CBX3 Gene
protein-coding GIFtS: 60
GCID: GC07P026207
|
|
chromobox homolog 3(Previous name: chromobox homolog 3 (Drosophila HP1 gamma) )
| |
Aliases
for CBX3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromobox Homolog 31 2 | | Chromobox Homolog 3 (HP1 Gamma Homolog, Drosophila)2 | | HP1Hs-Gamma1 | | Chromobox Protein Homolog 32 | | Heterochromatin Protein 1 Homolog Gamma2 3 | | Heterochromatin Protein HP1 Gamma2 | | Modifier 2 Protein2 3 | | Heterochromatin-Like Protein 12 | | HECH2 3 | | HP1 Gamma Homolog2 | | Chromobox Homolog 3 (Drosophila HP1 Gamma)1 | | HP1 Gamma3 | | HP1-GAMMA2 | | |
Export aliases for CBX3 gene to outside databasesPrevious GC identifers: GC07P025883 GC07P025983 GC07P026014 |
Summaries
for CBX3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CBX3:
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The proteinencoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, anintegral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein mayexplain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tailsmethylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strandbreaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for thisgene.(provided by RefSeq, Mar 2011)
UniProtKB/Swiss-Prot: CBX3_HUMAN, Q13185Function: Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and bindshistone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of theheterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in theformation of functional kinetochore through interaction with MIS12 complex proteins
Gene Wiki entry for CBX3
|
Genomic Views
for CBX3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007819.17 NT_079592.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CBX3 gene promoter:
STAT1 p53
Other transcription factors
Search SABiosciences Chromatin IP Primers for CBX3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CBX3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7p15.2 Ensembl cytogenetic band: 7p15.2 HGNC cytogenetic band: 7p15.2CBX3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P026207: view genomic region
(about GC identifiers)
Start:
|
26,240,782 bp from pter |
End:
|
26,252,976 bp from pter |
Size:
|
12,195 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 26,292,249-26,304,123 |
|
Proteins
for CBX3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CBX3_HUMAN, Q13185 (See
protein sequence)Recommended Name: Chromobox protein homolog 3 Size: 183 amino acids; 20811 Da
Subunit: Binds directly to CHAF1A. Interacts with histone H3 methylated at 'Lys-9'. Part of the E2F6.com-1 complex inG0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, L3MBTL2 and YAF2. Interacts withLBR, INCENP, TRIM28/TIF1B, SUV420H1, SUV420H2 and SP100. Interacts with TIF1A (By similarity). Interacts with MIS12and DSN1. Can interact directly with CBX5 via the chromoshadow domain. Interacts with POGZ. Interacts with CHAMP1.Interacts with ASXL1
Subcellular location: Nucleus (Potential). Note=Associates with euchromatin and is largely excluded from constitutiveheterochromatin. May be associated with microtubules and mitotic poles during mitosis (Potential)
4 PDB 3D structures from  and Proteopedia  for CBX3:2L11 (3D)
3DM1 (3D)
3KUP (3D)
3TZD (3D)
Secondary accessions: Q96CD7 Q99409 Q9BVS3 Q9P0Z6Explore the universe of human proteins at neXtProt for CBX3: NX_Q13185
Post-translational modifications:
Phosphorylated by PIM1. Phosphorylated during interphase and possibly hyper-phosphorylated during mitosis1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q13185
CBX3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_009207.2 NP_057671.2
ENSEMBL proteins: ENSP00000336687 ENSP00000379670 ENSP00000408672 ENSP00000387348
Human Recombinant Protein Products:
Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9): About this table
CBX3 for ontologies About GeneDecksing
CBX3 Antibody Products:
Assay Products for CBX3: |
Protein
Domains /
Families
for CBX3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CBX3 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q13185ProtoNet protein and cluster: Q13185 2 Blocks protein families: IPB000953 Chromo domain IPB008251 Chromo shadow
UniProtKB/Swiss-Prot: CBX3_HUMAN, Q13185Similarity: Contains 2 chromo domains |
Function
for CBX3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CBX3_HUMAN, Q13185Function: Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and bindshistone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of theheterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in theformation of functional kinetochore through interaction with MIS12 complex proteins
