Aliases for CCAR1 Gene
Aliases for CCAR1 Gene
External Ids for CCAR1 Gene
- HGNC: 24236
- Entrez Gene: 55749
- Ensembl: ENSG00000060339
- OMIM: 612569
- UniProtKB: Q8IX12
Previous GeneCards Identifiers for CCAR1 Gene
- GC10P069826
- GC10P070150
- GC10P070480
- GC10P064482
Summaries for CCAR1 Gene
GeneCards Summary for CCAR1 Gene
CCAR1 (Cell Division Cycle And Apoptosis Regulator 1) is a Protein Coding gene. Diseases associated with CCAR1 include Dissociative Amnesia and Multiple Personality Disorder. Among its related pathways are Gene Expression and mRNA Splicing - Major Pathway. GO annotations related to this gene include nucleic acid binding and ligand-dependent nuclear receptor transcription coactivator activity. An important paralog of this gene is CCAR2.
UniProtKB/Swiss-Prot for CCAR1 Gene
-
Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation (PubMed:12816952). In association with CALCOCO1 enhances GATA1- and MED1-mediated transcriptional activation from the gamma-globin promoter during erythroid differentiation of K562 erythroleukemia cells (PubMed:24245781). Can act as a both a coactivator and corepressor of AR-mediated transcription. Contributes to chromatin looping and AR transcription complex assembly by stabilizing AR-GATA2 association on chromatin and facilitating MED1 and RNA polymerase II recruitment to AR-binding sites. May play an important role in the growth and tumorigenesis of prostate cancer cells (PubMed:23887938).
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCAR1 Gene
Genomics for CCAR1 Gene
Regulatory Elements for CCAR1 Gene
Enhancers for CCAR1 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CCAR1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for CCAR1 Gene
- Chromosome:
- 10
- Start:
- 68,721,012 bp from pter
- End:
- 68,792,377 bp from pter
- Size:
- 71,366 bases
- Orientation:
- Plus strand
Genomic View for CCAR1 Gene
Genes around CCAR1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 10q21.3 by Ensembl
- 10q21.3 by Entrez Gene
- 10q21.3 by HGNC
CCAR1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CCAR1 Gene
Proteins for CCAR1 Gene
-
Protein details for CCAR1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8IX12-CCAR1_HUMAN
- Recommended name:
- Cell division cycle and apoptosis regulator protein 1
- Protein Accession:
- Q8IX12
- A0JLT7
- A1L4P7
- A8K9D4
- B4DNP8
- B4DRK8
- Q32NE3
- Q5EBM3
- Q5VUP6
- Q6PIZ0
- Q6X935
- Q9H8N4
- Q9NVA7
- Q9NVQ0
- Q9NWM6
Protein attributes for CCAR1 Gene
- Size:
- 1150 amino acids
- Molecular mass:
- 132821 Da
- Quaternary structure:
-
- Directly interacts with ESR1, NR3C1 and p53/TP53 (By similarity). Interacts (via N-terminus) with CALCOCO1. Interacts with MED1 (By similarity). Interacts with GATA1. Interacts with AR and GATA2.
- SequenceCaution:
-
- Sequence=AAH26036.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=AAI08683.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=BAA91354.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for CCAR1 Gene
Post-translational modifications for CCAR1 Gene
Other Protein References for CCAR1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for CCAR1
- Invitrogen Antibodies for CCAR1
- antibodies-online Antibodies for CCAR1: See all 44
- GeneTex CCAR1 antibody for CCAR1
-
Santa Cruz Biotechnology (SCBT) Antibodies for CCAR1
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for CCAR1
- Origene Custom Protein Services for CCAR1
- Novus Biologicals proteins for CCAR1
- Search GeneTex for Proteins for CCAR1
Assay Products
- antibodies-online Kits for CCAR1: See all 3
No data available for DME Specific Peptides for CCAR1 Gene
Domains & Families for CCAR1 Gene
Protein Domains for CCAR1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CCAR1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families and UniProtKB/Swiss-Prot for CCAR1 Gene
Function for CCAR1 Gene
Molecular function for CCAR1 Gene
- UniProtKB/Swiss-Prot Function:
- Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation (PubMed:12816952). In association with CALCOCO1 enhances GATA1- and MED1-mediated transcriptional activation from the gamma-globin promoter during erythroid differentiation of K562 erythroleukemia cells (PubMed:24245781). Can act as a both a coactivator and corepressor of AR-mediated transcription. Contributes to chromatin looping and AR transcription complex assembly by stabilizing AR-GATA2 association on chromatin and facilitating MED1 and RNA polymerase II recruitment to AR-binding sites. May play an important role in the growth and tumorigenesis of prostate cancer cells (PubMed:23887938).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001047 | core promoter binding | IDA | 24245781 |
| GO:0003713 | transcription coactivator activity | IMP | 23887938 |
| GO:0003714 | transcription corepressor activity | IMP | 23887938 |
| GO:0003723 | RNA binding | IDA | 22658674 |
| GO:0005515 | protein binding | IPI | 18157088 |
Phenotypes for CCAR1 Gene
- GenomeRNAi human phenotypes for CCAR1:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CCAR1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CCAR1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CCAR1 gene
- Search ViGene Biosciences for CCAR1
CRISPR Products
-
OriGene CRISPR knockouts for CCAR1
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCAR1
- GenScript: Design CRISPR guide RNA sequences for CCAR1
miRNA for CCAR1 Gene
- miRTarBase miRNAs that target CCAR1
miRNA Products
- Search ViGene Biosciences for CCAR1
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CCAR1
- Browse OriGene Inhibitory RNA Products For CCAR1
-
ViGene Biosciences ready-to-package AAV shRNAs for CCAR1 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CCAR1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCAR1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CCAR1
-
ViGene Biosciences adenoviral particle packaged cDNA for CCAR1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CCAR1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CCAR1 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCAR1 Gene
Localization for CCAR1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CCAR1 Gene
- Cytoplasm, perinuclear region.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| mitochondrion | 2 |
| cytosol | 2 |
| golgi apparatus | 2 |
| extracellular | 1 |
| cytoskeleton | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0048471 | perinuclear region of cytoplasm | IEA | -- |
Pathways & Interactions for CCAR1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | mRNA Splicing - Major Pathway |
.79
|
|
| 2 | Gene Expression |
.48
|
|
Pathways by source for CCAR1 Gene
4 Reactome pathways for CCAR1 Gene
Interacting Proteins for CCAR1 Gene
Selected Interacting proteins:
Q8IX12-CCAR1_HUMAN
ENSP00000265872
for CCAR1 Gene via
IID
STRING
UniProtKB
MINT
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000398 | mRNA splicing, via spliceosome | TAS | -- |
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006915 | apoptotic process | IEA | -- |
| GO:0007049 | cell cycle | IEA | -- |
No data available for SIGNOR curated interactions for CCAR1 Gene
Transcripts for CCAR1 Gene
mRNA/cDNA for CCAR1 Gene
- (3) REFSEQ mRNAs :
- (23) Additional mRNA sequences :
- (224) Selected AceView cDNA sequences:
- (18) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CCAR1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for CCAR1
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCAR1
- GenScript: Design CRISPR guide RNA sequences for CCAR1
miRNA Products
- Search ViGene Biosciences for CCAR1
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CCAR1
- Browse OriGene Inhibitory RNA Products For CCAR1
-
ViGene Biosciences ready-to-package AAV shRNAs for CCAR1 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CCAR1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCAR1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20a | · | 20b | ^ | 21 | ^ | 22a | · | 22b | · | 22c | ^ | 23a | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: |
| ExUns: | 23b | ^ | 24a | · | 24b | ^ | 25a | · | 25b | ^ | 26a | · | 26b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||
| SP2: | |||||||||||||
| SP3: | |||||||||||||
| SP4: | - | ||||||||||||
| SP5: | - | ||||||||||||
| SP6: | |||||||||||||
| SP7: | |||||||||||||
| SP8: | |||||||||||||
| SP9: | |||||||||||||
| SP10: | - | ||||||||||||
| SP11: |
Expression for CCAR1 Gene
This gene is overexpressed in Lymph node (11.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CCAR1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of CCAR1 Gene:
CCAR1SOURCE GeneReport for Unigene cluster for CCAR1 Gene:
Hs.49853mRNA Expression by UniProt/SwissProt for CCAR1 Gene:
Q8IX12-CCAR1_HUMAN
Tissue specificity:
Expressed in various epithelial cancer cell lines, including breast, colon, prostate, pancreatic and leukemia. Expression is regulated by growth factors.
Evidence on tissue expression from TISSUES for CCAR1 Gene
- Nervous system(4.9)
- Lung(4.5)
- Muscle(4.5)
- Liver(4.4)
- Skin(4.4)
- Heart(2.6)
- Blood(2.5)
- Intestine(2.4)
- Kidney(2.3)
Primer Products
-
OriGene qPCR primer pairs for CCAR1
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCAR1 Gene
Orthologs for CCAR1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CCAR1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | -- 35 |
|
OneToMany | |
| CCAR1 34 35 |
|
||||
| dog (Canis familiaris) |
Mammalia | CCAR1 34 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | CCAR1 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| mouse (Mus musculus) |
Mammalia | Ccar1 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ccar1 34 |
|
||
| chicken (Gallus gallus) |
Aves | CCAR1 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | CCAR1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | ccar1 34 |
|
||
| Str.7672 34 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.30247 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | ccar1 35 |
|
OneToOne | |
| LOC568087 34 |
|
||||
| worm (Caenorhabditis elegans) |
Secernentea | lst-3 35 |
|
OneToMany |
- Species where no ortholog for CCAR1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for CCAR1 Gene
(1) SIMAP similar genes for CCAR1 Gene using alignment to 10 proteins:
Variants for CCAR1 Gene
| SNP ID | Clin | Chr 10 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| VAR_035497 | A colorectal cancer sample | ||||
| rs1000119523 | -- | 68,719,425(+) | CAGAA(A/G)TGTTA | upstream-variant-2KB | |
| rs1000159818 | -- | 68,734,094(+) | GAAAT(C/T)AGACT | intron-variant | |
| rs1000168421 | -- | 68,747,893(+) | CTGTC(A/G)CCCAG | intron-variant | |
| rs1000236303 | -- | 68,740,012(+) | TGTGG(C/T)CCTTC | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv919n100 | CNV | gain | 25217958 |
| esv2759764 | CNV | loss | 17122850 |
| esv3406931 | CNV | insertion | 20981092 |
| esv3546462 | CNV | deletion | 23714750 |
| nsv1047983 | CNV | gain | 25217958 |
| nsv1052569 | CNV | gain | 25217958 |
| nsv1134023 | CNV | deletion | 24896259 |
| nsv1144498 | CNV | deletion | 24896259 |
| nsv551435 | CNV | loss | 21841781 |
| nsv6999 | CNV | insertion | 18451855 |
| nsv8684 | CNV | gain | 18304495 |
Residual Variation Intolerance Score:
7.52% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.57;
44.66% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CCAR1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CCAR1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCAR1 Gene
Disorders for CCAR1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| dissociative amnesia |
|
|
| multiple personality disorder |
|
|
Search CCAR1 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for CCAR1
No data available for UniProtKB/Swiss-Prot and Genatlas for CCAR1 Gene
Publications for CCAR1 Gene
- Identification and characterization of a cell cycle and apoptosis regulatory protein-1 as a novel mediator of apoptosis signaling by retinoid CD437. (PMID: 12816952) Rishi A.K. … Reichert U. (J. Biol. Chem. 2003) 2 3 4 64
- CCAR1/CoCoA pair-mediated recruitment of the Mediator defines a novel pathway for GATA1 function. (PMID: 24245781) Mizuta S. … Ito M. (Genes Cells 2014) 3 4 64
- CCAR1 promotes chromatin loading of androgen receptor (AR) transcription complex by stabilizing the association between AR and GATA2. (PMID: 23887938) Seo W.Y. … Kim J.H. (Nucleic Acids Res. 2013) 3 4 64
- CCAR1, a key regulator of mediator complex recruitment to nuclear receptor transcription complexes. (PMID: 18722177) Kim J.H. … Stallcup M.R. (Mol. Cell 2008) 3 4 64
- A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PMID: 16385451) Grupe A. … Goate A. (Am. J. Hum. Genet. 2006) 3 46 64
Products for CCAR1 Gene
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- Novus Biologicals Antibodies for CCAR1
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- antibodies-online Antibodies for CCAR1: See all 44
- antibodies-online Kits for CCAR1: See all 3
- Search antibodies-online for proteins
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- GeneTex CCAR1 antibody for CCAR1
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- ViGene Biosciences adenoviral particle packaged cDNA for CCAR1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CCAR1 gene
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- Search ViGene Biosciences for CCAR1
- Santa Cruz Biotechnology (SCBT) Antibodies for CCAR1
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- Horizon Cell Lines for CCAR1
- Cyagen custom Knockout/knockin (KOKI) mouse models for CCAR1
- VectorBuilder custom plasmid, inducible vectors for CCAR1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCAR1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CCAR1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
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