CAT Gene
protein-coding GIFtS : 70
GCID: GC11 P034460
catalase
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Aliasesfor CAT gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Catalase 1 EC 1.11.1.63 8
Export aliases for CAT gene to outside databases Previous GC identifers: GC11P036013 GC11P035138 GC11P034499 GC11P034424 GC11P034417 GC11P034157
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Summariesfor CAT gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for CAT : This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. (provided by RefSeq, Oct 2009) UniProtKB/Swiss-Prot: CATA_HUMAN, P04040 Function : Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects ofhydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells Gene Wiki entry for CAT (Catalase)
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Genomic Viewsfor CAT gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000011.9 NC_018922.1 NT_009237.18 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the CAT gene promoter: GR GR-beta FOXO1a GR-alpha NF-kappaB NF-kappaB1 FOXO1 Other transcription factors Search SABiosciences Chromatin IP Primers for CAT Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat CAT
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 11p13 Ensembl cytogenetic band: 11p13 HGNC cytogenetic band: 11p13 CAT Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 11 GeneLoc Exon Structure
GeneLoc location for GC11P034460: view genomic region
(about GC identifiers )
Start:
34,460,472 bp from pter
End:
34,493,609 bp from pter
Size:
33,138 bases
Orientation:
plus strand
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Proteinsfor CAT gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: CATA_HUMAN, P04040 (See
protein sequence )Recommended Name: Catalase Size : 527 amino acids; 59756 Da
Cofactor : Heme group
Cofactor : NADP
Subunit : Homotetramer
Subcellular location : Peroxisome
6 PDB 3D structures from and Proteopedia for CAT :1DGB (3D)
  1DGF (3D)
  1DGG (3D)
  1DGH (3D)
  1F4J (3D)
  1QQW (3D)
 
Secondary accessions : A8K6C0 B2RCZ9 D3DR07 Q2M1U4 Q4VXX5 Q9BWT9 Q9UC85Explore the universe of human proteins at neXtProt for CAT: NX_P04040 Post-translational modifications:
The N-terminus is blocked1
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_P04040 4/37 DME Specific Peptides for CAT (P04040 ) (see all 37 )CAT Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_001743.1 ENSEMBL proteins: ENSP00000241052 Reactome Protein details: P04040 Human Recombinant Protein Products: Gene Ontology (GO): 5/10 cellular component terms (GO ID links to tree view) (see all 10 ): About this table
CAT for ontologies About GeneDecksing CAT Antibody Products: Assay Products for CAT:
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Protein
Domains / Familiesfor CAT gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
CAT for domains About GeneDecksing 5/7 InterPro domains/families (see all 7 ):
Graphical View of Domain Structure for InterPro Entry P04040 ProtoNet protein and cluster: P04040
1 Blocks protein family : IPB002226 Catalase UniProtKB/Swiss-Prot: CATA_HUMAN, P04040 Similarity : Belongs to the catalase family
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Functionfor CAT gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: CATA_HUMAN, P04040 Function : Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects ofhydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells Catalytic activity : 2 H(2)O(2) = O(2) + 2 H(2)O
Genatlas biochemistry entry for CAT : catalase,60kDa,peroxisomal,expressed in erythrocytes,liver,kidney,catabolic pathway of activated oxygen species,free radical detoxification Enzyme Number (IUBMB): EC 1.11.1.6 1 2 Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for CAT (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for CATOriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: CAT (NM_000019 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CAT Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat CAT
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAT
Gene Ontology (GO): 10 molecular function terms (GO ID links to tree view) (see first 5 ): About this table
