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Aliases for CASC18 Gene

Subcategory (RNA class) for CASC18 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for CASC18 Gene

  • Cancer Susceptibility 18 (Non-Protein Coding) 2 3 5
  • Cancer Susceptibility Candidate 18 (Non-Protein Coding) 2

External Ids for CASC18 Gene

Previous GeneCards Identifiers for CASC18 Gene

  • GC12P106099

Summaries for CASC18 Gene

GeneCards Summary for CASC18 Gene

CASC18 (Cancer Susceptibility 18 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for CASC18 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CASC18 Gene

Genomics for CASC18 Gene

GeneHancer (GH) Regulatory Elements for CASC18 Gene

Promoters and enhancers for CASC18 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12I105409 Enhancer 1.2 Ensembl ENCODE dbSUPER 6.8 -294.2 -294174 2 NFIB ZNF529 KLF17 MZF1 FEZF1 ZNF335 ZNF302 KLF7 ZNF214 YY2 APPL2 CASC18 LOC105369955 GC12M105372 LOC105369957
GH12I105382 Enhancer 0.9 Ensembl ENCODE 4.3 -321.0 -321043 1.3 CTCF PKNOX1 RB1 SIN3A ZNF384 RAD21 ZNF335 DIDO1 ZNF143 SMC3 C12orf75 APPL2 CASC18 GC12M105372 LOC105369957 LOC105369955
GH12I105368 Enhancer 0.2 ENCODE 5.2 -335.9 -335935 0.2 CASC18 LOC105369957 KCCAT198 C12orf75
GH12I105369 Enhancer 0.2 ENCODE 5.2 -335.0 -335005 0.2 C12orf75 CASC18 LOC105369957 KCCAT198
GH12I105705 Enhancer 1.2 Ensembl ENCODE dbSUPER 0.8 +2.2 2224 2.5 INSM2 KLF17 FEZF1 ZNF2 RAD21 ZEB1 ZNF335 ZNF213 ZNF366 ZSCAN5C LOC105369959 CASC18
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around CASC18 on UCSC Golden Path with GeneCards custom track

Genomic Locations for CASC18 Gene

Genomic Locations for CASC18 Gene
chr12:105,704,203-105,744,063
(GRCh38/hg38)
Size:
39,861 bases
Orientation:
Plus strand
chr12:106,097,981-106,137,840
(GRCh37/hg19)

Genomic View for CASC18 Gene

Genes around CASC18 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CASC18 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CASC18 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CASC18 Gene

Proteins for CASC18 Gene

Post-translational modifications for CASC18 Gene

No Post-translational modifications

No data available for DME Specific Peptides for CASC18 Gene

Domains & Families for CASC18 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CASC18 Gene

Function for CASC18 Gene

Phenotypes From GWAS Catalog for CASC18 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CASC18 Gene

Localization for CASC18 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CASC18 Gene

Pathways & Interactions for CASC18 Gene

SuperPathways for CASC18 Gene

No Data Available

Interacting Proteins for CASC18 Gene

Gene Ontology (GO) - Biological Process for CASC18 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CASC18 Gene

Drugs & Compounds for CASC18 Gene

No Compound Related Data Available

Transcripts for CASC18 Gene

mRNA/cDNA for CASC18 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CASC18 Gene

No ASD Table

Relevant External Links for CASC18 Gene

GeneLoc Exon Structure for
CASC18
ECgene alternative splicing isoforms for
CASC18

Expression for CASC18 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CASC18 Gene

mRNA differential expression in normal tissues according to GTEx for CASC18 Gene

This gene is overexpressed in Artery - Aorta (x7.5), Artery - Coronary (x4.4), and Artery - Tibial (x4.2).

NURSA nuclear receptor signaling pathways regulating expression of CASC18 Gene:

CASC18
genes like me logo Genes that share expression patterns with CASC18: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CASC18 Gene

Orthologs for CASC18 Gene

Evolution for CASC18 Gene

ENSEMBL:
Gene Tree for CASC18 (if available)
TreeFam:
Gene Tree for CASC18 (if available)

No data available for Orthologs for CASC18 Gene

Paralogs for CASC18 Gene

No data available for Paralogs for CASC18 Gene

Variants for CASC18 Gene

Sequence variations from dbSNP and Humsavar for CASC18 Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs1000008277 -- 105,729,110(+) T/G intron_variant
rs1000171495 -- 105,726,252(+) G/A intron_variant
rs1000196504 -- 105,716,608(+) G/A intron_variant
rs1000229034 -- 105,716,416(+) G/T intron_variant
rs1000357920 -- 105,735,662(+) C/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for CASC18 Gene

Variant ID Type Subtype PubMed ID
dgv1551n100 CNV gain 25217958
nsv1039068 CNV gain 25217958
nsv476086 CNV novel sequence insertion 20440878

Additional Variant Information for CASC18 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CASC18

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CASC18 Gene

Disorders for CASC18 Gene

Additional Disease Information for CASC18

No disorders were found for CASC18 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CASC18 Gene

Publications for CASC18 Gene

  1. Introduction of novel splice variants for CASC18 gene and its relation to the neural differentiation. (PMID: 27956168) Mehravar M … Soltani BM (Gene 2017) 3 58
  2. APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study. (PMID: 23419831) Ramanan VK … Alzheimer’s Disease Neuroimaging Initiative (Molecular psychiatry 2014) 3 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58

Products for CASC18 Gene

Sources for CASC18 Gene

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