Aliases for CBR3 Gene
External Ids for CBR3 Gene
Previous GeneCards Identifiers for CBR3 Gene
Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq, Jul 2008]
GeneCards Summary for CBR3 Gene
CBR3 (Carbonyl Reductase 3) is a Protein Coding gene. Among its related pathways are Doxorubicin Pathway (Cardiomyocyte Cell), Pharmacodynamics and Metabolism. GO annotations related to this gene include oxidoreductase activity and carbonyl reductase (NADPH) activity. An important paralog of this gene is CBR1.
UniProtKB/Swiss-Prot for CBR3 Gene
Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro).