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Aliases for CATIP Gene

Aliases for CATIP Gene

  • Ciliogenesis Associated TTC17 Interacting Protein 2 3
  • C2orf62 3 4
  • Ciliogenesis-Associated TTC17-Interacting Protein 3
  • Chromosome 2 Open Reading Frame 62 2

External Ids for CATIP Gene

Previous Symbols for CATIP Gene

  • C2orf62

Summaries for CATIP Gene

GeneCards Summary for CATIP Gene

CATIP (Ciliogenesis Associated TTC17 Interacting Protein) is a Protein Coding gene.

UniProtKB/Swiss-Prot for CATIP Gene

  • Plays a role in primary ciliogenesis by modulating actin polymerization.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CATIP Gene

Genomics for CATIP Gene

Genomic Location for CATIP Gene

Start:
218,356,856 bp from pter
End:
218,368,110 bp from pter
Size:
11,255 bases
Orientation:
Plus strand

Genomic View for CATIP Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CATIP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CATIP Gene

No data available for Regulatory Elements for CATIP Gene

Proteins for CATIP Gene

  • Protein details for CATIP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z7H3-CATIP_HUMAN
    Recommended name:
    Ciliogenesis-associated TTC17-interacting protein
    Protein Accession:
    Q7Z7H3
    Secondary Accessions:

    Protein attributes for CATIP Gene

    Size:
    387 amino acids
    Molecular mass:
    43900 Da
    Quaternary structure:
    • Interacts with TTC17.

neXtProt entry for CATIP Gene

Proteomics data for CATIP Gene at MOPED

Post-translational modifications for CATIP Gene

No Post-translational modifications

Other Protein References for CATIP Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CATIP Gene

Domains for CATIP Gene

Protein Domains for CATIP Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

CATIP_HUMAN
Family:
  • Belongs to the CATIP family.:
    • Q7Z7H3
genes like me logo Genes that share domains with CATIP: view

No data available for Gene Families for CATIP Gene

Function for CATIP Gene

Molecular function for CATIP Gene

UniProtKB/Swiss-Prot Function: Plays a role in primary ciliogenesis by modulating actin polymerization.

Gene Ontology (GO) - Molecular Function for CATIP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 24475127
GO:0005516 calmodulin binding IBA --
genes like me logo Genes that share ontologies with CATIP: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CATIP Gene

Localization for CATIP Gene

Subcellular locations from UniProtKB/Swiss-Prot for CATIP Gene

Nucleus. Cytoplasm. Cell membrane. Cytoplasm, cytoskeleton. Note=Colocalized with TTC17 at F-actin rich zones and at dynamic plasma membrane protrusions.

Gene Ontology (GO) - Cellular Components for CATIP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 24475127
GO:0005737 cytoplasm IDA 24475127
GO:0005886 plasma membrane IDA 24475127
GO:0015629 actin cytoskeleton IDA 24475127
genes like me logo Genes that share ontologies with CATIP: view

Pathways for CATIP Gene

SuperPathways for CATIP Gene

No Data Available

Gene Ontology (GO) - Biological Process for CATIP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0030041 actin filament polymerization IMP 24475127
GO:0044782 cilium organization IMP 24475127
genes like me logo Genes that share ontologies with CATIP: view

No data available for Pathways by source for CATIP Gene

Transcripts for CATIP Gene

mRNA/cDNA for CATIP Gene

Alternative Splicing Database (ASD) splice patterns (SP) for CATIP Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10
SP1: - - -
SP2: - - -
SP3:
SP4:

Relevant External Links for CATIP Gene

GeneLoc Exon Structure for
CATIP
ECgene alternative splicing isoforms for
CATIP

Expression for CATIP Gene

mRNA expression in normal human tissues for CATIP Gene

mRNA differential expression in normal tissues according to GTEx for CATIP Gene

This gene is overexpressed in Testis (7.5), Whole Blood (5.7), Kidney - Cortex (4.8), Fallopian Tube (4.3), and Thyroid (4.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CATIP Gene

mRNA Expression by UniProt/SwissProt for CATIP Gene

Q7Z7H3-CATIP_HUMAN
Tissue specificity: Strongly expressed in round and elongating spermatids, weakly in pachytene spermatocytes. Expressed in Leydig cells (at protein level). Expressed in testis, placenta, prostate and lung, and moderately in ovary and brain.
genes like me logo Genes that share expressions with CATIP: view

Orthologs for CATIP Gene

This gene was present in the common ancestor of chordates.

Orthologs for CATIP Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C2orf62 37
  • 99 (a)
OneToOne
CATIP 36
  • 99.48 (n)
  • 98.97 (a)
cow
(Bos Taurus)
Mammalia C2orf62 37
  • 79 (a)
OneToOne
CATIP 36
  • 84.96 (n)
  • 78.89 (a)
dog
(Canis familiaris)
Mammalia C2orf62 37
  • 72 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm216 16
Gm216 37
  • 51 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C2orf62 37
  • 51 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC690437 36
  • 78.66 (n)
  • 75.4 (a)
chicken
(Gallus gallus)
Aves C2orf62 37
  • 42 (a)
OneToOne
CATIP 36
  • 54.44 (n)
  • 43.84 (a)
lizard
(Anolis carolinensis)
Reptilia C2orf62 37
  • 44 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100495462 36
  • 55.52 (n)
  • 44.86 (a)
zebrafish
(Danio rerio)
Actinopterygii C6H2orf62 37
  • 40 (a)
OneToOne
catip 36
  • 54.12 (n)
  • 44.75 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 37 (a)
OneToOne
Species with no ortholog for CATIP:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CATIP Gene

ENSEMBL:
Gene Tree for CATIP (if available)
TreeFam:
Gene Tree for CATIP (if available)

Paralogs for CATIP Gene

No data available for Paralogs for CATIP Gene

Variants for CATIP Gene

Sequence variations from dbSNP and Humsavar for CATIP Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs4381772 -- 218,361,589(+) catca(A/G)atatg intron-variant
rs4674296 -- 218,360,439(+) GCCAC(A/C/T)GTGCC intron-variant
rs4674297 -- 218,364,424(+) TCAGC(A/G)AGATG intron-variant
rs4674298 -- 218,365,824(+) CTCTC(A/T)GTCTC intron-variant
rs6723716 -- 218,363,033(+) GGGAA(C/T)GGGGC intron-variant

Relevant External Links for CATIP Gene

HapMap Linkage Disequilibrium report
CATIP

No data available for Structural Variations from Database of Genomic Variants (DGV) for CATIP Gene

Disorders for CATIP Gene

No disorders were found for CATIP Gene.

No data available for UniProtKB/Swiss-Prot for CATIP Gene

Publications for CATIP Gene

  1. C2orf62 and TTC17 Are Involved in Actin Organization and Ciliogenesis in Zebrafish and Human. (PMID: 24475127) Bontems F. … Lane L. (PLoS ONE 2014) 2 3 4
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for CATIP Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate CATIP
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for CATIP
    • Block miRNA regulation of CATIP using miScript Target Protectors

    Sources for CATIP Gene

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