GeneCards Summary for CBX6 Gene
CBX6 (Chromobox Homolog 6) is a Protein Coding gene. Among its related pathways are Cellular Senescence and Cellular Senescence. GO annotations related to this gene include single-stranded RNA binding. An important paralog of this gene is CBX4.
UniProtKB/Swiss-Prot for CBX6 Gene
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A Lys-119, rendering chromatin heritably changed in its expressibility.