Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



CBLN3 Gene

protein-coding   GIFtS: 44
GCID: GC14M024895

Cerebellin 3 Precursor

  See CBLN3-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Cerebellin 3 Precursor1 2
PRO14862
cerebellin-32

External Ids:    HGNC: 201461   Entrez Gene: 6438662   Ensembl: ENSG000001398997   OMIM: 6129785   UniProtKB: Q6UW013   

Export aliases for CBLN3 gene to outside databases

Previous GC identifers: GC00U907483 GC14U900191 GC14M023967 GC14M005010


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for CBLN3 Gene:
Members of the precerebellin family, such as CBLN3, contain a cerebellin motif (see CBLN1; MIM 600432) and a
C-terminal C1q signature domain (see MIM 120550) that mediates trimeric assembly of atypical collagen complexes.
However, precerebellins do not contain a collagen motif, suggesting that they are not conventional components of
the extracellular matrix (Pang et al., 2000 (PubMed 10964938)).(supplied by OMIM, Aug 2009)

GeneCards Summary for CBLN3 Gene:
CBLN3 (cerebellin 3 precursor) is a protein-coding gene. Diseases associated with CBLN3 include spinocerebellar degeneration, and olivopontocerebellar atrophy. An important paralog of this gene is CBLN2.

UniProtKB/Swiss-Prot: CBLN3_HUMAN, Q6UW01
Function: May be involved in synaptic functions in the CNS (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NC_018925.2  NT_026437.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the CBLN3 gene promoter:
         AREB6   Tal-1   ITF-2   Tal-1beta   ATF6   E47   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for CBLN3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CBLN3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q12   Ensembl cytogenetic band:  14q12   HGNC cytogenetic band: 14q12

CBLN3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CBLN3 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M024895:  view genomic region     (about GC identifiers)

Start:
24,895,738 bp from pter      End:
24,900,160 bp from pter
Size:
4,423 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: CBLN3_HUMAN, Q6UW01 (See protein sequence)
Recommended Name: Cerebellin-3 precursor  
Size: 205 amino acids; 21521 Da
Subunit: Heterohexamer; disulfide-linked heterotrimers. Interacts with CBLN1. May also form oligomers with CBLN2
AND CBLN4 (By similarity)

Explore the universe of human proteins at neXtProt for CBLN3: NX_Q6UW01

Explore proteomics data for CBLN3 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn90
  • Modification sites at PhosphoSitePlus

  • See CBLN3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001034860.1  
    ENSEMBL proteins: 
     ENSP00000267406   ENSP00000450935  

    CBLN3 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Enzo Life Sciences proteins for CBLN3
    OriGene Purified Protein for CBLN3
    OriGene Protein Over-expression Lysate for CBLN3
    OriGene MassSpec for CBLN3
    OriGene Custom Protein Services for CBLN3
    GenScript Custom Purified and Recombinant Proteins Services for CBLN3
    Novus Biologicals CBLN3 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CBLN3

     
    Search eBioscience for Proteins for CBLN3 

    CBLN3 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for CBLN3
    OriGene Custom Antibody Services for CBLN3
    Novus Biologicals CBLN3 Antibodies
    Abcam antibodies for CBLN3 (P23435, Q6UW01)
    Cloud-Clone Corp. Antibodies for CBLN3
    Search ThermoFisher Antibodies for CBLN3
    LSBio Antibodies in human, mouse, rat for CBLN3

    CBLN3 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CBLN3
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CBLN3
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CBLN3
    Cloud-Clone Corp. CLIAs for CBLN3
    Search eBioscience for ELISAs for CBLN3 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    2 InterPro protein domains:
     IPR008983 Tumour_necrosis_fac-like_dom
     IPR001073 C1q

    Graphical View of Domain Structure for InterPro Entry Q6UW01

    ProtoNet protein and cluster: Q6UW01

    1 Blocks protein domain: IPB001073 Complement C1q protein

    UniProtKB/Swiss-Prot: CBLN3_HUMAN, Q6UW01
    Similarity: Contains 1 C1q domain


    Find genes that share domains with CBLN3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CBLN3_HUMAN, Q6UW01
    Function: May be involved in synaptic functions in the CNS (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with CBLN3           About GenesLikeMe


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Cbln3):
     behavior/neurological  nervous system  normal 

    Find genes that share phenotypes with CBLN3           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Cbln3tm1Jim for CBLN3

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CBLN3
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CBLN3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CBLN3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CBLN3

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat CBLN3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CBLN3 (see all 13):
    hsa-miR-596 hsa-miR-513a-5p hsa-miR-1271 hsa-miR-3155 hsa-miR-1205 hsa-miR-609 hsa-miR-484 hsa-miR-214*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CBLN3
    Predesigned siRNA for gene silencing in human, mouse, rat CBLN3

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CBLN3

    Clone
    Products:
         
    OriGene clones in human, mouse for CBLN3 (see all 6)
    OriGene ORF clones in mouse, rat for CBLN3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CBLN3 (NM_001039771)
    Sino Biological Human cDNA Clone for CBLN3
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CBLN3
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CBLN3

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for CBLN3
    Browse ESI BIO Cell Lines and PureStem Progenitors for CBLN3 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBLN3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    CBLN3_HUMAN, Q6UW01: Endoplasmic reticulum (By similarity). Golgi apparatus, cis-Golgi network (By similarity).
    Secreted (By similarity). Cell junction, synapse (By similarity). Note=In the absence of CBLN1, remains in the
    endoplasmic reticulum/cis-Golgi apparatus. Partial secretion depends on a association with CBLN1 and maybe CBLN4,
    but not on CBLN2 (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular3
    golgi apparatus3
    endoplasmic reticulum2
    cytosol1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IEA--
    GO:0005783endoplasmic reticulum IEA--
    GO:0005794Golgi apparatus IEA--
    GO:0030054cell junction IEA--
    GO:0045202synapse IEA--

    Find genes that share ontologies with CBLN3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus




        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CBLN3
    Interactions:

        Search GeneGlobe Interaction Network for CBLN3

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for CBLN3 (Q6UW013 ENSP000002674064) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CBLN2Q8IUK83, ENSP000002695034I2D: score=1 STRING: ENSP00000269503
    CBLN4Q9NTU73, ENSP000000645714I2D: score=1 STRING: ENSP00000064571
    CBLN1P234353, ENSP000002191974I2D: score=1 STRING: ENSP00000219197
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CBLN3

    5 Novoseek inferred chemical compound relationships for CBLN3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    catecholamine 41 5 10022429 (2), 10688962 (1)
    corticosterone 40.9 1 10688962 (1)
    epinephrine 31.7 2 10688962 (1), 10022429 (1)
    norepinephrine 23.6 3 10688962 (2), 10022429 (1)
    steroid 19.6 3 12518246 (2), 10022429 (1)



    Find genes that share compounds with CBLN3           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for CBLN3 gene: 
    NM_001039771.2  

    Unigene Cluster for CBLN3:

    Cerebellin 3 precursor
    Hs.207603  [show with all ESTs]
    Unigene Representative Sequence: NM_001039771
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000267406(uc001wpg.4) ENST00000555436
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CBLN3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CBLN3 (see all 13):
    hsa-miR-596 hsa-miR-513a-5p hsa-miR-1271 hsa-miR-3155 hsa-miR-1205 hsa-miR-609 hsa-miR-484 hsa-miR-214*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CBLN3
    Predesigned siRNA for gene silencing in human, mouse, rat CBLN3
    Clone
    Products:
         
    OriGene clones in human, mouse for CBLN3 (see all 6)
    OriGene ORF clones in mouse, rat for CBLN3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CBLN3 (NM_001039771)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CBLN3
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CBLN3
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for CBLN3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CBLN3
      QuantiTect SYBR Green Assays in human, mouse, rat CBLN3
      QuantiFast Probe-based Assays in human, mouse, rat CBLN3

