Aliases for CBX1 Gene
Aliases for CBX1 Gene
External Ids for CBX1 Gene
- HGNC: 1551
- Entrez Gene: 10951
- Ensembl: ENSG00000108468
- OMIM: 604511
- UniProtKB: P83916
Previous GeneCards Identifiers for CBX1 Gene
- GC17M045852
- GC17M048627
- GC17M046489
- GC17M046622
- GC17M043502
- GC17M046147
- GC17M041515
Summaries for CBX1 Gene
-
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for CBX1 Gene
CBX1 (Chromobox 1) is a Protein Coding gene. Diseases associated with CBX1 include Mandibuloacral Dysplasia. Among its related pathways are Chromatin Regulation / Acetylation. GO annotations related to this gene include protein homodimerization activity and chromatin binding. An important paralog of this gene is CBX3.
UniProtKB/Swiss-Prot for CBX1 Gene
-
Component of heterochromatin. Recognizes and binds histone H3 tails methylated at Lys-9, leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CBX1 Gene
Genomics for CBX1 Gene
Regulatory Elements for CBX1 Gene
Enhancers for CBX1 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CBX1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the CBX1 gene promoter:
Regulatory Element Products
Genomic Location for CBX1 Gene
- Chromosome:
- 17
- Start:
- 48,070,052 bp from pter
- End:
- 48,101,521 bp from pter
- Size:
- 31,470 bases
- Orientation:
- Minus strand
Genomic View for CBX1 Gene
Genes around CBX1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q21.32 by Ensembl
- 17q21.32 by Entrez Gene
- 17q21.32 by HGNC
CBX1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CBX1 Gene
Proteins for CBX1 Gene
-
Protein details for CBX1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P83916-CBX1_HUMAN
- Recommended name:
- Chromobox protein homolog 1
- Protein Accession:
- P83916
- P23197
Protein attributes for CBX1 Gene
- Size:
- 185 amino acids
- Molecular mass:
- 21418 Da
- Quaternary structure:
-
- Homodimer. Interacts directly with CHAF1A, EMSY, LBR, TIF1/TIF1A and TRIM28/TIF1B PXVXL motif via the chromoshadow domain. Interacts directly with histone H3 methylated at Lys-9 via the chromo domain. Interacts with SUV39H1 and SETDB1, KMT5B and KMT5C. Interacts with PRDM6. Interacts with POGZ. Interacts with CHAMP1. Interacts with ASXL1. Interacts with INCENP. Interacts with SGO1; the CBX1 homodimer binds to one molecule of SGO1.
Protein Expression for CBX1 Gene
Post-translational modifications for CBX1 Gene
- Not phosphorylated.
- Ubiquitinated.
- Ubiquitination at posLast=2525, Lys43, Lys139, and posLast=150150
- Modification sites at PhosphoSitePlus
Other Protein References for CBX1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for CBX1
- Cell Signaling Technology (CST) Antibodies for CBX1 (CBX1)
-
Custom Antibody ServicesOriGene Antibodies for CBX1
- Novus Biologicals Antibodies for CBX1
- Invitrogen Antibodies for CBX1
- antibodies-online Antibodies for CBX1: See all 92
- GeneTex CBX1 antibody for CBX1
-
Santa Cruz Biotechnology (SCBT) Antibodies for CBX1
Protein Products
-
OriGene Purified Proteins for CBX1
- Search Origene for MassSpec and Protein Over-expression Lysates for CBX1
- Origene Custom Protein Services for CBX1
- ProSpec Recombinant Proteins for CBX1
- antibodies-online Proteins for CBX1: See all 10
- Search antibodies-online for peptides
- Search GeneTex for Proteins for CBX1
Assay Products
- antibodies-online Kits for CBX1: See all 4
No data available for DME Specific Peptides for CBX1 Gene
Domains & Families for CBX1 Gene
Gene Families for CBX1 Gene
- HGNC:
Protein Domains for CBX1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CBX1 Gene
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for CBX1 Gene
Function for CBX1 Gene
Molecular function for CBX1 Gene
- UniProtKB/Swiss-Prot Function:
