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Aliases for CCAT1 Gene

Subcategory (RNA class) for CCAT1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for CCAT1 Gene

  • Colon Cancer Associated Transcript 1 (Non-Protein Coding) 2 3 5
  • Onco-LncRNA-40 3
  • CARLo-5 3

External Ids for CCAT1 Gene

Previous GeneCards Identifiers for CCAT1 Gene

  • GC08M128221

Summaries for CCAT1 Gene

GeneCards Summary for CCAT1 Gene

CCAT1 (Colon Cancer Associated Transcript 1 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCAT1 Gene

Genomics for CCAT1 Gene

Regulatory Elements for CCAT1 Gene

Enhancers for CCAT1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08G126318 0.8 Ensembl 4.7 +900.4 900368 0.2 LEF1 CREB3L1 NFRKB CEBPG ZBTB40 E2F1 POLR2A NCOR1 TRIM24 L3MBTL2 CCAT1 LOC101927657 RFPL4AP5
GH08G127204 2 FANTOM5 Ensembl ENCODE dbSUPER 0.7 +2.6 2612 24.9 HDGF FOXA2 PKNOX1 MLX WRNIP1 ARID4B SIN3A DMAP1 YBX1 ZBTB7B CCAT1 CASC19
GH08G127241 0.9 FANTOM5 dbSUPER 0.3 -21.9 -21943 0.2 HDGF ZNF687 NFIB HLF SIN3A DPF2 ZNF592 NONO CTBP1 FOXK2 CASC21 CCAT1
GH08G127233 0.6 dbSUPER 0.4 -15.6 -15577 2.0 MTA2 CHD1 JUNB ATF2 ZKSCAN1 ARID3A FOXK2 MLLT1 CASC21 CCAT1
GH08G127239 0.8 dbSUPER 0.3 -20.5 -20497 1.4 PKNOX1 JUN MAX ZBTB7B FOSL1 ZFHX2 EGR1 FOSL2 FOS IKZF2 CASC21 CCAT1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CCAT1 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCAT1 Gene

Chromosome:
8
Start:
127,207,382 bp from pter
End:
127,219,268 bp from pter
Size:
11,887 bases
Orientation:
Minus strand

Genomic View for CCAT1 Gene

Genes around CCAT1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCAT1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCAT1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCAT1 Gene

Proteins for CCAT1 Gene

Post-translational modifications for CCAT1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for CCAT1 Gene

Domains & Families for CCAT1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCAT1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CCAT1 Gene

Function for CCAT1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCAT1 Gene

Localization for CCAT1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CCAT1 Gene

Pathways & Interactions for CCAT1 Gene

SuperPathways for CCAT1 Gene

No Data Available

Interacting Proteins for CCAT1 Gene

Gene Ontology (GO) - Biological Process for CCAT1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCAT1 Gene

Transcripts for CCAT1 Gene

mRNA/cDNA for CCAT1 Gene

(7) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCAT1 Gene

Colon cancer associated transcript 1 (non-protein coding):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCAT1 Gene

No ASD Table

Relevant External Links for CCAT1 Gene

GeneLoc Exon Structure for
CCAT1
ECgene alternative splicing isoforms for
CCAT1

Expression for CCAT1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CCAT1 Gene

mRNA differential expression in normal tissues according to GTEx for CCAT1 Gene

This gene is overexpressed in Esophagus - Mucosa (x23.4) and Liver (x18.0).

NURSA nuclear receptor signaling pathways regulating expression of CCAT1 Gene:

CCAT1

SOURCE GeneReport for Unigene cluster for CCAT1 Gene:

Hs.343864
genes like me logo Genes that share expression patterns with CCAT1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCAT1 Gene

Orthologs for CCAT1 Gene

Evolution for CCAT1 Gene

ENSEMBL:
Gene Tree for CCAT1 (if available)
TreeFam:
Gene Tree for CCAT1 (if available)

No data available for Orthologs for CCAT1 Gene

Paralogs for CCAT1 Gene

No data available for Paralogs for CCAT1 Gene

Variants for CCAT1 Gene

Sequence variations from dbSNP and Humsavar for CCAT1 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1000111217 -- 127,215,519(+) ATAAG(G/T)GTGCC intron-variant
rs1000203645 -- 127,207,197(+) CCCAG(C/G)ACAGT downstream-variant-500B
rs1000575419 -- 127,207,460(+) TACAC(A/G)GTAGA nc-transcript-variant
rs1000694899 -- 127,209,582(+) GAAGA(C/T)GGATG nc-transcript-variant
rs1000962611 -- 127,214,662(+) ACCTC(C/T)AACAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCAT1 Gene

Variant ID Type Subtype PubMed ID
nsv499795 OTHER inversion 21111241
nsv7419 OTHER inversion 18451855
nsv831457 CNV gain 17160897

Relevant External Links for CCAT1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCAT1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CCAT1 Gene

Disorders for CCAT1 Gene

Relevant External Links for CCAT1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCAT1

No disorders were found for CCAT1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCAT1 Gene

Publications for CCAT1 Gene

  1. Long-range interaction and correlation between MYC enhancer and oncogenic long noncoding RNA CARLo-5. (PMID: 24594601) Kim T. … Croce C.M. (Proc. Natl. Acad. Sci. U.S.A. 2014) 2 3 64
  2. Long noncoding RNA CCAT1, which could be activated by c-Myc, promotes the progression of gastric carcinoma. (PMID: 23143645) Yang F. … Fang G. (J. Cancer Res. Clin. Oncol. 2013) 2 3 64
  3. Detection of a long non-coding RNA (CCAT1) in living cells and human adenocarcinoma of colon tissues using FIT-PNA molecular beacons. (PMID: 23416875) Kam Y. … Yavin E. (Cancer Lett. 2013) 2 3 64
  4. Colon cancer associated transcript-1: a novel RNA expressed in malignant and pre-malignant human tissues. (PMID: 21547902) Nissan A. … Gure A.O. (Int. J. Cancer 2012) 2 3 64
  5. CCAT1: an oncogenic long noncoding RNA in human cancers. (PMID: 27638771) Guo X. … Hua Y. (J. Cancer Res. Clin. Oncol. 2017) 3 64

Products for CCAT1 Gene

Sources for CCAT1 Gene

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