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CASKIN2 Gene

protein-coding   GIFtS: 50
GCID: GC17M073496

CASK Interacting Protein 2

  Search for CASKIN2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
CASK Interacting Protein 21 2
KIAA11393 5
ANKS5B2
caskin-22
CASK-Interacting Protein 23

External Ids:    HGNC: 182001   Entrez Gene: 575132   Ensembl: ENSG000001773037   OMIM: 6121855   UniProtKB: Q8WXE03   

Export aliases for CASKIN2 gene to outside databases

Previous GC identifers: GC00U990821 GC17M076522 GC17M073960 GC17M074093 GC17M071007 GC17M068919


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CASKIN2 Gene:
This gene encodes a large protein that contains six ankyrin repeats, as well as a Src homology 3 (SH3) domain and
two sterile alpha motif (SAM) domains, which may be involved in protein-protein interactions. The C-terminal
portion of this protein is proline-rich and contains a conserved region. A related protein interacts with
calcium/calmodulin-dependent serine protein kinase (CASK). Alternative splicing results in multiple transcript
variants. (provided by RefSeq, Mar 2013)

GeneCards Summary for CASKIN2 Gene:
CASKIN2 (CASK interacting protein 2) is a protein-coding gene. An important paralog of this gene is CASKIN1.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NC_018928.2  NT_010783.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the CASKIN2 gene promoter:
         NF-1/L   Pax-6   HOXA5   HNF-4alpha2   Ik-1   C/EBPalpha   HNF-4alpha1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCASKIN2 promoter sequence
   Search Chromatin IP Primers for CASKIN2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CASKIN2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.1   Ensembl cytogenetic band:  17q25.1   HGNC cytogenetic band: 17q25.2

CASKIN2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CASKIN2 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M073496:  view genomic region     (about GC identifiers)

Start:
73,496,342 bp from pter      End:
73,511,664 bp from pter
Size:
15,323 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CSKI2_HUMAN, Q8WXE0 (See protein sequence)
Recommended Name: Caskin-2  
Size: 1202 amino acids; 126783 Da
Subunit: May not bind CASK
1 PDB 3D structure from and Proteopedia for CASKIN2:
2KE9 (3D)    
Secondary accessions: B4DTT3 B7Z9H1 Q7LG69 Q9ULT1
Alternative splicing: 2 isoforms:  Q8WXE0-1   Q8WXE0-2   

Explore the universe of human proteins at neXtProt for CASKIN2: NX_Q8WXE0

Explore proteomics data for CASKIN2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CASKIN2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001136115.1  NP_065804.2  

    ENSEMBL proteins: 
     ENSP00000325355   ENSP00000406963   ENSP00000464300   ENSP00000463211  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ANKRD: Ankyrin repeat domain containing
    SAMD: Sterile alpha motif (SAM) domain containing

    Selected InterPro protein domains (see all 8):
     IPR027001 Caskin/Ankyrin_rpt_con_pro
     IPR021129 SAM_type1
     IPR001452 SH3_domain
     IPR002110 Ankyrin_rpt
     IPR011511 SH3_2

    Graphical View of Domain Structure for InterPro Entry Q8WXE0

    ProtoNet protein and cluster: Q8WXE0

    4 Blocks protein domains:
    IPB001452 SH3 domain signature
    IPB001660 Sterile alpha motif SAM
    IPB002110 Ankyrin repeat signature
    IPB011511 Variant SH3


    UniProtKB/Swiss-Prot: CSKI2_HUMAN, Q8WXE0
    Similarity: Contains 6 ANK repeats
    Similarity: Contains 2 SAM (sterile alpha motif) domains
    Similarity: Contains 1 SH3 domain


    CASKIN2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005515protein binding ----
         
    CASKIN2 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Caskin2 (no phenotypes)

    CASKIN2 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CASKIN2
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    miRNA
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    hsa-mir-222-3p (MIRT046713), hsa-mir-335-5p (MIRT018329)

    Block miRNA regulation of human, mouse, rat CASKIN2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CASKIN2 (see all 14):
    hsa-miR-569 hsa-miR-34b* hsa-miR-206 hsa-miR-3673 hsa-miR-3152-3p hsa-miR-1266 hsa-miR-586 hsa-miR-1
    SwitchGear 3'UTR luciferase reporter plasmidCASKIN2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CASKIN2

