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Aliases for CASP16P Gene

Aliases for CASP16P Gene

  • Caspase 16, Pseudogene 2 3 5
  • Caspase 16, Apoptosis-Related Cysteine Peptidase (Putative) 2 3
  • Caspase 16, Apoptosis-Related Cysteine Peptidase Pseudogene 3
  • Putative Caspase-14-Like Pseudogene 3
  • CASP16 3

External Ids for CASP16P Gene

Previous HGNC Symbols for CASP16P Gene

  • CASP16

Previous GeneCards Identifiers for CASP16P Gene

  • GC16P003175
  • GC16P003262
  • GC16P003303
  • GC16P003338

Summaries for CASP16P Gene

GeneCards Summary for CASP16P Gene

CASP16P (Caspase 16, Pseudogene) is a Pseudogene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CASP16P Gene

Genomics for CASP16P Gene

Regulatory Elements for CASP16P Gene

Enhancers for CASP16P Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16G003190 1.2 FANTOM5 ENCODE 6.7 +47.1 47091 0.8 ATF1 ARID4B SIN3A ZNF2 GTF3C2 FOS ZHX2 ZNF491 ZNF623 ZNF579 ZNF205 ZNF213-AS1 THOC6 LOC105371055 CREBBP RNPS1 ERVK13-1 ZNF263 PDPK2P MTCO1P28
GH16G003142 1.1 ENCODE dbSUPER 0.7 -0.3 -256 3.1 HDAC1 TBP PKNOX1 NFIB AGO1 SREBF2 ZNF48 YY1 ZNF335 TCF12 ZNF205 ZNF213-AS1 MMP25 CASP16P
GH16G003133 1.4 ENCODE dbSUPER 0.4 -9.1 -9141 2.6 PKNOX1 FOXA2 CREB3L1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 ZNF213-AS1 TIGD7 CLUAP1 MTCO1P28 ZNF174 MTND1P8 ZNF205 MTRNR2L4 ERVK13-1 CASP16P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CASP16P on UCSC Golden Path with GeneCards custom track

Genomic Location for CASP16P Gene

Chromosome:
16
Start:
3,144,219 bp from pter
End:
3,149,963 bp from pter
Size:
5,745 bases
Orientation:
Plus strand

Genomic View for CASP16P Gene

Genes around CASP16P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CASP16P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CASP16P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CASP16P Gene

Proteins for CASP16P Gene

Post-translational modifications for CASP16P Gene

No Post-translational modifications

No data available for DME Specific Peptides for CASP16P Gene

Domains & Families for CASP16P Gene

Gene Families for CASP16P Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CASP16P: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CASP16P Gene

Function for CASP16P Gene

Phenotypes for CASP16P Gene

GenomeRNAi human phenotypes for CASP16P:
genes like me logo Genes that share phenotypes with CASP16P: view

Animal Model Products

miRNA for CASP16P Gene

miRTarBase miRNAs that target CASP16P

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CASP16P Gene

Localization for CASP16P Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CASP16P gene
Compartment Confidence
extracellular 3
cytosol 3
mitochondrion 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CASP16P Gene

Pathways & Interactions for CASP16P Gene

SuperPathways for CASP16P Gene

No Data Available

Interacting Proteins for CASP16P Gene

Gene Ontology (GO) - Biological Process for CASP16P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CASP16P Gene

Drugs & Compounds for CASP16P Gene

No Compound Related Data Available

Transcripts for CASP16P Gene

mRNA/cDNA for CASP16P Gene

(2) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CASP16P Gene

No ASD Table

Relevant External Links for CASP16P Gene

GeneLoc Exon Structure for
CASP16P
ECgene alternative splicing isoforms for
CASP16P

Expression for CASP16P Gene

NURSA nuclear receptor signaling pathways regulating expression of CASP16P Gene:

CASP16P
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CASP16P Gene

Orthologs for CASP16P Gene

This gene was present in the common ancestor of animals.

Orthologs for CASP16P Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CASP16 34 35
  • 98.89 (n)
dog
(Canis familiaris)
Mammalia CASP16 34 35
  • 80.6 (n)
cow
(Bos Taurus)
Mammalia LOC788915 34
  • 79.2 (n)
CASP16 35
  • 44 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC680728 34
  • 74.95 (n)
mouse
(Mus musculus)
Mammalia Casp16 34 35
  • 71.67 (n)
Casp16-ps 16
oppossum
(Monodelphis domestica)
Mammalia CASP16 35
  • 22 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CASP16 35
  • 20 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 15 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii CU467905.1 35
  • 12 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta Nc 35
  • 8 (a)
ManyToMany
Dredd 35
  • 5 (a)
ManyToMany
Species where no ortholog for CASP16P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CASP16P Gene

ENSEMBL:
Gene Tree for CASP16P (if available)
TreeFam:
Gene Tree for CASP16P (if available)

Paralogs for CASP16P Gene

No data available for Paralogs for CASP16P Gene

Variants for CASP16P Gene

Sequence variations from dbSNP and Humsavar for CASP16P Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000110809 -- 3,143,674(+) GTGGC(A/G)GTGGC upstream-variant-2KB
rs1000773259 -- 3,143,024(+) GAGCA(C/T)CGTCG intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1001181132 -- 3,150,404(+) GGGGG(A/G)AAGCG downstream-variant-500B
rs1001605999 -- 3,142,989(+) TCCCC(C/T)TGTGT intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1001669314 -- 3,144,744(+) CCAGC(C/G)TCCCT nc-transcript-variant

Variation tolerance for CASP16P Gene

Gene Damage Index Score: 1.67; 31.93% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CASP16P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CASP16P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CASP16P Gene

Disorders for CASP16P Gene

Relevant External Links for CASP16P

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CASP16P
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CASP16P

No disorders were found for CASP16P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CASP16P Gene

Publications for CASP16P Gene

  1. Identification of novel mammalian caspases reveals an important role of gene loss in shaping the human caspase repertoire. (PMID: 18281271) Eckhart L. … Tschachler E. (Mol. Biol. Evol. 2008) 2 3 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 64
  4. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 3 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for CASP16P Gene

Sources for CASP16P Gene

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