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Aliases for CATIP Gene

Aliases for CATIP Gene

  • Ciliogenesis Associated TTC17 Interacting Protein 2 3 5
  • C2orf62 3 4
  • Chromosome 2 Open Reading Frame 62 2

External Ids for CATIP Gene

Previous HGNC Symbols for CATIP Gene

  • C2orf62

Previous GeneCards Identifiers for CATIP Gene

  • GC02P219222

Summaries for CATIP Gene

GeneCards Summary for CATIP Gene

CATIP (Ciliogenesis Associated TTC17 Interacting Protein) is a Protein Coding gene. GO annotations related to this gene include calmodulin binding.

UniProtKB/Swiss-Prot for CATIP Gene

  • Plays a role in primary ciliogenesis by modulating actin polymerization.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CATIP Gene

Genomics for CATIP Gene

Regulatory Elements for CATIP Gene

Enhancers for CATIP Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CATIP on UCSC Golden Path with GeneCards custom track

Promoters for CATIP Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CATIP on UCSC Golden Path with GeneCards custom track

Genomic Location for CATIP Gene

Chromosome:
2
Start:
218,356,832 bp from pter
End:
218,368,110 bp from pter
Size:
11,279 bases
Orientation:
Plus strand

Genomic View for CATIP Gene

Genes around CATIP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CATIP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CATIP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CATIP Gene

Proteins for CATIP Gene

  • Protein details for CATIP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z7H3-CATIP_HUMAN
    Recommended name:
    Ciliogenesis-associated TTC17-interacting protein
    Protein Accession:
    Q7Z7H3

    Protein attributes for CATIP Gene

    Size:
    387 amino acids
    Molecular mass:
    43900 Da
    Quaternary structure:
    • Interacts with TTC17.

neXtProt entry for CATIP Gene

Proteomics data for CATIP Gene at MOPED

Post-translational modifications for CATIP Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CATIP Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CATIP Gene

Domains & Families for CATIP Gene

Protein Domains for CATIP Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q7Z7H3

UniProtKB/Swiss-Prot:

CATIP_HUMAN :
  • Belongs to the CATIP family.
Family:
  • Belongs to the CATIP family.
genes like me logo Genes that share domains with CATIP: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for CATIP Gene

Function for CATIP Gene

Molecular function for CATIP Gene

UniProtKB/Swiss-Prot Function:
Plays a role in primary ciliogenesis by modulating actin polymerization.

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CATIP Gene

Localization for CATIP Gene

Subcellular locations from UniProtKB/Swiss-Prot for CATIP Gene

Nucleus. Cytoplasm. Cell membrane. Cytoplasm, cytoskeleton. Note=Colocalized with TTC17 at F-actin rich zones and at dynamic plasma membrane protrusions.

Gene Ontology (GO) - Cellular Components for CATIP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015629 actin cytoskeleton IDA 24475127
genes like me logo Genes that share ontologies with CATIP: view

No data available for Subcellular locations from COMPARTMENTS for CATIP Gene

Pathways & Interactions for CATIP Gene

SuperPathways for CATIP Gene

No Data Available

Gene Ontology (GO) - Biological Process for CATIP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0044782 cilium organization IMP 24475127
genes like me logo Genes that share ontologies with CATIP: view

No data available for Pathways by source and SIGNOR curated interactions for CATIP Gene

Drugs & Compounds for CATIP Gene

No Compound Related Data Available

Transcripts for CATIP Gene

mRNA/cDNA for CATIP Gene

Alternative Splicing Database (ASD) splice patterns (SP) for CATIP Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10
SP1: - - -
SP2: - - -
SP3:
SP4:

Relevant External Links for CATIP Gene

GeneLoc Exon Structure for
CATIP
ECgene alternative splicing isoforms for
CATIP

Expression for CATIP Gene

mRNA expression in normal human tissues for CATIP Gene

mRNA differential expression in normal tissues according to GTEx for CATIP Gene

This gene is overexpressed in Testis (x7.5), Whole Blood (x5.7), Kidney - Cortex (x4.8), Fallopian Tube (x4.3), and Thyroid (x4.2).

Protein differential expression in normal tissues from HIPED for CATIP Gene

This gene is overexpressed in Bone marrow stromal cell (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CATIP Gene



mRNA Expression by UniProt/SwissProt for CATIP Gene

Q7Z7H3-CATIP_HUMAN
Tissue specificity: Strongly expressed in round and elongating spermatids, weakly in pachytene spermatocytes. Expressed in Leydig cells (at protein level). Expressed in testis, placenta, prostate and lung, and moderately in ovary and brain.
genes like me logo Genes that share expression patterns with CATIP: view

Protein tissue co-expression partners for CATIP Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for CATIP Gene

Orthologs for CATIP Gene

This gene was present in the common ancestor of chordates.

Orthologs for CATIP Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia CATIP 35
  • 84.96 (n)
  • 78.89 (a)
C2orf62 36
  • 79 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia CATIP 35
  • 99.48 (n)
  • 98.97 (a)
C2orf62 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC690437 35
  • 78.66 (n)
  • 75.4 (a)
dog
(Canis familiaris)
Mammalia C2orf62 36
  • 72 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C2orf62 36
  • 51 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm216 36
  • 51 (a)
OneToOne
chicken
(Gallus gallus)
Aves CATIP 35
  • 54.44 (n)
  • 43.84 (a)
C2orf62 36
  • 42 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C2orf62 36
  • 44 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100495462 35
  • 55.52 (n)
  • 44.86 (a)
zebrafish
(Danio rerio)
Actinopterygii catip 35
  • 54.12 (n)
  • 44.75 (a)
C6H2orf62 36
  • 40 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 37 (a)
OneToOne
Species with no ortholog for CATIP:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CATIP Gene

ENSEMBL:
Gene Tree for CATIP (if available)
TreeFam:
Gene Tree for CATIP (if available)

Paralogs for CATIP Gene

No data available for Paralogs for CATIP Gene

Variants for CATIP Gene

Sequence variations from dbSNP and Humsavar for CATIP Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs9677109 -- 218,362,370(+) aaaaa(A/G)ggctc intron-variant
rs6757983 -- 218,361,195(+) gtaca(C/T)tggtt intron-variant
rs9784018 -- 218,364,344(+) ATCCT(A/C)CCTCT intron-variant
rs9784095 -- 218,364,329(+) TGGCC(C/T)TAGTA intron-variant
rs11691542 -- 218,362,701(+) CCTGG(G/T)TCCAG intron-variant

Variation tolerance for CATIP Gene

Residual Variation Intolerance Score: 68.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.02; 37.22% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for CATIP Gene

Disorders for CATIP Gene

Relevant External Links for CATIP

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CATIP

No disorders were found for CATIP Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CATIP Gene

Publications for CATIP Gene

  1. C2orf62 and TTC17 Are Involved in Actin Organization and Ciliogenesis in Zebrafish and Human. (PMID: 24475127) Bontems F. … Lane L. (PLoS ONE 2014) 2 3 4 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for CATIP Gene

Sources for CATIP Gene

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