CBLL1 Gene
protein-coding GIFtS: 54
GCID: GC07P107385
|
|
Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1(Previous name: Cas-Br-M (murine) ecotropic retroviral transforming sequence-like...)
| |
Aliases for CBLL1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
| This gene clusters with an RNA gene Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Cbl Proto-Oncogene, E3 Ubiquitin Protein Ligase-Like 11 2 | | RING Finger Protein 1882 3 | | HAKAI1 2 3 5 | | FLJ231091 | | RNF1881 2 3 5 | | E-Cadherin Binding Protein E72 | | Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 11 2 | | E3 Ubiquitin-Protein Ligase Hakai2 | | Casitas B-Lineage Lymphoma-Transforming Sequence-Like Protein 12 3 | | EC 6.3.2.-3 | | C-Cbl-Like Protein 12 3 | | EC 6.3.28 |
| External Ids: | HGNC: 212251 | Entrez Gene: 798722 | Ensembl: ENSG000001058797 | OMIM: 6068725 | UniProtKB: Q75N033 |
|---|
| | ORGUL members: | |
|---|
| NONCODE:n406663 | |
Export aliases for CBLL1 gene to outside databasesPrevious GC identifers: GC07P106931 GC07P106945 GC07P106978 GC07P107171 GC07P101746
Summaries for CBLL1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for CBLL1: This gene encodes an E3 ubiquitin-ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, anddegradation in the lysosomes. The encoded protein contains a RING-finger domain and is also thought to have a role incontrol of cell proliferation. A related pseudogene has been identified on chromosome X. Alternative splicing resultsin a non-coding transcript variant. (provided by RefSeq, Aug 2011) UniProtKB/Swiss-Prot: HAKAI_HUMAN, Q75N03Function: Promotes ubiquitination of several tyrosine-phosphorylated Src substrates, including CDH1, CTTN and DOK1.Targets CDH1 for endocytosis and degradation (By similarity)
|
Genomic Views for CBLL1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079596.2
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the CBLL1 gene promoter: c-Fos Spz1 AP-1 AML1a JunB Fra-1 FosB CUTL1 JunD c-Jun Other transcription factors
Search SABiosciences Chromatin IP Primers for CBLL1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CBLL1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q22.3 Ensembl cytogenetic band: 7q22.3 HGNC cytogenetic band: 7q22.3CBLL1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P107385: view genomic region
(about GC identifiers)
Start:
|
107,384,142 bp from pter |
End:
|
107,402,083 bp from pter |
Size:
|
17,942 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 106,745,399-106,763,197 |
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Proteins for CBLL1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: HAKAI_HUMAN, Q75N03 (See
protein sequence)Recommended Name: E3 ubiquitin-protein ligase Hakai Size: 491 amino acids; 54519 Da
Subunit: Homodimer. Interacts with tyrosine-phosphorylated SRC substrates
Secondary accessions: Q8TAJ4 Q9H5S6Explore the universe of human proteins at neXtProt for CBLL1: NX_Q75N03
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q75N03 4/14 DME Specific Peptides for CBLL1 (Q75N03) (see all 14)
CBLL1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_079090.2 ENSEMBL proteins: ENSP00000401277 ENSP00000401374 ENSP00000222597 ENSP00000410615 ENSP00000401175 ENSP00000412126 Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
CBLL1 for ontologies About GeneDecksing
CBLL1 Antibody Products: Assay Products for CBLL1: |
Protein
Domains / Families for CBLL1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CBLL1 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q75N03ProtoNet protein and cluster: Q75N03 1 Blocks protein family: IPB001841 Zn-finger
UniProtKB/Swiss-Prot: HAKAI_HUMAN, Q75N03Domain: The HYB domain forms a phosphotyrosine-binding pocket upon dimerization, and mediates as well the recognitionof its flanking acidic amino acids (By similarity)Similarity: Contains 1 C2H2-type zinc fingerSimilarity: Contains 1 RING-type zinc finger |
Function for CBLL1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: HAKAI_HUMAN, Q75N03Function: Promotes ubiquitination of several tyrosine-phosphorylated Src substrates, including CDH1, CTTN and DOK1.Targets CDH1 for endocytosis and degradation (By similarity)Enzyme Numbers (IUBMB): EC 6.3.2.-1 EC 6.3.22
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CBLL1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CBLL1 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CBLL1 (NM_024814) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CBLL1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CBLL1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBLL1 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
CBLL1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for CBLL1:
|
Pathways & Interactions for CBLL1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Remodeling of Adherens Junctions | |
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for CBLL1
UniProtKB/Swiss-Prot: HAKAI_HUMAN, Q75N03Pathway: Protein modification; protein ubiquitinationInteractions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CBLL1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 8)
 5/10 Interacting proteins for CBLL1 (Q75N032, 3 ENSP000004012774) via UniProtKB, MINT, STRING, and/or I2D (see all 10) About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
CBLL1 for ontologies About GeneDecksing
|
Drugs & Compounds for CBLL1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for CBLL1 Search CenterWatch for drugs/clinical trials and news about CBLL1 / HAKAI 
|
Transcripts for CBLL1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for CBLL1 gene: NM_024814.2 Unigene Cluster for CBLL1: Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1 Hs.592271 [show with all ESTs]Unigene Representative Sequence: NR_02419910 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000440859(uc011kme.2 uc003veq.3 uc011kmf.2) ENST00000479443 ENST00000432748 ENST00000222597 ENST00000493361 ENST00000487517 ENST00000420796 ENST00000477356 ENST00000415884 ENST00000417616
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CBLL1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CBLL1 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CBLL1 (NM_024814) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CBLL1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CBLL1  |
Additional cDNA sequence: AK026762.1 AK293352.1 AK307992.1 BC027460.2 BC130529.1 BC130531.1 BC144176.1 NR_024199.1 5 DOTS entries: DT.40250069 DT.100647692 DT.95322156 DT.95360962 DT.92026774 24/75 AceView cDNA sequences (see all 75): AW299300 BF439526 BC027460 BG496198 AI823954 BX089724 BG288837 BU173348 AA831893 BQ224139 AW151683 BM683498 BP350093 AW450317 BG687056 BF056210 CR623864 CR608275 N89881 AI055864 NM_024814 BX437524 CD651877 AW043930 GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for CBLL1 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | |
| SP1: | |   | |   | - |   | |   | - |   | - |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for CBLL1
|
Expression for CBLL1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CBLL1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: GTGGTCCACC
About this image See CBLL1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for CBLL1
SOURCE GeneReport for Unigene cluster: Hs.592271 SABiosciences Expression via Pathway-Focused PCR Arrays including CBLL1:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CBLL1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CBLL1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CBLL1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CBLL1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBLL1 |
Orthologs for CBLL1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CBLL1 gene from 7/17 species (see all 17) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
CBLL11 |
Cbl proto-oncogene, E3 ubiquitin protein ligase-like more |
82.15(n) 90.63(a) |
  |
417701 NM_001007848.1 NP_001007849.1 |
lizard (Anolis carolinensis) |
Reptilia |
-- |
-- |
89(a) |
1 → many |
5(97639568-97645224) |
African clawed frog (Xenopus laevis) |
Amphibia |
Xl.34842 |
Xenopus laevis transcribed sequence with moderate similarity more |
80.63(n) |
  |
BU915495.1 |
zebrafish (Danio rerio) |
Actinopterygii |
zgc553082 |
similar to Casitas B-lineage lymphoma-like 1 |
75.49(n) |
  |
394041 BC048028.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
Hakai6 |
Hakai |
21(a) |
1 → many |
2L(19580612-19582474) |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
AT5G011606 |
e-cadherin binding protein-like protein |
16(a) |
1 → many |
5(54010-55856) |
rice (Oryza sativa) |
Liliopsida |
-- |
ZOS10-06 - C2H2 zinc finger protein, expressed |
14(a) |
1 → many |
10(18723094-18727119) |
ENSEMBL Gene Tree for CBLL1 (if available) TreeFam Gene Tree for CBLL1 (if available)  |
Paralogs for CBLL1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for CBLL1 gene
- ZNF6452
1 SIMAP similar gene for CBLL1 using alignment to 7 protein entries: HAKAI_HUMAN (see all proteins):ZNF645
CBLL1 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for CBLL1 PGOHUM00000241523 PGOHUM00000241662
|
Genomic Variants for CBLL1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 7 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for CBLL1 (107384142 - 107402083 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for CBLL1: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CBLL1 |
|
Disorders
/ Diseases for CBLL1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CBLL1 for disorders About GeneDecksing
OMIM gene information: 606872
OMIM disorders: --
7 diseases for CBLL1: About MalaCardstick-borne encephalitis yellow fever encephalitis colon cancer breast carcinoma breast cancer carcinoma 2 diseases from the University of Copenhagen DISEASES database for CBLL1:tick-borne encephalitis Yellow fever Human Genome Epidemiology (HuGE) Navigator: CBLL1 (1 document) Export disorders for CBLL1 gene to outside databases
|
Publications for CBLL1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CBLL1 gene, integrated from 9 sources (see all 26): (articles sorted by number of sources associating them with CBLL1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
- Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex. (PubMed id 11836526)1, 3 Fujita Y....Birchmeier W. (2002)
- E-cadherin and Hakai: signalling, remodeling or destruction? (PubMed id 11944035)1, 3 Pece S. and Gutkind J.S. (2002)
- Rack1 promotes epithelial cell-cell adhesion by regul ating E-cadherin endocytosis. (PubMed id 21685945)1 Swaminathan G. and Cartwright C.A. (2012)
- Reduced surface expression of epithelial E-cadherin ev oked by interferon-gamma is Fyn kinase-dependent. (PubMed id 22715382)1 Smyth D....McKay D.M. (2012)
- Structure of a novel phosphotyrosine-binding domain in Hakai that targets E-cadherin. (PubMed id 22252131)1 Mukherjee M....Sivaraman J. (2012)
- Slit-Robo signaling induces malignant transformation through Hakai-mediated E-cadherin degradation during colorectal epithelial cell carcinogenesis. (PubMed id 21283129)1 Zhou W.J....Geng J.G. (2011)
- Appraising the roles of CBLL1 and the ubiquitin/prote asome system for flavivirus entry and replication. (PubMed id 21191016)1 Fernandez-Garcia M.D....Amara A. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Hakai acts as a coregulator of estrogen receptor alph a in breast cancer cells. (PubMed id 20608937)1 Gong E.Y....Lee K. (2010)
|
External Searches for CBLL1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing CBLL1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CBLL1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CBLL1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
|
About This Section
| Patent Information for CBLL1 gene: Search GeneIP for patents involving CBLL1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for CBLL1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for CBLL1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CBLL1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CBLL1 | | OriGene Protein Over-expression Lysate for CBLL1 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for CBLL1 | | OriGene 3'-UTR Clone for CBLL1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CBLL1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CBLL1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for CBLL1 | | OriGene Custom Protein Services for CBLL1 | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CBLL1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CBLL1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CBLL1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CBLL1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CBLL1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CBLL1 |
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 |  |  |  | |
| | | Search Tocris compounds for CBLL1 |
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 | | CBLL1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CBLL1 |
|  |  |  | | | Search ThermoFisher Antibodies for CBLL1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CBLL1 |
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