Aliases for CAT Gene
External Ids for CAT Gene
- HGNC: 1516
- Entrez Gene: 847
- Ensembl: ENSG00000121691
- OMIM: 115500
- UniProtKB: P04040
Previous GeneCards Identifiers for CAT Gene
- GC11P036013
- GC11P035138
- GC11P034499
- GC11P034424
- GC11P034417
- GC11P034157
Summaries for CAT Gene
-
This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009]
GeneCards Summary for CAT Gene
CAT (Catalase) is a Protein Coding gene. Diseases associated with CAT include Acatalasemia and Pityriasis Versicolor. Among its related pathways are DNA Damage Response (only ATM dependent) and Innate Immune System. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and enzyme binding.
UniProtKB/Swiss-Prot for CAT Gene
-
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
Additional gene information for CAT Gene
- Monarch Initiative
- Search for CAT at DataMed
- Search for CAT at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CAT Gene
Genomics for CAT Gene
GeneHancer (GH) Regulatory Elements for CAT Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH11I034437 | Promoter/Enhancer | 2.3 | EPDnew Ensembl ENCODE dbSUPER | 580.7 | +0.1 | 88 | 3.1 | HDGF FOXA2 PKNOX1 SMAD1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 | CAT CAPRIN1 NAT10 ELF5 | |
GH11I034404 | Enhancer | 1.5 | FANTOM5 Ensembl ENCODE dbSUPER | 30.7 | -33.7 | -33724 | 0.8 | IRF2 USF1 ZBTB21 JUN MAX BATF FOSL1 ZNF335 DIDO1 ZNF366 | ENSG00000220204 CAT NAT10 ABTB2 CAPRIN1 GC11P034408 | |
GH11I034425 | Enhancer | 1.4 | Ensembl ENCODE dbSUPER | 31.3 | -12.0 | -11969 | 2.5 | PKNOX1 ATF1 FOXA2 DMAP1 ETS1 YY1 SLC30A9 TCF12 ATF7 FOS | CAT ABTB2 CIR1P3 GC11P034408 | |
GH11I034462 | Enhancer | 0.9 | dbSUPER | 37.1 | +24.6 | 24613 | 2.1 | ATF1 FOXA2 MLX ARID4B TCF12 SP5 NFYC PPARG KAT8 MEF2D | CAT ABTB2 ELF5 | |
GH11I034416 | Enhancer | 0.9 | Ensembl dbSUPER | 35.6 | -21.9 | -21933 | 0.5 | CTCF RXRA HLF MAX CEBPB CEBPG EP300 RAD21 YY1 JUND | CAT ABTB2 GC11P034408 CIR1P3 |
Regulatory Element Products
Genomic Locations for CAT Gene
- chr11:34,438,925-34,472,062
- (GRCh38/hg38)
- Size:
- 33,138 bases
- Orientation:
- Plus strand
- chr11:34,460,472-34,493,609
- (GRCh37/hg19)
Genomic View for CAT Gene
- Cytogenetic band:
-
- 11p13 by Ensembl
- 11p13 by Entrez Gene
- 11p13 by HGNC


RefSeq DNA sequence for CAT Gene
Proteins for CAT Gene
-
Protein details for CAT Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P04040-CATA_HUMAN
- Recommended name:
- Catalase
- Protein Accession:
- P04040
- A8K6C0
- B2RCZ9
- D3DR07
- Q2M1U4
- Q4VXX5
- Q9BWT9
- Q9UC85
Protein attributes for CAT Gene
- Size:
- 527 amino acids
- Molecular mass:
- 59756 Da
- Cofactor:
- Name=heme; Xref=ChEBI:CHEBI:30413;
- Cofactor:
- Name=NADP(+); Xref=ChEBI:CHEBI:58349;
- Quaternary structure:
-
- Homotetramer.
Protein Expression for CAT Gene
Selected DME Specific Peptides for CAT Gene
- P04040:
-
- RDLFNAIA
- LQGRLFAY
- PSWTFYIQVMTF
- DKMLQGR
- PERVVHAKG
- TVGPRGP
- GESGSADT
- KRNPQTH
- DLTKVWPH
- DNQGGAPNY
- KFYTEDG
- GNPVGDKLN
- GEAVYCKFHYKTDQGIKNL
- SPDKMLQ
- FIHSQKR
- NPFDLTK
- GAFGYFEVT
- RHRLGPNYL
- DNVTQVR
- WDLVGNNTP
- NYFAEVEQ
- KPKNAIHT
- NGYGSHT
- GNWDLVGNN
- DTHRHRLG
- FEVTHDI
- PVNCPYR
- PESLHQV
- FIQKKAVKNF
- GSADTVRD
- RKRLCENIA
- RVANYQRDGPMC
- RFSTVAG
- GFAVKFYT
- RERIPERVVHA
- AFDPSNMPPGIE
- RDPRGFA
Post-translational modifications for CAT Gene
- The N-terminus is blocked.
- Ubiquitination at posLast=480480
Other Protein References for CAT Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for CAT (Catalase)
- Cell Signaling Technology (CST) Antibodies for CAT (Catalase)
- Novus Biologicals Antibodies for CAT
-
Abcam antibodies for CAT
-
Cloud-Clone Corp. Antibodies for CAT
- Invitrogen Antibodies for CAT
- antibodies-online: Search results for 265 available Catalase Antibodies ranked by validation data
- Compare Top Catalase Antibodies
-
Recommended
- 1 IHC Antibody (anti-rat)
- 2 IP Antibodies (anti-rat)
- 2 IEP Antibodies (anti-rat)
- 6 IHC (p) Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 40 WB Antibodies (anti-rat)
- 1 IP Antibody (anti-mouse)
- 1 IHC Antibody (anti-mouse)
- 2 IEP Antibodies (anti-mouse)
- 6 IHC (p) Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 66 WB Antibodies (anti-mouse)
- 1 FACS Antibody (anti-human)
- 2 RIA Antibodies (anti-human)
- 2 IEP Antibodies (anti-human)
- 3 IP Antibodies (anti-human)
- 4 IHC Antibodies (anti-human)
- 6 IHC (p) Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 134 WB Antibodies (anti-human)
- GeneTex CAT antibody for CAT
-
Santa Cruz Biotechnology (SCBT) Antibodies for CAT
- Sino Biological Antibodies for CAT
Protein Products
-
OriGene Purified Proteins for CAT
- Search Origene for MassSpec and Protein Over-expression Lysates for CAT
- Origene Custom Protein Services for CAT
- Sino Biological Cell Lysates for CAT
- Sino Biological Recombinant Proteins for CAT
- ProSpec Recombinant Proteins for CAT
-
Cloud-Clone Corp. Proteins for CAT
- Search GeneTex for Proteins for CAT
-
ProSci Proteins for CAT
-
Abcam proteins for CAT
Assay Products
- R&D Systems Proteome Profiler Antibody Arrays and other biochemical assays for CAT (Catalase)
-
Cloud-Clone Corp. Assay Kits for CAT
- antibodies-online: Search results for 50 available Catalase Elisa Kits ranked by validation data
- Compare Top Catalase Elisa Kits
-
Recommended
- ABIN2866577
- ABIN411879
- ABIN1000296
- ABIN2815076
- 1 Sheep (Ovine) ELISA Kit
- 8 Rat (Rattus) ELISA Kits
- 2 Rabbit ELISA Kits
- 1 Plant ELISA Kit
- 2 Pig (Porcine) ELISA Kits
- 8 Mouse (Murine) ELISA Kits
- 1 Monkey ELISA Kit
- 1 Mammalian ELISA Kit
- 11 Human ELISA Kits
- 1 Guinea Pig ELISA Kit
- 2 Goat ELISA Kits
- 2 Fish ELISA Kits
- 1 Dog (Canine) ELISA Kit
- 2 Cow (Bovine) ELISA Kits
- 3 Chicken ELISA Kits
-
Abcam assays for CAT
Domains & Families for CAT Gene
Gene Families for CAT Gene
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Disease related genes
- Enzymes
- FDA approved drug targets
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for CAT Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CAT Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P04040- Family:
-
- Belongs to the catalase family.
Function for CAT Gene
Molecular function for CAT Gene
- GENATLAS Biochemistry:
- catalase,60kDa,peroxisomal,expressed in erythrocytes,liver,kidney,catabolic pathway of activated oxygen species,free radical detoxification
- UniProtKB/Swiss-Prot CatalyticActivity:
- 2 H(2)O(2) = O(2) + 2 H(2)O.
- UniProtKB/Swiss-Prot Function:
- Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
Enzyme Numbers (IUBMB) for CAT Gene
Phenotypes From GWAS Catalog for CAT Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0004046 | aminoacylase activity | IEA | -- |
GO:0004096 | catalase activity | TAS | -- |
GO:0004601 | peroxidase activity | IEA | -- |
GO:0005102 | receptor binding | IPI | 20178365 |
GO:0016209 | antioxidant activity | IDA | 10514471 |
Phenotypes for CAT Gene
- MGI mutant phenotypes for CAT:
- inferred from 6 alleles
- GenomeRNAi human phenotypes for CAT:
Animal Models for CAT Gene
- MGI Knock Outs for CAT:
-
- Cat tm1Ysh
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CAT
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CAT gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CAT gene
- Search ViGene Biosciences for CAT
CRISPR Products
-
OriGene CRISPR knockouts for CAT
- genomics-online: gRNA clones - Search results for 35 available Catalase gene related products
- Overview of 35 available Catalase gene related products
- Applied Biological Materials CRISPR for CAT
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CAT
- GenScript: Design CRISPR guide RNA sequences for CAT
miRNA for CAT Gene
- miRTarBase miRNAs that target CAT
miRNA Products
- Search ViGene Biosciences for CAT
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CAT
- Browse OriGene Inhibitory RNA Products For CAT
- genomics-online: shRNA clones - Search results for 35 available Catalase gene related products
- Overview of 35 available Catalase gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for CAT gene
Clone Products
- Sino Biological Human cDNA Clone for CAT
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CAT
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CAT
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for CAT
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for CAT
-
ViGene Biosciences adenoviral particle packaged cDNA for CAT gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CAT gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CAT gene
No data available for Transcription Factor Targets and HOMER Transcription for CAT Gene
Localization for CAT Gene
Subcellular locations from UniProtKB/Swiss-Prot for CAT Gene
- Peroxisome.
- Cytosol (3)
- Vesicles (3)
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005576 | extracellular region | TAS | -- |
GO:0005615 | extracellular space | IEA | -- |
GO:0005739 | mitochondrion | IBA,IEA | -- |
GO:0005758 | mitochondrial intermembrane space | IEA | -- |
GO:0005764 | lysosome | IEA | -- |
Pathways & Interactions for CAT Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Detoxification of Reactive Oxygen Species | ||
2 | Innate Immune System |
.61
|
|
3 | Purine metabolism | ||
4 | Amyotrophic lateral sclerosis (ALS) | ||
5 | Longevity regulating pathway |
Pathways by source for CAT Gene
1 Cell Signaling Technology pathway for CAT Gene
9 BioSystems pathways for CAT Gene
9 Reactome pathways for CAT Gene
3 PharmGKB pathways for CAT Gene
Interacting Proteins for CAT Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000302 | response to reactive oxygen species | IMP | 16644728 |
GO:0001649 | osteoblast differentiation | IDA,HDA | 16210410 |
GO:0001657 | ureteric bud development | IEA | -- |
GO:0001666 | response to hypoxia | IEA | -- |
GO:0001822 | kidney development | IEA | -- |
Drugs & Compounds for CAT Gene
Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
---|---|---|---|---|---|---|
superoxide |
|
11062-77-4 | ||||
Cinnavalininate |
|
|
||||
Hydrogen Ion |
|
|
||||
methanol |
|
67-56-1 |
|
|||
NADP |
|
53-59-8 |
|
Transcripts for CAT Gene
mRNA/cDNA for CAT Gene
- (1) REFSEQ mRNAs :
- (10) Additional mRNA sequences :
- (412) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for CAT
- genomics-online: gRNA clones - Search results for 35 available Catalase gene related products
- Overview of 35 available Catalase gene related products
- Applied Biological Materials CRISPR for CAT
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CAT
- GenScript: Design CRISPR guide RNA sequences for CAT
miRNA Products
- Search ViGene Biosciences for CAT
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CAT
- Browse OriGene Inhibitory RNA Products For CAT
- genomics-online: shRNA clones - Search results for 35 available Catalase gene related products
- Overview of 35 available Catalase gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for CAT gene
Clone Products
- Sino Biological Human cDNA Clone for CAT
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CAT
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CAT
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for CAT
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | · | 8c | ^ | 9a | · | 9b | · | 9c | · | 9d | ^ | 10 | ^ | 11a | · | 11b | · | 11c | ^ | 12 | ^ |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
SP2: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
SP3: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
SP4: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
SP5: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
SP6: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
SP7: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP8: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
SP9: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP10: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP11: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP12: | - |
ExUns: | 13a | · | 13b |
---|---|---|---|
SP1: | |||
SP2: | |||
SP3: | |||
SP4: | |||
SP5: | |||
SP6: | |||
SP7: | |||
SP8: | |||
SP9: | |||
SP10: | |||
SP11: | |||
SP12: |
Expression for CAT Gene
mRNA differential expression in normal tissues according to GTEx for CAT Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CAT Gene
NURSA nuclear receptor signaling pathways regulating expression of CAT Gene:
CATSOURCE GeneReport for Unigene cluster for CAT Gene:
Hs.502302Evidence on tissue expression from TISSUES for CAT Gene
- Liver(4.9)
- Nervous system(4.8)
- Blood(4.7)
- Kidney(4.7)
- Eye(4.5)
- Heart(3.6)
- Lung(3.4)
- Muscle(3.2)
- Skin(2.9)
- Adrenal gland(2.8)
- Bone marrow(2.8)
- Intestine(2.8)
- Pancreas(2.7)
- Spleen(2.7)
- Stomach(2.7)
- Thyroid gland(2.5)
Phenotype-based relationships between genes and organs from Gene ORGANizer for CAT Gene
- ectoderm
- digestive
- head
- mouth
Primer Products
-
OriGene qPCR primer pairs and template standards for CAT
-
OriGene qPCR primer pairs for CAT
- genomics-online: primer clones - Search results for 35 available Catalase gene related products
- Overview of 35 available Catalase gene related products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for CAT Gene
Orthologs for CAT Gene
This gene was present in the common ancestor of eukaryotes.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | CAT 33 34 |
|
||
cow (Bos Taurus) |
Mammalia | CAT 33 34 |
|
||
dog (Canis familiaris) |
Mammalia | CAT 33 34 |
|
||
-- 34 |
|
OneToMany | |||
platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
-- 34 |
|
OneToMany | |||
mouse (Mus musculus) |
Mammalia | Cat 33 16 34 |
|
||
rat (Rattus norvegicus) |
Mammalia | Cat 33 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | CAT 34 |
|
OneToOne | |
chicken (Gallus gallus) |
Aves | CAT 33 34 |
|
||
lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToMany | |
-- 34 |
|
OneToMany | |||
-- 34 |
|
OneToMany | |||
tropical clawed frog (Silurana tropicalis) |
Amphibia | cat.2 33 |
|
||
African clawed frog (Xenopus laevis) |
Amphibia | cat-prov 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | cat 33 34 |
|
||
fruit fly (Drosophila melanogaster) |
Insecta | Cat 35 33 34 |
|
||
CG9314 35 34 |
|
||||
African malaria mosquito (Anopheles gambiae) |
Insecta | CAT1 33 |
|
||
worm (Caenorhabditis elegans) |
Secernentea | ctl-2 33 34 |
|
||
Y54G11A.13 35 |
|
|
|||
ctl-1 34 |
|
OneToMany | |||
ctl-3 34 |
|
OneToMany | |||
A. gosspyii yeast (Ashbya gossypii) |
Saccharomycetes | AGOS_AGL256W 33 |
|
||
K. lactis yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0D11660g 33 |
|
||
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | CTA1 33 34 36 |
|
||
thale cress (Arabidopsis thaliana) |
eudicotyledons | CAT1 33 |
|
||
soybean (Glycine max) |
eudicotyledons | Gma.2444 33 |
|
||
Alicante grape (Vitis vinifera) |
eudicotyledons | Vvi.7958 33 |
|
||
rice (Oryza sativa) |
Liliopsida | Os03g0131200 33 |
|
||
Os.156 33 |
|
||||
barley (Hordeum vulgare) |
Liliopsida | Hv.108 33 |
|
||
wheat (Triticum aestivum) |
Liliopsida | Ta.28032 33 |
|
||
corn (Zea mays) |
Liliopsida | Zm.6357 33 |
|
||
sea squirt (Ciona savignyi) |
Ascidiacea | CSA.4587 34 |
|
OneToOne | |
fission yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | ctt1 33 |
|
||
bread mold (Neurospora crassa) |
Ascomycetes | NCU05169 33 |
|
- Species where no ortholog for CAT was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
Paralogs for CAT Gene
No data available for Paralogs for CAT Gene
Variants for CAT Gene
SNP ID | Clin | Chr 11 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000102164 | -- | 34,471,758(+) | A/T | 3_prime_UTR_variant | |
rs1000148062 | -- | 34,444,358(+) | G/T | intron_variant | |
rs1000162829 | -- | 34,457,096(+) | A/G | intron_variant | |
rs1000189640 | -- | 34,454,111(+) | C/T | intron_variant | |
rs1000307684 | -- | 34,463,809(+) | A/G | intron_variant |
Additional Variant Information for CAT Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CAT Gene
Disorders for CAT Gene

(48) MalaCards diseases for CAT Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, DISEASES, Novoseek, and GeneCards
Disorder | Aliases | PubMed IDs |
---|---|---|
acatalasemia |
|
|
pityriasis versicolor |
|
|
pneumoconiosis |
|
|
urogenital tuberculosis |
|
|
congenital rubella |
|
|
UniProtKB/Swiss-Prot
CATA_HUMAN- Acatalasemia (ACATLAS) [MIM:614097]: A metabolic disorder characterized by a total or near total loss of catalase activity in red cells. It is often associated with ulcerating oral lesions. {ECO:0000269 PubMed:2308162}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Genatlas disease for CAT Gene
Additional Disease Information for CAT
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Publications for CAT Gene
- Gene polymorphisms in association with emerging cardiovascular risk markers in adult women. (PMID: 20078877) Fan AZ … Mokdad AH (BMC medical genetics 2010) 3 22 44 58
- Functional variants in the catalase and myeloperoxidase genes, ambient air pollution, and respiratory-related school absences: an example of epistasis in gene-environment interactions. (PMID: 19897513) Wenten M … Gilliland FD (American journal of epidemiology 2009) 3 22 44 58
- Myeloperoxidase and superoxide dismutase 2 polymorphisms comodulate the risk of hepatocellular carcinoma and death in alcoholic cirrhosis. (PMID: 19731237) Nahon P … Beaugrand M (Hepatology (Baltimore, Md.) 2009) 3 22 44 58
- Detection of catalase as a major protein target of the lipid peroxidation product 4-HNE and the lack of its genetic association as a risk factor in SLE. (PMID: 18606005) D'souza A … Scofield RH (BMC medical genetics 2008) 3 22 44 58
- Ozone, oxidant defense genes, and risk of asthma during adolescence. (PMID: 18048809) Islam T … Gilliland FD (American journal of respiratory and critical care medicine 2008) 3 22 44 58
Products for CAT Gene
- R&D Systems Antibodies for CAT (Catalase)
- Browse R&D Systems for Human Recombinant Proteins
- R&D Systems Proteome Profiler Antibody Arrays and other biochemical assays for CAT (Catalase)
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for CAT
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for CAT
- Search Origene for MassSpec and Protein Over-expression Lysates for CAT
- Origene Custom Protein Services for CAT
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CAT
- Browse OriGene Inhibitory RNA Products For CAT
- OriGene qPCR primer pairs and template standards for CAT
- OriGene qPCR primer pairs for CAT
- OriGene CRISPR knockouts for CAT
- OriGene ORF clones in human for CAT
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CAT
- GenScript: Next-day shipping of latest version cDNA ORF clones for CAT in any vector
- GenScript Custom Purified and Recombinant Proteins Services for CAT
- GenScript Custom Assay Services for CAT
- GenScript Custom overexpressing Cell Line Services for CAT
- GenScript: Design CRISPR guide RNA sequences for CAT
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for CAT
- Cell Signaling Technology (CST) Antibodies for CAT (Catalase)
- Search for Antibodies & Assays
- Sino Biological Human cDNA Clone for CAT
- Sino Biological Recombinant Proteins for CAT
- Sino Biological Cell Lysates for CAT
- Sino Biological Antibodies for CAT
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for CAT
- Novus Biologicals lysates and proteins for CAT
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for CAT
- Abcam proteins for CAT
- Abcam assays for CAT
- Find your target
- Browse Primary Antibodies
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- Browse ELISA Kits
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- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- ProSpec Recombinant Proteins for CAT
- Cloud-Clone Corp. Antibodies for CAT
- Cloud-Clone Corp. Proteins for CAT
- Cloud-Clone Corp. Assay Kits for CAT
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for CAT
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for CAT
- VectorBuilder custom plasmid, inducible vectors for CAT
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CAT
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 265 available Catalase Antibodies ranked by validation data
- Compare Top Catalase Antibodies
- Recommended
- 134 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 6 IHC (p) Antibodies (anti-human)
- 4 IHC Antibodies (anti-human)
- 3 IP Antibodies (anti-human)
- 2 IEP Antibodies (anti-human)
- 2 RIA Antibodies (anti-human)
- 1 FACS Antibody (anti-human)
- 66 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 6 IHC (p) Antibodies (anti-mouse)
- 2 IEP Antibodies (anti-mouse)
- 1 IHC Antibody (anti-mouse)
- 1 IP Antibody (anti-mouse)
- 40 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 6 IHC (p) Antibodies (anti-rat)
- 2 IEP Antibodies (anti-rat)
- 2 IP Antibodies (anti-rat)
- 1 IHC Antibody (anti-rat)
- antibodies-online: Search results for 50 available Catalase Elisa Kits ranked by validation data
- Compare Top Catalase Elisa Kits
- Recommended
- 3 Chicken ELISA Kits
- 2 Cow (Bovine) ELISA Kits
- 1 Dog (Canine) ELISA Kit
- 2 Fish ELISA Kits
- 2 Goat ELISA Kits
- 1 Guinea Pig ELISA Kit
- 11 Human ELISA Kits
- 1 Mammalian ELISA Kit
- 1 Monkey ELISA Kit
- 8 Mouse (Murine) ELISA Kits
- 2 Pig (Porcine) ELISA Kits
- 1 Plant ELISA Kit
- 2 Rabbit ELISA Kits
- 8 Rat (Rattus) ELISA Kits
- 1 Sheep (Ovine) ELISA Kit
- ABIN2815076
- ABIN1000296
- ABIN411879
- ABIN2866577
- antibodies-online: Search results for 26 available Catalase Proteins ranked by validation data
- Compare Top Catalase Proteins
- GeneTex CAT antibody for CAT
- Search GeneTex for Proteins for CAT
- ViGene Biosciences adenoviral particle packaged cDNA for CAT gene
- ViGene Biosciences lentiviral particle packaged cDNA for CAT gene
- ViGene Biosciences ready-to-package AAV shRNAs for CAT gene
- Search ViGene Biosciences for CAT
- Santa Cruz Biotechnology (SCBT) Antibodies for CAT
- Search Santa Cruz Biotechnology (SCBT) for CAT siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CAT
- Search for CAT Antibodies at ProSci
- Custom Antibody Services
- ProSci Proteins for CAT
- Horizon Cell Lines for CAT
- genomics-online: cdna clones - Search results for 35 available Catalase gene related products
- Overview of 35 available Catalase gene related products
- orf clones - Search results for 35 available Catalase gene related products
- Overview of 35 available Catalase gene related products
- genomics-online: gRNA clones - Search results for 35 available Catalase gene related products
- Overview of 35 available Catalase gene related products
- genomics-online: primer clones - Search results for 35 available Catalase gene related products
- Overview of 35 available Catalase gene related products
- genomics-online: shRNA clones - Search results for 35 available Catalase gene related products
- Overview of 35 available Catalase gene related products
Sources for CAT Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew