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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

CBLN4 Gene

protein-coding GIFtS: 49
GCID: GC20M054572

cerebellin 4 precursor

(Previous name: cerebellin precursor-like 1 )
(Previous symbol: CBLNL1)

Explore 1 disease affiliated with
CBLN4 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Cerebellin 4 Precursor¹ ²
CBLNL1¹ ² ³
Cerebellin Precursor-Like 1¹ ²
Cerebellin-Like Glycoprotein 1² ³
DJ885A10.1¹
Cerebellin-4¹

External Ids:	HGNC: 16231¹	Entrez Gene: 140689²	Ensembl: ENSG00000054803⁷	OMIM: 615029⁵	UniProtKB: Q9NTU7³

Export aliases for CBLN4 gene to outside databases

Previous GC identifers: GC20M054005 GC20M051353

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CBLN4:

This gene encodes a member of a family of small secreted proteins containing C1Q domains. Members of this family are

involved in regulation of neurexin signalling during synapse development. The mouse homolog of the protein encoded by

this gene competes with netrin to bind to the deleted in colorectal cancer receptor. (provided by RefSeq, Aug 2012)

UniProtKB/Swiss-Prot: CBLN4_HUMAN, Q9NTU7

Function: May be involved in synaptic functions in the CNS. Can enable ER export and secretion of CBLN3 (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000020.10 NC_018931.1 NT_011362.10

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the CBLN4 gene promoter:
TBP Bach1 p53 Nkx2-5 Tal-1beta GATA-1 Arnt FAC1 Nkx6-1 ITF-2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CBLN4 promoter sequence

Search SABiosciences Chromatin IP Primers for CBLN4

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CBLN4

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13 Ensembl cytogenetic band: 20q13.2 HGNC cytogenetic band: 20q13

CBLN4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CBLN4 gene location

GeneLoc information about chromosome 20 GeneLoc Exon Structure

GeneLoc location for GC20M054572: view genomic region (about GC identifiers)

Start:	54,572,496 bp from pter	End:	54,580,528 bp from pter
Size:	8,033 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CBLN4_HUMAN, Q9NTU7 (See protein sequence)

Recommended Name: Cerebellin-4 precursor

Size: 201 amino acids; 21808 Da

Subunit: Homohexamer; disulfide-linked homotrimers. The trimers are assembled via the globular C1q domains. The trimers

associate via N-terminal cysteine residues to form disulfide-linked hexamers. May interact with CBLN1, CBLN2 and CBLN3

(By similarity)

Subcellular location: Secreted (By similarity). Cell junction, synapse (By similarity)

Explore the universe of human proteins at neXtProt for CBLN4: NX_Q9NTU7

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9NTU7

CBLN4 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_542184.1

ENSEMBL proteins:

ENSP00000064571

Human Recombinant Protein Products:

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	Uscn Proteins for CBLN4

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005615	extracellular space	IEA	--
GO:0030054	cell junction	IEA	--
GO:0045202	synapse	IEA	--

CBLN4 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for CBLN4

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CBLN4 for domains About GeneDecksing

2 InterPro domains/families:

IPR008983 Tumour_necrosis_fac-like_dom

IPR001073 C1q

Graphical View of Domain Structure for InterPro Entry Q9NTU7

ProtoNet protein and cluster: Q9NTU7

1 Blocks protein family: IPB001073 Complement C1q protein

UniProtKB/Swiss-Prot: CBLN4_HUMAN, Q9NTU7

Similarity: Contains 1 C1q domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: CBLN4_HUMAN, Q9NTU7

Function: May be involved in synaptic functions in the CNS. Can enable ER export and secretion of CBLN3 (By similarity)

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CBLN4
		8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate CBLN4 (see all 13):
		hsa-miR-3910 hsa-miR-26a-2* hsa-miR-92a hsa-miR-367 hsa-miR-25 hsa-miR-32 hsa-miR-548aa hsa-miR-124

		SwitchGear 3'UTR luciferase reporter plasmid: CBLN4 3' UTR sequence

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Gene Editing
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		Search LifeMap BioReagents cell lines for CBLN4

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBLN4

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	--	--

CBLN4 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for CBLN4:

Synthetic lethal with Ras

Animal Models:
Mouse knock-outs for CBLN4: Cbln4^tm1Jim Cbln4^tm1Lex
1 MGI mutant phenotype (inferred from 2 alleles) (MGI details for Cbln4):

normal

CBLN4 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for CBLN4

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for CBLN4 (Q9NTU7³ ENSP00000064571⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CBLN3	Q6UW01³, ENSP00000267406⁴	I2D: score=1 STRING: ENSP00000267406

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0009306	protein secretion	IEA	--

CBLN4 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CBLN4
Search CenterWatch for drugs/clinical trials and news about CBLN4

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CBLN4 gene:

NM_080617.5

Unigene Clusters for CBLN4:

Cerebellin 4 precursor

Hs.126141 [show with all ESTs], Hs.741877 [show with all ESTs]

Unigene Representative Sequences: BC047076, NM_080617

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000064571(uc002xxa.3)

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CBLN4
		8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate CBLN4 (see all 13):
		hsa-miR-3910 hsa-miR-26a-2* hsa-miR-92a hsa-miR-367 hsa-miR-25 hsa-miR-32 hsa-miR-548aa hsa-miR-124

		SwitchGear 3'UTR luciferase reporter plasmid: CBLN4 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CBLN4 (see all 7) OriGene shRNA RFP: CBLN4 OriGene siRNA: CBLN4
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CBLN4

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CBLN4 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CBLN4 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: CBLN4 (NM_080617)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for CBLN4
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CBLN4

Additional cDNA sequence:

AK289640.1 AY358527.1 BC050026.1 BC069402.1 BC069488.1 BC069516.1

1 DOTS entry:

DT.97797762

23 AceView cDNA sequences:

NM_080617 BC069402 BC069488 BC069516 AY358527 BX093493 AV722278 BC047076

BQ722274 AA868507 BX506987 BC050026 BF445600 BI668562 AW074518 BG704824

CD244520 CA397204 AV721267 AI468259 BU781883 AL044686 BI669085

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CBLN4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACCACTTTAT

About this image

CBLN4 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

8 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Testis

Kidney

Kidney

Kidney

Kidney

Kidney

Testis

Testis

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See CBLN4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CBLN4

SOURCE GeneReport for Unigene clusters: Hs.126141 Hs.741877

SABiosciences Custom PCR Arrays for CBLN4

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CBLN4

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBLN4

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for CBLN4 gene from 5/13 species (see all 13) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Cbln4^{1 , 5}	cerebellin 4 precursor protein^{1, 5}	88.89(n)¹ 97.47(a)¹		2 (94.74 cM)⁵ 228942¹ NM_175631.3¹ NP_783439.1¹ 172036233⁵
chicken (Gallus gallus)	Aves	CBLN4¹	cerebellin 4 precursor	86.91(n) 93.72(a)		769254 NM_001079487.1 NP_001072955.1
lizard (Anolis carolinensis)	Reptilia	CBLN4⁶	--	86(a)	1 ↔ 1	GL343217.1(2382820-2408958)
African clawed frog (Xenopus laevis)	Amphibia	MGC64424²	hypothetical protein MGC64424	78.79(n)		BC056851.1
zebrafish (Danio rerio)	Actinopterygii	cbln4¹	cerebellin 4 precursor	76.6(n) 89.36(a)		563847 NM_001110391.1 NP_001103861.1

ENSEMBL Gene Tree for CBLN4 (if available)
TreeFam Gene Tree for CBLN4 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for CBLN4 gene

CBLN2² CBLN1² CAPRIN1² CBLN3² CAPRIN2²

4 SIMAP similar genes for CBLN4 using alignment to 1 protein entry: CBLN4_HUMAN:

CBLN2 CBLN1 CBLN3 CAPRIN2

CBLN4 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 20 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs186136654^1,2		--	54572008(+)	`TCCTAA/CGAAGA`	1	--	ds500¹		0	--	--	--	--
rs143349148^1,2		--	54572015(+)	`AAGAGA/GCCTGC`	1	--	ds500¹		0	--	--	--	--
rs146716452^1,2		--	54572062(+)	`AGAACG/TTTTCC`	1	--	ds500¹		0	--	--	--	--
rs6014571^1,2	C,F,A,H,	--	54572086(+)	`TATGAG/AAATAT`	1	--	ds500¹		20		NS EA NA WA CSA	1632
rs189178053^1,2		--	54572234(+)	`AGCTCA/GCAATT`	1	--	ds500¹		0	--	--	--	--
rs59874171^1,2	F,	--	54572270(+)	`GTAAAG/TATTTC`	1	--	ds500¹		2		NA EA	240
rs140421294^1,2		--	54572271(+)	`TAAAGA/GTTTCC`	1	--	ds500¹		0	--	--	--	--
rs180702272^1,2		--	54572280(+)	`CCTATA/GTCAGC`	1	--	ds500¹		0	--	--	--	--
rs143581593^1,2		--	54572464(+)	`ACATAC/TTTCCA`	1	--	ut3¹		0	--	--	--	--
rs185905240^1,2		--	54572484(+)	`GAAAAA/GAACAA`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for CBLN4 (54572496 - 54580528 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CBLN4: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CBLN4

DNA2.0 Custom Variant and Variant Library Synthesis for CBLN4

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CBLN4 for disorders           About GeneDecksing

OMIM gene information: 615029    OMIM disorders: --

1 disease for CBLN4:    About MalaCards

colorectal cancer

Export disorders for CBLN4 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for CBLN4 gene, integrated from 9 sources (see all 15):
(articles sorted by number of sources associating them with CBLN4)

Utopia: connect your pdf to the dynamic
world of online information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)^{1, 2} Zhang Z. and Henzel W.J. (2004)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)^{1, 2} Deloukas P....Rogers J. (2001)
Precerebellin-related genes and precerebellin 1 peptide in the adrenal gland of the rat: expression pattern, localization, developmental regulation and effects on corticosteroidogenesis. (PubMed id 19212655)^{1, 9} Rucinski M....Malendowicz L.K. (2009)
Glutamate receptor d1 induces preferentially inhibitor y presynaptic differentiation of cortical neurons by interacting with neurexins through cerebellin precursor protein subtypes. (PubMed id 22191730)¹ Yasumura M....Mishina M. (2012)
The Cbln family of proteins interact with multiple sig naling pathways. (PubMed id 22220752)¹ Wei P....Morgan J.I. (2012)
Differential interactions of cerebellin precursor prot ein (Cbln) subtypes and neurexin variants for synapse formation of cortical neur ons. (PubMed id 21356198)¹ Joo J.Y....Mishina M. (2011)
Cbln family proteins promote synapse formation by regu lating distinct neurexin signaling pathways in various brain regions. (PubMed id 21410790)¹ Matsuda K. and Yuzaki M. (2011)
Cbln and C1q family proteins: new transneuronal cytoki nes. (PubMed id 18278437)¹ Yuzaki M. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 140689	HGNC: 16231	AceView: CBLN4	Ensembl:ENSG00000054803	euGenes: HUgn140689
ECgene: CBLN4	H-InvDB: CBLN4

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for CBLN4	Pharmacogenomics, SNPs, Pathways

Intellectual Property for CBLN4 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for CBLN4 gene:
Search GeneIP for patents involving CBLN4

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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	Antibodies for CBLN4 (Cerebellin-4)		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
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	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for CBLN4
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CBLN4		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CBLN4
	OriGene Protein Over-expression Lysate for CBLN4		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for CBLN4		Browse 3'-UTR reporter clones for miRNA target validation
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CBLN4		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CBLN4
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for CBLN4		OriGene Custom Protein Services for CBLN4
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CBLN4
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CBLN4
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CBLN4
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CBLN4
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CBLN4
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CBLN4

	GenScript Custom Purified and Recombinant Proteins Services for CBLN4		GenScript cDNA clones with any tag delivered in your preferred vector for CBLN4
	GenScript Custom Assay Services for CBLN4		GenScript Custom Superior Antibodies Services for CBLN4
	GenScript Custom overexpressing Cell Line Services for CBLN4		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

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	Regulatory tfbs in CBLN4 promoter
	Search Chromatin IP Primers for CBLN4
	RT² qPCR Primer Assay in human, mouse, rat CBLN4
	Search GNC Networks for CBLN4
	SABiosciences Custom PCR Arrays for CBLN4

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	Browse Sino Biological Proteins and Antibodies
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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	CBLN4 antibodies
	CBLN4 proteins

	Search for Antibodies for CBLN4 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for CBLN4
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Browse ProSpec Recombinant Proteins

CBLN4 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for CBLN4

	Gene Synthesis
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBLN4

	SwitchGear 3'UTR luciferase reporter plasmids for CBLN4
	SwitchGear Promoter luciferase reporter plasmids for CBLN4

ThermoFisher Antibodies for CBLN4

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CBLN4

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes CBLN4 gene at Home site.

hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4

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Export list of displayed genes

CBLN4 Gene

cerebellin 4 precursor

Aliases
for CBLN4 gene

Summaries
for CBLN4 gene

Genomic Views
for CBLN4 gene

Proteins
for CBLN4 gene

Protein Domains /
Families
for CBLN4 gene

Function
for CBLN4 gene

Pathways & Interactions
for CBLN4 gene

Drugs & Compounds
for CBLN4 gene

Transcripts
for CBLN4 gene

Expression
for CBLN4 gene

Orthologs
for CBLN4 gene

Paralogs
for CBLN4 gene

Genomic Variants
for CBLN4 gene

Disorders / Diseases
for CBLN4 gene

Publications
for CBLN4 gene

External Searches for CBLN4 gene

Genome Databases showing CBLN4 gene

Other Databases showing CBLN4 gene

Specialized Databases showing CBLN4 gene

Intellectual Property
for CBLN4 gene

Products
for CBLN4 gene

View Random Gene

Advanced Search

Export list of displayed genes

CBLN4 Gene

cerebellin 4 precursor

Aliasesfor CBLN4 gene

Summariesfor CBLN4 gene

Genomic Viewsfor CBLN4 gene

Proteinsfor CBLN4 gene

Protein Domains /Familiesfor CBLN4 gene

Functionfor CBLN4 gene

Pathways & Interactionsfor CBLN4 gene

Drugs & Compoundsfor CBLN4 gene

Transcriptsfor CBLN4 gene

Expression for CBLN4 gene

Orthologsfor CBLN4 gene

Paralogsfor CBLN4 gene

Genomic Variantsfor CBLN4 gene

Disorders / Diseasesfor CBLN4 gene

Publicationsfor CBLN4 gene

External Searches for CBLN4 gene

Genome Databases showing CBLN4 gene

Other Databases showing CBLN4 gene

Specialized Databases showing CBLN4 gene

Intellectual Propertyfor CBLN4 gene

Productsfor CBLN4 gene

View Random Gene

Aliases
for CBLN4 gene

Summaries
for CBLN4 gene

Genomic Views
for CBLN4 gene

Proteins
for CBLN4 gene

Protein Domains /
Families
for CBLN4 gene

Function
for CBLN4 gene

Pathways & Interactions
for CBLN4 gene

Drugs & Compounds
for CBLN4 gene

Transcripts
for CBLN4 gene

Expression
for CBLN4 gene

Orthologs
for CBLN4 gene

Paralogs
for CBLN4 gene

Genomic Variants
for CBLN4 gene

Disorders / Diseases
for CBLN4 gene

Publications
for CBLN4 gene

Intellectual Property
for CBLN4 gene

Products
for CBLN4 gene