Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



CASD1 Gene

protein-coding   GIFtS: 48
GCID: GC07P094139

CAS1 Domain Containing 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
CAS1 Domain Containing 11 2     O-acetyltransferase2
C7orf122 3 5     WUGSC:H_GS542D18.22
Chromosome 7 Open Reading Frame 121     CAS1 Domain-Containing Protein 12
NBLA041962     

External Ids:    HGNC: 160141   Entrez Gene: 649212   Ensembl: ENSG000001279957   OMIM: 6116865   UniProtKB: Q96PB13   

Export aliases for CASD1 gene to outside databases

Previous GC identifers: GC07P093977 GC07P088746


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for CASD1 Gene:
CASD1 (CAS1 domain containing 1) is a protein-coding gene. Diseases associated with CASD1 include myoclonus-dystonia, and brachydactyly-syndactyly syndrome.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000007.14  NT_007933.16  NC_018918.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for CASD1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): CASD1 promoter sequence
   Search Chromatin IP Primers for CASD1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CASD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q21.3   Ensembl cytogenetic band:  7q21.3   HGNC cytogenetic band: 7q22

CASD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CASD1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P094139:  view genomic region     (about GC identifiers)

Start:
94,138,531 bp from pter      End:
94,186,331 bp from pter
Size:
47,801 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 93,468,325-93,515,486     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: CASD1_HUMAN, Q96PB1 (See protein sequence)
Recommended Name: CAS1 domain-containing protein 1 precursor  
Size: 797 amino acids; 91680 Da
Sequence caution: Sequence=AAB69978.1; Type=Erroneous gene model prediction; Sequence=BAB15028.1; Type=Frameshift;
Positions=780; Sequence=BAB15163.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAB15163.1; Type=Frameshift; Positions=543;
Secondary accessions: B3KW13 O14574 Q3LIE2 Q6P4R4 Q9H6T9 Q9H770

Explore the universe of human proteins at neXtProt for CASD1: NX_Q96PB1

Explore proteomics data for CASD1 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn141, Asn175, Asn187, Asn241

  • See CASD1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_075051.4  
    ENSEMBL proteins: 
     ENSP00000396261   ENSP00000297273   ENSP00000389718   ENSP00000402708  

    CASD1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for CASD1
    OriGene Custom MassSpec
    OriGene Custom Protein Services for CASD1
    GenScript Custom Purified and Recombinant Proteins Services for CASD1
    Novus Biologicals CASD1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CASD1

    CASD1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for CASD1
    Novus Biologicals CASD1 Antibodies
    Abcam antibodies for CASD1
    Cloud-Clone Corp. Antibodies for CASD1
    Search ThermoFisher Antibodies for CASD1
    LSBio Antibodies in human, mouse, rat for CASD1

    CASD1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CASD1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CASD1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CASD1
    Cloud-Clone Corp. CLIAs for CASD1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    3 InterPro protein domains:
     IPR013763 Cyclin-like
     IPR026057 PC-Esterase
     IPR012419 Cas1_AcylTrans_dom

    Graphical View of Domain Structure for InterPro Entry Q96PB1

    ProtoNet protein and cluster: Q96PB1

    1 Blocks protein domain: IPB012419 Cas1p-like

    UniProtKB/Swiss-Prot: CASD1_HUMAN, Q96PB1
    Similarity: Belongs to the PC-esterase family. CASD1 subfamily


    CASD1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    CASD1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CASD1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CASD1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CASD1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CASD1

    miRNA
    Products:
        
    miRTarBase miRNAs that target CASD1:
    hsa-mir-140-5p (MIRT045824), hsa-mir-26b-5p (MIRT029837)

    Block miRNA regulation of human, mouse, rat CASD1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CASD1 (see all 51):
    hsa-miR-142-5p hsa-miR-607 hsa-miR-429 hsa-miR-300 hsa-miR-875-5p hsa-miR-25 hsa-miR-301a hsa-miR-519a
    SwitchGear 3'UTR luciferase reporter plasmidCASD1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CASD1
    Predesigned siRNA for gene silencing in human, mouse, rat CASD1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CASD1

    Clone
    Products:
         
    OriGene clones in human, mouse for CASD1 (see all 7)
    OriGene ORF clones in mouse, rat for CASD1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CASD1 (NM_022900)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CASD1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CASD1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for CASD1
    Browse ESI BIO Cell Lines and PureStem Progenitors for CASD1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CASD1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    CASD1_HUMAN, Q96PB1: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    cytosol2
    golgi apparatus2
    endoplasmic reticulum1
    nucleus1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    CASD1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CASD1
    Interactions:

        Search GeneGlobe Interaction Network for CASD1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for CASD1 (ENSP000002972734) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CRKENSP000003005744STRING: ENSP00000300574
    INPPL1ENSP000002982294STRING: ENSP00000298229
    PTPN12ENSP000002485944STRING: ENSP00000248594
    CDC42ENSP000003144584STRING: ENSP00000314458
    SRCENSP000003509414STRING: ENSP00000350941
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CASD1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for CASD1 gene: 
    NM_022900.4  

    Unigene Cluster for CASD1:

    CAS1 domain containing 1
    Hs.260041  [show with all ESTs]
    Unigene Representative Sequence: NM_022900
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000447923 ENST00000297273(uc003unh.2 uc003uni.4 uc003unj.4)
    ENST00000443644 ENST00000417387 ENST00000471944 ENST00000489196
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CASD1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CASD1 (see all 51):
    hsa-miR-142-5p hsa-miR-607 hsa-miR-429 hsa-miR-300 hsa-miR-875-5p hsa-miR-25 hsa-miR-301a hsa-miR-519a
    SwitchGear 3'UTR luciferase reporter plasmidCASD1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CASD1
    Predesigned siRNA for gene silencing in human, mouse, rat CASD1
    Clone
    Products:
         
    OriGene clones in human, mouse for CASD1 (see all 7)
    OriGene ORF clones in mouse, rat for CASD1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CASD1 (NM_022900)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CASD1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CASD1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CASD1
    OriGene qSTAR qPCR primer pairs in human, mouse for CASD1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CASD1
      QuantiTect SYBR Green Assays in human, mouse, rat CASD1
      QuantiFast Probe-based Assays in human, mouse, rat CASD1

    Additional mRNA sequence: 

    AB073397.1 AF355594.1 AF397424.2 AK024866.1 AK025532.1 AK123866.1 AK123895.1 AK314329.1 
    BC029543.1 BC050313.1 BC063284.1 

    17 DOTS entries:

    DT.205751  DT.100693239  DT.99950269  DT.100783186  DT.101983733  DT.100783185  DT.121064700  DT.204161 
    DT.432293  DT.97790038  DT.97826978  DT.121064720  DT.121064766  DT.40280556  DT.92382293  DT.97780783 
    DT.99962387 

    Selected AceView cDNA sequences (see all 48):

    AA906339 AI922551 BQ004398 AI351608 AL138212 AW299791 BM857436 AK123895 
    AI968151 CA445988 CD511599 BM676290 BX110691 BX498458 AA969799 CK824125 
    AV682705 BI760512 AI240002 BX094597 AI222215 AA325212 CB993920 AL712889 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CASD1 (see all 9)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c · 9d ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^
    SP1:                                      -     -                                                                                                               
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                      -     -                                                                                                               
    SP5:              -     -     -     -     -     -                                                                                                               

    ExUns: 19 ^ 20
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for CASD1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    CASD1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAAGTTGTTA
    CASD1 Expression
    About this image

    CASD1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CASD1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.260041
        Custom PCR Arrays for CASD1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for CASD1
    OriGene qSTAR qPCR primer pairs in human, mouse for CASD1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CASD1
    QuantiTect SYBR Green Assays in human, mouse, rat CASD1
    QuantiFast Probe-based Assays in human, mouse, rat CASD1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CASD1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CASD1 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Casd11 , 5 CAS1 domain containing 11, 5 89.78(n)1
    94.97(a)1
      6 (1.81 cM)5
    2138191  NM_145398.21  NP_663373.21 
     46008405 
    chicken
    (Gallus gallus)
    Aves CASD11 CAS1 domain containing 1 80.05(n)
    84.57(a)
      420565  XM_001235381.3  XP_001235382.2 
    lizard
    (Anolis carolinensis)
    Reptilia CASD16
    CAS1 domain containing 1
    70(a)
    1 ↔ 1
    6(22243228-22273616)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia casd11 CAS1 domain containing 1 69.99(n)
    72.8(a)
      100216199  NM_001142168.1  NP_001135640.1 
    zebrafish
    (Danio rerio)
    Actinopterygii casd11 CAS1 domain containing 1 67.69(n)
    71.92(a)
      692268  NM_001278180.1  NP_001265109.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG29381 CG2938 47.51(n)
    38.74(a)
      31347  NM_001272297.1  NP_001259226.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G344101 AT2G34410 48.18(n)
    36.39(a)
      818004  NM_001036401.2  NP_001031478.1 
    rice
    (Oryza sativa)
    Liliopsida Os01g06311001 Os01g0631100 49.67(n)
    36.45(a)
      4326670  NM_001050179.1  NP_001043644.1 


    ENSEMBL Gene Tree for CASD1 (if available)
    TreeFam Gene Tree for CASD1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for CASD1 gene
    1 SIMAP similar gene for CASD1 using alignment to 4 protein entries:     CASD1_HUMAN (see all proteins):
    CAS1

    CASD1 for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for CASD1
    PGOHUM00000260460 PGOHUM00000260501 PGOHUM00000236475


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for CASD1 (see all 874)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs593750401,2
    C--93473895(+) TTTTT-/T/TT  
            
