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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CBLN2 Gene

protein-coding   GIFtS: 47
GCID: GC18M070203

cerebellin 2 precursor
 Explore 1 disease affiliated with
CBLN2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for CBLN2    

Aliases
for CBLN2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Cerebellin 2 Precursor1 2
Cerebellin-21

External Ids:    HGNC: 15441   Entrez Gene: 1473812   Ensembl: ENSG000001416687   OMIM: 6004335   UniProtKB: Q8IUK83   

Export aliases for CBLN2 gene to outside databases

Previous GC identifers: GC18U990007 GC18M068352 GC18M068354 GC18M066922


Summaries
for CBLN2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
  --

Genomic Views
for CBLN2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000018.9  NC_018929.1  NT_025028.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CBLN2 gene promoter:
         TBP   NF-1   USF1   FOXF2   Nkx2-5   FOXL1   Gfi-1   MEF-2A   USF-1   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CBLN2 promoter sequence
   Search SABiosciences Chromatin IP Primers for CBLN2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CBLN2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q22.3   Ensembl cytogenetic band:  18q22.3   HGNC cytogenetic band: 18q22.3

CBLN2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CBLN2 gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18M070203:  view genomic region     (about GC identifiers)

Start:
 70,203,915 bp from pter      End:
 70,305,756 bp from pter
Size:
 101,842 bases      Orientation:
 minus strand

Proteins
for CBLN2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CBLN2_HUMAN, Q8IUK8 (See protein sequence)
Recommended Name: Cerebellin-2  
Size: 224 amino acids; 24084 Da
Subunit: May interact with CBLN1, CBLN3 and CBLN4 (By similarity)
Subcellular location: Membrane; Single-pass membrane protein (Potential)
Secondary accessions: Q53Z56

Explore the universe of human proteins at neXtProt for CBLN2: NX_Q8IUK8

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8IUK8

    • CBLN2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_872317.1  
    ENSEMBL proteins: 
     ENSP00000463771   ENSP00000269503   ENSP00000464490   ENSP00000462632  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    R&D Systems Recombinant & Natural Proteins for CBLN2 (Cerebellin-2)
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    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: CBLN2
    OriGene Custom Protein Services for CBLN2 
    GenScript Custom Purified and Recombinant Proteins Services for CBLN2
    Novus Biologicals CBLN2 Protein
    Novus Biologicals CBLN2 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for CBLN2

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IEA--
    GO:0016021integral to membrane IEA--


    CBLN2 for ontologies           About GeneDecksing



    CBLN2 Antibody Products: 
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    Novus Biologicals CBLN2 Antibody
    Search for Antibodies for CBLN2 at Abcam  
    Uscn Antibodies for CBLN2
    Search ThermoFisher Antibodies for CBLN2

    Assay Products for CBLN2: 
    Browse Kits and Assays available from EMD Millipore
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    Browse OriGene Fluorogenic Cell Assay Kits
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    GenScript Custom Assay Services for CBLN2
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for CBLN2

    Protein Domains /
    Families
    for CBLN2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CBLN2 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR008983 Tumour_necrosis_fac-like_dom
     IPR001073 C1q

    Graphical View of Domain Structure for InterPro Entry Q8IUK8

    ProtoNet protein and cluster: Q8IUK8

    1 Blocks protein family: IPB001073 Complement C1q protein

    UniProtKB/Swiss-Prot: CBLN2_HUMAN, Q8IUK8
    Similarity: Contains 1 C1q domain


    Function
    for CBLN2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    miRNA
    Products:            		 OriGene 3'-UTR Clone: CBLN2
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CBLN2
    8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate CBLN2 (see all 11):
    hsa-miR-517a hsa-miR-526b hsa-miR-513a-5p hsa-miR-517c hsa-miR-548e hsa-miR-517b hsa-miR-1284 hsa-miR-548a-3p
    SwitchGear 3'UTR luciferase reporter plasmid: CBLN2 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CBLN2 (see all 6)
    Browse OriGene siRNA
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CBLN2

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for CBLN2

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CBLN2 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CBLN2
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: CBLN2 (NM_182511)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CBLN2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CBLN2 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for CBLN2
    Search LifeMap BioReagents cell lines for CBLN2

