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Aliases for CBY3 Gene

Aliases for CBY3 Gene

  • Chibby Homolog 3 (Drosophila) 2 3 5

External Ids for CBY3 Gene

Previous GeneCards Identifiers for CBY3 Gene

  • GC05M179041
  • GC00U922289
  • GC05M179042
  • GC05M179106
  • GC05M173832

Summaries for CBY3 Gene

GeneCards Summary for CBY3 Gene

CBY3 (Chibby Homolog 3 (Drosophila)) is a Protein Coding gene. An important paralog of this gene is CBY1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CBY3 Gene

Genomics for CBY3 Gene

Regulatory Elements for CBY3 Gene

Genomic Location for CBY3 Gene

Chromosome:
5
Start:
179,678,558 bp from pter
End:
179,680,974 bp from pter
Size:
2,417 bases
Orientation:
Minus strand

Genomic View for CBY3 Gene

Genes around CBY3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CBY3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CBY3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CBY3 Gene

Proteins for CBY3 Gene

  • Protein details for CBY3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NI87-CBY3_HUMAN
    Recommended name:
    Protein chibby homolog 3
    Protein Accession:
    A6NI87

    Protein attributes for CBY3 Gene

    Size:
    242 amino acids
    Molecular mass:
    27343 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • Chibby is Japanese for small; the gene was so named for the RNAi phenotype seen in flies.

neXtProt entry for CBY3 Gene

Proteomics data for CBY3 Gene at MOPED

Post-translational modifications for CBY3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CBY3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CBY3 Gene

Domains & Families for CBY3 Gene

Protein Domains for CBY3 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CBY3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NI87

UniProtKB/Swiss-Prot:

CBY3_HUMAN :
  • Belongs to the chibby family.
Family:
  • Belongs to the chibby family.
genes like me logo Genes that share domains with CBY3: view

No data available for Gene Families for CBY3 Gene

Function for CBY3 Gene

Phenotypes for CBY3 Gene

GenomeRNAi human phenotypes for CBY3:
genes like me logo Genes that share phenotypes with CBY3: view

Animal Model Products

miRNA for CBY3 Gene

miRTarBase miRNAs that target CBY3

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CBY3 Gene

Localization for CBY3 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CBY3 Gene COMPARTMENTS Subcellular localization image for CBY3 gene
Compartment Confidence
nucleus 3
cytosol 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CBY3 Gene

Pathways & Interactions for CBY3 Gene

SuperPathways for CBY3 Gene

No Data Available

Interacting Proteins for CBY3 Gene

Gene Ontology (GO) - Biological Process for CBY3 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CBY3 Gene

Drugs & Compounds for CBY3 Gene

No Compound Related Data Available

Transcripts for CBY3 Gene

mRNA/cDNA for CBY3 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CBY3 Gene

Chibby homolog 3 (Drosophila):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CBY3 Gene

No ASD Table

Relevant External Links for CBY3 Gene

GeneLoc Exon Structure for
CBY3
ECgene alternative splicing isoforms for
CBY3

Expression for CBY3 Gene

mRNA expression in normal human tissues for CBY3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CBY3 Gene

This gene is overexpressed in Testis (x24.0).

SOURCE GeneReport for Unigene cluster for CBY3 Gene Hs.535767

genes like me logo Genes that share expression patterns with CBY3: view

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CBY3 Gene

Orthologs for CBY3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CBY3 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia CBY3 35
  • 76.81 (n)
  • 61.3 (a)
CBY3 36
  • 58 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CBY3 36
  • 62 (a)
OneToOne
CBY3 35
  • 82.95 (n)
  • 69.12 (a)
mouse
(Mus musculus)
Mammalia Cby3 16
Cby3 36
  • 53 (a)
OneToOne
Cby3 35
  • 74.47 (n)
  • 63.9 (a)
oppossum
(Monodelphis domestica)
Mammalia CBY3 36
  • 52 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CBY3 36
  • 47 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Cby3 35
  • 72.12 (n)
  • 61.06 (a)
lizard
(Anolis carolinensis)
Reptilia CBY3 36
  • 48 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii cby1 36
  • 35 (a)
OneToMany
Species with no ortholog for CBY3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CBY3 Gene

ENSEMBL:
Gene Tree for CBY3 (if available)
TreeFam:
Gene Tree for CBY3 (if available)

Paralogs for CBY3 Gene

Paralogs for CBY3 Gene

(1) SIMAP similar genes for CBY3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CBY3: view

Variants for CBY3 Gene

Structural Variations from Database of Genomic Variants (DGV) for CBY3 Gene

Variant ID Type Subtype PubMed ID
nsv883270 CNV Loss 21882294
nsv7375 OTHER Inversion 18451855
nsv830560 CNV Loss 17160897
nsv282 OTHER Inversion 15895083
nsv5160 CNV Insertion 18451855

Variation tolerance for CBY3 Gene

Gene Damage Index Score: 3.77; 57.98% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CBY3 Gene

HapMap Linkage Disequilibrium report
CBY3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for CBY3 Gene

Disorders for CBY3 Gene

Relevant External Links for CBY3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CBY3

No disorders were found for CBY3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CBY3 Gene

Publications for CBY3 Gene

  1. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J. … Rubin E.M. (Nature 2004) 3 4 67

Products for CBY3 Gene

Sources for CBY3 Gene

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