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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CASKIN2

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CSKI2_HUMAN, Q8WXE0: Cytoplasm (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus3

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ISS12040031

    CASKIN2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CASKIN2
    Interactions:

        Search GeneGlobe Interaction Network for CASKIN2

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    Selected Interacting proteins for CASKIN2 (Q8WXE02, 3 ENSP000003253554) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PACSIN1Q9BY113I2D: score=2 
    TGFBR1P368973I2D: score=2 
    SH3KBP1ENSP000003809214STRING: ENSP00000380921
    FAM49AENSP000003477444STRING: ENSP00000347744
    --Q777G92MINT-6769915
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    CASKIN2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CASKIN2 (CSKI2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CASKIN2 gene (2 alternative transcripts): 
    NM_001142643.2  NM_020753.4  

    Unigene Cluster for CASKIN2:

    CASK interacting protein 2
    Hs.274408  [show with all ESTs]
    Unigene Representative Sequence: NM_020753
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000321617(uc010wsc.2 uc002joc.3) ENST00000433559 ENST00000580021
    ENST00000581870(uc002jod.3) ENST00000583258 ENST00000583246 ENST00000580075

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate CASKIN2 (see all 14):
    hsa-miR-569 hsa-miR-34b* hsa-miR-206 hsa-miR-3673 hsa-miR-3152-3p hsa-miR-1266 hsa-miR-586 hsa-miR-1
    SwitchGear 3'UTR luciferase reporter plasmidCASKIN2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CASKIN2
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    GenScript: all cDNA clones in your preferred vector (see all 2): CASKIN2 (NM_001142643)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CASKIN2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CASKIN2
    Primer
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    OriGene qPCR primer pairs and template standards for CASKIN2
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CASKIN2
      QuantiTect SYBR Green Assays in human, mouse, rat CASKIN2
      QuantiFast Probe-based Assays in human, mouse, rat CASKIN2

    Additional mRNA sequence: 

    AB032965.1 AF451976.1 AK025262.1 AK300354.1 AK315936.1 BC032359.1 BC066643.1 

    4 DOTS entries:

    DT.97814321  DT.100818985  DT.91765253  DT.100038258 

    Selected AceView cDNA sequences (see all 114):

    AA586863 BM717363 BU624833 AA300357 BC066643 BQ229696 BG913088 AB032965 
    AI637753 BM716852 AA362564 BI966211 BE294747 BI011157 CK904068 NM_020753 
    BF530041 AA640137 AI479679 BG392360 BI966142 CB216246 BX117405 AW005347 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CASKIN2 (see all 12)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b ^ 11a · 11b · 11c ^ 12a · 12b · 12c ^ 13 ^ 14 ^ 15 ^ 16a ·
    SP1:                                                                                                                                                            
    SP2:                                                                                -                                                                           
    SP3:                                                                                -                                                                           
    SP4:                                                                                                                                                            
    SP5:                                                                                -                                                                           

    ExUns: 16b ^ 17a · 17b ^ 18 ^ 19 ^ 20a · 20b ^ 21 ^ 22 ^ 23 ^ 24 ^ 25
    SP1:                                                                        
    SP2:                                                                        
    SP3:                                                                        
    SP4:                                                                        
    SP5:                                                                        


    ECgene alternative splicing isoforms for CASKIN2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CASKIN2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAAATACACA
    CASKIN2 Expression
    About this image

    CASKIN2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CASKIN2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.274408
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CASKIN2 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Caskin21 , 5 CASK-interacting protein 21, 5 85.76(n)1
    90.58(a)1
      11 (80.91 cM)5
    1407211  NM_080643.21  NP_542374.21 
     1157991835 
    chicken
    (Gallus gallus)
    Aves CASKIN21 CASK interacting protein 2 66.52(n)
    65.78(a)
      422125  XM_420128.4  XP_420128.4 
    lizard
    (Anolis carolinensis)
    Reptilia CASKIN26
    CASK interacting protein 2
    60(a)
    1 ↔ 1
    2(114303331-114402517)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.22972 Xenopus laevis transcribed sequence with weak similarity more 75.07(n)    48023046 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.214602 Transcribed sequence with weak similarity to protein more 76.9(n)    57050370 
    worm
    (Caenorhabditis elegans)
    Secernentea C46H3.26
    Protein C46H3.2, isoform a
    22(a)
    many ↔ many
    X(1211759-1220029) WBGene00016725


    ENSEMBL Gene Tree for CASKIN2 (if available)
    TreeFam Gene Tree for CASKIN2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CASKIN2 gene
    CASKIN12  ANKS1A2  ANKS1B2  
    13 SIMAP similar genes for CASKIN2 using alignment to 3 protein entries:     CSKI2_HUMAN (see all proteins):
    OSBPL1A    ANKS1A    ANKRD12    KRIT1    ANKRD42    HACE1
    RAI14    ANKRD6    ANKRD44    CDKN2C    GABPB1    ANKRD65
    FEM1B

    CASKIN2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CASKIN2 (see all 606)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs349602421,2
    C--68930466(+) GGCAT-/CTTA  
            
    CTATG
    1 -- int10--------
    rs594310521,2
    C--68930468(+) CATCTTACT/-  
            
    ATGTT
    2 -- int1 us2k11Minor allele frequency- -:0.50NA 2
    rs359026451,2
    C--68931592(+) CAAGG-/CCCCAC 1 -- int11Minor allele frequency- C:0.00NA 2
    rs2015847791,2
    --68936672(+) GGGGTA/GAGGGA 1 -- us2k10--------
    rs353098261,2
    C--73509281(+) GCCTA-/C/CCTA
            
    GGTGG
    1 -- int10--------
    rs1410252991,2
    C--73509281(+) GGAGG-/CCTA  
            
    CCTAG
    1 -- int10--------
    rs1470509161,2
    --74579808(+) GCCGAC/TGCGTC 2 -- ds50010--------
    rs1917632791,2
    --74579842(+) GGCAGC/GGGGGT 2 -- ds50010--------
    rs1383940421,2
    --74579928(+) ATGGAA/GCAGGG 2 -- ds50010--------
    rs1847341491,2
    --74579989(+) CTGTCA/GGTCTT 2 -- ds50010--------

    HapMap Linkage Disequilibrium report for CASKIN2 (73496342 - 73511664 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for CASKIN2:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv516133CNV Loss19592680
    nsv470603CNV Loss18288195
    nsv908775CNV Loss21882294
    nsv908762CNV Loss21882294
    dgv3256n71CNV Loss21882294
    nsv833542CNV Loss17160897
    dgv3258n71CNV Loss21882294
    dgv3257n71CNV Loss21882294
    nsv908763CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612185    OMIM disorders: --


    CASKIN2 for disorders           About GeneDecksing


    Export disorders for CASKIN2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CASKIN2 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with CASKIN2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. CASK participates in alternative tripartite complexes in which Mint 1 competes for binding with Caskin 1, a novel CASK-binding protein. (PubMed id 12040031)1, 2, 3 Tabuchi K.... Suedhof T.C. (J. Neurosci. 2002)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PubMed id 10574461)1, 2 Hirosawa M.... Ohara O. (DNA Res. 1999)
    4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    5. Error tolerant NMR backbone resonance assignment and automated structure generation. (PubMed id 21328705)2 Alipanahi B.... Li M. (J. Bioinform. Comput. Biol. 2011)
    6. A human sterile alpha motif domain polymerizome. (PubMed id 21805519)1 Knight M.J....Bowie J.U. (Protein Sci. 2011)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    9. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)
    10. Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS. (PubMed id 19531213)1 Havrylov S....Redowicz M.J. (Proteome Sci 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57513 HGNC: 18200 AceView: CASKIN2 Ensembl:ENSG00000177303 euGenes: HUgn57513
    ECgene: CASKIN2 H-InvDB: CASKIN2

    (According to HUGE)
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    HUGE: KIAA1139

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CASKIN2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CASKIN2 gene:
    Search GeneIP for patents involving CASKIN2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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