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Aliases for CC2D2B Gene

Aliases for CC2D2B Gene

  • Coiled-Coil And C2 Domain Containing 2B 2 3
  • C10orf130 3 4
  • Chromosome 10 Open Reading Frame 130 2
  • Protein CC2D2B 3
  • BA248J23.4 3

External Ids for CC2D2B Gene

Previous HGNC Symbols for CC2D2B Gene

  • C10orf130

Previous GeneCards Identifiers for CC2D2B Gene

  • GC10P097725
  • GC10P097751
  • GC10P097709
  • GC10P091387
  • GC10P097735

Summaries for CC2D2B Gene

GeneCards Summary for CC2D2B Gene

CC2D2B (Coiled-Coil And C2 Domain Containing 2B) is a Protein Coding gene. Diseases associated with CC2D2B include alcohol dependence and nephronophthisis. An important paralog of this gene is C10orf131.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CC2D2B Gene

Genomics for CC2D2B Gene

Regulatory Elements for CC2D2B Gene

Genomic Location for CC2D2B Gene

95,938,103 bp from pter
96,033,739 bp from pter
95,637 bases
Plus strand

Genomic View for CC2D2B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CC2D2B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CC2D2B Gene

Proteins for CC2D2B Gene

  • Protein details for CC2D2B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein CC2D2B
    Protein Accession:
    Secondary Accessions:
    • A2A3E9
    • B4DYD4
    • E9PCC3
    • Q5VUS0

    Protein attributes for CC2D2B Gene

    322 amino acids
    Molecular mass:
    37073 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CC2D2B Gene


neXtProt entry for CC2D2B Gene

Proteomics data for CC2D2B Gene at MOPED

Post-translational modifications for CC2D2B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CC2D2B Gene

No data available for DME Specific Peptides for CC2D2B Gene

Domains for CC2D2B Gene

Protein Domains for CC2D2B Gene


Suggested Antigen Peptide Sequences for CC2D2B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CC2D2B: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CC2D2B Gene

Function for CC2D2B Gene

Animal Model Products

CRISPR Products

miRNA for CC2D2B Gene

miRTarBase miRNAs that target CC2D2B

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CC2D2B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for CC2D2B Gene

Localization for CC2D2B Gene

Subcellular locations from

Jensen Localization Image for CC2D2B Gene COMPARTMENTS Subcellular localization image for CC2D2B gene
Compartment Confidence
cytosol 2
nucleus 2
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CC2D2B Gene

Pathways for CC2D2B Gene

SuperPathways for CC2D2B Gene

No Data Available

Interacting Proteins for CC2D2B Gene

Gene Ontology (GO) - Biological Process for CC2D2B Gene


No data available for Pathways by source for CC2D2B Gene

Transcripts for CC2D2B Gene

mRNA/cDNA for CC2D2B Gene

(9) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(11) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CC2D2B Gene

Coiled-coil and C2 domain containing 2B:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CC2D2B

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CC2D2B Gene

No ASD Table

Relevant External Links for CC2D2B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CC2D2B Gene

mRNA expression in normal human tissues for CC2D2B Gene

mRNA differential expression in normal tissues according to GTEx for CC2D2B Gene

This gene is overexpressed in Testis (9.0).

SOURCE GeneReport for Unigene cluster for CC2D2B Gene Hs.652240

genes like me logo Genes that share expressions with CC2D2B: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for CC2D2B Gene

Orthologs for CC2D2B Gene

This gene was present in the common ancestor of animals.

Orthologs for CC2D2B Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia CC2D2B 35
  • 89.03 (n)
  • 84.04 (a)
(Pan troglodytes)
Mammalia CC2D2B 35
  • 99.75 (n)
  • 99.25 (a)
-- 36
  • 99 (a)
(Mus musculus)
Mammalia Cc2d2b 16
(Monodelphis domestica)
Mammalia -- 36
  • 13 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 58 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 15 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG43370 36
  • 6 (a)
(Caenorhabditis elegans)
Secernentea mks-6 36
  • 7 (a)
Species with no ortholog for CC2D2B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for CC2D2B Gene

Gene Tree for CC2D2B (if available)
Gene Tree for CC2D2B (if available)

Paralogs for CC2D2B Gene

Paralogs for CC2D2B Gene

(1) SIMAP similar genes for CC2D2B Gene using alignment to 6 proteins: Pseudogenes for CC2D2B Gene

genes like me logo Genes that share paralogs with CC2D2B: view

Variants for CC2D2B Gene

Sequence variations from dbSNP and Humsavar for CC2D2B Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
VAR_050697 -
VAR_050698 -
VAR_050699 -

Relevant External Links for CC2D2B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CC2D2B Gene

Disorders for CC2D2B Gene

(2) University of Copenhagen DISEASES for CC2D2B Gene

Relevant External Links for CC2D2B

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with CC2D2B: view

No data available for OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships and Genatlas for CC2D2B Gene

Publications for CC2D2B Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PMID: 16385451) Grupe A. … Goate A. (Am. J. Hum. Genet. 2006) 3 48
  5. A genome-wide association study of alcohol dependence. (PMID: 20202923) Bierut L.J. … Rice J.P. (Proc. Natl. Acad. Sci. U.S.A. 2010) 48

Products for CC2D2B Gene

Sources for CC2D2B Gene

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