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Aliases for CCAT1 Gene

Subcategory (RNA class) for CCAT1 Gene

non-coding RNA

Quality Score for this RNA gene is

2

Aliases for CCAT1 Gene

  • Colon Cancer Associated Transcript 1 (Non-Protein Coding) 2 3
  • Onco-LncRNA-40 3
  • CARLo-5 3

External Ids for CCAT1 Gene

Previous GeneCards Identifiers for CCAT1 Gene

  • GC08M128221

Summaries for CCAT1 Gene

GeneCards Summary for CCAT1 Gene

CCAT1 (Colon Cancer Associated Transcript 1 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for CCAT1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCAT1 Gene

Genomics for CCAT1 Gene

Regulatory Elements for CCAT1 Gene

Enhancers for CCAT1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08H126318 0.8 Ensembl 4.7 +900.4 900368 0 LEF1 NFRKB CEBPG ZBTB40 E2F1 MTA3 CTBP1 POLR2A NCOR1 TRIM24 CCAT1 LOC101927657 RFPL4AP5
GH08H127204 2 FANTOM5 Ensembl ENCODE dbSUPER 0.7 +2.6 2612 24 HDGF PKNOX1 FOXA2 MLX ARID4B SIN3A DMAP1 YBX1 YY1 SLC30A9 CCAT1 GC08P127149
GH08H127195 1.7 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +22.2 22235 3 HDGF TBL1XR1 RB1 BATF ZNF143 ATF7 RCOR1 ETV6 RUNX3 CREM CCAT1 GC08P127149
GH08H127183 1.4 FANTOM5 ENCODE dbSUPER 0.3 +34.6 34573 1 PKNOX1 TBL1XR1 EBF1 BATF RELA ATF7 ETV6 RUNX3 IKZF2 CREM GC08P127149 CCAT1
GH08H127178 1.1 ENCODE dbSUPER 0.3 +39.3 39313 2 HDGF PKNOX1 ATF1 TBL1XR1 RB1 YBX1 BATF RAD21 ZNF143 ATF7 GC08P127149 CCAT1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CCAT1 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCAT1 Gene

Chromosome:
8
Start:
127,207,382 bp from pter
End:
127,219,268 bp from pter
Size:
11,887 bases
Orientation:
Minus strand

Genomic View for CCAT1 Gene

Genes around CCAT1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCAT1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCAT1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCAT1 Gene

Proteins for CCAT1 Gene

Post-translational modifications for CCAT1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for CCAT1 Gene

Domains & Families for CCAT1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCAT1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CCAT1 Gene

Function for CCAT1 Gene

Phenotypes From GWAS Catalog for CCAT1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCAT1 Gene

Localization for CCAT1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CCAT1 Gene

Pathways & Interactions for CCAT1 Gene

SuperPathways for CCAT1 Gene

No Data Available

Interacting Proteins for CCAT1 Gene

Gene Ontology (GO) - Biological Process for CCAT1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCAT1 Gene

Drugs & Compounds for CCAT1 Gene

No Compound Related Data Available

Transcripts for CCAT1 Gene

mRNA/cDNA for CCAT1 Gene

(7) Additional mRNA sequences :

Unigene Clusters for CCAT1 Gene

Colon cancer associated transcript 1 (non-protein coding):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCAT1 Gene

No ASD Table

Relevant External Links for CCAT1 Gene

GeneLoc Exon Structure for
CCAT1
ECgene alternative splicing isoforms for
CCAT1

Expression for CCAT1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CCAT1 Gene

mRNA differential expression in normal tissues according to GTEx for CCAT1 Gene

This gene is overexpressed in Esophagus - Mucosa (x23.4) and Liver (x18.0).

NURSA nuclear receptor signaling pathways regulating expression of CCAT1 Gene:

CCAT1

SOURCE GeneReport for Unigene cluster for CCAT1 Gene:

Hs.343864
genes like me logo Genes that share expression patterns with CCAT1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCAT1 Gene

Orthologs for CCAT1 Gene

No data available for Orthologs and Evolution for CCAT1 Gene

Paralogs for CCAT1 Gene

No data available for Paralogs for CCAT1 Gene

Variants for CCAT1 Gene

Sequence variations from dbSNP and Humsavar for CCAT1 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1000111217 -- 127,215,519(+) ATAAG(G/T)GTGCC intron-variant
rs1000203645 -- 127,207,197(+) CCCAG(C/G)ACAGT downstream-variant-500B
rs1000575419 -- 127,207,460(+) TACAC(A/G)GTAGA nc-transcript-variant
rs1000694899 -- 127,209,582(+) GAAGA(C/T)GGATG nc-transcript-variant
rs1000962611 -- 127,214,662(+) ACCTC(C/T)AACAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCAT1 Gene

Variant ID Type Subtype PubMed ID
nsv499795 OTHER inversion 21111241
nsv7419 OTHER inversion 18451855
nsv831457 CNV gain 17160897

Relevant External Links for CCAT1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCAT1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CCAT1 Gene

Disorders for CCAT1 Gene

Relevant External Links for CCAT1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCAT1

No disorders were found for CCAT1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCAT1 Gene

Publications for CCAT1 Gene

  1. Long-range interaction and correlation between MYC enhancer and oncogenic long noncoding RNA CARLo-5. (PMID: 24594601) Kim T … Croce CM (Proceedings of the National Academy of Sciences of the United States of America 2014) 2 3 60
  2. Detection of a long non-coding RNA (CCAT1) in living cells and human adenocarcinoma of colon tissues using FIT-PNA molecular beacons. (PMID: 23416875) Kam Y … Yavin E (Cancer letters 2014) 2 3 60
  3. Long noncoding RNA CCAT1, which could be activated by c-Myc, promotes the progression of gastric carcinoma. (PMID: 23143645) Yang F … Fang G (Journal of cancer research and clinical oncology 2013) 2 3 60
  4. Colon cancer associated transcript-1: a novel RNA expressed in malignant and pre-malignant human tissues. (PMID: 21547902) Nissan A … Gure AO (International journal of cancer 2012) 2 3 60
  5. Long non-coding RNA CCAT1/miR-218/ZFX axis modulates the progression of laryngeal squamous cell cancer. (PMID: 28631575) Zhang Y … Hu H (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017) 3 60

Products for CCAT1 Gene

Sources for CCAT1 Gene

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