Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



CBWD1 Gene

protein-coding   GIFtS: 50
GCID: GC09M000121

COBW Domain Containing 1

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
COBW Domain Containing 11 2     Cobalamin Synthetase W Domain-Containing Protein 12
Cobalamin Synthase W Domain-Containing Protein 12 3     COBW Domain-Containing Protein 12
COBP2 3     COBW-Like Protein2
NPC-A-6 COBW Domain-Containing Protein 12 3     NPC-A-63

External Ids:    HGNC: 171341   Entrez Gene: 558712   Ensembl: ENSG000001727857   OMIM: 6110785   UniProtKB: Q9BRT83   

Export aliases for CBWD1 gene to outside databases

Previous GC identifers: GC00U991133 GC09M000111


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for CBWD1 Gene:
CBWD1 (COBW domain containing 1) is a protein-coding gene. An important paralog of this gene is CBWD2.

Gene Wiki entry for CBWD1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000009.11  NT_008413.19  NC_018920.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CBWD1 gene promoter:
         Pax-6   ATF-2   IRF-7A   c-Jun   POU3F2   Cdc5   MRF-2   GATA-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for CBWD1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CBWD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9p24.3   Ensembl cytogenetic band:  9p24.3   HGNC cytogenetic band: 9p24.3

CBWD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CBWD1 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M000121:  view genomic region     (about GC identifiers)

Start:
121,038 bp from pter      End:
188,979 bp from pter
Size:
67,942 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: CBWD1_HUMAN, Q9BRT8 (See protein sequence)
Recommended Name: COBW domain-containing protein 1  
Size: 395 amino acids; 44068 Da
Secondary accessions: A2RU55 A8K3N3 B0AZR4 Q49AJ1 Q5VVK2 Q6VBU6 Q7Z5Z0 Q7Z652 Q9BY38 Q9NYD0
Alternative splicing: 4 isoforms:  Q9BRT8-1   Q9BRT8-2   Q9BRT8-3   Q9BRT8-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CBWD1: NX_Q9BRT8

Explore proteomics data for CBWD1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys55, Lys69, Lys176, Lys306, Lys370
  • Modification sites at PhosphoSitePlus

  • See CBWD1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001138827.1  NP_001138828.1  NP_060961.3  

    ENSEMBL proteins: 
     ENSP00000348915   ENSP00000371885   ENSP00000323433   ENSP00000366666   ENSP00000406064  
     ENSP00000371830   ENSP00000371826   ENSP00000366617  

    CBWD1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for CBWD1
    OriGene Protein Over-expression Lysate for CBWD1
    OriGene MassSpec for CBWD1
    OriGene Custom Protein Services for CBWD1
    GenScript Custom Purified and Recombinant Proteins Services for CBWD1
    Novus Biologicals CBWD1 Protein
    Novus Biologicals CBWD1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CBWD1

     
    Search eBioscience for Proteins for CBWD1 

     
    antibodies-online proteins for CBWD1 (5 products) 

     
    antibodies-online peptides for CBWD1

    CBWD1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for CBWD1
    OriGene Custom Antibody Services for CBWD1
    Novus Biologicals CBWD1 Antibodies
    Abcam antibodies for CBWD1
    Cloud-Clone Corp. Antibodies for CBWD1
    ThermoFisher Antibodies for CBWD1
    antibodies-online antibodies for CBWD1 (21 products) 

    CBWD1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CBWD1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CBWD1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CBWD1
    Cloud-Clone Corp. CLIAs for CBWD1
    Search eBioscience for ELISAs for CBWD1 
    antibodies-online kits for CBWD1 (6 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    3 InterPro protein domains:
     IPR011629 Cbl_biosynth_CobW-like_C
     IPR027417 P-loop_NTPase
     IPR003495 CobW/HypB/UreG_dom

    Graphical View of Domain Structure for InterPro Entry Q9BRT8

    ProtoNet protein and cluster: Q9BRT8

    2 Blocks protein domains:
    IPB003495 Cobalamin synthesis protein/P47K
    IPB011629 Cobalamin synthesis CobW


    UniProtKB/Swiss-Prot: CBWD1_HUMAN, Q9BRT8
    Similarity: Belongs to the CobW family
    Similarity: Contains 1 cobW C-terminal domain


