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Aliases for CASC15 Gene

Subcategory (RNA class) for CASC15 Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for CASC15 Gene

  • Cancer Susceptibility 15 (Non-Protein Coding) 2 3 5
  • Cancer Susceptibility Candidate 15 (Non-Protein Coding) 2 3
  • Long Intergenic Non-Protein Coding RNA 340 2 3
  • Lnc-SOX4-1 3
  • LINC00340 3

External Ids for CASC15 Gene

Previous HGNC Symbols for CASC15 Gene

  • LINC00340

Summaries for CASC15 Gene

GeneCards Summary for CASC15 Gene

CASC15 (Cancer Susceptibility 15 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with CASC15 include Refractive Error and Neuroblastoma, Susceptibility.

Additional gene information for CASC15 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CASC15 Gene

Genomics for CASC15 Gene

Regulatory Elements for CASC15 Gene

Enhancers for CASC15 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06H022042 0.9 Ensembl ENCODE dbSUPER 20.8 +378.5 378456 1 IKZF1 NR2F2 CASC15 RN7SKP240 GC06P021990
GH06H022044 0.9 ENCODE dbSUPER 18 +380.7 380679 1 NR2F1 ZSCAN4 IRF5 TRIM22 BMI1 NBN MLLT1 ATF7 RUNX3 IKZF2 CASC15 RN7SKP240 GC06P021990
GH06H022041 0.9 Ensembl ENCODE dbSUPER 7.8 +377.2 377181 0 EMSY MAFK CASC15 RN7SKP240 GC06P021990
GH06H021925 1 Ensembl ENCODE 4.7 +261.8 261840 2 KLF1 ATF1 ZBTB21 ETV1 JUN ZNF175 CBX5 RBAK ZNF584 ATF7 CASC15 GC06P021926 GC06M021864
GH06H021873 1 Ensembl ENCODE dbSUPER 4.6 +209.1 209084 0 JUND POLR2A FOS CASC15 GC06P021860 GC06M021864
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CASC15 on UCSC Golden Path with GeneCards custom track

Genomic Location for CASC15 Gene

21,664,772 bp from pter
22,368,328 bp from pter
703,557 bases
Plus strand

Genomic View for CASC15 Gene

Genes around CASC15 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CASC15 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CASC15 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CASC15 Gene

Proteins for CASC15 Gene

Post-translational modifications for CASC15 Gene

No Post-translational modifications

No data available for DME Specific Peptides for CASC15 Gene

Domains & Families for CASC15 Gene

Gene Families for CASC15 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CASC15: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CASC15 Gene

Function for CASC15 Gene

Phenotypes From GWAS Catalog for CASC15 Gene

Phenotypes for CASC15 Gene

GenomeRNAi human phenotypes for CASC15:
genes like me logo Genes that share phenotypes with CASC15: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for CASC15
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CASC15 Gene

Localization for CASC15 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CASC15 Gene

Pathways & Interactions for CASC15 Gene

SuperPathways for CASC15 Gene

No Data Available

Interacting Proteins for CASC15 Gene

Gene Ontology (GO) - Biological Process for CASC15 Gene


No data available for Pathways by source and SIGNOR curated interactions for CASC15 Gene

Drugs & Compounds for CASC15 Gene

No Compound Related Data Available

Transcripts for CASC15 Gene

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for CASC15
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for CASC15 Gene

No ASD Table

Relevant External Links for CASC15 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CASC15 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CASC15 Gene

NURSA nuclear receptor signaling pathways regulating expression of CASC15 Gene:

genes like me logo Genes that share expression patterns with CASC15: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CASC15 Gene

Orthologs for CASC15 Gene

Evolution for CASC15 Gene

Gene Tree for CASC15 (if available)
Gene Tree for CASC15 (if available)

No data available for Orthologs for CASC15 Gene

Paralogs for CASC15 Gene

No data available for Paralogs for CASC15 Gene

Variants for CASC15 Gene

Sequence variations from dbSNP and Humsavar for CASC15 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1000000519 -- 22,075,924(+) TACAT(C/T)ATTAT intron-variant
rs1000006290 -- 22,188,712(+) GAAAA(A/C)AAAAG intron-variant
rs1000006831 -- 21,666,421(+) GAAAC(C/G)TGCCG upstream-variant-2KB
rs1000008951 -- 22,158,589(+) TGACA(A/G)GTGAC intron-variant
rs1000012386 -- 21,865,170(+) TTTCA(C/T)CATAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CASC15 Gene

