CATSPER1 Gene
protein-coding GIFtS: 52
GCID: GC11M065784
|
|
cation channel, sperm associated 1
| |
Aliases
for CATSPER1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Cation Channel, Sperm Associated 11 2 | | Cation Channel Sperm-Associated Protein 12 | | CATSPER1 2 5 | | Sperm Ion Channel2 | | HCatSper1 | | Sperm-Associated Cation Channel 12 | | SPGF72 | | CatSper13 |
Export aliases for CATSPER1 gene to outside databasesPrevious GC identifers: GC11M068318 GC11M067465 GC11M066034 GC11M065559 GC11M065540 GC11M062110 |
Summaries
for CATSPER1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CATSPER1:
Calcium ions play a primary role in the regulation of sperm motility. This gene belongs to a family of putative cationchannels that are specific to spermatozoa and localize to the flagellum. The protein family features a single repeatwith six membrane-spanning segments and a predicted calcium-selective pore region. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: CTSR1_HUMAN, Q8NEC5Function: Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responsesessential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards theoocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha =PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards morephysiological, negative membrane potentials; it is not mediated by metabotropic receptors and second messengers. Spermcapacitation enhances the effect of progesterone by providing additional negative shift. Also activated by theelevation of intracellular pH
Gene Wiki entry for CATSPER1 (CatSper1)
|
Genomic Views
for CATSPER1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_167190.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CATSPER1 gene promoter:
Max1 NF-1/L NF-1 Elk-1 Pax-5 E47 STAT3 Hand1 FOXO1a FOXO1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CATSPER1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CATSPER1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q12.1 Ensembl cytogenetic band: 11q13.1 HGNC cytogenetic band: 11q12.1CATSPER1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M065784: view genomic region
(about GC identifiers)
Start:
|
65,784,223 bp from pter |
End:
|
65,793,988 bp from pter |
Size:
|
9,766 bases |
Orientation:
|
minus strand |
|
Proteins
for CATSPER1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CTSR1_HUMAN, Q8NEC5 (See
protein sequence)Recommended Name: Cation channel sperm-associated protein 1 Size: 780 amino acids; 90091 Da
Subunit: Heterotetramer; possibly composed of CATSPER1, CATSPER2, CATSPER3 and CATSPER4 (Potential). Component of theCatSper complex. Interacts with CATSPER3 and CATSPER4 (By similarity). Interacts with Ca(v)3.3/CACNA1I, leading tosuppress T-type calcium channel activity
Subcellular location: Cell projection, cilium, flagellum membrane; Multi-pass membrane protein. Note=Specificallylocated in the principal piece of sperm tail
Developmental stage: Expressed meiotically and post-meiotically
Secondary accessions: Q96P76Explore the universe of human proteins at neXtProt for CATSPER1: NX_Q8NEC5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8NEC5
CATSPER1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_444282.3
ENSEMBL proteins: ENSP00000309052
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
CATSPER1 for ontologies About GeneDecksing
CATSPER1 Antibody Products:
Assay Products for CATSPER1: |
Protein
Domains /
Families
for CATSPER1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CATSPER1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8NEC5ProtoNet protein and cluster: Q8NEC5 UniProtKB/Swiss-Prot: CTSR1_HUMAN, Q8NEC5Similarity: Belongs to the cation channel sperm-associated (TC 1.A.1.19) family |
Function
for CATSPER1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CTSR1_HUMAN, Q8NEC5Function: Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responsesessential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards theoocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha =PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards morephysiological, negative membrane potentials; it is not mediated by metabotropic receptors and second messengers. Spermcapacitation enhances the effect of progesterone by providing additional negative shift. Also activated by theelevation of intracellular pHInduction: Down-regulated in patients lacking sperm motility
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CATSPER1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CATSPER1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CATSPER1 (NM_053054) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CATSPER1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CATSPER1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CATSPER1 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
CATSPER1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for CATSPER1:
Animal Models:
Mouse knock-out Catsper1tm1Clph for CATSPER1
2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Catsper1):
CATSPER1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for CATSPER1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Sodium channels and transporters: inward current | | | 2 | Sweet Taste Signaling | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for CATSPER1
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for CATSPER1
CATSPER1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CATSPER1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/45 Interacting proteins for CATSPER1 (Q8NEC51, 2, 3 ENSP000003090524) via UniProtKB, MINT, STRING, and/or I2D (see all 45)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| EFEMP2 | O959672, 3, ENSP000003099534 | MINT-66532 I2D:
score=3 STRING: ENSP00000309953 | | CACNA1I | Q9P0X41, 3, ENSP000003850194 | EBI-744545,EBI-1220829 I2D:
score=1 STRING: ENSP00000385019 | | CHIC2 | Q9UKJ52, 3, ENSP000002639214 | MINT-68252 I2D:
score=4 STRING: ENSP00000263921 | | KRTAP4-12 | Q9BQ662, 3, ENSP000003775824 | MINT-68285 I2D:
score=4 STRING: ENSP00000377582 | | TRIP6 | Q156542, 3, ENSP000002004574 | MINT-67180 I2D:
score=4 STRING: ENSP00000200457 |
About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0001539 | ciliary or flagellar motility |
IEA | -- | | GO:0006816 | calcium ion transport |
-- | -- | | GO:0007275 | multicellular organismal development |
IEA | -- | | GO:0007283 | spermatogenesis |
IEA | -- | | GO:0007342 | fusion of sperm to egg plasma membrane |
IEA | -- |
CATSPER1 for ontologies About GeneDecksing
|
Drugs & Compounds
for CATSPER1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
CATSPER1 for compounds About GeneDecksing
 Browse Tocris compounds for CATSPER1
1 HMDB Compound for CATSPER1 About this table
1 Novoseek chemical compound relationship for CATSPER1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| calcium |
27.7 |
2 |
16467839 (1) |
Search CenterWatch for drugs/clinical trials and news about CATSPER1 / CTSR1
|
Transcripts
for CATSPER1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CATSPER1 gene: NM_053054.3 Unigene Cluster for CATSPER1: Cation channel, sperm associated 1 Hs.189105 [show with all ESTs]Unigene Representative Sequence: NM_0530542 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000312106(uc001ogt.3) ENST00000529244
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CATSPER1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CATSPER1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CATSPER1 (NM_053054) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CATSPER1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CATSPER1 |
Additional cDNA sequence: AF407333.1 BC032950.2 BC036522.2 1 DOTS entry: DT.100019352 24/29 AceView cDNA sequences (see all 29): AF407333 BI463921 BQ433031 AA416682 BM559902 BU631501 BC036522 BC032950 NM_053054 BU601108 CD635486 BM987175 BG719591 AA416577 CD635482 CD635489 CD635487 AA884212 CD635484 CD635494 CD635493 CD635491 CD635483 CD635492
GeneLoc Exon Structure
|
Expression
for CATSPER1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CATSPER1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACTGAGAAGC
About this image
See CATSPER1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CATSPER1
SOURCE GeneReport for Unigene cluster: Hs.189105
UniProtKB/Swiss-Prot: CTSR1_HUMAN, Q8NEC5Tissue specificity: Testis-specific
SABiosciences Custom PCR Arrays for CATSPER1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CATSPER1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CATSPER1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CATSPER1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CATSPER1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CATSPER1 |
Orthologs
for CATSPER1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for CATSPER1 gene from 2/7 species (see all 7) About this table
ENSEMBL Gene Tree for CATSPER1 (if available)
TreeFam Gene Tree for CATSPER1 (if available) |
Paralogs
for CATSPER1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CATSPER1 gene
- CATSPER22 CATSPER42 CATSPER32
2 SIMAP similar genes for CATSPER1 using alignment to 1 protein entry: CTSR1_HUMAN:SCN5A SCN3A
CATSPER1 for paralogs About GeneDecksing
|
Genomic Variants
for CATSPER1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CATSPER1 (65784223 - 65793988 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CATSPER1: --
Human Gene Mutation Database (HGMD): CATSPER1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CATSPER1 |
|
Disorders
/ Diseases
for CATSPER1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CATSPER1 for disorders About GeneDecksing
OMIM gene information: 606389
OMIM disorders: 612997
UniProtKB/Swiss-Prot: CTSR1_HUMAN, Q8NEC5
Defects in CATSPER1 are the cause of spermatogenic failure type 7 (SPGF7) [MIM:612997]. An infertilitydisorder characterized by non-motile sperm or sperm motility below the normal threshold, low sperm count, increasedabnormally structured spermatozoa, and reduced semen volume
4  diseases for CATSPER1: About MalaCardsmale infertility rhinotracheitis infertility spermatogenic failure
1 disease from the University of Copenhagen DISEASES database for CATSPER1:Male infertility Export disorders for CATSPER1 gene to outside databases
|
Publications
for CATSPER1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CATSPER1 gene, integrated from 9 sources (see all 23):
(articles sorted by number of sources associating them with CATSPER1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A sperm ion channel required for sperm motility and male fertility. (PubMed id 11595941)1, 2, 3 Ren D.... Clapham D.E. (2001)
- The expression and significance of CATSPER1 in human testis and ejaculated spermatozoa. (PubMed id 16625279)1, 2, 9 Li H.-G.... Xiong C.-L. (2006)
- Human male infertility caused by mutations in the CATSPER1 channel protein. (PubMed id 19344877)1, 2, 9 Avenarius M.R....Smith R.J. (2009)
- Progesterone activates the principal Ca2+ channel of human sperm. (PubMed id 21412339)1, 2 Lishko P.V.... Kirichok Y. (2011)
- The CatSper channel mediates progesterone-induced Ca2+ influx in human sperm. (PubMed id 21412338)1, 2 Strunker T.... Kaupp U.B. (2011)
- Association of Catsper1 or -2 with Ca(v)3.3 leads to suppression of T-type calcium channel activity. (PubMed id 16740636)1, 2 Zhang D.... Gopalakrishnan M. (2006)
- International Union of Pharmacology. L. Nomenclature and structure-function relationships of CatSper and two-pore channels. (PubMed id 16382101)1, 3 Clapham D.E. and Garbers D.L. (2005)
- CatSper gene expression in postnatal development of mouse testis and in subfertile men with deficient sperm motility. (PubMed id 14688170)1, 2 Nikpoor P.... Tiraihi T. (2004)
- A voltage-gated ion channel expressed specifically in spermatozoa. (PubMed id 11675491)1, 3 Quill T.A.... Garbers D.L. (2001)
- Expression of CatSper family transcripts in the mouse testis during post-natal development and human ejaculated spermatozoa: relationship to sperm motility. (PubMed id 17347248)2, 9 Li H.-G.... Xiong C.-L. (2007)
|
External Searches for CATSPER1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CATSPER1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CATSPER1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CATSPER1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CATSPER1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CATSPER1 gene:
Search GeneIP for patents involving CATSPER1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CATSPER1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CATSPER1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CATSPER1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CATSPER1 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CATSPER1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CATSPER1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CATSPER1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CATSPER1 | | OriGene Custom Protein Services for CATSPER1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CATSPER1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CATSPER1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CATSPER1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CATSPER1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CATSPER1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CATSPER1 |
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 | | | CATSPER1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CATSPER1 |
|  |  |  | | | | Search ThermoFisher Antibodies for CATSPER1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CATSPER1 |
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