CAT for ontologies About GeneDecksing 2 GenomeRNAi human phenotypes for CAT :Animal Models: Mouse knock-out Cat tm1Ysh for CAT 4 MGI mutant phenotypes (inferred from 6 alleles ) (MGI details for Cat) :
CAT for phenotypes About GeneDecksing
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Pathways & Interactionsfor CAT gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Unified GeneCards pathways  - 5/15 super-pathways (see all 15 ) About this table See pathways by source Super-pathway contained gene-specific pathways 1 Purine metabolism 2 Metabolism 3 Doxorubicin Pathway, Pharmacokinetics 4 Tryptophan metabolism 5 Glucose / Energy Metabolism
Pathway sources See GeneCards unified pathways Show all pathways 1
Cell Signaling Technology (CST) Pathway for CAT 5/8 BioSystems Pathways for CAT (see all 8 ) 4
Reactome Pathways for CAT 3 PharmGKB Pathways for CAT 4
Kegg Pathways (Kegg details for CAT) :
CAT for pathways About GeneDecksing Interactions: SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CAT STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)5/62 Interacting proteins for CAT (P04040 2 , 3 ENSP00000241052 4 ) via UniProtKB, MINT, STRING , and/or I2D (see all 62 )About this table Gene Ontology (GO): 5/25 biological process terms (GO ID links to tree view) (see all 25 ): About this table
CAT for ontologies About GeneDecksing
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Drugs & Compoundsfor CAT gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section
CAT for compounds About GeneDecksing Browse Tocris compounds for CAT 10/11 HMDB Compounds for CAT (see all 11 ) About this table 2 DrugBank Compounds for CAT About this table 10/146 Novoseek chemical compound relationships for CAT gene (see all 146 ) About this table
Compound
-log (P-Val)
Hits
PubMed IDs for Articles with Shared Sentences (# sentences)
superoxide
96.5
4472
2313035 (6), 17240813 (5), 20016428 (5), 7551811 (5) (see all 99 )
h2o2
94.6
1885
9389716 (6), 2066646 (5), 8151246 (5), 7541472 (5) (see all 99 )
oxygen
89.4
716
10628300 (7), 8720898 (4), 11368853 (4), 8082230 (3) (see all 99 )
3-amino-1,2,4-triazole
88.1
229
11829410 (3), 12681527 (3), 1540380 (3), 8264727 (2) (see all 99 )
malondialdehyde
87.7
1211
18778500 (5), 17319275 (5), 17190187 (5), 16112416 (4) (see all 99 )
bathocuproine
87.6
60
1846358 (1), 10547184 (1), 11714440 (1), 12016160 (1) (see all 59 )
ascorbic acid
83.7
611
10525278 (6), 15109571 (6), 17319275 (5), 17190187 (5) (see all 99 )
xanthine
82.1
164
16130269 (3), 16112416 (2), 17571208 (2), 8710749 (2) (see all 99 )
n acetylcysteine
81.8
324
11440976 (4), 9437207 (3), 16984740 (3), 15667587 (3) (see all 99 )
deferoxamine
81.3
167
11316574 (3), 1647676 (3), 1958348 (2), 7672482 (2) (see all 99 )
1 PharmGKB related drug/compound annotation for CAT gene About this table Search CenterWatch for drugs/clinical trials and news about CAT / CATA
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Transcriptsfor CAT gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for CAT gene: NM_001752.3 Unigene Cluster for CAT:
Catalase Hs.502302 [show with all ESTs ] Unigene Representative Sequence: NM_001752 5 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000241052 (uc009ykc.1 uc001mvm.3 ) ENST00000528104 ENST00000530343 ENST00000525707 ENST00000534710 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for CAT (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for CATOriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: CAT (NM_000019 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CAT Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat CAT
Additional cDNA sequence: AK022134.1 AK291585.1 AK310184.1 AK315350.1 AY028632.1 BC027300.1 BC110398.1 BC112217.1 BC112219.1 X04076.1
23 DOTS entries : DT.219562 DT.100819495
DT.95261355 DT.100819489 DT.219561 DT.92453028 DT.97835365 DT.120738830 DT.219557 DT.95261357 DT.100819488 DT.100819491 DT.120738832 DT.449665 DT.92406951 DT.100819490 DT.219563 DT.75112267 DT.92453018 DT.95261354 DT.99970908 DT.100738129 DT.97858318 24/412 AceView cDNA sequences (see all 412 ):
AW768666 AA864685 AW440886 AW069129 N77183 BM126827 BG741847 AW514043 BU682877 BQ229200 BQ016836 BQ948440 AL545053 AA379512 BM559223 CR591917 AI190981 BG740929 AI986210 AW955654 BF593978 AI753159 CB162046 BE045822 GeneLoc Exon Structure 5/12 Alternative Splicing Database (ASD) splice patterns (SP) for CAT (see all 12 ) About this scheme ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c ^ 8a · 8b · 8c ^ 9a · 9b · 9c · 9d ^ 10 ^ 11a · 11b · 11c ^ 12 ^ SP1 :                                 -   -   -         -         SP2 :                                 -   -   -         -     -     SP3 :                                 -   -   -         -     -     SP4 :         -       -                                       SP5 :                                 -   -   -                
ExUns: 13a · 13b SP1 :     SP2 :     SP3 :     SP4 :     SP5 :    
ECgene alternative splicing isoforms for CAT
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Expression for CAT gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section CAT expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: GCTTAATGTT
About this image CAT expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table See CAT Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for CAT SOURCE GeneReport for Unigene cluster: Hs.502302 SABiosciences Expression via Pathway-Focused PCR Arrays including CAT (see all 6 ): Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for CATBrowse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat CAT QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat CAT QIAGEN QuantiFast Probe-based Assays in human , mouse , rat CAT In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAT
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Orthologsfor CAT gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the last universal common ancestor (LUCA).
Orthologs for CAT gene from 11/40 species (see all 40 ) About this table
ENSEMBL Gene Tree for CAT (if available)TreeFam Gene Tree for CAT (if available)
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Paralogsfor CAT gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section --
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Genomic Variantsfor CAT gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 11 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for CAT (34460472 - 34493609 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for CAT: -- Human Gene Mutation Database (HGMD) : CAT SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing CAT
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Disorders
/ Diseasesfor CAT gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Novoseek ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
CAT for disorders About GeneDecksing
OMIM gene information: 115500
OMIM disorders : --UniProtKB/Swiss-Prot: CATA_HUMAN, P04040
Defects in CAT are the cause of acatalasemia (ACATLAS) [MIM:614097]. A metabolic disorder characterized by absence of catalase activity in red cells and is often associated with ulcerating oral lesions 20/352 diseases for CAT (see all 352 ): About MalaCards systemic lupus erythematosus lupus erythematosus rheumatoid arthritis peroxisomal biogenesis disorder peroxisome biogenesis disorders post-traumatic stress disorder pityriasis versicolor maple syrup urine disease pthirus pubis infestation werdnig-hoffmann disease estrogen-receptor negative breast cancer alzheimer's disease chondrodysplasia punctata glycogen storage disease type ia spermatic cord torsion rhizomelic chondrodysplasia punctata avascular necrosis of femoral head obsessive-compulsive disorder hermansky-pudlak syndrome mitral valve prolapse 10/92 Novoseek disease relationships for CAT gene (see all 92 ) About this table
Disease
-log (P-Val)
Hits
PubMed IDs for Articles with Shared Sentences (# sentences)
acatalasemia
77.5
12
19122680 (2), 1999334 (2), 11001624 (1), 11197178 (1) (see all 8 )
hypocatalasemia
71.2
1
14996832 (1)
zellweger syndrome
71.2
10
1946426 (3), 1651504 (1), 9408912 (1), 8931469 (1) (see all 7 )
peroxisomal disorders
68.3
2
2295968 (1), 8463903 (1)
cell damage
67.2
32
11729237 (2), 19917279 (2), 14675044 (2), 1958348 (1) (see all 27 )
adrenoleukodystrophy neonatal
65
2
7687405 (1), 1689088 (1)
refsum disease infantile
63.9
6
7510868 (2), 9408912 (1), 1689088 (1), 7687405 (1)
peroxisome biogenesis disorders
59
4
10567403 (1), 15184617 (1), 10960480 (1)
granulomatous disease chronic
57.4
7
9864180 (1), 15135177 (1), 1370724 (1), 12706409 (1) (see all 7 )
vitiligo
55.4
66
