CBWD1 Gene
protein-coding GIFtS: 47
GCID: GC09M000121
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COBW domain containing 1
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Aliases
for CBWD1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| COBW Domain Containing 11 2 | | Cobalamin Synthetase W Domain-Containing Protein 12 | | Cobalamin Synthase W Domain-Containing Protein 12 3 | | COBW Domain-Containing Protein 12 | | COBP2 3 | | COBW-Like Protein2 | | NPC-A-6 COBW Domain-Containing Protein 12 3 | | NPC-A-63 |
Export aliases for CBWD1 gene to outside databasesPrevious GC identifers: GC00U991133 GC09M000111 |
Summaries
for CBWD1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Gene Wiki entry for CBWD1
|
Genomic Views
for CBWD1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_008413.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CBWD1 gene promoter:
Pax-6 ATF-2 IRF-7A c-Jun POU3F2 Cdc5 MRF-2 GATA-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CBWD1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CBWD1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9p24.3 Ensembl cytogenetic band: 9p24.3 HGNC cytogenetic band: 9p24.3CBWD1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09M000121: view genomic region
(about GC identifiers)
Start:
|
121,038 bp from pter |
End:
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188,979 bp from pter |
Size:
|
67,942 bases |
Orientation:
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minus strand |
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Proteins
for CBWD1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CBWD1_HUMAN, Q9BRT8 (See
protein sequence)Recommended Name: COBW domain-containing protein 1 Size: 395 amino acids; 44068 Da
Secondary accessions: A2RU55 A8K3N3 B0AZR4 Q49AJ1 Q5VVK2 Q6VBU6 Q7Z5Z0 Q7Z652 Q9BY38 Q9NYD0Alternative splicing: 4 isoforms: Q9BRT8-1 Q9BRT8-2 Q9BRT8-3 Q9BRT8-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CBWD1: NX_Q9BRT8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BRT8
CBWD1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001138827.1 NP_001138828.1 NP_060961.3
ENSEMBL proteins: ENSP00000348915 ENSP00000371885 ENSP00000323433 ENSP00000366666 ENSP00000406064 ENSP00000371830 ENSP00000371826 ENSP00000366617
Human Recombinant Protein Products:
CBWD1 Antibody Products:
Assay Products for CBWD1: |
Protein
Domains /
Families
for CBWD1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CBWD1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9BRT8ProtoNet protein and cluster: Q9BRT8 2 Blocks protein families: IPB003495 Cobalamin synthesis protein/P47K IPB011629 Cobalamin synthesis CobW
UniProtKB/Swiss-Prot: CBWD1_HUMAN, Q9BRT8Similarity: Belongs to the CobW familySimilarity: Contains 1 cobW C-terminal domain |
Function
for CBWD1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CBWD1_HUMAN, Q9BRT8Induction: Increased expression in response to dopamine treatment
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CBWD1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CBWD1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): CBWD1 (NM_018491) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CBWD1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CBWD1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBWD1 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005524 | ATP binding |
IEA | -- |
CBWD1 for ontologies About GeneDecksing
|
Pathways & Interactions
for CBWD1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CBWD1
STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)
5/27 Interacting proteins for CBWD1 (Q9BRT81, 3 ENSP000003489154) via UniProtKB, MINT, STRING, and/or I2D (see all 27)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| METAP1 | P535821, 3, ENSP000002964114 | EBI-1054417,EBI-1051435 I2D:
score=3 STRING: ENSP00000296411 | | GCLM | P485071, 3, ENSP000003592584 | EBI-1054417,EBI-1051387 I2D:
score=1 STRING: ENSP00000359258 | | CNIH4 | Q9P0031, 3, ENSP000004204434 | EBI-1054417,EBI-1044341 I2D:
score=1 STRING: ENSP00000420443 | | SSR4 | P515711, 3, ENSP000003173314 | EBI-1054417,EBI-1054539 I2D:
score=1 STRING: ENSP00000317331 | | ENSG00000258947 | Q135093 | I2D:
score=1 |
About this table
|
Drugs & Compounds
for CBWD1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CBWD1
Search CenterWatch for drugs/clinical trials and news about CBWD1
|
Transcripts
for CBWD1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CBWD1 gene (3 alternative transcripts): NM_001145355.1 NM_001145356.1 NM_018491.3 Unigene Clusters for CBWD1: COBW domain containing 1 Hs.531330 [show with all ESTs], Hs.645337 [show with all ESTs]Unigene Representative Sequences: CR627338, BC06780318/19 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19): ENST00000356521(uc003zgb.4 uc003zga.4 uc003zgc.4) ENST00000475990
ENST00000465380 ENST00000382447 ENST00000465014 ENST00000314367(uc011llr.1)
ENST00000487575 ENST00000464198 ENST00000495302(uc010mgs.3) ENST00000462513
ENST00000475411 ENST00000498044 ENST00000489272 ENST00000377447 ENST00000431099
ENST00000483817 ENST00000382393(uc003zgd.2) ENST00000382389