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CBX3 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CBX3 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for CBX3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CBX3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBX3 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
CBX3 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for CBX3:
Animal Models:
Mouse knock-out Cbx3tm1Ics for CBX3
5 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Cbx3):
CBX3 for phenotypes About GeneDecksing
|
Pathways & Interactions
for CBX3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Chromatin Regulation / Acetylation | | | 2 | Diurnally regulated genes with circadian orthologs | | | 3 | Signal transduction Activin A signaling regulation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for CBX3
1 
Cell Signaling Technology (CST) Pathway for CBX3
1  BioSystems Pathway for CBX3
CBX3 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CBX3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/124 Interacting proteins for CBX3 (Q131851, 2, 3 ENSP000003366874) via UniProtKB, MINT, STRING, and/or I2D (see all 124)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
CBX3 for ontologies About GeneDecksing
|
Drugs & Compounds
for CBX3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CBX3
Search CenterWatch for drugs/clinical trials and news about CBX3
|
Transcripts
for CBX3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CBX3 gene (2 alternative transcripts): NM_007276.4 NM_016587.3 Unigene Cluster for CBX3: Chromobox homolog 3 Hs.381189 [show with all ESTs]Unigene Representative Sequence: NM_0072768 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000337620(uc003sxt.3) ENST00000396386(uc003sxu.3 uc003sxv.3)
ENST00000456948 ENST00000409747 ENST00000497498 ENST00000481300 ENST00000462165
ENST00000481057
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CBX3 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CBX3 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): CBX3 (NM_016587) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CBX3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CBX3 |
Additional cDNA sequence: AB030905.1 AF086270.1 AF136630.1 BC000954.1 BC014380.1 BX647444.1 BX648807.1 U26312.1 24/40 DOTS entries (see all 40): DT.97765315 DT.95135225 DT.452181 DT.100888406 DT.100717749 DT.97857245 DT.100888412 DT.100888382 DT.92339082 DT.100888397 DT.100888409 DT.75101118 DT.92463362 DT.95080266 DT.91939916 DT.95135244 DT.100756428 DT.121311080 DT.91719027 DT.121044034 DT.100888404 DT.121311083 DT.100888400 DT.120692156 24/864 AceView cDNA sequences (see all 864): AW238854 AW009823 BE328643 CD514780 BM717815 AI341188 AL548092 AI800064 BM472699 AW009092 BM832956 AA011120 AW080274 AA765379 W39742 AW613400 AA568376 AW474221 BM982716 CR605399 AA926777 CN481765 AA284411 CA392800
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for CBX3 (see all 8) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | · | 8d |
|---|
|
| SP1: | | | - | | - | | - | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | - | | | | | | | | - | | - | | - | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | - | | - | | | | | | - | | - | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CBX3
|
Expression
for CBX3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CBX3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGGCTCAAT
About this image
See CBX3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CBX3
SOURCE GeneReport for Unigene cluster: Hs.381189
SABiosciences Expression via Pathway-Focused PCR Arrays including CBX3: | Polycomb & Trithorax Complexes in human mouse rat | | Epigenetic Chromatin Remodeling Factors in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CBX3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CBX3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CBX3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CBX3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBX3 |
Orthologs
for CBX3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CBX3 gene from 8/22 species (see all 22) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
O93481_CHICK6 |
chromobox homolog 3 (HP1 gamma homolog, Drosophila... |
96(a) |
1 ↔ 1 |
2(32127948-32141073) |
lizard
(Anolis carolinensis) |
Reptilia |
CBX36 |
-- |
93(a) |
1 ↔ 1 |
6(31866784-31876239) |
African clawed frog
(Xenopus laevis) |
Amphibia |
BC046570.12 |
-- |
83.16(n) |
|
BC046570.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
cbx3a6cbx3b6 |
chromobox homolog 3b |
77(a)44(a) |
1 ↔ many1 ↔ many |
19(20267100-20270413) 16(23122950-23132302) |
fruit fly
(Drosophila melanogaster) |
Insecta |
HP1b3 |
chromatin binding |
56(a) |
|