11837458 (7), 19439879 (4), 18315617 (4), 17433173 (3) (see all 29 )
Genatlas disease: CAT acatalasia Genetic Association Database (GAD): CAT Human Genome Epidemiology (HuGE) Navigator: CAT (269 documents) Export disorders for CAT gene to outside databases
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Publicationsfor CAT gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for CAT gene, integrated from 9 sources (see all 3563 ): (articles sorted by number of sources associating them with CAT) Utopia : connect your pdf to the dynamic world of online information
Association of CAT polymorphisms with catalase activity and exposure to environmental oxidative stimuli. (PubMed id 16298864) 1 , 4, 9 Nadif R....Kauffmann F. (2005) Genetic association of the catalase gene (CAT) with vitiligo susceptibility. (PubMed id 11837458) 1 , 4, 9 Casp C.B....McCormack W.T. (2002) Genetic polymorphisms of oxidative and antioxidant enzymes and arsenic-related hypertension. (PubMed id 16076760) 1 , 4, 9 Hsueh Y.M....Chen C.J. (2005) [Associative analysis of the connection between mutation C1167T in the catalase gene and polymorphic marker D6S392 nearby the Mn-dependent superoxide dismutase gene with diabetic microangiopathies] (PubMed id 12469627) 1 , 4, 9 Chistiakov D.A....Debabov V.G. (2002) Vulnerability of the human airway epithelium to hyperoxia. Constitutive expression of the catalase gene in human bronchial epithelial cells despite oxidant stress. (PubMed id 8282800) 1 , 2 , 9 Yoo J.-H.... Crystal R.G. (1994) A testing framework for identifying susceptibility genes in the presence of epistasis. (PubMed id 16385446) 1 , 4, 9 Millstein J....Gauderman W.J. (2006) Genetic polymorphisms of GSTT1, GSTM1, GSTP1, MnSOD, and catalase in nonhereditary chronic pancreatitis: evidence of xenobiotic stress and impaired antioxidant capacity. (PubMed id 16047490) 1 , 4, 9 Rahman S.H....McMahon M.J. (2005) Polymorphisms in genes related to oxidative stress (MPO, MnSOD, CAT) and survival after treatment for breast cancer. (PubMed id 15705913) 1 , 4, 9 Ambrosone C.B....Trovato A. (2005) [Search for the association of polymorphic markers for genes coding for antioxidant defense enzymes, with development of diabetic polyneuropathies in patients with type 1 diabetes mellitus] (PubMed id 15125229) 1 , 4, 9 Zotova E.V....Nosikov V.V. (2004) Association of antioxidant enzyme gene polymorphisms and glutathione status with severe acute pancreatitis. (PubMed id 15131792) 1 , 4, 9 Rahman S.H....McMahon M.J. (2004)
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Genome Databases showing CAT gene
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Specialized Databases showing CAT gene (According to PharmGKB ,
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About This Section Patent Information for CAT gene: Search GeneIP for patents involving CAT GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor CAT gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
OriGene Antibodies for CAT OriGene shRNA RFP for CAT OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for CAT OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for CAT OriGene Protein Over-expression Lysate for CAT Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for CAT OriGene 3'-UTR Clone for CAT OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for CAT OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for CAT Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs OriGene Purified Protein for CAT OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for CAT OriGene Custom Protein Services for CAT OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CAT QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing CAT QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat CAT QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat CAT QIAGEN QuantiFast Probe-based Assays in human , mouse , rat CAT QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat CAT
Antibodies & Assays for CAT   (catalase)
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CAT Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAT
ThermoFisher Antibodies for CAT
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat CAT
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