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CBWD1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CBWD1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): CBWD1 (NM_018491) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CBWD1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CBWD1 |
Additional cDNA sequence: AF265442.1 AK092175.1 AK292585.1 AK293173.1 AK297912.1 AY343911.1 AY344633.1 BC067803.1 BC069006.1 BC082271.1 BC132759.1 BC141856.1 24/63 DOTS entries (see all 63): DT.95115608 DT.121166890 DT.121202301 DT.100890095 DT.99947945 DT.449862 DT.121202407 DT.120971515 DT.95175805 DT.92460248 DT.95175816 DT.121202400 DT.92460279 DT.95175858 DT.100890106 DT.95175886 DT.318244 DT.95175866 DT.100038781 DT.120971500 DT.121166893 DT.100890111 DT.99992243 DT.121166882 24/299 AceView cDNA sequences (see all 299): AA035656 AI628234 CD107464 CR590614 BX415886 AA808637 BC037212 AV708877 AL545680 BC013432 CR591843 AU120141 BU621970 BU628764 AW052189 AA765802 AI469379 AI675600 AA811106 CR609499 AI144241 AW102714 CD368263 BM693807
GeneLoc Exon Structure
|
Expression
for CBWD1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CBWD1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAATAAAAGG
About this image
See CBWD1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CBWD1
SOURCE GeneReport for Unigene clusters: Hs.531330 Hs.645337
UniProtKB/Swiss-Prot: CBWD1_HUMAN, Q9BRT8Tissue specificity: Ubiquitously expressed. Up-regulated in cultured astrocytes treated with dopamine
SABiosciences Custom PCR Arrays for CBWD1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CBWD1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CBWD1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CBWD1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CBWD1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBWD1 |
Orthologs
for CBWD1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for CBWD1 gene from 7/28 species (see all 28) About this table
ENSEMBL Gene Tree for CBWD1 (if available)
TreeFam Gene Tree for CBWD1 (if available) |
Paralogs
for CBWD1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CBWD1 gene
- CBWD22 CBWD62 CBWD32 CBWD72 CBWD52
5 SIMAP similar genes for CBWD1 using alignment to 4 protein entries: CBWD1_HUMAN (see all proteins):CBWD2 CBWD3 CBWD7 CBWD5 CBWD6
CBWD1 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for CBWD1
PGOHUM00000236195
|
Genomic Variants
for CBWD1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CBWD1 (121038 - 188979 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 12 variations for CBWD1
12 CNVs: 8617 31461 2780 3753 37771 52810 82850 95777 34455 8616 52811 65299 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CBWD1 |
|
Disorders
/ Diseases
for CBWD1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CBWD1 for disorders About GeneDecksing
OMIM gene information: 611078
OMIM disorders: --
1  disease for CBWD1: About MalaCardsmalaria
Export disorders for CBWD1 gene to outside databases
|
Publications
for CBWD1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CBWD1 gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with CBWD1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Diverse fates of paralogs following segmental duplication of telomeric genes. (PubMed id 15233989)1, 2, 3 Wong A....Ledbetter D.H. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
- Gene content and function of the ancestral chromosome fusion site in human chromosome 2q13-2q14.1 and paralogous regions. (PubMed id 12421752)1, 3 Fan Y.... Trask B.J. (2002)
- Identification of dopamine responsive mRNAs in glial cells by suppression subtractive hybridization. (PubMed id 11489251)1, 2 Shi J.... Xie Y. (2001)
- Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (2000)
- The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
|
External Searches for CBWD1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CBWD1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CBWD1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CBWD1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CBWD1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CBWD1 gene:
Search GeneIP for patents involving CBWD1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CBWD1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for CBWD1 | | OriGene shRNA RFP for CBWD1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CBWD1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CBWD1 | | | OriGene Protein Over-expression Lysate for CBWD1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CBWD1 | | OriGene 3'-UTR Clone for CBWD1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CBWD1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CBWD1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CBWD1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CBWD1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CBWD1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CBWD1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CBWD1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CBWD1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CBWD1 |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBWD1 |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CBWD1 |
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