Aliases for CBY3 Gene
External Ids for CBY3 Gene
- HGNC: 33278
- Entrez Gene: 646019
- Ensembl: ENSG00000204659
- UniProtKB: A6NI87
Previous GeneCards Identifiers for CBY3 Gene
- GC05M179041
- GC00U922289
- GC05M179042
- GC05M179106
- GC05M173832
Summaries for CBY3 Gene
GeneCards Summary for CBY3 Gene
CBY3 (Chibby Family Member 3) is a Protein Coding gene. An important paralog of this gene is CBY1.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CBY3 Gene
Genomics for CBY3 Gene
Regulatory Elements for CBY3 Gene
Enhancers for CBY3 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CBY3 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the CBY3 gene promoter:
Regulatory Element Products
Genomic Location for CBY3 Gene
- Chromosome:
- 5
- Start:
- 179,678,558 bp from pter
- End:
- 179,680,974 bp from pter
- Size:
- 2,417 bases
- Orientation:
- Minus strand
Genomic View for CBY3 Gene
Genes around CBY3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 5q35.3 by Ensembl
- 5q35.3 by Entrez Gene
- 5q35.3 by HGNC
CBY3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CBY3 Gene
Proteins for CBY3 Gene
-
Protein details for CBY3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- A6NI87-CBY3_HUMAN
- Recommended name:
- Protein chibby homolog 3
- Protein Accession:
- A6NI87
Protein attributes for CBY3 Gene
- Size:
- 242 amino acids
- Molecular mass:
- 27343 Da
- Quaternary structure:
- No Data Available
- Miscellaneous:
-
- Chibby is Japanese for small; the gene was so named for the RNAi phenotype seen in flies.
Post-translational modifications for CBY3 Gene
Other Protein References for CBY3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for CBY3
- Invitrogen Antibodies for CBY3
- Search GeneTex for Antibodies for CBY3
Protein Products
-
OriGene Purified Proteins for CBY3
- Search Origene for MassSpec and Protein Over-expression Lysates for CBY3
- Origene Custom Protein Services for CBY3
- Novus Biologicals proteins for CBY3
- Search GeneTex for Proteins for CBY3
Assay Products
No data available for DME Specific Peptides for CBY3 Gene
Domains & Families for CBY3 Gene
Protein Domains for CBY3 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for CBY3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
A6NI87- Family:
-
- Belongs to the chibby family.
No data available for Gene Families for CBY3 Gene
Function for CBY3 Gene
Phenotypes for CBY3 Gene
- GenomeRNAi human phenotypes for CBY3:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CBY3
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CBY3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CBY3 gene
- Search ViGene Biosciences for CBY3
CRISPR Products
-
OriGene CRISPR knockouts for CBY3
-
Santa Cruz Biotechnology (SCBT) CRISPR for CBY3
- GenScript: Design CRISPR guide RNA sequences for CBY3
miRNA for CBY3 Gene
- miRTarBase miRNAs that target CBY3
-
- hsa-mir-1273e (MIRT550590)
- hsa-mir-5192 (MIRT550591)
- hsa-mir-4722-5p (MIRT550592)
- hsa-mir-1827 (MIRT550593)
- hsa-mir-4649-3p (MIRT550594)
- hsa-mir-6840-3p (MIRT550595)
- hsa-mir-665 (MIRT550596)
- hsa-mir-4459 (MIRT550597)
- hsa-mir-4768-3p (MIRT550598)
- hsa-mir-940 (MIRT550599)
- hsa-mir-6893-5p (MIRT550600)
- hsa-mir-4695-5p (MIRT550601)
- hsa-mir-6808-5p (MIRT550602)
- hsa-mir-6749-3p (MIRT610312)
- hsa-mir-623 (MIRT610313)
- hsa-mir-4669 (MIRT610314)
- hsa-mir-3657 (MIRT610315)
- hsa-mir-6852-3p (MIRT610316)
- hsa-mir-3909 (MIRT610317)
- hsa-mir-2116-3p (MIRT610318)
- hsa-mir-6780b-3p (MIRT610319)
- hsa-mir-4780 (MIRT610320)
- hsa-mir-6866-3p (MIRT610321)
- hsa-mir-188-5p (MIRT610322)
- hsa-mir-892a (MIRT610323)
- hsa-mir-8485 (MIRT610324)
- hsa-mir-548g-3p (MIRT610325)
- hsa-mir-466 (MIRT613862)
- hsa-mir-4672 (MIRT613863)
- hsa-mir-3941 (MIRT613864)
- hsa-mir-603 (MIRT613865)
- hsa-mir-362-3p (MIRT613866)
- hsa-mir-329-3p (MIRT613867)
- hsa-mir-6513-5p (MIRT670263)
- hsa-mir-887-5p (MIRT670264)
- hsa-mir-3913-5p (MIRT670265)
- hsa-mir-3122 (MIRT670266)
- hsa-mir-450a-1-3p (MIRT670267)
- hsa-mir-6779-5p (MIRT670268)
- hsa-mir-6780a-5p (MIRT670269)
- hsa-mir-3689c (MIRT670270)
- hsa-mir-3689b-3p (MIRT670271)
- hsa-mir-3689a-3p (MIRT670272)
- hsa-mir-30b-3p (MIRT670273)
- hsa-mir-1273h-5p (MIRT670274)
- hsa-mir-6788-5p (MIRT670275)
- hsa-mir-30c-2-3p (MIRT670276)
- hsa-mir-30c-1-3p (MIRT670277)
- hsa-mir-6740-5p (MIRT670278)
- hsa-mir-6799-5p (MIRT670279)
- hsa-mir-6883-5p (MIRT670280)
- hsa-mir-6785-5p (MIRT670281)
- hsa-mir-4728-5p (MIRT670282)
- hsa-mir-149-3p (MIRT670283)
- hsa-mir-7106-5p (MIRT670284)
- hsa-mir-662 (MIRT670285)
- hsa-mir-24-3p (MIRT671595)
- hsa-mir-4284 (MIRT671596)
- hsa-mir-4668-5p (MIRT722023)
- hsa-mir-194-5p (MIRT722024)
- hsa-mir-6735-3p (MIRT722025)
- hsa-mir-6768-3p (MIRT722026)
miRNA Products
- Search ViGene Biosciences for CBY3
Inhibitory RNA Products
- Origene RNAi and siRNA products in human, mouse, rat for CBY3
- Browse OriGene Inhibitory RNA Products For CBY3
-
ViGene Biosciences ready-to-package AAV shRNAs for CBY3 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for CBY3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CBY3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CBY3