Variant ID Type Subtype PubMed ID
dgv1002n67 CNV loss 20364138
dgv10319n54 CNV loss 21841781
dgv10320n54 CNV loss 21841781
dgv10321n54 CNV loss 21841781
dgv10322n54 CNV loss 21841781
dgv10323n54 CNV loss 21841781
dgv10324n54 CNV loss 21841781
dgv1078e199 CNV deletion 23128226
dgv1170e214 CNV loss 21293372
dgv1717e212 CNV loss 25503493
dgv1718e212 CNV loss 25503493
dgv3285n106 CNV deletion 24896259
dgv374n21 CNV loss 19592680
esv24725 CNV loss 19812545
esv25369 CNV loss 19812545
esv2621401 CNV deletion 19546169
esv2659390 CNV deletion 23128226
esv2660578 CNV deletion 23128226
esv2667198 CNV deletion 23128226
esv2670770 CNV deletion 23128226
esv2675345 CNV deletion 23128226
esv2678070 CNV deletion 23128226
esv2678811 CNV deletion 23128226
esv27155 CNV loss 19812545
esv2731677 CNV deletion 23290073
esv2731678 CNV deletion 23290073
esv2731679 CNV deletion 23290073
esv2731680 CNV deletion 23290073
esv2763540 CNV loss 21179565
esv3303671 CNV mobile element insertion 20981092
esv3308781 CNV mobile element insertion 20981092
esv3322146 CNV insertion 20981092
esv3336232 CNV insertion 20981092
esv3339910 CNV insertion 20981092
esv3376599 CNV insertion 20981092
esv3419255 CNV insertion 20981092
esv3431161 CNV insertion 20981092
esv3451137 CNV insertion 20981092
esv3567393 CNV deletion 23714750
esv3567396 CNV deletion 23714750
esv3570795 CNV loss 25503493
esv3570797 CNV loss 25503493
esv3570799 CNV loss 25503493
esv3570800 CNV loss 25503493
esv3570802 CNV loss 25503493
esv3570804 CNV loss 25503493
esv3576104 CNV gain 25503493
esv3608312 CNV loss 21293372
esv3608313 CNV loss 21293372
esv3608314 CNV loss 21293372
esv3608315 CNV loss 21293372
esv3608317 CNV gain 21293372
esv3608320 CNV loss 21293372
esv3608323 CNV loss 21293372
esv3608324 CNV loss 21293372
esv3608325 CNV loss 21293372
esv3608328 CNV loss 21293372
esv3608330 CNV loss 21293372
esv3608331 CNV gain 21293372
esv3890797 CNV loss 25118596
esv3890798 CNV loss 25118596
nsv1025837 CNV loss 25217958
nsv1073194 CNV deletion 25765185
nsv1124044 CNV deletion 24896259
nsv1129268 CNV deletion 24896259
nsv1161343 CNV deletion 26073780
nsv348606 CNV deletion 16902084
nsv348739 CNV deletion 16902084
nsv349514 CNV deletion 16902084
nsv349883 CNV deletion 16902084
nsv437478 CNV loss 16327808
nsv475311 CNV novel sequence insertion 20440878
nsv499608 CNV loss 21111241
nsv510019 OTHER sequence alteration 20534489
nsv511855 CNV loss 21212237
nsv516009 CNV loss 19592680
nsv516909 CNV loss 19592680
nsv5223 CNV deletion 18451855
nsv5224 CNV insertion 18451855
nsv525875 CNV loss 19592680
nsv601097 CNV loss 21841781
nsv601104 CNV loss 21841781
nsv818402 CNV loss 17921354
nsv819249 CNV loss 19587683
nsv823444 CNV loss 20364138
nsv823445 CNV loss 20364138
nsv823450 CNV loss 20364138
nsv830602 CNV gain 17160897

Relevant External Links for CASC15 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CASC15 Gene

Disorders for CASC15 Gene

MalaCards: The human disease database

(2) MalaCards diseases for CASC15 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
refractive error
  • refractive errors
neuroblastoma, susceptibility
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for CASC15

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with CASC15: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CASC15 Gene

Publications for CASC15 Gene

  1. The lncRNA CASC15 regulates SOX4 expression in RUNX1-rearranged acute leukemia. (PMID: 28724437) Fernando TR … Rao DS (Molecular cancer 2017) 2 3 60
  2. CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus. (PMID: 26100672) Russell MR … Cole KA (Cancer research 2015) 2 3 60
  3. The CASC15 Long Intergenic Noncoding RNA Locus Is Involved in Melanoma Progression and Phenotype Switching. (PMID: 26016895) Lessard L … Hoon DSB (The Journal of investigative dermatology 2015) 2 3 60
  4. Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium. (PMID: 25367360) Li Q … CREAM Consortium (Human genetics 2015) 3 60
  5. Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma. (PMID: 22941191) Diskin SJ … Maris JM (Nature genetics 2012) 3 60

Products for CASC15 Gene

Sources for CASC15 Gene

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