CBR3-AS1 Gene
RNA gene GIFtS : 21
GCID: GC21 M037506
CBR3 antisense RNA 1 (Previous name: CBR3 antisense RNA 1 (non-protein coding) )
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Aliasesfor CBR3-AS1 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Subcategory (RNA class): lncRNAQuality score for this RNA gene is 5 Aliases CBR3 Antisense RNA 1 1 2 PlncRNA-11 2 CBR3 Antisense RNA 1 (Non-Protein Coding)1
External Ids: HGNC: 43664 1 Entrez Gene: 100506428 2 Ensembl: ENSG00000236830 7 Export aliases for CBR3-AS1 gene to outside databases
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Summariesfor CBR3-AS1 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section fRNAdb sequence ontology for CBR3-AS1: antisense_RNA - Antisense RNA is RNA that is transcribed from the coding, rather than the template, strand of DNA. It is therefore complementary to mRNA.View fRNAdb secondary structures for CBR3-AS1
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Genomic Viewsfor CBR3-AS1 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000021.8 NC_018932.1 NT_011512.11 Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for CBR3-AS1 Other transcription factors Search SABiosciences Chromatin IP Primers for CBR3-AS1 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CBR3-AS1
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Ensembl cytogenetic band: 21q22.12 HGNC cytogenetic band: 21q22.12 CBR3-AS1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 21 GeneLoc Exon Structure
GeneLoc location for GC21M037506: view genomic region
(about GC identifiers )
Start:
37,504,065 bp from pter
End:
37,528,605 bp from pter
Size:
24,541 bases
Orientation:
minus strand
ORGUL member locations:Legend (see complete legend)
FR0088521
n378251
n378411
FR0168790
37513693 37521149 37528604 chr21
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Proteinsfor CBR3-AS1 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB: --
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Protein
Domains / Familiesfor CBR3-AS1 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Functionfor CBR3-AS1 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section
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Pathways & Interactionsfor CBR3-AS1 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CBR3-AS1
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Drugs & Compoundsfor CBR3-AS1 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for CBR3-AS1 Search CenterWatch for drugs/clinical trials and news about CBR3-AS1
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Transcriptsfor CBR3-AS1 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section 1 fRNAdb Secondary structure: Unigene Cluster for CBR3-AS1:
CBR3 antisense RNA 1 Hs.651214 [show with all ESTs ] Unigene Representative Sequence: BC037580 4 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000453159(lincRNA) (uc002yvd.2 ) ENST00000413862(lincRNA) (uc002yvc.2 ) ENST00000427491(lincRNA) (uc002yvf.2 )ENST00000432988(lincRNA) Additional cDNA sequence: AB004851.1 BC037580.1 BC047014.1 NR_038892.1 NR_038893.1 NR_038894.1
6 DOTS entries : DT.100757941 DT.439617 DT.100744030 DT.100675933 DT.429473 DT.435430 GeneLoc Exon Structure
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Expression for CBR3-AS1 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section Expression evidence for CBR3-AS1:none
CBR3-AS1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: GGTAGTAATT
About this image Genevestigator expression for CBR3-AS1 SOURCE GeneReport for Unigene cluster: Hs.651214 SABiosciences Custom PCR Arrays for CBR3-AS1 Primer Products: Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat CBR3-AS1 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CBR3-AS1 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CBR3-AS1
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Orthologsfor CBR3-AS1 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
--
ENSEMBL Gene Tree for CBR3-AS1 (if available)TreeFam Gene Tree for CBR3-AS1 (if available)
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Paralogsfor CBR3-AS1 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section --
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Genomic Variantsfor CBR3-AS1 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 21 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for CBR3-AS1 (37504065 - 37528605 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for CBR3-AS1: --
SABiosciences Cancer Mutation PCR Assays
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Disorders
/ Diseasesfor CBR3-AS1 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
CBR3-AS1 for disorders About GeneDecksing OMIM gene information: 603608 2 diseases for CBR3-AS1 : About MalaCards prostate cancer prostatitis Export disorders for CBR3-AS1 gene to outside databases
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Publicationsfor CBR3-AS1 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for CBR3-AS1 gene integrated from 9 sources : (articles sorted by number of sources associating them with CBR3-AS1) Utopia : connect your pdf to the dynamic world of online information
The prostate cancer-up-regulated long noncoding RNA P lncRNA-1 modulates apoptosis and proliferation through reciprocal regulation of androgen receptor. (PubMed id 22264502) 1 , 3 Cui Z....Sun Y. (2012) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002) Mapping of a novel human carbonyl reductase, CBR3, and ribosomal pseudogenes to human chromosome 21q22.2. (PubMed id 9740676) 1 Watanabe K.... Nomura T. (1998) (PubMed id 15608161) 10
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External Searches for CBR3-AS1 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing CBR3-AS1 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing CBR3-AS1 gene
(According to HUGE )
About This Section --
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Specialized Databases showing CBR3-AS1 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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About This Section Patent Information for CBR3-AS1 gene: Search GeneIP for patents involving CBR3-AS1 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor CBR3-AS1 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CBR3-AS1 Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CBR3-AS1 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CBR3-AS1 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat CBR3-AS1 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CBR3-AS1 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CBR3-AS1
Search ThermoFisher Antibodies for CBR3-AS1
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CBR3-AS1
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Genomic Views for CBR3-AS1
Intellectual Property for CBR3-AS1
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