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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CBLN3 Gene

protein-coding   GIFtS: 43
GCID: GC14M024895

Cerebellin 3 Precursor

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Cerebellin 3 Precursor1 2
PRO14862
cerebellin-32

External Ids:    HGNC: 201461   Entrez Gene: 6438662   Ensembl: ENSG000001398997   OMIM: 6129785   UniProtKB: Q6UW013   

Export aliases for CBLN3 gene to outside databases

Previous GC identifers: GC00U907483 GC14U900191 GC14M023967 GC14M005010


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CBLN3 Gene:
Members of the precerebellin family, such as CBLN3, contain a cerebellin motif (see CBLN1; MIM 600432) and a
C-terminal C1q signature domain (see MIM 120550) that mediates trimeric assembly of atypical collagen complexes.
However, precerebellins do not contain a collagen motif, suggesting that they are not conventional components of
the extracellular matrix (Pang et al., 2000 (PubMed 10964938)).(supplied by OMIM, Aug 2009)

GeneCards Summary for CBLN3 Gene: 
CBLN3 (cerebellin 3 precursor) is a protein-coding gene. Diseases associated with CBLN3 include spinocerebellar degeneration, and olivopontocerebellar atrophy. An important paralog of this gene is CBLN2.

UniProtKB/Swiss-Prot: CBLN3_HUMAN, Q6UW01
Function: May be involved in synaptic functions in the CNS (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NC_018925.2  NT_026437.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CBLN3 gene promoter:
         AREB6   Tal-1   ITF-2   Tal-1beta   ATF6   E47   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for CBLN3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CBLN3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q12   Ensembl cytogenetic band:  14q12   HGNC cytogenetic band: 14q12

CBLN3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CBLN3 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M024895:  view genomic region     (about GC identifiers)

Start:
24,895,738 bp from pter      End:
24,900,160 bp from pter
Size:
4,423 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CBLN3_HUMAN, Q6UW01 (See protein sequence)
Recommended Name: Cerebellin-3 precursor  
Size: 205 amino acids; 21521 Da
Subunit: Heterohexamer; disulfide-linked heterotrimers. Interacts with CBLN1. May also form oligomers with CBLN2
AND CBLN4 (By similarity)
Subcellular location: Endoplasmic reticulum (By similarity). Golgi apparatus, cis-Golgi network (By similarity).
Secreted (By similarity). Cell junction, synapse (By similarity). Note=In the absence of CBLN1, remains in the
endoplasmic reticulum/cis-Golgi apparatus. Partial secretion depends on a association with CBLN1 and maybe CBLN4,
but not on CBLN2 (By similarity)

Explore the universe of human proteins at neXtProt for CBLN3: NX_Q6UW01

Explore proteomics data for CBLN3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6UW01

  • CBLN3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CBLN3 Protein Expression
    REFSEQ proteins: NP_001034860.1  
    ENSEMBL proteins: 
     ENSP00000267406   ENSP00000450935  

    Human Recombinant Protein Products for CBLN3: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    Enzo Life Sciences proteins for CBLN3
    OriGene Purified Protein for CBLN3
    OriGene Protein Over-expression Lysate for CBLN3
    OriGene MassSpec for CBLN3 
    OriGene Custom Protein Services for CBLN3
    GenScript Custom Purified and Recombinant Proteins Services for CBLN3
    Novus Biologicals CBLN3 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CBLN3 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IEA--
    GO:0005783endoplasmic reticulum IEA--
    GO:0005794Golgi apparatus IEA--
    GO:0030054cell junction IEA--
    GO:0045202synapse IEA--

    CBLN3 for ontologies           About GeneDecksing



    CBLN3 Antibody Products: 
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    Cloud-Clone Corp. Antibodies for CBLN3 
    Search ThermoFisher Antibodies for CBLN3
    LSBio Antibodies in human, mouse, rat for CBLN3 

    Assay Products for CBLN3: 
    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for CBLN3
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CBLN3 
    Cloud-Clone Corp. CLIAs for CBLN3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR008983 Tumour_necrosis_fac-like_dom
     IPR001073 C1q

    Graphical View of Domain Structure for InterPro Entry Q6UW01

    ProtoNet protein and cluster: Q6UW01

    1 Blocks protein domain: IPB001073 Complement C1q protein

    UniProtKB/Swiss-Prot: CBLN3_HUMAN, Q6UW01
    Similarity: Contains 1 C1q domain


    CBLN3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CBLN3_HUMAN, Q6UW01
    Function: May be involved in synaptic functions in the CNS (By similarity)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    CBLN3 for ontologies           About GeneDecksing


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Cbln3):
     behavior/neurological  nervous system  normal 

    CBLN3 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Cbln3tm1Jim for CBLN3

       inGenious Targeting Laboratory - Custom generated mouse model solutions for CBLN3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CBLN3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CBLN3 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CBLN3 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CBLN3
    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate CBLN3 (see all 13):
    hsa-miR-596 hsa-miR-513a-5p hsa-miR-1271 hsa-miR-3155 hsa-miR-1205 hsa-miR-609 hsa-miR-484 hsa-miR-214*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of CBLN3

    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for CBLN3 (see all 7)
    OriGene ORF clones in mouse, rat for CBLN3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CBLN3 (NM_001039771)
    Browse Sino Biological Human cDNA Clones
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    Sirion Biotech Customized lentivirus for stable overexpression of CBLN3 
                         Customized lentivirus expression plasmids for stable overexpression of CBLN3 

    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBLN3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CBLN3

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for CBLN3 (Q6UW013 ENSP000002674064) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CBLN2Q8IUK83, ENSP000002695034I2D: score=1 STRING: ENSP00000269503
    CBLN4Q9NTU73, ENSP000000645714I2D: score=1 STRING: ENSP00000064571
    CBLN1P234353, ENSP000002191974I2D: score=1 STRING: ENSP00000219197
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CBLN3 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CBLN3

    5 Novoseek inferred chemical compound relationships for CBLN3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    catecholamine 41 5 10022429 (2), 10688962 (1)
    corticosterone 40.9 1 10688962 (1)
    epinephrine 31.7 2 10688962 (1), 10022429 (1)
    norepinephrine 23.6 3 10688962 (2), 10022429 (1)
    steroid 19.6 3 12518246 (2), 10022429 (1)

    Search CenterWatch for drugs/clinical trials and news about CBLN3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CBLN3 gene: 
    NM_001039771.2  

    Unigene Cluster for CBLN3:

    Cerebellin 3 precursor
    Hs.207603  [show with all ESTs]
    Unigene Representative Sequence: NM_001039771
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000267406(uc001wpg.4) ENST00000555436
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CBLN3
    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate CBLN3 (see all 13):
    hsa-miR-596 hsa-miR-513a-5p hsa-miR-1271 hsa-miR-3155 hsa-miR-1205 hsa-miR-609 hsa-miR-484 hsa-miR-214*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CBLN3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CBLN3
    Clone
    Products:
         
    OriGene clones in human, mouse for CBLN3 (see all 7)
    OriGene ORF clones in mouse, rat for CBLN3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CBLN3 (NM_001039771)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CBLN3
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CBLN3
    Sirion Biotech Customized lentivirus for stable overexpression of CBLN3 
                         Customized lentivirus expression plasmids for stable overexpression of CBLN3 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for CBLN3
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CBLN3
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CBLN3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CBLN3

    Additional mRNA sequence: 

    AY359070.1 BC127674.1 BC127675.1 BC150549.1 BC150550.1 

    4 DOTS entries:

    DT.100770772  DT.110266  DT.100742133  DT.120753158 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CBLN3 expression in normal human tissues (normalized intensities)      CBLN3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATTCATTCCT
    CBLN3 Expression
    About this image


    CBLN3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Brain (Nervous System)    fully expand to see all 9 entries
             Thalamus
             cerebellum   
     
     Spinal Cord (Nervous System)
             Dorsal Horn   

    See CBLN3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CBLN3

    SOURCE GeneReport for Unigene cluster: Hs.207603
        SABiosciences Custom PCR Arrays for CBLN3
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for CBLN3
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CBLN3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBLN3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for CBLN3 gene from 2/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cbln31 , 5 cerebellin 3 precursor protein1, 5 88.02(n)1
    94.27(a)1
      14 (28.19 cM)5
    564101  NM_019820.31  NP_062794.11 
     558789205 
    fruit fly
    (Drosophila melanogaster)
    Insecta Capr6
    Caprin
    2(a)
    1 → many
    3L(18661253-18666260)


