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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

CASZ1 Gene

protein-coding GIFtS: 45
GCID: GC01M010642

castor zinc finger 1

(Previous names: castor homolog 1, zinc finger (Drosophila) )

Explore 6 diseases affiliated with
CASZ1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Castor Zinc Finger 1¹ ²		Castor Homolog 1, Zinc Finger (Drosophila)¹
SRG¹ ² ³ ⁵		Cst¹
ZNF693¹ ² ³		CAS11²
Castor-Related Protein² ³		Castor Homolog 1, Zinc Finger²
Zinc Finger Protein 693² ³		DJ734G22.1¹
CST² ³		Survival-Related¹
FLJ20321¹		Zinc Finger Protein Castor Homolog 1²
Castor¹		Putative Survival-Related Protein³

External Ids:	HGNC: 26002¹	Entrez Gene: 54897²	Ensembl: ENSG00000130940⁷	OMIM: 609895⁵	UniProtKB: Q86V15³

Export aliases for CASZ1 gene to outside databases

Previous GC identifer: GC01M009850

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CASZ1:

The protein encoded by this gene is a zinc finger transcription factor. The encoded protein may function as a tumor

suppressor, and single nucleotide polymorphisms in this gene are associated with blood pressure variation. Alternative

splicing results in multiple transcript variants that encode different protein isoforms. (provided by RefSeq, Jul

2012)

UniProtKB/Swiss-Prot: CASZ1_HUMAN, Q86V15

Function: Probable transcription factor (By similarity)

Gene Wiki entry for CASZ1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_021937.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the CASZ1 gene promoter:
FOXD3 Nkx2-5 POU3F2 NF-AT AREB6 NF-AT4 SRY NF-AT2 NF-AT3 NF-AT1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CASZ1 promoter sequence

Search SABiosciences Chromatin IP Primers for CASZ1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CASZ1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.22 Ensembl cytogenetic band: 1p36.22 HGNC cytogenetic band: 1p36.22

CASZ1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CASZ1 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M010642: view genomic region (about GC identifiers)

Start:	10,696,661 bp from pter	End:	10,856,707 bp from pter
Size:	160,047 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CASZ1_HUMAN, Q86V15 (See protein sequence)

Recommended Name: Zinc finger protein castor homolog 1

Size: 1759 amino acids; 190069 Da

Subcellular location: Nucleus

Caution: According to PubMed:16322216, another protein (SRG) is encoded on the 3'-UTR of the CASZ1 gene. The existence

of this protein that may play a role in apoptosis is extremely dubious despite the fact it was localized in the

cytoplasm with the help of a polyclonal antibody

Sequence caution: Sequence=ABD14411.1; Type=Erroneous translation; Note=Wrong choice of CDS; Sequence=BAA91089.1;

Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAC85474.1; Type=Erroneous translation;

Note=Wrong choice of CDS;

Secondary accessions: Q078S9 Q2EN02 Q5T9S1 Q6ZNM8 Q8WX49 Q8WX50 Q9BT16 Q9NXC6

Alternative splicing: 2 isoforms: Q86V15-1 Q86V15-2

Explore the universe of human proteins at neXtProt for CASZ1: NX_Q86V15

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q86V15

CASZ1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001073312.1 NP_060236.3

ENSEMBL proteins:

ENSP00000366221 ENSP00000467769 ENSP00000339445

Human Recombinant Protein Products:

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	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: CASZ1 OriGene Custom Protein Services for CASZ1
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	Novus Biologicals CASZ1 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for CASZ1

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	--
GO:0005730	NOT nucleolus	IDA	--
GO:0005737	cytoplasm	IDA	--
GO:0043231	intracellular membrane-bounded organelle	IDA	--

CASZ1 for ontologies About GeneDecksing

CASZ1 Antibody Products:

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	Novus Biologicals CASZ1 Antibodies
	Search for Antibodies for CASZ1 at Abcam
	Uscn Antibodies for CASZ1
	ThermoFisher Antibodies for CASZ1

Assay Products for CASZ1:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
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	GenScript Custom Assay Services for CASZ1
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for CASZ1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CASZ1 for domains About GeneDecksing

2 InterPro domains/families:

IPR015880 Znf_C2H2-like

IPR007087 Znf_C2H2

Graphical View of Domain Structure for InterPro Entry Q86V15

ProtoNet protein and cluster: Q86V15

UniProtKB/Swiss-Prot: CASZ1_HUMAN, Q86V15

Similarity: Contains 8 C2H2-type zinc fingers

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: CASZ1_HUMAN, Q86V15

Function: Probable transcription factor (By similarity)

miRNA Products:		OriGene 3'-UTR Clone (see all 2): CASZ1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CASZ1
		8/101 QIAGEN miScript miRNA Assays for microRNAs that regulate CASZ1 (see all 101):
		hsa-miR-15a hsa-miR-146a hsa-miR-371-5p hsa-miR-10b* hsa-miR-3150b-3p hsa-miR-3613-3p hsa-miR-376c hsa-miR-3148

		SwitchGear 3'UTR luciferase reporter plasmid: CASZ1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CASZ1 (see all 4) OriGene shRNA RFP: CASZ1 OriGene siRNA: CASZ1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CASZ1

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for CASZ1

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CASZ1 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CASZ1 (see all 3) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): CASZ1 (NM_017766)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for CASZ1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CASZ1

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for CASZ1
		Search LifeMap BioReagents cell lines for CASZ1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CASZ1

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	IEA	--
GO:0008270	zinc ion binding	IEA	--

CASZ1 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for CASZ1

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006351	transcription, DNA-dependent	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	IEA	--

CASZ1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CASZ1
Search CenterWatch for drugs/clinical trials and news about CASZ1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CASZ1 gene (3 alternative transcripts):

NM_001079843.2 NM_017766.4 NM_001039183.2

Unigene Cluster for CASZ1:

Castor zinc finger 1

Hs.439894 [show with all ESTs]

Unigene Representative Sequence: NM_001079843

9 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000377022(uc001aro.3) ENST00000478524 ENST00000447850 ENST00000344008(uc001arp.1)

ENST00000490176 ENST00000496432(uc009vmx.2) ENST00000492173(uc001arq.1)

ENST00000478728 ENST00000472814

miRNA Products:		OriGene 3'-UTR Clone (see all 2): CASZ1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CASZ1
		8/101 QIAGEN miScript miRNA Assays for microRNAs that regulate CASZ1 (see all 101):
		hsa-miR-15a hsa-miR-146a hsa-miR-371-5p hsa-miR-10b* hsa-miR-3150b-3p hsa-miR-3613-3p hsa-miR-376c hsa-miR-3148

		SwitchGear 3'UTR luciferase reporter plasmid: CASZ1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CASZ1 (see all 4) OriGene shRNA RFP: CASZ1 OriGene siRNA: CASZ1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CASZ1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CASZ1 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CASZ1 (see all 3) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): CASZ1 (NM_017766)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for CASZ1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CASZ1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CASZ1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat CASZ1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CASZ1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CASZ1

Additional cDNA sequence:

AK000328.1 AK092289.1 AK130996.1 AK225324.1 AK293839.1 AK311700.1 BC004410.1 BC051883.2

DQ217660.1 DQ372703.1

9 DOTS entries:

DT.306457 DT.40218363 DT.428007 DT.97822597 DT.99926552 DT.121333867 DT.97775768 DT.100806496

DT.91638235

24/64 AceView cDNA sequences (see all 64):

BQ073749 AW129465 AI935220 AI025065 BC004410 AI446176 AA410866 AW516662

AI671758 BE676352 AW079610 BC051883 BM800348 BM978297 NM_017766 BM795595

BE466522 AK000328 BQ446531 BQ423979 BM048706 BQ188241 BQ188091 AK092289

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CASZ1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACTGATGCAA

About this image

CASZ1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Limb

Forelimb Myotome

Limb Muscle Progenitor Cells

Skeletal Muscle

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 3 LifeMap Cells

Name

Category

PureStem™ progenitor T42 (Embryonic Progenitor Cell)

PureStem™ progenitor U31 (Embryonic Progenitor Cell)

Pancreatic endoderm/endocrine precursor-like cells (A scalable, suspensi...)

See CASZ1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CASZ1

SOURCE GeneReport for Unigene cluster: Hs.439894

UniProtKB/Swiss-Prot: CASZ1_HUMAN, Q86V15

Tissue specificity: Expressed in heart, lung, skeletal muscle, pancreas, testis, small intestine, and stomach, but it

is not detectable in the adult brain

SABiosciences Custom PCR Arrays for CASZ1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CASZ1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat CASZ1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CASZ1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CASZ1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CASZ1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for CASZ1 gene from 5/15 species (see all 15) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Casz1^{1 , 5}	castor homolog 1, zinc finger (Drosophila)⁵ castor zinc finger 1¹	88.49(n)¹ 91.57(a)¹		4 (78.87 cM)⁵ 69743¹ NM_001159344.1¹ NP_001152816.1¹ 148804429⁵
chicken (Gallus gallus)	Aves	CASZ1¹	castor zinc finger 1	76.67(n) 78.24(a)		419452 XM_417611.3 XP_417611.3
lizard (Anolis carolinensis)	Reptilia	CASZ1⁶	--	72(a)	1 ↔ 1	GL343565.1(13324-100443)
zebrafish (Danio rerio)	Actinopterygii	wufc21h10²	wufc21h10	83.82(n)		324216 57047493
fruit fly (Drosophila melanogaster)	Insecta	cas⁶ CG7512⁶	--	24(a) 23(a)	many → 1 many → 1	3R(1538664-1543022) 3L(11506805-11512004)

ENSEMBL Gene Tree for CASZ1 (if available)
TreeFam Gene Tree for CASZ1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for CASZ1 gene

CASZ1 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for CASZ1
PGOHUM00000247091

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data				Transcription Related Data				Allele Frequencies
			--	--	--		--	--
rs148190470^1,2	--	10696179(+)	`CCACCC/TTGTGC`	1	--	ds500¹		0	--	--	--	--
rs141174006^1,2	--	10696210(+)	`GCATCC/TGGATT`	1	--	ds500¹		0	--	--	--	--
rs72641441^1,2	--	10696229(+)	`GTACGC/TGCCGT`	1	--	ds500¹		0	--	--	--	--
rs150363881^1,2	--	10696397(+)	`CCTTGC/GTGTCA`	1	--	ds500¹		0	--	--	--	--
rs138092655^1,2	--	10696415(+)	`CTGCCC/GAAAGA`	1	--	ds500¹		0	--	--	--	--
rs201550899^1,2	--	10696647(+)	`AAAAG-/ATATAAC`	1	--	ds500¹		0	--	--	--	--
rs186259143^1,2	--	10696659(+)	`TGATAC/GATTTT`	1	--	ds500¹		0	--	--	--	--
rs190708048^1,2	--	10696942(+)	`ATATAC/TACACA`	1	--	ut3¹		0	--	--	--	--
rs181999733^1,2	--	10697008(+)	`AAAACA/GTTAAA`	1	--	ut3¹		0	--	--	--	--
rs142525076^1,2	--	10697047(+)	`CCCCAC/TAGAAA`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for CASZ1 (10696661 - 10856707 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 10 variations for CASZ1
7 CNVs: 3282 30368 4205 1314 53188 9872 1536
3 Indels: 84047 74331 84046

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CASZ1

DNA2.0 Custom Variant and Variant Library Synthesis for CASZ1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CASZ1 for disorders           About GeneDecksing

OMIM gene information: 609895    OMIM disorders: --

6 diseases for CASZ1:    About MalaCards

childhood leukemia lymphoblastic leukemia migraine leukemia

hypertension neuroblastoma

Human Genome Epidemiology (HuGE) Navigator: CASZ1 (4 documents)

Export disorders for CASZ1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for CASZ1 gene, integrated from 9 sources (see all 22):
(articles sorted by number of sources associating them with CASZ1)

Utopia: connect your pdf to the dynamic
world of online information

Molecular cloning and characterization of human Castor, a novel human gene upregulated during cell differentiation. (PubMed id 16631614)^{1, 2, 3} Liu Z.... Thiele C.J. (2006)
CASZ1, a candidate tumor-suppressor gene, suppresses neuroblastoma tumor growth through reprogramming gene expression. (PubMed id 21252912)^{1, 3} Liu Z....Thiele C.J. (2011)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{1, 2} Gregory S.G.... Bentley D.R. (2006)
Identification and characterization of survival-related gene, a novel cell survival gene controlling apoptosis and tumorigenesis. (PubMed id 16322216)^{1, 2} Yuan Z.-R.... Shi Y. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Loss of gene function as a consequence of human papill omavirus DNA integration. (PubMed id 22262398)¹ Schmitz M....Durst M. (2012)
Characterization of critical domains within the tumor suppressor CASZ1 required for transcriptional regulation and growth suppression. (PubMed id 22331471)¹ Virden R.A....Liu Z. (2012)
EZH2 Mediates epigenetic silencing of neuroblastoma su ppressor genes CASZ1, CLU, RUNX3, and NGFR. (PubMed id 22068036)¹ Wang C....Thiele C.J. (2012)
CASZ1b, the short isoform of CASZ1 gene, coexpresses with CASZ1a during neurogenesis and suppresses neuroblastoma cell growth. (PubMed id 21490919)¹ Liu Z....Thiele C.J. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 54897	HGNC: 26002	AceView: FLJ20321	Ensembl:ENSG00000130940	euGenes: HUgn54897
ECgene: CASZ1	H-InvDB: CASZ1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for CASZ1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for CASZ1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for CASZ1 gene:
Search GeneIP for patents involving CASZ1

GeneCards and IP:
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GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
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castor zinc finger 1

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CASZ1 Gene

castor zinc finger 1

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