    Additional mRNA sequence: 

    AY359070.1 BC127674.1 BC127675.1 BC150549.1 BC150550.1 

    4 DOTS entries:

    DT.100770772  DT.110266  DT.100742133  DT.120753158 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    CBLN3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATTCATTCCT
    CBLN3 Expression
    About this image


    CBLN3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Brain (Nervous System)    fully expand to see all 9 entries
             Thalamus
             cerebellum   
    CBLN3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CBLN3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.207603
        Custom PCR Arrays for CBLN3
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for CBLN3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CBLN3
    QuantiTect SYBR Green Assays in human, mouse, rat CBLN3
    QuantiFast Probe-based Assays in human, mouse, rat CBLN3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBLN3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for CBLN3 gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cbln31 , 5 cerebellin 3 precursor protein1, 5 88.83(n)1
    97.16(a)1
      14 (28.19 cM)5
    564101  NM_019820.31  NP_062794.11 
     558789205 
    zebrafish
    (Danio rerio)
    Actinopterygii BX664707.16
    Uncharacterized protein
    55(a)
    many ↔ many
    7(1425421-1431202) ENSDARG00000063376


    ENSEMBL Gene Tree for CBLN3 (if available)
    TreeFam Gene Tree for CBLN3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for CBLN3 gene
    CBLN22  C1QL32  CBLN12  C1QTNF32  CAPRIN12  ENSG000002732942  C1QL22  CAPRIN22  
    C1QL12  CBLN42  C1QL42  
    5 SIMAP similar genes for CBLN3 using alignment to 2 protein entries:     CBLN3_HUMAN (see all proteins):
    CBLN1    CBLN2    CBLN4    CAPRIN2    COL8A2

    Find genes that share paralogs with CBLN3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for CBLN3 (see all 38)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs767087251,2
    C,F--24895350(+) TAAAAA/CATTCA 1 -- int13Minor allele frequency- C:0.02CSA WA NA 240
    rs1828208151,2
    --24895361(+) CCTTGC/TTCCAA 1 -- int10--------
    rs1508324181,2
    --24895570(+) GGTATA/TTTTTT 1 -- int10--------
    rs1380861891,2
    --24895632(+) CAGATG/TGTTCC 1 -- int10--------
    rs1442788811,2
    C--24895691(+) AAAAC-/CACAAAT 1 -- int10--------
    rs1881902221,2
    --24895814(+) CACCCA/GATCCA 1 -- ut310--------
    rs1495472631,2
    --24896043(+) ATCAGC/GAGAAA 1 -- ut310--------
    rs1459874831,2
    --24896066(+) GGATAC/TGCTGG 1 -- ut310--------
    rs1924315561,2
    C--24896279(+) AACACA/GCTCAC 1 -- ut310--------
    rs1822841361,2
    --24896317(+) CAGAGC/TCCATC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for CBLN3 (24895738 - 24900160 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for CBLN3: --
    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing CBLN3
    DNA2.0 Custom Variant and Variant Library Synthesis for CBLN3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 612978    OMIM disorders: --

    2 diseases for CBLN3:    
    About MalaCards
    spinocerebellar degeneration    olivopontocerebellar atrophy


    Find genes that share disorders with CBLN3           About GenesLikeMe


    Export disorders for CBLN3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for CBLN3 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with CBLN3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2, 3 Clark H.F.... Gray A.M. (Genome Res. 2003)
    2. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (Protein Sci. 2004)
    3. Biological, clinical and population relevance of 95 loci for blood lipids. (PubMed id 20686565)1 Teslovich T.M....Kathiresan S. (Nature 2010)
    4. Cbln1 is essential for interaction-dependent secretion of Cbln3. (PubMed id 17030622)1 Bao D....Morgan J.I. (Mol. Cell. Biol. 2006)
    5. Cbln3, a novel member of the precerebellin family that binds specifically to Cbln1. (PubMed id 10964938)1 Pang Z....Morgan J.I. (J. Neurosci. 2000)
    6. Cerebellin stimulates the secretory activity of the rat adrenal gland: in vitro and in vivo studies. (PubMed id 10688962)9 Albertin G....Nussdorfer G.G. (Neuropeptides 2000)
    7. Cerebellin enhances in vitro secretory activity of human adrenal gland. (PubMed id 10022429)9 Mazzocchi G....Nussdorfer G.G. (J. Clin. Endocrinol. Metab. 1999)
    8. Cerebellin and cerebellin mRNA in the human brain, adrenal glands and the tumour tissues of adrenal tumour, ganglioneuroblastoma and neuroblastoma. (PubMed id 9246935)9 Satoh F....Mouri T. (J. Endocrinol. 1997)
    9. [Cerebellin in the cerebellum in spinocerebellar degeneration]. (PubMed id 7495612)9 Mizuno Y....Itoyama Y. (No To Shinkei 1995)
    10. Decrease in cerebellin and corticotropin-releasing hormone in the cerebellum of olivopontocerebellar atrophy and Shy-Drager syndrome. (PubMed id 7583264)9 Mizuno Y....Itoyama Y. (Brain Res. 1995)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 643866 HGNC: 20146 Ensembl:ENSG00000139899 euGenes: HUgn643866 ECgene: CBLN3
    H-InvDB: CBLN3

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for CBLN3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for CBLN3 gene:
    Search GeneIP for patents involving CBLN3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for CBLN3   OriGene RNAi products in human, mouse, rat for CBLN3  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for CBLN3  
     OriGene MassSpec something-or-other for CBLN3   OriGene clones in human, mouse for CBLN3  
     OriGene qSTAR qPCR primer pairs in human, mouse for CBLN3   OriGene Purified Protein for CBLN3  
     OriGene ORF clones in mouse, rat for CBLN3   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CBLN3   OriGene Custom Protein Services for CBLN3  

     
     
     Block miRNA regulation of human, mouse, rat CBLN3 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CBLN3
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CBLN3 Predesigned siRNA for gene silencing in human, mouse, rat CBLN3
     QuantiFast Probe-based Assays in human, mouse, rat CBLN3 QuantiTect SYBR Green Assays in human, mouse, rat CBLN3
     Custom PCR Arrays for CBLN3 Search Chromatin IP Primers for CBLN3
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CBLN3  Search GeneGlobe Interaction Network for CBLN3
     Regulatory tfbs in CBLN3 promoter
     GenScript Custom Purified and Recombinant Proteins Services for CBLN3 GenScript cDNA clones with any tag delivered in your preferred vector for CBLN3
     GenScript Custom Assay Services for CBLN3 GenScript Custom overexpressing Cell Line Services for CBLN3
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for CBLN3
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for CBLN3
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Proteins for CBLN3
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     CBLN3 antibodies
     CBLN3 lysates
     Antibodies for CBLN3
     See all of Abcam's Antibodies, Kits and Proteins for CBLN3
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for CBLN3
     Antibodies for CBLN3
     ELISAs for CBLN3
     CLIAs for CBLN3



     Browse ESI BIO Cell Lines and PureStem Progenitors for CBLN3
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBLN3
     Browse SwitchGear 3'UTR luciferase reporter plasmids for CBLN3
     Browse SwitchGear Promoter luciferase reporter plasmids for CBLN3
     Search ThermoFisher Antibodies for CBLN3
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CBLN3
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CBLN3
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CBLN3
     LSBio Antibodies in human, mouse, rat for CBLN3
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for CBLN3
      Search eBioscience for proteins for CBLN3
      Search eBioscience for elisas for CBLN3
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      CBLN3 gene at Home site.
    Version: 3.12.224 13 Oct 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4