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBLN2

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----


    CBLN2 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Cbln2tm1Jim for CBLN2
         2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Cbln2):
     behavior/neurological  nervous system 

    CBLN2 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for CBLN2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CBLN2

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for CBLN2 (Q8IUK83 ENSP000002695034) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CBLN3Q6UW013, ENSP000002674064I2D: score=1 STRING: ENSP00000267406
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0051965positive regulation of synapse assembly IEA--


    CBLN2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for CBLN2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CBLN2
    Search CenterWatch for drugs/clinical trials and news about CBLN2 

    Transcripts
    for CBLN2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CBLN2 gene: 
    NM_182511.3  

    Unigene Cluster for CBLN2:

    Cerebellin 2 precursor
    Hs.569851  [show with all ESTs]
    Unigene Representative Sequence: AK125422
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000585159(uc002lku.2) ENST00000269503(uc002lkv.2) ENST00000581425
    ENST00000584764 ENST00000583651 ENST00000581073 ENST00000580889 ENST00000583570
    ENST00000582667

    miRNA
    Products:             		 OriGene 3'-UTR Clone: CBLN2
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CBLN2
    8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate CBLN2 (see all 11):
    hsa-miR-517a hsa-miR-526b hsa-miR-513a-5p hsa-miR-517c hsa-miR-548e hsa-miR-517b hsa-miR-1284 hsa-miR-548a-3p
    SwitchGear 3'UTR luciferase reporter plasmid: CBLN2 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CBLN2 (see all 6)
    Browse OriGene siRNA
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CBLN2
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CBLN2 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CBLN2
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: CBLN2 (NM_182511)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CBLN2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CBLN2 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CBLN2
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CBLN2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CBLN2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CBLN2

    Additional cDNA sequence: 

    AK125422.1 AK291364.1 AY359074.1 BC035789.1 BC110843.1 

    3 DOTS entries:

    DT.75130678  DT.97783826  DT.100684052 

    24/29 AceView cDNA sequences (see all 29):

    CB118124 AY359074 AW162063 NM_182511 BU734103 BX460500 T17432 BU102038 
    BC035789 BX409761 AK125422 BX409762 BM987080 AA340432 AA332557 BI917364 
    BM723762 BI871154 CA396230 BE644911 R36770 AW163243 AI815729 AW965432 

    GeneLoc Exon Structure


    Expression
    for CBLN2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CBLN2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CACCTGGCGA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    CBLN2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BrainBlood Brain BarrierPostnatal Endothelial CellsBlood Brain Barrier, Endothelium
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 4 LifeMap Cells 
    NameCategory
    PureStem™ endothelial progenitor 30-MV2-12 (Embryonic Progenitor Cell)Blood, Endothelium
    PureStem™ endothelial progenitor 30-SM2-1 (Embryonic Progenitor Cell)Endothelium
    PureStem™ endothelial progenitor 30-MV2-14 (Embryonic Progenitor Cell)Endothelium
    Pancreatic endoderm/endocrine precursor-like cells (A scalable, suspensi...)

    See CBLN2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CBLN2

    SOURCE GeneReport for Unigene cluster: Hs.569851
        SABiosciences Custom PCR Arrays for CBLN2
    Primer
    Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CBLN2
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    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CBLN2
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CBLN2
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBLN2

    Orthologs
    for CBLN2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for CBLN2 gene from 4/13 species (see all 13)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves CBLN21 cerebellin 2 88.89(n)
    95.65(a)    		   421019  NM_001171768.1  NP_001165239.1 
    lizard
    (Anolis carolinensis)    		 Reptilia CBLN26
    		 --
    		 84(a)
    		 1 ↔ 1
    		 4(48247810-48254792)
    African clawed frog
    (Xenopus laevis)    		 Amphibia cbln2-prov2 cerebellin 2 precursor protein 80.96(n)    BC054217.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii cbln2b1 cerebellin 2b precursor 71.38(n)
    82.83(a)    		   560583  NM_001098738.1  NP_001092208.1 


    ENSEMBL Gene Tree for CBLN2 (if available)
    TreeFam Gene Tree for CBLN2 (if available) 

    Paralogs
    for CBLN2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CBLN2 gene
    CBLN12  CBLN42  CAPRIN12  CBLN32  CAPRIN22  
    5 SIMAP similar genes for CBLN2 using alignment to 3 protein entries:     CBLN2_HUMAN (see all proteins):
    CBLN4    CBLN1    CBLN3    CAPRIN2    COL8A2

    CBLN2 for paralogs           About GeneDecksing



    Genomic Variants
    for CBLN2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/172 NCBI SNPs in CBLN2 are shown (see all 172)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 18 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs759810511,2
    		C--70203419(+) CAGTAA/TAACTT 1 -- int10--------
    rs773012531,2
    		C--70203421(+) GTAAAA/CCTTAG 1 -- int10--------
    rs761930871,2
    		--70203485(+) TCTTCA/GAAAAT 1 -- int10--------
    rs1180227421,2
    		F,--70203543(+) TTATGC/TGCTTA 1 -- int11Minor allele frequency- T:0.02NA 120
    rs1909967441,2
    		--70203544(+) TATGCA/GCTTAA 1 -- int10--------
    rs1439616541,2
    		--70203648(+) CCTAGA/CCCTAA 1 -- int10--------
    rs1505369121,2
    		--70203776(+) GTCTGC/TACATA 1 -- int10--------
    rs6166821,2
    		C,F,A,H,--70203793(+) TGTGTG/ATGTTT 1 -- int123Minor allele frequency- A:0.20NS EA NA WA CSA 1781
    rs2020426301,2
    		--70203796(+) GTATG-/TTTGAGA 1 -- int10--------
    rs1403910811,2
    		--70203797(+) TATGT-/TTGA  
                GAGTA     		1 -- int10--------

    HapMap Linkage Disequilibrium report for CBLN2 (70203915 - 70305756 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for CBLN2: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CBLN2
    DNA2.0 Custom Variant and Variant Library Synthesis for CBLN2

    Disorders / Diseases
    for CBLN2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CBLN2 for disorders           About GeneDecksing

    OMIM gene information: 600433    OMIM disorders: --

    1 disease for CBLN2:    About MalaCards
    multiple sclerosis


    Export disorders for CBLN2 gene to outside databases

    Publications
    for CBLN2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CBLN2 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with CBLN2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    4. Genomic structure and mapping of precerebellin and a precerebellin-related gene. (PubMed id 7877445)1, 3 Kavety B....Morgan J.I. (1994)
    5. Investigation of single nucleotide polymorphisms and b iological pathways associated with response to TNFa inhibitors in patients with rheumatoid arthritis. (PubMed id 22569225)1 Krintel S.B....Hetland M.L. (2012)
    6. Comparison of Cbln1 and Cbln2 functions using transgen ic and knockout mice. (PubMed id 22117778)1 Rong Y....Morgan J.I. (2012)
    7. Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. (PubMed id 19010793)1 Baranzini S.E....Oksenberg J.R. (2008)
    8. Cbln1 is essential for interaction-dependent secretion of Cbln3. (PubMed id 17030622)1 Bao D....Morgan J.I. (2006)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Precerebellin-related genes and precerebellin 1 peptide in the adrenal gland of the rat: expression pattern, localization, developmental regulation and effects on corticosteroidogenesis. (PubMed id 19212655)9 Rucinski M....Malendowicz L.K. (2009)

    External Searches for CBLN2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing CBLN2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 147381 HGNC: 1544 AceView: CBLN2 Ensembl:ENSG00000141668 euGenes: HUgn147381
    ECgene: CBLN2 H-InvDB: CBLN2

    Other Databases showing CBLN2 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing CBLN2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CBLN2 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for CBLN2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for CBLN2 gene:
    Search GeneIP for patents involving CBLN2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
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     EMD Millipore Custom Antibody & Bulk Services
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     Regulatory tfbs in CBLN2 promoter
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     CBLN2 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for CBLN2
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     SwitchGear 3'UTR luciferase reporter plasmids for CBLN2
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     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CBLN2
           
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