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Aliases for CBY3 Gene

Aliases for CBY3 Gene

  • Chibby Homolog 3 (Drosophila) 2 3

External Ids for CBY3 Gene

Previous GeneCards Identifiers for CBY3 Gene

  • GC05M179041
  • GC00U922289
  • GC05M179042
  • GC05M179106
  • GC05M173832

Summaries for CBY3 Gene

GeneCards Summary for CBY3 Gene

CBY3 (Chibby Homolog 3 (Drosophila)) is a Protein Coding gene. An important paralog of this gene is CBY1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CBY3 Gene

Genomics for CBY3 Gene

Regulatory Elements for CBY3 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for CBY3 Gene

179,678,558 bp from pter
179,681,378 bp from pter
2,821 bases
Minus strand

Genomic View for CBY3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CBY3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CBY3 Gene

Proteins for CBY3 Gene

  • Protein details for CBY3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein chibby homolog 3
    Protein Accession:
    Secondary Accessions:

    Protein attributes for CBY3 Gene

    242 amino acids
    Molecular mass:
    27343 Da
    Quaternary structure:
    No Data Available
    • Chibby is Japanese for small; the gene was so named for the RNAi phenotype seen in flies

neXtProt entry for CBY3 Gene

Proteomics data for CBY3 Gene at MOPED

Post-translational modifications for CBY3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CBY3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CBY3 Gene

Domains for CBY3 Gene

Protein Domains for CBY3 Gene


Suggested Antigen Peptide Sequences for CBY3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • A6NI87
  • Belongs to the chibby family.
genes like me logo Genes that share domains with CBY3: view

No data available for Gene Families for CBY3 Gene

Function for CBY3 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CBY3 Gene

Localization for CBY3 Gene

Subcellular locations from

Jensen Localization Image for CBY3 Gene COMPARTMENTS Subcellular localization image for CBY3 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CBY3 Gene

Pathways for CBY3 Gene

SuperPathways for CBY3 Gene

No Data Available

Interacting Proteins for CBY3 Gene

Gene Ontology (GO) - Biological Process for CBY3 Gene


No data available for Pathways by source for CBY3 Gene

Transcripts for CBY3 Gene

mRNA/cDNA for CBY3 Gene

(0) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CBY3 Gene

Chibby homolog 3 (Drosophila):
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CBY3

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CBY3 Gene

No ASD Table

Relevant External Links for CBY3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CBY3 Gene

mRNA expression in normal human tissues for CBY3 Gene

mRNA differential expression in normal tissues according to GTEx for CBY3 Gene

This gene is overexpressed in Testis (24.0).

SOURCE GeneReport for Unigene cluster for CBY3 Gene Hs.535767

genes like me logo Genes that share expressions with CBY3: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for CBY3 Gene

Orthologs for CBY3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CBY3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CBY3 35
  • 76.81 (n)
  • 61.3 (a)
CBY3 36
  • 58 (a)
(Canis familiaris)
Mammalia CBY3 35
  • 82.95 (n)
  • 69.12 (a)
CBY3 36
  • 62 (a)
(Mus musculus)
Mammalia Cby3 35
  • 74.47 (n)
  • 63.9 (a)
Cby3 36
  • 53 (a)
(Monodelphis domestica)
Mammalia CBY3 36
  • 52 (a)
(Ornithorhynchus anatinus)
Mammalia CBY3 36
  • 47 (a)
(Rattus norvegicus)
Mammalia Cby3 35
  • 72.12 (n)
  • 61.06 (a)
(Anolis carolinensis)
Reptilia CBY3 36
  • 48 (a)
(Danio rerio)
Actinopterygii cby1 36
  • 35 (a)
Species with no ortholog for CBY3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CBY3 Gene

Gene Tree for CBY3 (if available)
Gene Tree for CBY3 (if available)

Paralogs for CBY3 Gene

Paralogs for CBY3 Gene

Selected SIMAP similar genes for CBY3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CBY3: view

Variants for CBY3 Gene

Sequence variations from dbSNP and Humsavar for CBY3 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs6879412 -- 179,681,976(+) caggc(A/G)cgatg upstream-variant-2KB
rs6880839 -- 179,679,330(+) AGGCC(A/G)GCGGA intron-variant
rs7443139 -- 179,682,659(+) tagcc(A/G)agatc upstream-variant-2KB
rs9763971 -- 179,682,403(+) aaccc(C/T)gtctc upstream-variant-2KB
rs10053812 -- 179,682,944(+) TGCCA(C/T)GTGTG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for CBY3 Gene

Variant ID Type Subtype PubMed ID
nsv883270 CNV Loss 21882294
nsv7375 OTHER Inversion 18451855
nsv830560 CNV Loss 17160897
nsv282 OTHER Inversion 15895083
nsv5160 CNV Insertion 18451855

Relevant External Links for CBY3 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CBY3 Gene

Disorders for CBY3 Gene

No disorders were found for CBY3 Gene.

No data available for UniProtKB/Swiss-Prot for CBY3 Gene

Publications for CBY3 Gene

  1. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J. … Rubin E.M. (Nature 2004) 3 4

Products for CBY3 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate CBY3
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat
  • Predesigned siRNA for gene silencing in human,mouse,rat for CBY3
  • Block miRNA regulation of CBY3 using miScript Target Protectors

Sources for CBY3 Gene

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