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CCAT2 Gene(RNA Gene)

Colon Cancer Associated Transcript 2 (Non-Protein Coding)

GCID:
GC08P127400
GIFtS:
14
Genes Participants
UDN Logo

Aliases for CCAT2 Gene

Subcategory (RNA class) for CCAT2 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for CCAT2 Gene

  • Colon Cancer Associated Transcript 2 (Non-Protein Coding) 2 3 5
  • Non-Coding RNA Involved In Cancer Predisposition 1 2 3
  • Long Intergenic Non-Protein Coding RNA 873 2 3
  • LINC00873 3
  • NCCP1 3

External Ids for CCAT2 Gene

Previous GeneCards Identifiers for CCAT2 Gene

  • GC08U901766

Summaries for CCAT2 Gene

GeneCards Summary for CCAT2 Gene

CCAT2 (Colon Cancer Associated Transcript 2 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with CCAT2 include Prostate Cancer Susceptibility.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCAT2 Gene

Genomics for CCAT2 Gene

Products:

  1. Regulatory Element

Regulatory Elements for CCAT2 Gene

Enhancers for CCAT2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08G127396 1.5 FANTOM5 ENCODE dbSUPER 0.7 -0.1 -123 7.1 FOXA2 ZNF133 ARID4B BMI1 RAD21 RARA ZNF207 CREM HMG20B CEBPB CASC8 MYC CCAT2 GC08M127382
GH08G127389 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -8.7 -8739 3.3 TBP CTCF TAF1 JUN MAX CEBPB NR3C1 EP300 FOSL1 JUND CASC8 MYC CCAT2 GC08M127382
GH08G127393 1.1 FANTOM5 ENCODE dbSUPER 0.4 -5.6 -5569 2.4 MAFG ATF2 ZNF316 MAFF CREB1 NFE2 MAFK EMSY CASC8 CCAT2 GC08M127382
GH08G127387 0.5 ENCODE 0.4 -13.2 -13249 0.2 IKZF1 TBX21 SPI1 GC08M127382 CCAT2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CCAT2 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCAT2 Gene

Chromosome:
8
Start:
127,400,399 bp from pter
End:
127,402,150 bp from pter
Size:
1,752 bases
Orientation:
Plus strand

Genomic View for CCAT2 Gene

Genes around CCAT2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCAT2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCAT2 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for CCAT2 Gene

Proteins for CCAT2 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for CCAT2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for CCAT2 Gene

Domains & Families for CCAT2 Gene

Gene Families for CCAT2 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCAT2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CCAT2 Gene

Function for CCAT2 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Animal Model Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCAT2 Gene

Localization for CCAT2 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CCAT2 gene
Compartment Confidence
cytoskeleton 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCAT2 Gene

Pathways & Interactions for CCAT2 Gene

SuperPathways for CCAT2 Gene

PathCards logo More details on SuperPathways for CCAT2
No Data Available

Interacting Proteins for CCAT2 Gene

Gene Ontology (GO) - Biological Process for CCAT2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCAT2 Gene

Drugs & Compounds for CCAT2 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for CCAT2 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for CCAT2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCAT2 Gene

No ASD Table

Relevant External Links for CCAT2 Gene

GeneLoc Exon Structure for
CCAT2
ECgene alternative splicing isoforms for
CCAT2

Expression for CCAT2 Gene

Products:

  1. Primer

NURSA nuclear receptor signaling pathways regulating expression of CCAT2 Gene:

CCAT2
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCAT2 Gene

Orthologs for CCAT2 Gene

Evolution for CCAT2 Gene

ENSEMBL:
Gene Tree for CCAT2 (if available)
TreeFam:
Gene Tree for CCAT2 (if available)

No data available for Orthologs for CCAT2 Gene

Paralogs for CCAT2 Gene

No data available for Paralogs for CCAT2 Gene

Variants for CCAT2 Gene

Sequence variations from dbSNP and Humsavar for CCAT2 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1001628743 -- 127,400,050(+) GTTTA(A/G)AAGGC intron-variant, upstream-variant-2KB
rs1001681100 -- 127,400,361(+) CAGGG(C/T)CAAAT intron-variant, upstream-variant-2KB
rs1002119926 -- 127,402,526(+) ATCTG(G/T)CTCTG intron-variant, downstream-variant-500B
rs1003151845 -- 127,401,446(+) AAGGC(A/G)TTCTG intron-variant, nc-transcript-variant
rs1003296352 -- 127,401,674(+) AGTTC(A/C)TATTA intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for CCAT2 Gene

Variant ID Type Subtype PubMed ID
nsv499795 OTHER inversion 21111241
nsv7419 OTHER inversion 18451855

Relevant External Links for CCAT2 Gene

Human Gene Mutation Database (HGMD)
CCAT2
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCAT2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CCAT2 Gene

Disorders for CCAT2 Gene

MalaCards: The human disease database

(1) MalaCards diseases for CCAT2 Gene - From: GeneCards

Disorder Aliases PubMed IDs
prostate cancer susceptibility
- elite association - COSMIC cancer census association via MalaCards
Search CCAT2 in MalaCards View complete list of genes associated with diseases

Relevant External Links for CCAT2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCAT2
genes like me logo Genes that share disorders with CCAT2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CCAT2 Gene

Publications for CCAT2 Gene

  1. CCAT2 is a lung adenocarcinoma-specific long non-coding RNA and promotes invasion of non-small cell lung cancer. (PMID: 24504682) Qiu M. … Yin R. (Tumour Biol. 2014) 2 3 64
  2. CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer. (PMID: 23796952) Ling H. … Calin G.A. (Genome Res. 2013) 2 3 64
  3. The Expression of CCAT2, a Novel Long Noncoding RNA Transcript, and rs6983267 Single-Nucleotide Polymorphism Genotypes in Colorectal Cancers. (PMID: 27875818) Kasagi Y. … Maehara Y. (Oncology 2017) 3 64
  4. Long noncoding RNA CCAT2 can predict metastasis and poor prognosis: A meta-analysis. (PMID: 28089750) Fan Y.H. … Zhu X.G. (Clin. Chim. Acta 2017) 3 64
  5. LncRNA CCAT2 promotes tumorigenesis by over-expressed Pokemon in non-small cell lung cancer. (PMID: 28088736) Zhao Z. … Qu J. (Biomed. Pharmacother. 2017) 3 64

Products for CCAT2 Gene

Sources for CCAT2 Gene

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