    GATAC
    1 -- int12NA 4
    rs568641211,2
    C--93492647(+) TTTTT-/T/TTT 
            
    GAGAC
    1 -- int11NA 2
    rs1380355441,2
    --94137424(+) CATGCG/TGATCA 1 -- us2k10--------
    rs1495023711,2
    --94137529(+) ACCCAA/GTTCTT 1 -- us2k10--------
    rs1828879631,2
    --94137550(+) ATCAAC/TCTCTG 1 -- us2k10--------
    rs102687661,2
    C,F,A,H--94137554(+) ACCTCC/TGATCA 1 -- us2k125Minor allele frequency- T:0.36NS EA NA WA CSA 2347
    rs1887323641,2
    --94137842(+) ATGGCC/TAAATG 1 -- us2k10--------
    rs1926865341,2
    --94137932(+) AAGCAA/CTGTAA 1 -- us2k10--------
    rs1439599891,2
    --94138011(+) AGTAGA/GGATAA 1 -- us2k10--------
    rs624656721,2
    C--94138099(+) ATTGTC/TATAAG 1 -- us2k13Minor allele frequency- T:0.08CSA NA EA 242

    HapMap Linkage Disequilibrium report for CASD1 (94138531 - 94186331 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for CASD1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2422248CNV Duplication17116639

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CASD1
    DNA2.0 Custom Variant and Variant Library Synthesis for CASD1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 611686    OMIM disorders: --

    7 diseases for CASD1:    
    About MalaCards
    myoclonus-dystonia    brachydactyly-syndactyly syndrome    brachydactyly    syndactyly
    myoclonus    neuroblastoma    malaria

    1 disease from the University of Copenhagen DISEASES database for CASD1:
    brachydactyly-syndactyly syndrome

    CASD1 for disorders           About GeneDecksing


    Export disorders for CASD1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for CASD1 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with CASD1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. Mutations in the gene encoding epsilon-sarcoglycan cause myoclonus- dystonia syndrome. (PubMed id 11528394)1, 3 Zimprich A.... Gasser T. (Nat. Genet. 2001)
    3. Cas1p is a membrane protein necessary for the O-acetylation of the Cryptococcus neoformans capsular polysaccharide. (PubMed id 11703667)1, 3 Janbon G.... Dromer F. (Mol. Microbiol. 2001)
    4. The human Cas1 protein: a sialic acid-specific O-acetyltransferase? (PubMed id 20947662)1 Arming S....Vlasak R. (Glycobiology 2011)
    5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)2 Scherer S.W.... Tsui L.-C. (Science 2003)
    8. The DNA sequence of human chromosome 7. (PubMed id 12853948)2 Hillier L.W.... Wilson R.K. (Nature 2003)
    9. Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma. (PubMed id 12880961)2 Ohira M.... Nakagawara A. (Cancer Lett. 2003)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 64921 HGNC: 16014 AceView: CAS1 Ensembl:ENSG00000127995 euGenes: HUgn64921
    ECgene: CASD1 H-InvDB: CASD1

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for CASD1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for CASD1 gene:
    Search GeneIP for patents involving CASD1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for CASD1  
     OriGene qPCR primer pairs and template standards for CASD1   OriGene Protein Over-expression Lysate for CASD1  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for CASD1  
     OriGene qSTAR qPCR primer pairs in human, mouse for CASD1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for CASD1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CASD1   OriGene Custom Protein Services for CASD1  

     
     
     Block miRNA regulation of human, mouse, rat CASD1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CASD1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CASD1 Predesigned siRNA for gene silencing in human, mouse, rat CASD1
     QuantiFast Probe-based Assays in human, mouse, rat CASD1 QuantiTect SYBR Green Assays in human, mouse, rat CASD1
     Custom PCR Arrays for CASD1 Search Chromatin IP Primers for CASD1
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CASD1  Search GeneGlobe Interaction Network for CASD1
     Search Regulatory tfbs for CASD1
     GenScript Custom Purified and Recombinant Proteins Services for CASD1 GenScript cDNA clones with any tag delivered in your preferred vector for CASD1
     GenScript Custom Assay Services for CASD1 GenScript Custom overexpressing Cell Line Services for CASD1
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for CASD1
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     CASD1 antibodies
     CASD1 lysates
     Antibodies for CASD1
     See all of Abcam's Antibodies, Kits and Proteins for CASD1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for CASD1
     Antibodies for CASD1
     ELISAs for CASD1
     CLIAs for CASD1



     Browse ESI BIO Cell Lines and PureStem Progenitors for CASD1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CASD1
     SwitchGear 3'UTR luciferase reporter plasmids for CASD1
     SwitchGear Promoter luciferase reporter plasmids for CASD1
     Search ThermoFisher Antibodies for CASD1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CASD1
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CASD1
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CASD1
     LSBio Antibodies in human, mouse, rat for CASD1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      CASD1 gene at Home site.
    Version: 3.12.142 28 July 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4