CBX8 Gene
protein-coding GIFtS: 49
GCID: GC17M077765
|
|
chromobox homolog 8(Previous name: chromobox homolog 8 (Drosophila Pc class) )
| |
Aliases
for CBX8 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromobox Homolog 81 2 | | Chromobox Protein Homolog 82 | | PC31 2 3 | | Pc Class 3 Homolog2 | | RC11 2 3 | | Polycomb 32 | | Rectachrome 12 3 | | Pc33 | | HPC31 | | HPc31 | | Chromobox Homolog 8 (Drosophila Pc Class)1 | | Polycomb 3 Homolog3 | | Chromobox Homolog 8 (Pc Class Homolog, Drosophila)2 | | |
Export aliases for CBX8 gene to outside databasesPrevious GC identifers: GC17M077418 GC17M081056 GC17M078332 GC17M078468 GC17M078452 GC17M075382 GC17M073209 |
Summaries
for CBX8 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: CBX8_HUMAN, Q9HC52Function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain thetranscriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex actsvia chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119',rendering chromatin heritably changed in its expressibility
Gene Wiki entry for CBX8
|
Genomic Views
for CBX8 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CBX8 gene promoter:
Pax-6 NF-kappaB c-Ets-1 Gfi-1 SRY POU2F1 NF-kappaB2 POU2F1a Pax-4a NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CBX8
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CBX8 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q25.3 Ensembl cytogenetic band: 17q25.3 HGNC cytogenetic band: 17q25.3CBX8 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M077765: view genomic region
(about GC identifiers)
Start:
|
77,765,931 bp from pter |
End:
|
77,775,482 bp from pter |
Size:
|
9,552 bases |
Orientation:
|
minus strand |
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Proteins
for CBX8 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CBX8_HUMAN, Q9HC52 (See
protein sequence)Recommended Name: Chromobox protein homolog 8 Size: 389 amino acids; 43396 Da
Subunit: Component of a PRC1-like complex. Interacts with RING1 RNF2, PCGF1, PCGF2, PCGF3, BMI1, PCGF5 AND PCGF6.Interacts with MLLT3 and histone H3. Interacts with PHC2 (By similarity)
Subcellular location: Nucleus
Miscellaneous: The human orthologuous proteins of Drosphila Polycomb group protein Pc, CBX2, CBX4, CBX6, CBX7 and CBX8,show distinct nulear localizations, contribute differently to transcriptional repression, and appear to be part ofdistinct PRC1-like protein complexes. The hPRC-H complex purification reported by PubMed:12167701 probably presents amixture of different complexes
1 PDB 3D structure from  and Proteopedia  for CBX8:3I91 (3D)
Secondary accessions: Q96H39 Q9NR07Explore the universe of human proteins at neXtProt for CBX8: NX_Q9HC52
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9HC52
CBX8 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_065700.1
ENSEMBL proteins: ENSP00000269385 ENSP00000405058 ENSP00000408753
Human Recombinant Protein Products:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
CBX8 for ontologies About GeneDecksing
CBX8 Antibody Products:
Assay Products for CBX8: |
Protein
Domains /
Families
for CBX8 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CBX8 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9HC52ProtoNet protein and cluster: Q9HC52 1 Blocks protein family: IPB000953 Chromo domain
UniProtKB/Swiss-Prot: CBX8_HUMAN, Q9HC52Similarity: Contains 1 chromo domain |
Function
for CBX8 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CBX8_HUMAN, Q9HC52Function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain thetranscriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex actsvia chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119',rendering chromatin heritably changed in its expressibility
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CBX8 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CBX8
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CBX8 (NM_020649) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CBX8 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CBX8 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBX8 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003727 | single-stranded RNA binding |
IEA | -- | | GO:0004842 | ubiquitin-protein ligase activity |
IEA | -- | | GO:0005515 | protein binding |
IPI | -- | | GO:0035064 | methylated histone residue binding |
IDA | -- |
CBX8 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Cbx8tm1.1Hko for CBX8
3 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Cbx8):
CBX8 for phenotypes About GeneDecksing
|
Pathways & Interactions
for CBX8 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CBX8
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/138 Interacting proteins for CBX8 (Q9HC521, 2, 3 ENSP000002693854) via UniProtKB, MINT, STRING, and/or I2D (see all 138)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| BMI1 | P352261, 2, 3, ENSP000003658514 | EBI-712912,EBI-2341576 MINT-8001998 MINT-8001923 MINT-4543665 MINT-8001946 MINT-4543725 MINT-8001976 MINT-8010325 MINT-4543674 I2D:
score=3 STRING: ENSP00000365851 | | USP11 | P517842, 3, ENSP000002183484 | MINT-8001998 MINT-8001923 MINT-7999851 MINT-8012669 MINT-8003609 MINT-8010390 MINT-8001946 MINT-8001976 MINT-8010325 MINT-7999719 I2D:
score=2 STRING: ENSP00000218348 | | USP7 | Q930092, 3, ENSP000003435354 | MINT-8001998 MINT-8001923 MINT-7999851 MINT-8010390 MINT-8001946 MINT-8010174 MINT-7999732 MINT-8001976 MINT-8002022 MINT-8012683 I2D:
score=2 STRING: ENSP00000343535 | | RNF2 | Q994961, 2, 3, ENSP000003564804 | EBI-712912,EBI-722416 MINT-8010390 MINT-8010325 MINT-4543689 I2D:
score=3 STRING: ENSP00000356480 | | PCGF2 | P352271, 2, 3, ENSP000003540334 | EBI-712912,EBI-2129767 MINT-8010390 MINT-8001946 MINT-8001976 I2D:
score=1 STRING: ENSP00000354033 |
About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000122 | negative regulation of transcription from RNA polymerase II promoter |
IMP | 19636380 | | GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0016574 | histone ubiquitination |
IEA | -- |
CBX8 for ontologies About GeneDecksing
|
Drugs & Compounds
for CBX8 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CBX8
Search CenterWatch for drugs/clinical trials and news about CBX8
