifically recognizes and binds methylated
    'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA-type complexes,
    required to recruit complexes to H3K4me. May be involved in MYC-mediated oncogenic transformation

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0035064methylated histone residue binding IDA--
         
    CCDC101 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for CCDC101:
     Increased cell number in G2M,  

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ccdc101):
     behavior/neurological  other 

    CCDC101 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CCDC101 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CCDC101 
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    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate CCDC101:
    hsa-miR-346
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    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: CCDC101 (NM_138414)
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC101


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CCDC101

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/50 Interacting proteins for CCDC101 (Q96ES72, 3 ENSP000003161144) via UniProtKB, MINT, STRING, and/or I2D (see all 50)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H3AP684312, 3MINT-8208820 MINT-8208994 MINT-8209533 MINT-8209481 MINT-8208878 MINT-8208960 MINT-8209567 MINT-8209125 MINT-8208901 MINT-8209070 MINT-8209550 MINT-8208976 MINT-8209091 MINT-8209584 MINT-8209261 MINT-8209449 MINT-8209516 MINT-8208834 MINT-8209427 MINT-8208806 MINT-8208846 MINT-8208860 MINT-8209498 MINT-8209465 MINT-8209145 MINT-8208780 I2D: score=1 
    HIST1H3CP684312, 3MINT-8208820 MINT-8208994 MINT-8209533 MINT-8209481 MINT-8208878 MINT-8208960 MINT-8209567 MINT-8209125 MINT-8208901 MINT-8209070 MINT-8209550 MINT-8208976 MINT-8209091 MINT-8209584 MINT-8209261 MINT-8209449 MINT-8209516 MINT-8208834 MINT-8209427 MINT-8208806 MINT-8208846 MINT-8208860 MINT-8209498 MINT-8209465 MINT-8209145 MINT-8208780 I2D: score=1 
    HIST1H3DP684312, 3MINT-8208820 MINT-8208994 MINT-8209533 MINT-8209481 MINT-8208878 MINT-8208960 MINT-8209567 MINT-8209125 MINT-8208901 MINT-8209070 MINT-8209550 MINT-8208976 MINT-8209091 MINT-8209584 MINT-8209261 MINT-8209449 MINT-8209516 MINT-8208834 MINT-8209427 MINT-8208806 MINT-8208846 MINT-8208860 MINT-8209498 MINT-8209465 MINT-8209145 MINT-8208780 I2D: score=1 
    HIST1H3EP684312, 3MINT-8208820 MINT-8208994 MINT-8209533 MINT-8209481 MINT-8208878 MINT-8208960 MINT-8209567 MINT-8209125 MINT-8208901 MINT-8209070 MINT-8209550 MINT-8208976 MINT-8209091 MINT-8209584 MINT-8209261 MINT-8209449 MINT-8209516 MINT-8208834 MINT-8209427 MINT-8208806 MINT-8208846 MINT-8208860 MINT-8209498 MINT-8209465 MINT-8209145 MINT-8208780 I2D: score=1 
    HIST1H3FP684312, 3MINT-8208820 MINT-8208994 MINT-8209533 MINT-8209481 MINT-8208878 MINT-8208960 MINT-8209567 MINT-8209125 MINT-8208901 MINT-8209070 MINT-8209550 MINT-8208976 MINT-8209091 MINT-8209584 MINT-8209261 MINT-8209449 MINT-8209516 MINT-8208834 MINT-8209427 MINT-8208806 MINT-8208846 MINT-8208860 MINT-8209498 MINT-8209465 MINT-8209145 MINT-8208780 I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0043966histone H3 acetylation IDA18838386
    GO:0071169establishment of protein localization to chromatin TAS--

    CCDC101 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CCDC101 (SGF29)

    Search CenterWatch for drugs/clinical trials and news about CCDC101 / SGF29

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CCDC101 gene: 
    NM_138414.2  

    Unigene Cluster for CCDC101:

    Coiled-coil domain containing 101
    Hs.655476  [show with all ESTs]
    Unigene Representative Sequence: NM_138414
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000564682 ENST00000569581 ENST00000317058(uc002dqf.3) ENST00000567564
    ENST00000567447 ENST00000564023 ENST00000565945
    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate CCDC101:
    hsa-miR-346
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CCDC101
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC101

    Additional mRNA sequence: 

    AK057008.1 BC011981.1 

    11 DOTS entries:

    DT.315968  DT.100688685  DT.97840187  DT.92422045  DT.95254739  DT.100780474  DT.95301453  DT.100713412 
    DT.120695154  DT.75112909  DT.95217570 

    24/114 AceView cDNA sequences (see all 114):

    CA487938 BU732331 BM817525 BM694155 BU145241 BQ683488 BM708074 F34859 
    BU731928 BC011981 F36963 C15563 NM_138414 BU168503 N73629 AA039514 
    BX281524 BU182386 BI831713 AA132506 AK057008 BQ051748 BU188806 BM974021 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for CCDC101    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10
    SP1:                          -                 -                                       
    SP2:                          -                 -                                       
    SP3:                          -                                                         
    SP4:                                                                                    


    ECgene alternative splicing isoforms for CCDC101

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CCDC101 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CGCCCCCACA
    CCDC101 Expression
    About this image


    See CCDC101 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CCDC101

    SOURCE GeneReport for Unigene cluster: Hs.655476
        SABiosciences Custom PCR Arrays for CCDC101
    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC101
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC101

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for CCDC101 gene from 7/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ccdc1011 , 5 coiled-coil domain containing 1011, 5 90.78(n)1
    98.29(a)1
      7 (69.23 cM)5
    755651  NM_029339.31  NP_083615.31 
     1266493095 
    chicken
    (Gallus gallus)
    Aves CCDC1011 coiled-coil domain containing 101 81(n)
    94.54(a)
      424726  NM_001031298.1  NP_001026469.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    96(a)
    1 → many
    GL343287.1(1017241-1025451)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.19972 Transcribed sequence with weak similarity to protein more 81.41(n)    142020437 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.136562 Transcribed sequence with weak similarity to protein more 80.16(n)    BI867369.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Sgf291 CG30390-PA 54.74(n)
    53.14(a)
      37429  NM_166436.2  NP_726051.1 
    worm
    (Caenorhabditis elegans)
    Secernentea Y17G9B.81 Protein Y17G9B.8 46.56(n)
    39.29(a)
      177246  NM_068234.5  NP_500635.2 


    ENSEMBL Gene Tree for CCDC101 (if available)
    TreeFam Gene Tree for CCDC101 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CCDC101 gene
    LOC6130382  LOC3882422  
    5 SIMAP similar genes for CCDC101 using alignment to 3 protein entries:     SGF29_HUMAN (see all proteins):
    FLJ16124    RHBG    KIAA0101    SEC14L3    RRM2B

    CCDC101 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for CCDC101
    PGOHUM00000249032


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/785 SNPs in CCDC101 are shown (see all 785)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1876608851,2
    --28563630(+) TTCAGC/TCTCCA 1 -- us2k10--------
    rs1927887111,2
    C--28563667(+) CACCAC/TGCCCA 1 -- us2k10--------
    rs1446117991,2
    --28563760(+) CACCTC/TGGCCT 1 -- us2k10--------
    rs1176681521,2
    C,F--28563901(+) CTTCAT/AAAAAG 1 -- us2k11Minor allele frequency- A:0.05EA 120
    rs1151547631,2
    C,F--28563960(+) CTGACG/ACCCAC 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1840896651,2
    C--28564081(+) CTGAGC/GTTGGT 1 -- us2k10--------
    rs113640901,2
    C--28564147(-) AGTTCC/-TGGGC 1 -- us2k12Minor allele frequency- -:0.00NA 4
    rs1500632051,2
    C--28564331(+) GAAAC-/ATGTGAT 1 -- us2k10--------
    rs1873421161,2
    --28564450(+) TTGTAG/TGTTAT 1 -- us2k10--------
    rs1405913671,2
    --28564642(+) ACCCAA/GGCTGG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CCDC101 (28565236 - 28603111 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for CCDC101:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv509608CNV Insertion20534489
    nsv905689CNV Loss21882294
    nsv905694CNV Loss21882294
    nsv833180CNV Loss17160897
    nsv905690CNV Gain21882294
    dgv2664n71CNV Gain21882294
    nsv833182CNV Gain17160897
    nsv9416CNV Gain+Loss18304495
    dgv842e1CNV Complex17122850
    dgv843e1CNV Complex17122850

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 613374    OMIM disorders: --

    7 diseases for CCDC101:    About MalaCards
    diabetic macular edema    retinal degeneration    inflammatory bowel disease    retinitis
    acute lymphoblastic leukemia    lymphoblastic leukemia    leukemia

    1 disease from the University of Copenhagen DISEASES database for CCDC101:
    Diabetic macular edema

    CCDC101 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CCDC101
    Human Genome Epidemiology (HuGE) Navigator: CCDC101 (1 document)

    Export disorders for CCDC101 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CCDC101 gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with CCDC101)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation. (PubMed id 21685874)1, 2 Bian C.... Min J. (2011)
    2. Common variants at five new loci associated with earl y-onset inflammatory bowel disease. (PubMed id 19915574)1, 4 Imielinski M....McGovern D. (2009)
    3. Deregulated expression of a novel component of TFTC/S TAGA histone acetyltransferase complexes, rat SGF29, in hepatocellular carcinom a: possible implication for the oncogenic potential of c-Myc. (PubMed id 17334388)1, 3 Kurabe N....Tashiro F. (2007)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. GCN5 acetylates and regulates the stability of the onc oprotein E2A-PBX1 in acute lymphoblastic leukemia. (PubMed id 23044487)1 Holmlund T....Wallberg A.E. (2013)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. The tightly controlled deubiquitination activity of t he human SAGA complex differentially modifies distinct gene regulatory elements . (PubMed id 21746879)1 Lang G....Tora L. (2011)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 112869 HGNC: 25156 AceView: LOC112869 Ensembl:ENSG00000176476 euGenes: HUgn112869
    ECgene: CCDC101 H-InvDB: CCDC101

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CCDC101 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CCDC101 gene:
    Search GeneIP for patents involving CCDC101

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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