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Aliases for CCAT2 Gene

Subcategory (RNA class) for CCAT2 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for CCAT2 Gene

  • Colon Cancer Associated Transcript 2 (Non-Protein Coding) 2 3 5
  • Non-Coding RNA Involved In Cancer Predisposition 1 2 3
  • Long Intergenic Non-Protein Coding RNA 873 2 3
  • LINC00873 3
  • NCCP1 3

External Ids for CCAT2 Gene

Previous GeneCards Identifiers for CCAT2 Gene

  • GC08U901766

Summaries for CCAT2 Gene

GeneCards Summary for CCAT2 Gene

CCAT2 (Colon Cancer Associated Transcript 2 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with CCAT2 include Prostate Cancer Susceptibility.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCAT2 Gene

Genomics for CCAT2 Gene

Regulatory Elements for CCAT2 Gene

Enhancers for CCAT2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08F127396 1.4 FANTOM5 Ensembl ENCODE 0.8 -0.1 -123 7.1 ZNF133 ARID4B RAD21 RARA ZNF207 CREM HMG20B CEBPB MIER2 KAT8 CASC8 MYC CCAT2 GC08M127382
GH08F127393 1.4 FANTOM5 Ensembl ENCODE 0.4 -5.6 -5569 2.4 ZNF316 MAFF MAFG NFE2 EMSY MAFK CASC8 CCAT2 GC08M127382
GH08F127389 0.9 FANTOM5 Ensembl ENCODE 0.4 -8.7 -8739 3.3 TBP TAF1 JUN MAX CEBPB NR3C1 EP300 FOSL1 JUND STAT3 CASC8 MYC CCAT2 GC08M127382
GH08F127387 0.9 Ensembl ENCODE 0.4 -13.0 -12998 0.8 IKZF1 TBX21 SPI1 GC08M127382 CCAT2
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around CCAT2 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCAT2 Gene

Chromosome:
8
Start:
127,400,399 bp from pter
End:
127,402,150 bp from pter
Size:
1,752 bases
Orientation:
Plus strand

Genomic View for CCAT2 Gene

Genes around CCAT2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCAT2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCAT2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCAT2 Gene

Proteins for CCAT2 Gene

Post-translational modifications for CCAT2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for CCAT2 Gene

Domains & Families for CCAT2 Gene

Gene Families for CCAT2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCAT2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CCAT2 Gene

Function for CCAT2 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCAT2 Gene

Localization for CCAT2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CCAT2 Gene

Pathways & Interactions for CCAT2 Gene

SuperPathways for CCAT2 Gene

No Data Available

Interacting Proteins for CCAT2 Gene

Gene Ontology (GO) - Biological Process for CCAT2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCAT2 Gene

Transcripts for CCAT2 Gene

mRNA/cDNA for CCAT2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CCAT2 Gene

No ASD Table

Relevant External Links for CCAT2 Gene

GeneLoc Exon Structure for
CCAT2
ECgene alternative splicing isoforms for
CCAT2

Expression for CCAT2 Gene

NURSA nuclear receptor signaling pathways regulating expression of CCAT2 Gene:

CCAT2
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for CCAT2 Gene

Orthologs for CCAT2 Gene

Evolution for CCAT2 Gene

ENSEMBL:
Gene Tree for CCAT2 (if available)
TreeFam:
Gene Tree for CCAT2 (if available)

No data available for Orthologs for CCAT2 Gene

Paralogs for CCAT2 Gene

No data available for Paralogs for CCAT2 Gene

Variants for CCAT2 Gene

Sequence variations from dbSNP and Humsavar for CCAT2 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs10447996 -- 127,400,106(+) TTTCA(A/C)CCCTC intron-variant, upstream-variant-2KB
rs10505475 -- 127,399,212(-) GCAAC(A/C)TTTTC intron-variant, upstream-variant-2KB
rs10808556 -- 127,400,902(+) CTCCA(C/T)CTCTG intron-variant, nc-transcript-variant
rs113845658 -- 127,402,585(+) CTTAG(C/G)TAGAA intron-variant, downstream-variant-500B
rs114666053 -- 127,401,348(+) CCCAG(A/G)TAATA intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for CCAT2 Gene

Variant ID Type Subtype PubMed ID
nsv499795 OTHER inversion 21111241
nsv7419 OTHER inversion 18451855

Relevant External Links for CCAT2 Gene

Human Gene Mutation Database (HGMD)
CCAT2
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCAT2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CCAT2 Gene

Disorders for CCAT2 Gene

MalaCards: The human disease database

(1) MalaCards diseases for CCAT2 Gene - From: GeneCards

Disorder Aliases PubMed IDs
prostate cancer susceptibility
- elite association - COSMIC cancer census association via MalaCards
Search CCAT2 in MalaCards View complete list of genes associated with diseases

Relevant External Links for CCAT2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCAT2
genes like me logo Genes that share disorders with CCAT2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CCAT2 Gene

Publications for CCAT2 Gene

  1. CCAT2 is a lung adenocarcinoma-specific long non-coding RNA and promotes invasion of non-small cell lung cancer. (PMID: 24504682) Qiu M. … Yin R. (Tumour Biol. 2014) 2 3 64
  2. CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer. (PMID: 23796952) Ling H. … Calin G.A. (Genome Res. 2013) 2 3 64
  3. Roles of Long Non-Coding RNA CCAT2 in Cervical Cancer Cell Growth and Apoptosis. (PMID: 26983975) Wu L. … Zhang L. (Med. Sci. Monit. 2016) 3 64
  4. Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2. (PMID: 26853146) Redis R.S. … Calin G.A. (Mol. Cell 2016) 3 64
  5. Long noncoding RNA CCAT2 correlates with smoking in esophageal squamous cell carcinoma. (PMID: 25677908) Wang J. … Xu L. (Tumour Biol. 2015) 3 64

Products for CCAT2 Gene

Sources for CCAT2 Gene

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