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Aliases for CBWD5 Gene

Aliases for CBWD5 Gene

  • COBW Domain Containing 5 2 3
  • Cobalamin Synthase W Domain-Containing Protein 5 3 4
  • Dopamine Responsive Protein 2 3
  • Cobalamin Synthetase W Domain-Containing Protein 5 3
  • COBW Domain-Containing Protein 5 3
  • COBW-Like Placental Protein 3
  • DC36 3

External Ids for CBWD5 Gene

Summaries for CBWD5 Gene

GeneCards Summary for CBWD5 Gene

CBWD5 (COBW Domain Containing 5) is a Protein Coding gene. An important paralog of this gene is CBWD3.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CBWD5 Gene

Genomics for CBWD5 Gene

Genomic Location for CBWD5 Gene

Start:
65,668,805 bp from pter
End:
65,734,041 bp from pter
Size:
65,237 bases
Orientation:
Plus strand

Genomic View for CBWD5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CBWD5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CBWD5 Gene

Regulatory Elements for CBWD5 Gene

Proteins for CBWD5 Gene

  • Protein details for CBWD5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5RIA9-CBWD5_HUMAN
    Recommended name:
    COBW domain-containing protein 5
    Protein Accession:
    Q5RIA9
    Secondary Accessions:
    • Q8N7U8

    Protein attributes for CBWD5 Gene

    Size:
    395 amino acids
    Molecular mass:
    44068 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CBWD5 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CBWD5 Gene

Proteomics data for CBWD5 Gene at MOPED

Post-translational modifications for CBWD5 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys55, Lys69, Lys113, Lys176, Lys306, and Lys370

No data available for DME Specific Peptides for CBWD5 Gene

Domains for CBWD5 Gene

UniProtKB/Swiss-Prot:

CBWD5_HUMAN
Domain:
  • Contains 1 cobW C-terminal domain.:
    • Q5RIA9
Family:
  • Belongs to the CobW family.:
    • Q5RIA9
genes like me logo Genes that share domains with CBWD5: view

No data available for Gene Families for CBWD5 Gene

Function for CBWD5 Gene

Gene Ontology (GO) - Molecular Function for CBWD5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005524 ATP binding IEA --
genes like me logo Genes that share ontologies with CBWD5: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CBWD5 Gene

Localization for CBWD5 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CBWD5 Gene COMPARTMENTS Subcellular localization image for CBWD5 gene
Compartment Confidence
cytosol 2
nucleus 2
peroxisome 2

No data available for Gene Ontology (GO) - Cellular Components for CBWD5 Gene

Pathways for CBWD5 Gene

SuperPathways for CBWD5 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CBWD5 Gene

None

No data available for Pathways by source for CBWD5 Gene

Transcripts for CBWD5 Gene

Unigene Clusters for CBWD5 Gene

COBW domain containing 5:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CBWD5 Gene

No ASD Table

Relevant External Links for CBWD5 Gene

GeneLoc Exon Structure for
CBWD5
ECgene alternative splicing isoforms for
CBWD5

Expression for CBWD5 Gene

mRNA expression in normal human tissues for CBWD5 Gene

SOURCE GeneReport for Unigene cluster for CBWD5 Gene Hs.355950

genes like me logo Genes that share expressions with CBWD5: view

Orthologs for CBWD5 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for CBWD5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CBWD2 37
  • 86 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 37
  • 77 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 79 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Cbwd1 37
  • 71 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 69 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 67 (a)
OneToMany
chicken
(Gallus gallus)
Aves CBWD1 37
  • 63 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 64 (a)
OneToMany
African clawed frog
(Xenopus laevis)
Amphibia Xl.12250 36
zebrafish
(Danio rerio)
Actinopterygii cbwd 37
  • 63 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 37
  • 27 (a)
OneToMany
Species with no ortholog for CBWD5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CBWD5 Gene

ENSEMBL:
Gene Tree for CBWD5 (if available)
TreeFam:
Gene Tree for CBWD5 (if available)

Paralogs for CBWD5 Gene

Paralogs for CBWD5 Gene

Selected SIMAP similar genes for CBWD5 Gene using alignment to 8 proteins:

genes like me logo Genes that share paralogs with CBWD5: view

Variants for CBWD5 Gene

Sequence variations from dbSNP and Humsavar for CBWD5 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs1757262 -- 65,721,929(-) tctag(A/T)gatag intron-variant
rs1757278 -- 65,717,038(-) CCTTA(C/T)ACAAT intron-variant
rs1832104 -- 65,685,769(-) ACATT(C/G/T)GTGAT intron-variant
rs2445987 -- 65,700,114(-) TTAAG(A/G)ATTAT intron-variant
rs2482141 -- 65,700,901(-) ATATT(A/C)AAGCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CBWD5 Gene

Variant ID Type Subtype PubMed ID
dgv2381e1 CNV Complex 17122850
dgv135n16 CNV Deletion 17901297
esv33449 CNV Loss 17666407
essv2899 CNV CNV 17122850
nsv469665 CNV Complex 16826518
dgv2383e1 CNV Complex 17122850
nsv8518 CNV Gain+Loss 18304495

Relevant External Links for CBWD5 Gene

HapMap Linkage Disequilibrium report
CBWD5

Disorders for CBWD5 Gene

No disorders were found for CBWD5 Gene.

No data available for UniProtKB/Swiss-Prot for CBWD5 Gene

Publications for CBWD5 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3

Products for CBWD5 Gene

Sources for CBWD5 Gene

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