- Component of heterochromatin. Recognizes and binds histone H3 tails methylated at Lys-9, leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003682 | chromatin binding | TAS | 9169582 |
| GO:0005515 | protein binding | IPI | 9636146 |
| GO:0019899 | enzyme binding | IPI | 19486527 |
| GO:0042802 | identical protein binding | IEA | -- |
| GO:0042803 | protein homodimerization activity | IEA | -- |
Phenotypes for CBX1 Gene
- MGI mutant phenotypes for CBX1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for CBX1:
-
- Increased vaccinia virus (VACV) infection
- Decreased viability
- Decreased viability in esophageal squamous lineage
- Dynamic nuclei (hole, folded or small irregular)
- Decreased NF-kappaB reporter expression
- Decreased number of cells in monopolar arrest with EMD534085 (a Kinesin-5 inhibitor)
- Decreased Hepatitis C virus replication
- Increased Nanog expression
- Decreased DCP1a protein expression and assembly in processing bodies after arsenite stimulation
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CBX1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CBX1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CBX1 gene
- Search ViGene Biosciences for CBX1
CRISPR Products
-
OriGene CRISPR knockouts for CBX1
-
Santa Cruz Biotechnology (SCBT) CRISPR for CBX1
- GenScript: Design CRISPR guide RNA sequences for CBX1
miRNA for CBX1 Gene
- miRTarBase miRNAs that target CBX1
-
- hsa-mir-210-3p (MIRT003170)
- hsa-mir-590-3p (MIRT016166)
- hsa-mir-193b-3p (MIRT016475)
- hsa-mir-186-5p (MIRT021150)
- hsa-mir-877-3p (MIRT037076)
- hsa-mir-342-3p (MIRT043713)
- hsa-mir-218-5p (MIRT440999)
- hsa-mir-5010-3p (MIRT558917)
- hsa-mir-2113 (MIRT558918)
- hsa-mir-147a (MIRT558919)
- hsa-mir-6818-5p (MIRT558920)
- hsa-mir-297 (MIRT558921)
- hsa-mir-19b-2-5p (MIRT558922)
- hsa-mir-19b-1-5p (MIRT558923)
- hsa-mir-19a-5p (MIRT558924)
- hsa-mir-2052 (MIRT558925)
- hsa-mir-6867-5p (MIRT558926)
- hsa-mir-223-5p (MIRT558927)
- hsa-mir-567 (MIRT558928)
- hsa-mir-4455 (MIRT558929)
- hsa-mir-876-5p (MIRT558930)
- hsa-mir-3167 (MIRT558931)
- hsa-mir-302a-5p (MIRT558932)
- hsa-mir-511-3p (MIRT558933)
- hsa-mir-4796-3p (MIRT558934)
- hsa-mir-93-5p (MIRT558935)
- hsa-mir-526b-3p (MIRT558936)
- hsa-mir-519d-3p (MIRT558937)
- hsa-mir-20b-5p (MIRT558938)
- hsa-mir-20a-5p (MIRT558939)
- hsa-mir-17-5p (MIRT558940)
- hsa-mir-106b-5p (MIRT558941)
- hsa-mir-106a-5p (MIRT558942)
- hsa-mir-548ah-5p (MIRT558943)
- hsa-mir-3609 (MIRT558944)
miRNA Products
- Search ViGene Biosciences for CBX1
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CBX1
- Browse OriGene Inhibitory RNA Products For CBX1
-
ViGene Biosciences ready-to-package AAV shRNAs for CBX1 gene
Clone Products
- Sino Biological Human cDNA Clone for CBX1
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- Addgene plasmids for CBX1
- VectorBuilder custom plasmid, inducible vectors for CBX1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CBX1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CBX1
-
ViGene Biosciences adenoviral particle packaged cDNA for CBX1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CBX1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CBX1 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CBX1 Gene
Localization for CBX1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CBX1 Gene
- Nucleus. Note=Unassociated with chromosomes during mitosis.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| nucleus | 5 |
| cytosol | 2 |
| golgi apparatus | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000775 | chromosome, centromeric region | IDA | 8287692 |
| GO:0000784 | colocalizes_with nuclear chromosome, telomeric region | IDA | 24270157 |
| GO:0000785 | chromatin | IDA | 11101528 |
| GO:0001939 | female pronucleus | IEA | -- |
| GO:0001940 | male pronucleus | IEA | -- |