-
ViGene Biosciences adenoviral particle packaged cDNA for CBY3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CBY3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CBY3 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CBY3 Gene
Localization for CBY3 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 3 |
| cytosol | 2 |
| extracellular | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CBY3 Gene
Transcripts for CBY3 Gene
mRNA/cDNA for CBY3 Gene
- (2) REFSEQ mRNAs :
- (0) Additional mRNA sequences :
- -
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CBY3 Gene
- Chibby homolog 3 (Drosophila):
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for CBY3
-
Santa Cruz Biotechnology (SCBT) CRISPR for CBY3
- GenScript: Design CRISPR guide RNA sequences for CBY3
miRNA Products
- Search ViGene Biosciences for CBY3
Inhibitory RNA Products
- Origene RNAi and siRNA products in human, mouse, rat for CBY3
- Browse OriGene Inhibitory RNA Products For CBY3
-
ViGene Biosciences ready-to-package AAV shRNAs for CBY3 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for CBY3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CBY3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for CBY3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for CBY3 Gene
This gene is overexpressed in Testis (x24.0).
NURSA nuclear receptor signaling pathways regulating expression of CBY3 Gene:
CBY3SOURCE GeneReport for Unigene cluster for CBY3 Gene:
Hs.535767Primer Products
No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CBY3 Gene
Orthologs for CBY3 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| dog (Canis familiaris) |
Mammalia | CBY3 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | CBY3 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Cby3 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Cby3 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | CBY3 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | CBY3 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | CBY3 35 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | cby1 35 |
|
OneToMany |
- Species where no ortholog for CBY3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- chimpanzee (Pan troglodytes)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for CBY3 Gene
(1) SIMAP similar genes for CBY3 Gene using alignment to 1 proteins:
Variants for CBY3 Gene
| SNP ID | Clin | Chr 05 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000132233 | -- | 179,680,792(+) | AGCAG(A/G)GTTCC | intron-variant | |
| rs1000647566 | -- | 179,679,366(+) | TGCGG(C/T)TGTGT | intron-variant | |
| rs1000754389 | -- | 179,683,823(+) | GCCAC(C/T)GCGCC | intron-variant, upstream-variant-2KB | |
| rs1000933856 | -- | 179,681,301(+) | ACAGG(A/C)ATTTG | intron-variant, upstream-variant-2KB, utr-variant-5-prime | |
| rs1001363741 | -- | 179,682,467(+) | GCACC(C/T)TGGGA | intron-variant, upstream-variant-2KB |
Gene Damage Index Score:
3.77;
57.98% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CBY3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CBY3
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CBY3 Gene
Disorders for CBY3 Gene
Relevant External Links for CBY3
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- CBY3
No disorders were found for CBY3 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CBY3 Gene
Publications for CBY3 Gene
- The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J. … Rubin E.M. (Nature 2004) 3 4 64
Products for CBY3 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for CBY3
- Search Origene for MassSpec and Protein Over-expression Lysates for CBY3
- Origene Custom Protein Services for CBY3
- Origene siRNA and RNAi products in human, mouse, rat for CBY3
- Browse OriGene Inhibitory RNA Products For CBY3
- Browse OriGene qPCR primer pairs and template standards
- OriGene CRISPR knockouts for CBY3
- OriGene ORF clones in human for CBY3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CBY3
- GenScript: Next-day shipping cDNA ORF clone for CBY3 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for CBY3
- GenScript Custom Assay Services for CBY3
- GenScript Custom overexpressing Cell Line Services for CBY3
- GenScript: Design CRISPR guide RNA sequences for CBY3
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for CBY3
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for CBY3
- Novus Biologicals proteins for CBY3
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Invitrogen Antibodies for CBY3
- ViGene Biosciences adenoviral particle packaged cDNA for CBY3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CBY3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CBY3 gene
- Search ViGene Biosciences for CBY3
- Horizon Cell Lines for CBY3
- Cyagen custom Knockout/knockin (KOKI) mouse models for CBY3
- VectorBuilder custom plasmid, inducible vectors for CBY3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CBY3
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CBY3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer