CASP14 Gene
protein-coding GIFtS: 56
GCID: GC19P015160
|
|
caspase 14, apoptosis-related cysteine peptidase(Previous names: caspase 14, apoptosis-related cysteine protease )
| |
Aliases
for CASP14 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Caspase 14, Apoptosis-Related Cysteine Peptidase1 2 | | MICE1 | | Caspase 14, Apoptosis-Related Cysteine Protease1 2 | | Apoptosis-Related Cysteine Protease2 | | CASP-142 3 | | Caspase-141 | | MGC1190781 | | EC 3.4.22.-3 | | MGC1190791 | | |
Export aliases for CASP14 gene to outside databasesPrevious GC identifers: GC19P015542 GC19P015008 GC19P015024 GC19P014730 |
Summaries
for CASP14 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CASP14:
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspasesplays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergoproteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to formthe active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, andby anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of thiscaspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skinbarrier. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: CASPE_HUMAN, P31944Function: Believed to be a non-apoptotic caspase which is involved in epidermal differentiation. Seems to play a rolein keratinocyte differentiation and cornification. Probably regulates maturation of the epidermis by proteolyticallyprocessing filaggrin (By similarity)
 summary
for CASP14: Caspases (short for 'cysteinyl aspartate proteases') are involved in the signal transduction pathways of
apoptosis, necrosis and inflammation. These enzymes can be divided into two major classes - initiators and
effectors. The initiator isoforms (caspases-1,-4,-5,-8,-9,-10,-11,-12) are activated by, and interact with,
upstream adaptor molecules through protein-protein interaction domains known as CARD and DED. Effector
caspases (-3,-6,-7) are responsible for cleaving downstream substrates and are sometimes referred to as the
executioner caspases. More than 400 caspase substrates have so far been identified (see The Caspase
Substrate Database). Initiator caspases, such as caspase 8, may be directly activated by death receptors
such as FasR. Caspases can also be found intracellularly as part of large multiprotein complexes. For
example, caspase 9 is recruited to the apoptosome formed during apoptosis, whilst caspases-1 and 5 can form
part of the inflammasome, a key part of cytokine processing during inflammation. Caspases are regulated by
inhibitors of apoptosis and by dominant negative isoforms. They have been implicated in the pathogenesis of
many disorders including stroke, Alzheimer's disease, myocardial infarction, cancer, and inflammatory
disease.
Gene Wiki entry for CASP14 (Caspase 14)
|
Genomic Views
for CASP14 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011295.11
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CASP14 gene promoter:
AhR Elk-1 p53 AML1a FOXO3 HNF-3beta FOXO3b C/EBPalpha Arnt FOXO3a
Other transcription factors
Search SABiosciences Chromatin IP Primers for CASP14
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CASP14 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.1 Ensembl cytogenetic band: 19p13.12 HGNC cytogenetic band: 19p13.1CASP14 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P015160: view genomic region
(about GC identifiers)
Start:
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15,160,291 bp from pter |
End:
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15,166,900 bp from pter |
Size:
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6,610 bases |
Orientation:
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plus strand |
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Proteins
for CASP14 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CASPE_HUMAN, P31944 (See
protein sequence)Recommended Name: Caspase-14 precursor Size: 242 amino acids; 27680 Da
Subunit: Complex of unprocessed caspase-14 and processed 19 kDa (p19) and 10 kDa (p10) subunits
Subcellular location: Cytoplasm. Nucleus
Secondary accessions: O95823 Q3SYC9Explore the universe of human proteins at neXtProt for CASP14: NX_P31944
CASP14 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_036246.1
ENSEMBL proteins: ENSP00000393417 ENSP00000221740
Human Recombinant Protein Products for CASP14:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
CASP14 for ontologies About GeneDecksing
CASP14 Antibody Products:
Assay Products for CASP14: |
Protein
Domains /
Families
for CASP14 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CASP14 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry P31944ProtoNet protein and cluster: P31944 1 Blocks protein family: IPB002398 Interleukin-1B converting enzyme signature
UniProtKB/Swiss-Prot: CASPE_HUMAN, P31944Similarity: Belongs to the peptidase C14A family |
Function
for CASP14 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: CASPE_HUMAN, P31944Function: Believed to be a non-apoptotic caspase which is involved in epidermal differentiation. Seems to play a rolein keratinocyte differentiation and cornification. Probably regulates maturation of the epidermis by proteolyticallyprocessing filaggrin (By similarity)Induction: In undifferentiated keratinocytes under postconfluency growth conditions (in vitro) Genatlas biochemistry entry for CASP14:caspase 14,cysteine containing aspartate-specific protease,stored in the mitochondrial intermembrane space and releasedinto cytosol after appropriate apoptotic stimuli,promoting apoptosis,homolog to murine CASP14 expressed in embryo andin adult skin
Enzyme Number (IUBMB): EC 3.4.22.-1
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004197 | cysteine-type endopeptidase activity |
IEA | -- |
CASP14 for ontologies About GeneDecksing
Phenotypes:
2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Casp14):
CASP14 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Casp14tm1Wdec for CASP14
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CASP14 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CASP14
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector: CASP14 (NM_012114) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CASP14 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CASP14 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CASP14 |
|
Pathways & Interactions
for CASP14 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Apoptosis and Autophagy | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Cell Signaling Technology (CST) Pathway for CASP14
CASP14 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CASP14
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/17 Interacting proteins for CASP14 (P319443 ENSP000002217404) via UniProtKB, MINT, STRING, and/or I2D (see all 17)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
CASP14 for ontologies About GeneDecksing
|
Drugs & Compounds
for CASP14 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
CASP14 for compounds About GeneDecksing
Compounds for CASP14 available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| Ac-LEHD-AFC | Fluorogenic caspase substrate | [210345-03-2] | | Z-VAD-FMK | Cell-permeable, irreversible caspase inhibitor | -- |
6 Novoseek chemical compound relationships for CASP14 gene About this table
Search CenterWatch for drugs/clinical trials and news about CASP14 / CASPE
|
Transcripts
for CASP14 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CASP14 gene: NM_012114.2 Unigene Cluster for CASP14: Caspase 14, apoptosis-related cysteine peptidase Hs.466057 [show with all ESTs]Unigene Representative Sequence: EU5027482 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000427043(uc010dzv.2) ENST00000221740
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CASP14 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CASP14
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CASP14 (NM_012114) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CASP14 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CASP14 |
Additional cDNA sequence: AF097874.1 AK313992.1 BC069541.1 BC103868.1 BC103869.1 EU262664.1 EU502748.1 5 DOTS entries: DT.91716894 DT.91756482 DT.91716891 DT.121486669 DT.91730497 16 AceView cDNA sequences: AF097874 BC069541 NM_012114 BF843203 BF380910 BF739066 BE940739 BF093917 BF914944 AW796525 BF737240 AW796661 BE939716 BQ300908 BF916315 BF380585
GeneLoc Exon Structure
|
Expression
for CASP14 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CASP14 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AATTCACTCT
About this image
See CASP14 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CASP14
SOURCE GeneReport for Unigene cluster: Hs.466057
UniProtKB/Swiss-Prot: CASPE_HUMAN, P31944Tissue specificity: Expressed in keratinocytes of adult skin suprabasal layers (from spinous layers to the stratumgranulosum and stratum corneum) (at protein level). Expressed in keratinocytes of hair shaft and sebaceous glands (atprotein level). In psoriatic skin only expressed at very low levels
SABiosciences Expression via Pathway-Focused PCR Arrays including CASP14:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CASP14
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CASP14 |
Orthologs
for CASP14 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CASP14 gene from 4/15 species (see all 15) About this table
ENSEMBL Gene Tree for CASP14 (if available)
TreeFam Gene Tree for CASP14 (if available) |
Paralogs
for CASP14 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CASP14 gene
- CASP162 CASP62 CASP82 CASP122 CASP92 CASP72 CASP32 CASP22
- CASP12 CASP52 CASP102 CASP42
3 SIMAP similar genes for CASP14 using alignment to 3 protein entries: CASPE_HUMAN (see all proteins):DKFZp586A181 CASP16 CASP2
CASP14 for paralogs About GeneDecksing
|
Genomic Variants
for CASP14 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CASP14 (15160291 - 15166900 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for CASP14
5 CNVs: 89128 4068 78111 89125 89126 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CASP14 |
|
Disorders
/ Diseases
for CASP14 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CASP14 for disorders About GeneDecksing
OMIM gene information: 605848
OMIM disorders: --
20/28  diseases for CASP14 (see all 28): About MalaCardsmiddle ear cholesteatoma eczema herpeticum plasma cell neoplasm non-hodgkin lymphoma
gastrointestinal stromal tumor hodgkin's lymphoma male infertility cholesteatoma
ulcerative colitis glanders ptosis eczema
candidiasis keloids infertility psoriasis
hepatitis b skin cancer breast cancer lung adenocarcinoma
7 Novoseek disease relationships for CASP14 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| psoriasis |
14 |
3 |
15619438 (1), 15556625 (1) |
| carcinoma squamous cell |
7.65 |
4 |
15537824 (1), 16061209 (1), 17366476 (1) |
| breast cancer |
0.0455 |
1 |
16061209 (1) |
| necrosis |
0 |
1 |
16907856 (1) |
| inflammation |
0 |
2 |
17558860 (1), 16061862 (1) |
| tumors |
0 |
10 |
16061862 (2), 19846913 (2), 15537824 (1), 16061209 (1) |
| cancer |
0 |
14 |
17558860 (2), 16061862 (2), 19846913 (1), 17436577 (1) |
Human Genome Epidemiology (HuGE) Navigator: CASP14 (7 documents)
Export disorders for CASP14 gene to outside databases
|
Publications
for CASP14 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CASP14 gene, integrated from 9 sources (see all 77):
(articles sorted by number of sources associating them with CASP14) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Expression and transcriptional regulation of caspase-14 in simple and complex epithelia. (PubMed id 12181750)1, 2, 9 Pistritto G.... Alnemri E.S. (2002)
- Processing of native caspase-14 occurs at an atypical cleavage site in normal epidermal differentiation. (PubMed id 12200134)1, 2, 9 Chien A.J.... Kuechle M.K. (2002)
- Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing. (PubMed id 11175259)1, 2, 9 Lippens S.... Declercq W. (2000)
- Caspase-14: analysis of gene structure and mRNA expression during keratinocyte differentiation. (PubMed id 11062009)1, 2, 9 Eckhart L.... Tschachler E. (2000)
- Identification of a new caspase homologue: caspase-14. (PubMed id 10203698)1, 3, 9 Van de Craen M....Vandenabeele P. (1998)
- Caspase-14 is a novel developmentally regulated protease. (PubMed id 9792675)1, 3, 9 Hu S....Dixit V.M. (1998)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes. (PubMed id 1286667)1, 2 Rasmussen H.H....Vandekerckhove J. (1992)
- Tumor-associated alterations in caspase-14 expression in epithelial malignancies. (PubMed id 16061862)1, 9 Krajewska M....Krajewski S. (2005)
- Vitamin D3 induces caspase-14 expression in psoriatic lesions and enhances caspase-14 processing in organotypic skin cultures. (PubMed id 15331408)1, 9 Lippens S....Declercq W. (2004)
|
External Searches for CASP14 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CASP14 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CASP14 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CASP14 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for CASP14 gene:
Search GeneIP for patents involving CASP14
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CASP14 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
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