Aliases for CBR4 Gene
External Ids for CBR4 Gene
Previous GeneCards Identifiers for CBR4 Gene
GeneCards Summary for CBR4 Gene
CBR4 (Carbonyl Reductase 4) is a Protein Coding gene. Diseases associated with CBR4 include Horner's Syndrome and Autonomic Nervous System Disease. GO annotations related to this gene include oxidoreductase activity and NADPH binding. An important paralog of this gene is DECR2.
UniProtKB/Swiss-Prot for CBR4 Gene
The heteroteramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro).