Aliases for CATSPERZ Gene
Aliases for CATSPERZ Gene
External Ids for CATSPERZ Gene
- HGNC: 19231
- Entrez Gene: 25858
- Ensembl: ENSG00000219435
- UniProtKB: Q9NTU4
Previous HGNC Symbols for CATSPERZ Gene
- C11orf20
- TEX40
Summaries for CATSPERZ Gene
GeneCards Summary for CATSPERZ Gene
CATSPERZ (Catsper Channel Auxiliary Subunit Zeta) is a Protein Coding gene.
UniProtKB/Swiss-Prot for CATSPERZ Gene
-
May be involved in late spermatogenesis.
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CATSPERZ Gene
Genomics for CATSPERZ Gene
Regulatory Elements for CATSPERZ Gene
Enhancers for CATSPERZ Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH11G064320 | 1.4 | Ensembl ENCODE dbSUPER | 12.2 | +22.7 | 22729 | 5.3 | HDAC1 KLF17 NFXL1 RAD21 ZNF366 EGR1 SCRT2 EGR2 ZNF263 ZBTB2 | PLCB3 LOC102723878 ENSG00000257086 CATSPERZ ENSG00000207024 KCNK4 KCNK4-TEX40 BAD GPR137 TRMT112 |
| GH11G064205 | 1.4 | ENCODE dbSUPER | 11.5 | -92.8 | -92796 | 4.4 | HDGF PKNOX1 CREB3L1 ARNT AGO1 ARID4B SIN3A DMAP1 ZNF2 YY1 | ZFPL1 TRPT1 ENSG00000257086 PLCB3 TRMT112 GPR137 BAD KCNK4-TEX40 KCNK4 ENSG00000207024 |
| GH11G064347 | 0.8 | ENCODE | 11.5 | +48.0 | 47991 | 1.9 | BCOR KLF1 JUN CHD4 ZMYM3 MAX CEBPG ZNF366 POLR2A FOXK2 | LOC102723878 MIR1237 PRDX5 TRMT112 ESRRA CATSPERZ ENSG00000207024 KCNK4-TEX40 KCNK4 BAD |
| GH11G064299 | 0.5 | ENCODE | 0.7 | -1.0 | -1008 | 0.2 | SUZ12 FUS HNRNPL EZH2 | ENSG00000207024 CATSPERZ |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CATSPERZ on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for CATSPERZ Gene
- Chromosome:
- 11
- Start:
- 64,300,391 bp from pter
- End:
- 64,304,770 bp from pter
- Size:
- 4,380 bases
- Orientation:
- Plus strand
Genomic View for CATSPERZ Gene
Genes around CATSPERZ on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q13.1 by Ensembl
- 11q13.1 by Entrez Gene
- 11q13.1 by HGNC
CATSPERZ Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CATSPERZ Gene
Proteins for CATSPERZ Gene
-
Protein details for CATSPERZ Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9NTU4-TEX40_HUMAN
- Recommended name:
- Testis-expressed protein 40
- Protein Accession:
- Q9NTU4
Protein attributes for CATSPERZ Gene
- Size:
- 200 amino acids
- Molecular mass:
- 22839 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for CATSPERZ Gene
Other Protein References for CATSPERZ Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for CATSPERZ
- Invitrogen Antibodies for CATSPERZ
- antibodies-online Antibodies for CATSPERZ: See all 8
- Search GeneTex for Antibodies for CATSPERZ
Protein Products
-
OriGene Purified Proteins for CATSPERZ
- Search Origene for MassSpec and Protein Over-expression Lysates for CATSPERZ
- Origene Custom Protein Services for CATSPERZ
- Search GeneTex for Proteins for CATSPERZ
Assay Products
No data available for DME Specific Peptides for CATSPERZ Gene
Domains & Families for CATSPERZ Gene
Protein Domains for CATSPERZ Gene
- ProtoNet:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CATSPERZ Gene
Function for CATSPERZ Gene
Molecular function for CATSPERZ Gene
- UniProtKB/Swiss-Prot Function:
- May be involved in late spermatogenesis.
Phenotypes for CATSPERZ Gene
- MGI mutant phenotypes for CATSPERZ:
- inferred from 1 alleles
Animal Models for CATSPERZ Gene
- MGI Knock Outs for CATSPERZ:
-
- Catsperz tm1.1(KOMP)Vlcg
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CATSPERZ
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CATSPERZ gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CATSPERZ gene
- Search ViGene Biosciences for CATSPERZ
CRISPR Products
-
OriGene CRISPR knockouts for CATSPERZ
miRNA Products
- Search ViGene Biosciences for CATSPERZ
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for CATSPERZ
- Browse OriGene Inhibitory RNA Products For CATSPERZ
-
ViGene Biosciences ready-to-package AAV shRNAs for CATSPERZ gene
Clone Products
-
OriGene ORF clones in human for CATSPERZ
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- VectorBuilder custom plasmid, inducible vectors for CATSPERZ
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CATSPERZ
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CATSPERZ
-
ViGene Biosciences adenoviral particle packaged cDNA for CATSPERZ gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CATSPERZ gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CATSPERZ gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for CATSPERZ Gene
Localization for CATSPERZ Gene
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| cytosol | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IDA | -- |
| GO:0036128 | CatSper complex | ISS | -- |
| GO:0097228 | sperm principal piece | IDA | 28226241 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for CATSPERZ Gene
Pathways & Interactions for CATSPERZ Gene
No Data Available
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007140 | male meiosis | IEA,ISS | -- |
| GO:0007283 | spermatogenesis | ISS,IEA | -- |
| GO:0030154 | cell differentiation | IEA | -- |
| GO:0030317 | flagellated sperm motility | ISS | -- |
| GO:0048240 | sperm capacitation | ISS | -- |
No data available for Pathways by source and SIGNOR curated interactions for CATSPERZ Gene
Transcripts for CATSPERZ Gene
mRNA/cDNA for CATSPERZ Gene
- (1) REFSEQ mRNAs :
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for CATSPERZ
miRNA Products
- Search ViGene Biosciences for CATSPERZ
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for CATSPERZ
- Browse OriGene Inhibitory RNA Products For CATSPERZ
-
ViGene Biosciences ready-to-package AAV shRNAs for CATSPERZ gene
Clone Products
-
OriGene ORF clones in human for CATSPERZ
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- VectorBuilder custom plasmid, inducible vectors for CATSPERZ
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CATSPERZ
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for CATSPERZ Gene
NURSA nuclear receptor signaling pathways regulating expression of CATSPERZ Gene:
CATSPERZEvidence on tissue expression from TISSUES for CATSPERZ Gene
- Kidney(4.1)
No Expression Related Data Available
Primer Products
-
OriGene qPCR primer pairs for CATSPERZ
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CATSPERZ Gene
Orthologs for CATSPERZ Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | TEX40 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | TEX40 34 |
|
||
| cow (Bos Taurus) |
Mammalia | TEX40 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Tex40 34 35 |
|
||
| Catsperz 16 |
|
- Species where no ortholog for CATSPERZ was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for CATSPERZ Gene
No data available for Paralogs for CATSPERZ Gene
Variants for CATSPERZ Gene
| SNP ID | Clin | Chr 11 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1001840955 | -- | 64,304,310(+) | ACCAC(C/T)GCCCT | intron-variant, upstream-variant-2KB | |
| rs1001907775 | -- | 64,299,628(+) | CGCTG(C/G)CCCGC | nc-transcript-variant, upstream-variant-2KB, reference, missense | |
| rs1002963449 | -- | 64,299,254(+) | TTGGG(A/G)TTTGA | intron-variant, upstream-variant-2KB | |
| rs1003444081 | -- | 64,302,908(+) | TTTTA(G/T)TTTTT | intron-variant | |
| rs1003496263 | -- | 64,299,053(+) | AAGAA(A/G)AAAAA | intron-variant, upstream-variant-2KB |
Gene Damage Index Score:
3.96;
59.85% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CATSPERZ Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CATSPERZ
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CATSPERZ Gene
Disorders for CATSPERZ Gene
Relevant External Links for CATSPERZ
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- CATSPERZ
No disorders were found for CATSPERZ Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CATSPERZ Gene
Publications for CATSPERZ Gene
- CatSperIP regulates the structural continuity of sperm Ca(2+) signaling domains and is required for normal fertility. (PMID: 28226241) Chung J.J. … Clapham D.E. (Elife 2017) 2 3 64
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 3 4 64
- Low frequency of ESRRA-C11orf20 fusion gene in ovarian carcinomas. (PMID: 24504521) Micci F. … Heim S. (PLoS Biol. 2014) 3 64
- ESRRA-C11orf20 is a recurrent gene fusion in serous ovarian carcinoma. (PMID: 21949640) Salzman J. … Brown P.O. (PLoS Biol. 2011) 3 64
- A strategy for precise and large scale identification of core fucosylated glycoproteins. (PMID: 19139490) Jia W. … Qian X.H. (Mol. Cell. Proteomics 2009) 4 64
Products for CATSPERZ Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for CATSPERZ
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for CATSPERZ
- Search Origene for MassSpec and Protein Over-expression Lysates for CATSPERZ
- Origene Custom Protein Services for CATSPERZ
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CATSPERZ
- Browse OriGene Inhibitory RNA Products For CATSPERZ
- OriGene qPCR primer pairs for CATSPERZ
- OriGene CRISPR knockouts for CATSPERZ
- OriGene ORF clones in human for CATSPERZ
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CATSPERZ
- GenScript: Next-day shipping cDNA ORF clone for CATSPERZ in any vector
- GenScript Custom Purified and Recombinant Proteins Services for CATSPERZ
- GenScript Custom Assay Services for CATSPERZ
- GenScript Custom overexpressing Cell Line Services for CATSPERZ
- Browse GenScript CRISPR for CATSPERZ
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for CATSPERZ
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Invitrogen Antibodies for CATSPERZ
- ViGene Biosciences adenoviral particle packaged cDNA for CATSPERZ gene
- ViGene Biosciences lentiviral particle packaged cDNA for CATSPERZ gene
- ViGene Biosciences ready-to-package AAV shRNAs for CATSPERZ gene
- Search ViGene Biosciences for CATSPERZ
- Horizon Cell Lines for CATSPERZ
- Cyagen custom Knockout/knockin (KOKI) mouse models for CATSPERZ
- VectorBuilder custom plasmid, inducible vectors for CATSPERZ
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CATSPERZ
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CATSPERZ Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer