Free for academic non-profit institutions. Other users need a Commercial license

Aliases for CASC8 Gene

Subcategory (RNA class) for CASC8 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for CASC8 Gene

  • Cancer Susceptibility Candidate 8 (Non-Protein Coding) 2 3 5
  • Long Intergenic Non-Protein Coding RNA 860 2 3
  • LINC00860 3
  • CARLo-1 3

External Ids for CASC8 Gene

Previous GeneCards Identifiers for CASC8 Gene

  • GC08M128304

Summaries for CASC8 Gene

GeneCards Summary for CASC8 Gene

CASC8 (Cancer Susceptibility Candidate 8 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CASC8 Gene

Genomics for CASC8 Gene

Regulatory Elements for CASC8 Gene

Enhancers for CASC8 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CASC8 on UCSC Golden Path with GeneCards custom track

Genomic Location for CASC8 Gene

Chromosome:
8
Start:
127,289,676 bp from pter
End:
127,482,139 bp from pter
Size:
192,464 bases
Orientation:
Minus strand

Genomic View for CASC8 Gene

Genes around CASC8 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CASC8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CASC8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CASC8 Gene

Proteins for CASC8 Gene

Post-translational modifications for CASC8 Gene

No Post-translational modifications

No data available for DME Specific Peptides for CASC8 Gene

Domains & Families for CASC8 Gene

Gene Families for CASC8 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CASC8: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CASC8 Gene

Function for CASC8 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CASC8 Gene

Localization for CASC8 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CASC8 Gene

Pathways & Interactions for CASC8 Gene

SuperPathways for CASC8 Gene

No Data Available

Interacting Proteins for CASC8 Gene

Gene Ontology (GO) - Biological Process for CASC8 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CASC8 Gene

Drugs & Compounds for CASC8 Gene

No Compound Related Data Available

Transcripts for CASC8 Gene

mRNA/cDNA for CASC8 Gene

(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CASC8 Gene

No ASD Table

Relevant External Links for CASC8 Gene

GeneLoc Exon Structure for
CASC8
ECgene alternative splicing isoforms for
CASC8

Expression for CASC8 Gene

mRNA expression in normal human tissues for CASC8 Gene

mRNA differential expression in normal tissues according to GTEx for CASC8 Gene

This gene is overexpressed in Minor Salivary Gland (x7.6), Colon - Transverse (x5.0), and Esophagus - Mucosa (x4.1).
genes like me logo Genes that share expression patterns with CASC8: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CASC8 Gene

Orthologs for CASC8 Gene

Evolution for CASC8 Gene

ENSEMBL:
Gene Tree for CASC8 (if available)
TreeFam:
Gene Tree for CASC8 (if available)

No data available for Orthologs for CASC8 Gene

Paralogs for CASC8 Gene

No data available for Paralogs for CASC8 Gene

Variants for CASC8 Gene

Sequence variations from dbSNP and Humsavar for CASC8 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs2060776 -- 127,407,872(+) accaa(G/T)caaac intron-variant
rs2121630 -- 127,465,915(-) GAATG(A/C)ACCAG intron-variant
rs2166689 -- 127,466,070(-) TTGTT(A/C)TTATG intron-variant
rs2290033 -- 127,480,829(+) CACTT(C/G)CAGGC nc-transcript-variant
rs7830306 -- 127,458,740(+) CCACC(A/G)AAAAA intron-variant

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for CASC8 Gene

Disorders for CASC8 Gene

Relevant External Links for CASC8

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CASC8

No disorders were found for CASC8 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CASC8 Gene

Publications for CASC8 Gene

  1. Long-range interaction and correlation between MYC enhancer and oncogenic long noncoding RNA CARLo-5. (PMID: 24594601) Kim T. … Croce C.M. (Proc. Natl. Acad. Sci. U.S.A. 2014) 2 3 67
  2. Genetic variant in 8q24 is associated with prognosis for gastric cancer in a Chinese population. (PMID: 25302443) Ma G. … Chen J. (J. Gastroenterol. Hepatol. 2015) 3
  3. Correlation Between CASC8, SMAD7 Polymorphisms and the Susceptibility to Colorectal Cancer: An Updated Meta-Analysis Based on GWAS Results. (PMID: 26579801) Yao K. … Hu J. (Medicine (Baltimore) 2015) 3
  4. Genetic variation in prostate-specific antigen-detected prostate cancer and the effect of control selection on genetic association studies. (PMID: 24753544) Knipe D.W. … Martin R.M. (Cancer Epidemiol. Biomarkers Prev. 2014) 3
  5. Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility. (PMID: 19767754) Gudmundsson J. … Stefansson K. (Nat. Genet. 2009) 3

Products for CASC8 Gene

Sources for CASC8 Gene

Content