Pathways & Interactions for CBX1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Chromatin Regulation / Acetylation | ||
Pathways by source for CBX1 Gene
1 Cell Signaling Technology pathway for CBX1 Gene
Interacting Proteins for CBX1 Gene
Selected Interacting proteins:
P83916-CBX1_HUMAN
ENSP00000225603
for CBX1 Gene via
UniProtKB
STRING
MINT
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0045892 | negative regulation of transcription, DNA-templated | IEA | -- |
Transcripts for CBX1 Gene
mRNA/cDNA for CBX1 Gene
- (2) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (507) Selected AceView cDNA sequences:
- (6) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for CBX1
-
Santa Cruz Biotechnology (SCBT) CRISPR for CBX1
- GenScript: Design CRISPR guide RNA sequences for CBX1
miRNA Products
- Search ViGene Biosciences for CBX1
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CBX1
- Browse OriGene Inhibitory RNA Products For CBX1
-
ViGene Biosciences ready-to-package AAV shRNAs for CBX1 gene
Clone Products
- Sino Biological Human cDNA Clone for CBX1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for CBX1
- VectorBuilder custom plasmid, inducible vectors for CBX1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CBX1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||
| SP2: | - | ||||||||||||||||
| SP3: | - | ||||||||||||||||
| SP4: |
Expression for CBX1 Gene
This gene is overexpressed in Peripheral blood mononuclear cells (13.3), Liver (12.0), and Fetal ovary (6.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CBX1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of CBX1 Gene:
CBX1SOURCE GeneReport for Unigene cluster for CBX1 Gene:
Hs.77254mRNA Expression by UniProt/SwissProt for CBX1 Gene:
P83916-CBX1_HUMAN
Tissue specificity:
Expressed in all adult and embryonic tissues.
Evidence on tissue expression from TISSUES for CBX1 Gene
- Nervous system(4.8)
- Liver(4.3)
- Lung(2.8)
- Eye(2.3)
- Muscle(2.2)
Primer Products
-
OriGene qPCR primer pairs and template standards for CBX1
-
OriGene qPCR primer pairs for CBX1
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for CBX1 Gene
Orthologs for CBX1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CBX1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | CBX1 35 |
|
OneToOne | |
| LOC101904753 34 |
|
||||
| oppossum (Monodelphis domestica) |
Mammalia | CBX1 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | CBX1 35 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | CBX1 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Cbx1 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Cbx1 34 |
|
||
| chicken (Gallus gallus) |
Aves | CBX1 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | CBX1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | cbx1 34 |
|
||
| Str.16928 34 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | cbx1b 34 35 |
|
||
| cbx1a 35 |
|
OneToMany | |||
| -- 34 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.10237 34 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP004723 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | HP1b 36 34 35 |
|
||
| HP6 35 |
|
ManyToMany | |||
| Su(var)205 35 |
|
ManyToMany | |||
| HP1e 35 |
|
ManyToMany | |||
| HP1c 35 |
|
ManyToMany | |||
| worm (Caenorhabditis elegans) |
Secernentea | hpl-1 35 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.3133 35 |
|
OneToMany |
- Species where no ortholog for CBX1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for CBX1 Gene
(10) SIMAP similar genes for CBX1 Gene using alignment to 7 proteins:
Pseudogenes.org Pseudogenes for CBX1 Gene
Variants for CBX1 Gene
| SNP ID | Clin | Chr 17 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000041252 | -- | 48,102,266(+) | GACCA(A/G)CCTGG | upstream-variant-2KB | |
| rs1000050851 | -- | 48,084,594(+) | ATGGC(A/G)CCCTG | intron-variant | |
| rs1000113924 | -- | 48,085,009(+) | TACAG(C/T)ATGTA | intron-variant | |
| rs1000249796 | -- | 48,101,230(+) | GCGCC(C/T)CCTCC | intron-variant, upstream-variant-2KB | |
| rs1000351057 | -- | 48,071,729(+) | ACTGG(A/C)AATTG | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv1003767 | CNV | insertion | 20482838 |
| esv2582446 | CNV | deletion | 19546169 |
| esv2663382 | CNV | deletion | 23128226 |
| esv2716011 | CNV | deletion | 23290073 |
| esv3310437 | CNV | novel sequence insertion | 20981092 |
| esv3410940 | CNV | duplication | 20981092 |
| esv3582798 | CNV | loss | 25503493 |
| esv3640709 | CNV | loss | 21293372 |
| esv3640710 | CNV | gain | 21293372 |
| esv3640711 | CNV | loss | 21293372 |
| esv3640712 | CNV | loss | 21293372 |
| nsv469808 | CNV | loss | 16826518 |
| nsv513477 | CNV | insertion | 21212237 |
| nsv962336 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
44.4% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CBX1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CBX1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CBX1 Gene
Disorders for CBX1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| mandibuloacral dysplasia |
|
|
Search CBX1 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for CBX1
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- CBX1
No data available for UniProtKB/Swiss-Prot and Genatlas for CBX1 Gene
Publications for CBX1 Gene
- Heterochromatin protein HP1Hsbeta (p25beta) and its localization with centromeres in mitosis. (PMID: 9169582) Furuta K. … Tan E.M. (Chromosoma 1997) 2 3 4 22 64
- In vivo HP1 targeting causes large-scale chromatin condensation and enhanced histone lysine methylation. (PMID: 15899859) Verschure P.J. … van Driel R. (Mol. Cell. Biol. 2005) 3 4 22 64
- Binding of EMSY to HP1beta: implications for recruitment of HP1beta and BS69. (PMID: 15947784) Ekblad C.M.S. … Itzhaki L.S. (EMBO Rep. 2005) 3 4 22 64
- Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells. (PMID: 10460410) Minc E. … Buendia B. (Chromosoma 1999) 3 4 22 64
- Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells. (PMID: 21346195) Kang J. … Yu H. (Mol. Biol. Cell 2011) 3 4 64
Products for CBX1 Gene
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- OriGene qPCR primer pairs and template standards for CBX1
- OriGene qPCR primer pairs for CBX1
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- Cell Signaling Technology (CST) Antibodies for CBX1 (CBX1)
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- Novus Biologicals Antibodies for CBX1
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- Novus Biologicals
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- ProSpec Recombinant Proteins for CBX1
- Addgene plasmids for CBX1
- antibodies-online Antibodies for CBX1: See all 92
- antibodies-online Kits for CBX1: See all 4
- antibodies-online Proteins for CBX1: See all 10
- Search antibodies-online for peptides
- GeneTex CBX1 antibody for CBX1
- Search GeneTex for Proteins for CBX1
- ViGene Biosciences adenoviral particle packaged cDNA for CBX1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CBX1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CBX1 gene
- Search ViGene Biosciences for CBX1
- Santa Cruz Biotechnology (SCBT) Antibodies for CBX1
- Search Santa Cruz Biotechnology (SCBT) for CBX1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CBX1
- Horizon Cell Lines for CBX1
- Cyagen custom Knockout/knockin (KOKI) mouse models for CBX1
- VectorBuilder custom plasmid, inducible vectors for CBX1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CBX1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CBX1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
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