    ENSEMBL Gene Tree for CBLN3 (if available)
    TreeFam Gene Tree for CBLN3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CBLN3 gene
    CBLN22  C1QL32  CBLN12  C1QTNF32  CAPRIN12  C1QL22  CAPRIN22  C1QL12  
    CBLN42  C1QL42  
    5 SIMAP similar genes for CBLN3 using alignment to 2 protein entries:     CBLN3_HUMAN (see all proteins):
    CBLN1    CBLN2    CBLN4    CAPRIN2    COL8A2

    CBLN3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/38 SNPs in CBLN3 are shown (see all 38)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs767087251,2
    C,F--24895350(+) TAAAAA/CATTCA 1 -- int13Minor allele frequency- C:0.02CSA WA NA 240
    rs1828208151,2
    --24895361(+) CCTTGC/TTCCAA 1 -- int10--------
    rs1508324181,2
    --24895570(+) GGTATA/TTTTTT 1 -- int10--------
    rs1380861891,2
    --24895632(+) CAGATG/TGTTCC 1 -- int10--------
    rs1442788811,2
    C--24895691(+) AAAAC-/CACAAAT 1 -- int10--------
    rs1881902221,2
    --24895814(+) CACCCA/GATCCA 1 -- ut310--------
    rs1495472631,2
    --24896043(+) ATCAGC/GAGAAA 1 -- ut310--------
    rs1459874831,2
    --24896066(+) GGATAC/TGCTGG 1 -- ut310--------
    rs1924315561,2
    C--24896279(+) AACACA/GCTCAC 1 -- ut310--------
    rs1822841361,2
    --24896317(+) CAGAGC/TCCATC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for CBLN3 (24895738 - 24900160 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for CBLN3: --
    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing CBLN3
    DNA2.0 Custom Variant and Variant Library Synthesis for CBLN3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612978    OMIM disorders: --

    4 diseases for CBLN3:    About MalaCards
    spinocerebellar degeneration    olivopontocerebellar atrophy    ganglioneuroblastoma    neuroblastoma


    CBLN3 for disorders           About GeneDecksing


    Export disorders for CBLN3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CBLN3 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with CBLN3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2, 3 Clark H.F.... Gray A.M. (2003)
    2. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (2004)
    3. Biological, clinical and population relevance of 95 l oci for blood lipids. (PubMed id 20686565)1 Teslovich T.M....Kathiresan S. (2010)
    4. Cbln1 is essential for interaction-dependent secretion of Cbln3. (PubMed id 17030622)1 Bao D....Morgan J.I. (2006)
    5. Cbln3, a novel member of the precerebellin family that binds specifically to Cbln1. (PubMed id 10964938)1 Pang Z....Morgan J.I. (2000)
    6. Cerebellin stimulates the secretory activity of the rat adrenal gland: in vitro and in vivo studies. (PubMed id 10688962)9 Albertin G....Nussdorfer G.G. (2000)
    7. Cerebellin enhances in vitro secretory activity of human adrenal gland. (PubMed id 10022429)9 Mazzocchi G....Nussdorfer G.G. (1999)
    8. Cerebellin and cerebellin mRNA in the human brain, adrenal glands and the tumour tissues of adrenal tumour, ganglioneuroblastoma and neuroblastoma. (PubMed id 9246935)9 Satoh F....Mouri T. (1997)
    9. [Cerebellin in the cerebellum in spinocerebellar degeneration] (PubMed id 7495612)9 Mizuno Y....Itoyama Y. (1995)
    10. Decrease in cerebellin and corticotropin-releasing hormone in the cerebellum of olivopontocerebellar atrophy and Shy-Drager syndrome. (PubMed id 7583264)9 Mizuno Y....Itoyama Y. (1995)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 643866 HGNC: 20146 Ensembl:ENSG00000139899 euGenes: HUgn643866 ECgene: CBLN3
    H-InvDB: CBLN3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CBLN3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CBLN3 gene:
    Search GeneIP for patents involving CBLN3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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    (GIFtS: 73)
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    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

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