|
Transcripts
for CBX8 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CBX8 gene: NM_020649.2 Unigene Cluster for CBX8: Chromobox homolog 8 Hs.387258 [show with all ESTs]Unigene Representative Sequence: NM_0206494 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000269385(uc002jxd.2) ENST00000413392 ENST00000427800 ENST00000485449
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CBX8 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CBX8
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CBX8 (NM_020649) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CBX8 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CBX8 |
Additional cDNA sequence: AF174482.1 AF266479.2 AK074560.1 BC008937.2 BC009376.2 BC019289.1 2 DOTS entries: DT.65287151 DT.100840784 24/48 AceView cDNA sequences (see all 48): AK074560 BG248106 CD722217 AF174482 BQ425649 NM_020649 AW167196 BC019289 CR591848 AF266479 CR600853 BC009376 BC008937 BM799614 BI771784 BX641812 AL579037 BM465282 BE616878 AW161322 BE391068 BE222046 AL556925 BE892826
GeneLoc Exon Structure
|
Expression
for CBX8 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CBX8 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGGGCCCAGG
About this image
See CBX8 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CBX8
SOURCE GeneReport for Unigene cluster: Hs.387258
SABiosciences Expression via Pathway-Focused PCR Arrays including CBX8:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CBX8
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CBX8 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CBX8 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CBX8 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBX8 |
Orthologs
for CBX8 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CBX8 gene from 4/15 species (see all 15) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CBX81 |
chromobox homolog 8 |
72.86(n)
73.37(a) |
|
422084 XM_001231756.2 XP_001231757.2 |
lizard
(Anolis carolinensis) |
Reptilia |
CBX86 |
-- |
66(a) |
1 ↔ 1 |
2(100944705-100947355) |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.200342 |
Danio rerio polycomb 3 mRNA, complete cds |
74.06(n) |
|
AY179330.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Pc6 |
Polycomb |
19(a) |
1 → many |
3L(21299238-21311120) |
ENSEMBL Gene Tree for CBX8 (if available)
TreeFam Gene Tree for CBX8 (if available) |
Paralogs
for CBX8 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CBX8 gene
- CBX22 CBX42 CBX72
3 SIMAP similar genes for CBX8 using alignment to 3 protein entries: CBX8_HUMAN (see all proteins):CBX4 CBX7 CBX5
CBX8 for paralogs About GeneDecksing
|
Genomic Variants
for CBX8 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CBX8 (77765931 - 77775482 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for CBX8
2 CNVs: 0213 2234 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CBX8 |
|
Disorders
/ Diseases
for CBX8 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CBX8 for disorders About GeneDecksing
4  diseases for CBX8: About MalaCardsmouth disease childhood leukemia acute leukemia leukemia
Export disorders for CBX8 gene to outside databases
|
Publications
for CBX8 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CBX8 gene, integrated from 9 sources (see all 26):
(articles sorted by number of sources associating them with CBX8) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties. (PubMed id 10825164)1, 2, 3, 9 Bardos J.I.... Freemont P.S. (2000)
- Several distinct polycomb complexes regulate and co-l ocalize on the INK4a tumor suppressor locus. (PubMed id 19636380)1, 2, 9 Maertens G.N....Peters G. (2009)
- Recognition and specificity determinants of the human cbx chromodomains. (PubMed id 21047797)1, 2 Kaustov L.... Arrowsmith C.H. (2011)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans. (PubMed id 12167701)1, 2 Levine S.S....Kingston R.E. (2002)
- The ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3. (PubMed id 11313972)1, 2 Garcia-Cuellar M.P.... Slany R.K. (2001)
- Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus. (PubMed id 17332741)1, 9 Dietrich N....Hansen K.H. (2007)
- A phosphorylated form of Mel-18 targets the Ring1B histone H2A ubiquitin ligase to chromatin. (PubMed id 17936708)1, 9 Elderkin S....Hiom K. (2007)
- Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase. (PubMed id 15009096)1, 9 Obuse C....Yoda K. (2004)
|
External Searches for CBX8 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CBX8 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CBX8 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CBX8 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CBX8 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CBX8 gene:
Search GeneIP for patents involving CBX8
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CBX8 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for CBX8 | | OriGene shRNA RFP for CBX8 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CBX8 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CBX8 | | | OriGene Protein Over-expression Lysate for CBX8 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CBX8 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CBX8 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CBX8 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CBX8 | | OriGene Custom Protein Services for CBX8 | | | OriGene Custom Immunoassay Development | | |
| |
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 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CBX8 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CBX8 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CBX8 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CBX8 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CBX8 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CBX8 |
| |
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| | | | Search Tocris compounds for CBX8 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | CBX8 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBX8 |
|  |  |  | | | | ThermoFisher Antibodies for CBX8 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CBX8 |
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