Aliases for CBR4 Gene
Aliases for CBR4 Gene
- Carbonyl Reductase 4 2 3 5
- 3-Ketoacyl-[Acyl-Carrier-Protein] Reductase Beta Subunit 3 4
- Short Chain Dehydrogenase/Reductase Family 45C Member 1 3 4
- 3-Oxoacyl-[Acyl-Carrier-Protein] Reductase 3 4
- Quinone Reductase CBR4 3 4
- KAR Beta Subunit 3 4
- SDR45C1 3 4
- Short Chain Dehydrogenase/Reductase Family 45C, Member 1 2
External Ids for CBR4 Gene
- HGNC: 25891
- Entrez Gene: 84869
- Ensembl: ENSG00000145439
- UniProtKB: Q8N4T8
Previous GeneCards Identifiers for CBR4 Gene
- GC04M170283
- GC04M170145
- GC04M169815
- GC04M165662
Summaries for CBR4 Gene
GeneCards Summary for CBR4 Gene
CBR4 (Carbonyl Reductase 4) is a Protein Coding gene. Diseases associated with CBR4 include Horner's Syndrome. Among its related pathways are Metabolism and Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha). GO annotations related to this gene include oxidoreductase activity and NADPH binding. An important paralog of this gene is HSD17B8.
UniProtKB/Swiss-Prot for CBR4 Gene
-
The heterotetramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis (PubMed:19571038, PubMed:25203508). Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD (PubMed:25203508). The homotetramer has NADPH-dependent quinone reductase activity (PubMed:19000905). Both homotetramer and the heterotetramer have broad substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro) (PubMed:19000905, PubMed:19571038, PubMed:25203508).
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CBR4 Gene
Genomics for CBR4 Gene
Regulatory Elements for CBR4 Gene
Enhancers for CBR4 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CBR4 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for CBR4 Gene
- Chromosome:
- 4
- Start:
- 168,863,770 bp from pter
- End:
- 169,010,317 bp from pter
- Size:
- 146,548 bases
- Orientation:
- Minus strand
Genomic View for CBR4 Gene
Genes around CBR4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4q32.3 by Ensembl
- 4q32.3 by Entrez Gene
- 4q32.3 by HGNC
CBR4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CBR4 Gene
Proteins for CBR4 Gene
-
Protein details for CBR4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N4T8-CBR4_HUMAN
- Recommended name:
- Carbonyl reductase family member 4
- Protein Accession:
- Q8N4T8
- Q8WTW8
- Q96K93
Protein attributes for CBR4 Gene
- Size:
- 237 amino acids
- Molecular mass:
- 25301 Da
- Quaternary structure:
-
- Homotetramer (in vitro) (PubMed:19000905). Heterotetramer with HSD17B8; contains two molecules each of HSD17B8 and CBR4 (PubMed:19571038, PubMed:25203508). Does not form homotetramers when HSD17B8 is coexpressed, only heterotetramers (in vitro) (PubMed:25203508).
Protein Expression for CBR4 Gene
Selected DME Specific Peptides for CBR4 Gene
- Q8N4T8:
-
- GSIVNVGS
- FLVNAAGINRD
- TGHVLVVDGGLQL
- VNVVAPGF
- GGSRGIG
Post-translational modifications for CBR4 Gene
Other Protein References for CBR4 Gene
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for CBR4
- Novus Biologicals Antibodies for CBR4
- Invitrogen Antibodies for CBR4
- antibodies-online Antibodies for CBR4: See all 37
- GeneTex CBR4 antibody for CBR4
Protein Products
-
OriGene Purified Proteins for CBR4
- Search Origene for MassSpec and Protein Over-expression Lysates for CBR4
- Origene Custom Protein Services for CBR4
- ProSpec Recombinant Proteins for CBR4
- antibodies-online Proteins for CBR4: See all 17
- Search antibodies-online for peptides
- Search GeneTex for Proteins for CBR4
Assay Products
- antibodies-online Kits for CBR4: See all 1
Domains & Families for CBR4 Gene
Gene Families for CBR4 Gene
Protein Domains for CBR4 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CBR4 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8N4T8UniProtKB/Swiss-Prot:
CBR4_HUMAN :- Belongs to the short-chain dehydrogenases/reductases (SDR) family.
- Family:
-
- Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Function for CBR4 Gene
Molecular function for CBR4 Gene
- UniProtKB/Swiss-Prot BiophysicochemicalProperties:
- Kinetic parameters: KM=11 uM for NADPH (for homotetramer) {ECO:0000269 PubMed:19000905}; KM=1.6 uM for 9,10-phenanthrenequinone (for homotetramer) {ECO:0000269 PubMed:19000905}; KM=1.9 uM for 1,4-benzoquinone (for homotetramer) {ECO:0000269 PubMed:19000905}; pH dependence: Optimum pH is 6-8 (for homotetramer). {ECO:0000269 PubMed:19000905};
- UniProtKB/Swiss-Prot Function:
- The heterotetramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis (PubMed:19571038, PubMed:25203508). Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD (PubMed:25203508). The homotetramer has NADPH-dependent quinone reductase activity (PubMed:19000905). Both homotetramer and the heterotetramer have broad substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro) (PubMed:19000905, PubMed:19571038, PubMed:25203508).
Enzyme Numbers (IUBMB) for CBR4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003955 | NAD(P)H dehydrogenase (quinone) activity | IDA | 20837989 |
| GO:0005515 | protein binding | IPI | 19571038 |
| GO:0008753 | NADPH dehydrogenase (quinone) activity | ISS | -- |
| GO:0016491 | oxidoreductase activity | IEA | -- |
| GO:0047025 | 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity | IMP | 25203508 |
Phenotypes for CBR4 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CBR4
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CBR4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CBR4 gene
- Search ViGene Biosciences for CBR4
CRISPR Products
-
OriGene CRISPR knockouts for CBR4
-
Santa Cruz Biotechnology (SCBT) CRISPR for CBR4
- GenScript: Design CRISPR guide RNA sequences for CBR4
miRNA for CBR4 Gene
- miRTarBase miRNAs that target CBR4
miRNA Products
- Search ViGene Biosciences for CBR4
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CBR4
- Browse OriGene Inhibitory RNA Products For CBR4
-
ViGene Biosciences ready-to-package AAV shRNAs for CBR4 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CBR4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CBR4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CBR4
-
ViGene Biosciences adenoviral particle packaged cDNA for CBR4 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CBR4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CBR4 gene
Flow Cytometry Products
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CBR4 Gene
Localization for CBR4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CBR4 Gene
- Mitochondrion matrix.
| Compartment | Confidence |
|---|---|
| mitochondrion | 5 |
| cytosol | 2 |
| plasma membrane | 1 |
| nucleus | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005739 | mitochondrion | IEA | -- |
| GO:0005759 | mitochondrial matrix | TAS | -- |
| GO:1990204 | oxidoreductase complex | IMP | 25203508 |
Pathways & Interactions for CBR4 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Metabolism |
.37
|
|
| 2 | Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | ||
Pathways by source for CBR4 Gene
3 Reactome pathways for CBR4 Gene
UniProtKB/Swiss-Prot Q8N4T8-CBR4_HUMAN
- Pathway: Lipid metabolism; fatty acid biosynthesis.
Interacting Proteins for CBR4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006629 | lipid metabolic process | IEA | -- |
| GO:0006631 | fatty acid metabolic process | IEA | -- |
| GO:0006633 | fatty acid biosynthetic process | IMP | 25203508 |
| GO:0044255 | cellular lipid metabolic process | TAS | -- |
| GO:0044597 | daunorubicin metabolic process | IMP | 20837989 |
No data available for SIGNOR curated interactions for CBR4 Gene
Transcripts for CBR4 Gene
mRNA/cDNA for CBR4 Gene
- (9) REFSEQ mRNAs :
- (6) Additional mRNA sequences :
- (80) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for CBR4
-
Santa Cruz Biotechnology (SCBT) CRISPR for CBR4
- GenScript: Design CRISPR guide RNA sequences for CBR4
miRNA Products
- Search ViGene Biosciences for CBR4
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CBR4
- Browse OriGene Inhibitory RNA Products For CBR4
-
ViGene Biosciences ready-to-package AAV shRNAs for CBR4 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CBR4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CBR4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | ^ | 8a | · | 8b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | |||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||||||||
| SP5: | - | - | - | ||||||||||||||||||||||||||||
| SP6: | - | - | |||||||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - |
Expression for CBR4 Gene
This gene is overexpressed in Liver (6.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CBR4 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of CBR4 Gene:
CBR4SOURCE GeneReport for Unigene cluster for CBR4 Gene:
Hs.659311mRNA Expression by UniProt/SwissProt for CBR4 Gene:
Q8N4T8-CBR4_HUMAN
Tissue specificity:
Detected in liver and kidney (at protein level).
Evidence on tissue expression from TISSUES for CBR4 Gene
- Liver(4.3)
- Intestine(4.2)
- Nervous system(3.1)
Primer Products
-
OriGene qPCR primer pairs and template standards for CBR4
-
OriGene qPCR primer pairs for CBR4
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for CBR4 Gene
Orthologs for CBR4 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CBR4 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | CBR4 35 |
|
OneToOne | |
| LOC477352 34 |
|
||||
| platypus (Ornithorhynchus anatinus) |
Mammalia | CBR4 35 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Cbr4 34 16 35 |
|
||
| cow (Bos Taurus) |
Mammalia | CBR4 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Cbr4 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | CBR4 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CBR4 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | CBR4 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | cbr4 34 |
|
||
| Str.15559 34 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.11545 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | cbr4 34 35 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | AT1G24360 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os12g0242700 34 |
|
||
| bread mold (Neurospora crassa) |
Ascomycetes | NCU03525 34 |
|
||
| fission yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | oar2 34 |
|
- Species where no ortholog for CBR4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for CBR4 Gene
Paralogs for CBR4 Gene
(9) SIMAP similar genes for CBR4 Gene using alignment to 5 proteins:
Variants for CBR4 Gene
| SNP ID | Clin | Chr 04 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs112116419 | Likely benign | 168,925,229(+) | TATTT(A/G)TAGTT | intron-variant | |
| rs113515140 | Likely benign | 168,926,209(+) | TCTTT(A/G)TAGCC | intron-variant | |
| rs113676921 | Likely benign | 168,898,684(+) | TTCAC(A/C/G)TGTAG | intron-variant, reference, synonymous-codon | |
| rs113794451 | Likely benign | 168,926,672(+) | AATCA(A/G)TTGTT | intron-variant, utr-variant-3-prime | |
| rs114171764 | Likely benign | 168,915,900(+) | GCCTC(A/G)TTCTA | intron-variant, reference, missense |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv34043 | CNV | loss | 18971310 |
| nsv1026854 | CNV | gain | 25217958 |
Residual Variation Intolerance Score:
41.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.66;
31.76% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CBR4 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CBR4 Gene
Disorders for CBR4 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| horner's syndrome |
|
|
Search CBR4 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for CBR4
No data available for UniProtKB/Swiss-Prot and Genatlas for CBR4 Gene
Publications for CBR4 Gene
- Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase. (PMID: 25203508) Venkatesan R. … Chen Z. (Nat. Commun. 2014) 3 4 64
- Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3 46 64
- The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. (PMID: 19027726) Persson B. … Oppermann U. (Chem. Biol. Interact. 2009) 2 3 64
- 17beta-Hydroxysteroid dehydrogenase type 8 and carbonyl reductase type 4 assemble as a ketoacyl reductase of human mitochondrial FAS. (PMID: 19571038) Chen Z. … Hiltunen J.K. (FASEB J. 2009) 3 4 64
- Human carbonyl reductase 4 is a mitochondrial NADPH-dependent quinone reductase. (PMID: 19000905) Endo S. … Hara A. (Biochem. Biophys. Res. Commun. 2008) 3 4 64
Products for CBR4 Gene
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- Custom Antibody ServicesOriGene Antibodies for CBR4
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- OriGene qPCR primer pairs and template standards for CBR4
- OriGene qPCR primer pairs for CBR4
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- GenScript: Next-day shipping cDNA ORF clone for CBR4 in any vector
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- GenScript: Design CRISPR guide RNA sequences for CBR4
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for CBR4
- Novus Biologicals proteins and lysates for CBR4
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ProSpec Recombinant Proteins for CBR4
- antibodies-online Antibodies for CBR4: See all 37
- antibodies-online Kits for CBR4: See all 1
- antibodies-online Proteins for CBR4: See all 17
- Search antibodies-online for peptides
- GeneTex CBR4 antibody for CBR4
- Search GeneTex for Proteins for CBR4
- ViGene Biosciences adenoviral particle packaged cDNA for CBR4 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CBR4 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CBR4 gene
- Search ViGene Biosciences for CBR4
- Horizon Cell Lines for CBR4
- Cyagen custom Knockout/knockin (KOKI) mouse models for CBR4
- VectorBuilder custom plasmid, inducible vectors for CBR4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CBR4
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CBR4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
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