8C7 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
hpl-16 |
HP1 Like (heterochromatin protein) family member (... |
28(a) |
possible ortholog |
X(13245321-13246975) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
TFL26 |
chromo domain-containing protein LHP1 |
10(a) |
1 → many |
5(5827171-5829682) |
rice
(Oryza sativa) |
Liliopsida |
-- |
chromo domain-containing protein LHP1, putative, e... |
9(a) |
1 → many |
10(8921155-8925965) |
ENSEMBL Gene Tree for CBX3 (if available)
TreeFam Gene Tree for CBX3 (if available) |
Paralogs
for CBX3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CBX3 gene
- MPHOSPH82 CBX12 CBX52
4 SIMAP similar genes for CBX3 using alignment to 4 protein entries: CBX3_HUMAN (see all proteins):CBX1 CBX4 LOC645158 CBX5
CBX3 for paralogs About GeneDecksing
5/9 Pseudogenes.org Pseudogenes for CBX3 (see all 9)
PGOHUM00000242404 PGOHUM00000242624 PGOHUM00000242686 PGOHUM00000239295 PGOHUM00000239549
|
Genomic Variants
for CBX3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CBX3 (26240782 - 26252976 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for CBX3
2 CNVs: 44303 69832
1 Indel: 40962 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CBX3 |
|
Disorders
/ Diseases
for CBX3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CBX3 for disorders About GeneDecksing
OMIM gene information: 604477
OMIM disorders: --
7  diseases for CBX3: About MalaCardsherpes simplex cockayne syndrome ovarian cancer ataxia
thyroiditis leukemia neuronitis
Export disorders for CBX3 gene to outside databases
|
Publications
for CBX3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CBX3 gene, integrated from 9 sources (see all 134):
(articles sorted by number of sources associating them with CBX3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1. (PubMed id 8663349)1, 2, 3 Ye Q. and Worman H.J. (1996)
- Identification of heterochromatin protein 1 (HP1) as a phosphorylation target by Pim-1 kinase and the effect of phosphorylation on the transcriptional repression function of HP1. (PubMed id 10664448)1, 2, 9 Koike N.... Iguchi-Ariga S.M.M. (2000)
- Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells. (PubMed id 10460410)1, 2, 9 Minc E.... Buendia B. (1999)
- A complex with chromatin modifiers that occupies E2F- and Myc- responsive genes in G0 cells. (PubMed id 12004135)1, 2, 9 Ogawa H.... Nakatani Y. (2002)
- KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Kruppel-associated box-zinc finger proteins in heterochromatin- mediated gene silencing. (PubMed id 10330177)1, 2, 9 Ryan R.F.... Rauscher F.J. III (1999)
- Human POGZ modulates dissociation of HP1alpha from mi totic chromosome arms through Aurora B activation. (PubMed id 20562864)1, 2 Nozawa R.S....Obuse C. (2010)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1. (PubMed id 15502821)1, 2 Obuse C....Yanagida M. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
|
External Searches for CBX3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CBX3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CBX3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CBX3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for CBX3 gene:
Search GeneIP for patents involving CBX3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CBX3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for CBX3 | | OriGene shRNA RFP for CBX3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CBX3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CBX3 | | | OriGene Protein Over-expression Lysate for CBX3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CBX3 | | OriGene 3'-UTR Clone for CBX3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CBX3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CBX3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CBX3 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CBX3 | | OriGene Custom Protein Services for CBX3 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CBX3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CBX3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CBX3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CBX3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CBX3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CBX3 |
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| | Antibodies & Assays for CBX3 |
| | | | Search Tocris compounds for CBX3 |
| |  |  |  |  | | | | | | Recombinant Protein for CBX3 |
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 | | | CBX3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBX3 |
|  |  |  | | | | ThermoFisher Antibodies for CBX3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CBX3 |
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