    Find genes that share domains with CBWD1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CBWD1_HUMAN, Q9BRT8
    Induction: Increased expression in response to dopamine treatment

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005524ATP binding IEA--
         
    Find genes that share ontologies with CBWD1           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for CBWD1

    miRNA
    Products:
        
    miRTarBase miRNAs that target CBWD1:
    hsa-mir-182-3p (MIRT047172), hsa-mir-99a-5p (MIRT048672), hsa-mir-331-3p (MIRT043329)

    Block miRNA regulation of human, mouse, rat CBWD1 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate CBWD1:
    hsa-miR-3611 hsa-miR-3662
    SwitchGear 3'UTR luciferase reporter plasmidCBWD1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CBWD1
    Predesigned siRNA for gene silencing in human, mouse, rat CBWD1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CBWD1

    Clone
    Products:
         
    OriGene clones in human, mouse for CBWD1 (see all 18)
    OriGene ORF clones in mouse, rat for CBWD1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): CBWD1 (NM_018491)
    Sino Biological Human cDNA Clone for CBWD1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CBWD1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CBWD1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for CBWD1
    Browse ESI BIO Cell Lines and PureStem Progenitors for CBWD1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBWD1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    peroxisome1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus




        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CBWD1
    Interactions:

        Search GeneGlobe Interaction Network for CBWD1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    Selected Interacting proteins for CBWD1 (Q9BRT81, 3 ENSP000003489154) via UniProtKB, MINT, STRING, and/or I2D (see all 30)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    METAP1P535821, 3, ENSP000002964114EBI-1054417,EBI-1051435 I2D: score=3 STRING: ENSP00000296411
    GCLMP485071, 3, ENSP000003592584EBI-1054417,EBI-1051387 I2D: score=1 STRING: ENSP00000359258
    CNIH4Q9P0031, 3, ENSP000004204434EBI-1054417,EBI-1044341 I2D: score=1 STRING: ENSP00000420443
    SSR4P515711, 3, ENSP000003173314EBI-1054417,EBI-1054539 I2D: score=1 STRING: ENSP00000317331
    ENSG00000258947Q135093I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CBWD1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for CBWD1 gene (3 alternative transcripts): 
    NM_001145355.1  NM_001145356.1  NM_018491.3  

    Unigene Clusters for CBWD1:

    COBW domain containing 1
    Hs.531330  [show with all ESTs], Hs.645337  [show with all ESTs]
    Unigene Representative Sequences: CR627338, BC067803
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000356521(uc003zgb.4 uc003zga.4 uc003zgc.4) ENST00000475990
    ENST00000382447 ENST00000487575 ENST00000314367(uc011llr.1) ENST00000465014
    ENST00000464198 ENST00000495302(uc010mgs.3) ENST00000462513 ENST00000475411
    ENST00000498044 ENST00000489272 ENST00000377447 ENST00000431099 ENST00000483817
    ENST00000382393(uc003zgd.2) ENST00000382389 ENST00000377400
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CBWD1 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate CBWD1:
    hsa-miR-3611 hsa-miR-3662
    SwitchGear 3'UTR luciferase reporter plasmidCBWD1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CBWD1
    Predesigned siRNA for gene silencing in human, mouse, rat CBWD1
    Clone
    Products:
         
    OriGene clones in human, mouse for CBWD1 (see all 18)
    OriGene ORF clones in mouse, rat for CBWD1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): CBWD1 (NM_018491)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CBWD1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CBWD1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CBWD1
    OriGene qSTAR qPCR primer pairs in human, mouse for CBWD1
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CBWD1
      QuantiTect SYBR Green Assays in human, mouse, rat CBWD1
      QuantiFast Probe-based Assays in human, mouse, rat CBWD1

    Additional mRNA sequence: 

    AF265442.1 AK092175.1 AK292585.1 AK293173.1 AK297912.1 AY343911.1 AY344633.1 BC067803.1 
    BC069006.1 BC082271.1 BC132759.1 BC141856.1 

    Selected DOTS entries (see all 63):

    DT.95115608  DT.121166890  DT.121202301  DT.100890095  DT.99947945  DT.449862  DT.121202407  DT.120971515 
    DT.95175805  DT.92460248  DT.95175816  DT.121202400  DT.92460279  DT.95175858  DT.100890106  DT.95175886 
    DT.318244  DT.95175866  DT.100038781  DT.120971500  DT.121166893  DT.100890111  DT.99992243  DT.121166882 

    Selected AceView cDNA sequences (see all 299):

    BM693807 AA765802 BM720516 BC013432 CR610931 AL531614 AI675600 CR614143 
    CD368263 AW274894 AW052189 AI144241 AI469379 CR609499 AL540640 AW102714 
    BU628764 BM791133 AL545680 BC037212 AI628234 AU120141 AA806479 AA811106 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    CBWD1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAATAAAAGG
    CBWD1 Expression
    About this image

    CBWD1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CBWD1 Protein Expression

    SOURCE GeneReport for Unigene clusters: Hs.531330 Hs.645337

    UniProtKB/Swiss-Prot: CBWD1_HUMAN, Q9BRT8
    Tissue specificity: Ubiquitously expressed. Up-regulated in cultured astrocytes treated with dopamine

        Custom PCR Arrays for CBWD1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for CBWD1
    OriGene qSTAR qPCR primer pairs in human, mouse for CBWD1
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CBWD1
    QuantiTect SYBR Green Assays in human, mouse, rat CBWD1
    QuantiFast Probe-based Assays in human, mouse, rat CBWD1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBWD1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CBWD1 gene from Selected species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cbwd11 , 5 COBW domain containing 11, 5 84.7(n)1
    81.79(a)1
      19 (19.86 cM)5
    2260431  NM_146097.31  NP_666209.11 
     249199165 
    chicken
    (Gallus gallus)
    Aves CBWD11 COBW domain containing 1 74.07(n)
    78.06(a)
      427347  NM_001031436.1  NP_001026607.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    72(a)
    1 → many
    2(49999445-50023007)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia cbwd21 COBW domain containing 2 71.87(n)
    74.72(a)
      496702  NM_001011255.1  NP_001011255.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cbwd1 COBW domain containing 68.93(n)
    74.29(a)
      406536  NM_213253.1  NP_998418.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YNR029C1 YNR029C 52.68(n)
    44.07(a)
      855763   NP_014426.3 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G265201 AT1G26520 53.4(n)
    42.01(a)
      839192  NM_102414.3  NP_173974.3 
    rice
    (Oryza sativa)
    Liliopsida Os.473852 Oryza sativa (japonica cultivar-group) cDNA clone0 more 71.04(n)    AK106521.1 


    ENSEMBL Gene Tree for CBWD1 (if available)
    TreeFam Gene Tree for CBWD1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for CBWD1 gene
    CBWD22  CBWD62  CBWD32  CBWD72  CBWD52  
    5 SIMAP similar genes for CBWD1 using alignment to 4 protein entries:     CBWD1_HUMAN (see all proteins):
    CBWD2    CBWD5    CBWD6    CBWD3    CBWD7

    Find genes that share paralogs with CBWD1           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for CBWD1
    PGOHUM00000236195


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for CBWD1 (see all 989)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs27579661,2
    C,F,O--120568(-) GCGCTA/GGGAAA 3 -- int12Minor allele frequency- G:0.00NA 4
    rs1414669281,2
    --120606(+) AAAAAC/TACAGG 3 -- int10--------
    rs109595101,2
    C,F--120650(+) AAAACT/CCACAT 3 -- int15Minor allele frequency- C:0.44NA CSA 9
    rs22605591,2
    C,F,A,H--120676(-) TTCCCG/ACCTTT 3 -- int110Minor allele frequency- A:0.21NS EA NA WA CSA 429
    rs41263961,2
    --120722(-) aattaG/Tcccag 3 -- int10--------
    rs1433290021,2
    --120831(+) AGGGAA/CAACTG 3 -- int10--------
    rs70221041,2
    C,A--120951(+) CACAGT/AATGAA 3 -- int11Minor allele frequency- A:0.00NA 2
    rs2001025481,2
    C--121206(+) TGTTCA/GGTATA 3 -- ut310--------
    rs1432199821,2
    C--121504(+) TTGTCC/AACTGC 6 /W /L mis11Minor allele frequency- A:0.00NA 4548
    rs1419818931,2
    C,F--121567(+) CTAAAT/ATTCTG 6 /N /I mis11Minor allele frequency- A:0.00EU 1323

    HapMap Linkage Disequilibrium report for CBWD1 (121038 - 188979 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for CBWD1 (see all 20):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2668459CNV Deletion23128226
    esv2674955CNV Deletion23128226
    nsv471465CNV Duplication19718026
    dgv7989n71CNV Loss21882294
    nsv891939CNV Loss21882294
    nsv891943CNV Gain21882294
    esv27644CNV Gain19812545
    dgv7991n71CNV Gain21882294
    dgv253e55CNV Gain17911159
    nsv891940CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CBWD1
    DNA2.0 Custom Variant and Variant Library Synthesis for CBWD1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 611078    OMIM disorders: --


    Find genes that share disorders with CBWD1           About GenesLikeMe


    Export disorders for CBWD1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for CBWD1 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with CBWD1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Diverse fates of paralogs following segmental duplication of telomeric genes. (PubMed id 15233989)1, 2, 3 Wong A.... Ledbetter D.H. (Genomics 2004)
    2. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Gene content and function of the ancestral chromosome fusion site in human chromosome 2q13-2q14.1 and paralogous regions. (PubMed id 12421752)1, 3 Fan Y.... Trask B.J. (Genome Res. 2002)
    5. Identification of dopamine responsive mRNAs in glial cells by suppression subtractive hybridization. (PubMed id 11489251)1, 2 Shi J.... Xie Y. (Brain Res. 2001)
    6. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    7. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (J. Cell. Sci. 2012)
    8. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    9. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    10. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 55871 HGNC: 17134 AceView: LOC55871 Ensembl:ENSG00000172785 euGenes: HUgn55871
    ECgene: CBWD1 H-InvDB: CBWD1

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for CBWD1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for CBWD1 gene:
    Search GeneIP for patents involving CBWD1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for CBWD1   OriGene RNAi products in human, mouse, rat for CBWD1  
     OriGene qPCR primer pairs and template standards for CBWD1   OriGene Protein Over-expression Lysate for CBWD1  
     OriGene MassSpec for CBWD1   OriGene clones in human, mouse for CBWD1  
     OriGene qSTAR qPCR primer pairs in human, mouse for CBWD1   OriGene Purified Protein for CBWD1  
     OriGene ORF clones in mouse, rat for CBWD1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CBWD1   OriGene Custom Protein Services for CBWD1  

     
     
     Block miRNA regulation of human, mouse, rat CBWD1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CBWD1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CBWD1 Predesigned siRNA for gene silencing in human, mouse, rat CBWD1
     QuantiFast Probe-based Assays in human, mouse, rat CBWD1 QuantiTect SYBR Green Assays in human, mouse, rat CBWD1
     Custom PCR Arrays for CBWD1 Search Chromatin IP Primers for CBWD1
     Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CBWD1  Search GeneGlobe Interaction Network for CBWD1
     Regulatory tfbs in CBWD1 promoter
     GenScript Custom Purified and Recombinant Proteins Services for CBWD1 GenScript cDNA clones with any tag delivered in your preferred vector for CBWD1
     GenScript Custom Assay Services for CBWD1 GenScript Custom overexpressing Cell Line Services for CBWD1
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for CBWD1
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for CBWD1
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     CBWD1 antibodies
     CBWD1 proteins
     CBWD1 lysates
     Antibodies for CBWD1
     See all of Abcam's Antibodies, Kits and Proteins for CBWD1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for CBWD1
     Antibodies for CBWD1
     ELISAs for CBWD1
     CLIAs for CBWD1



     Browse ESI BIO Cell Lines and PureStem Progenitors for CBWD1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBWD1
     SwitchGear 3'UTR luciferase reporter plasmids for CBWD1
     Browse SwitchGear Promoter luciferase reporter plasmids for CBWD1
     ThermoFisher Antibodies for CBWD1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CBWD1
     Browse compounds at ApexBio
     Search Addgene for plasmids for CBWD1
      Search eBioscience for proteins for CBWD1
      Search eBioscience for elisas for CBWD1
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for CBWD1
     antibodies-online antibodies for CBWD1 (21 products)
     antibodies-online kits for CBWD1 (6 products)
     antibodies-online peptides for CBWD1
     antibodies-online proteins for CBWD1 (5 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      CBWD1 gene at Home site.
    Version: 3.12.258 10 Dec 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4