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Aliases for CASC15 Gene

Subcategory (RNA class) for CASC15 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for CASC15 Gene

  • Cancer Susceptibility Candidate 15 (Non-Protein Coding) 2 3 5
  • Long Intergenic Non-Protein Coding RNA 340 2 3
  • LINC00340 3

External Ids for CASC15 Gene

Previous HGNC Symbols for CASC15 Gene

  • LINC00340

Summaries for CASC15 Gene

GeneCards Summary for CASC15 Gene

CASC15 (Cancer Susceptibility Candidate 15 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with CASC15 include Astigmatism and Refractive Error.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CASC15 Gene

Genomics for CASC15 Gene

Regulatory Elements for CASC15 Gene

Enhancers for CASC15 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CASC15 on UCSC Golden Path with GeneCards custom track

Promoters for CASC15 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CASC15 on UCSC Golden Path with GeneCards custom track

Genomic Location for CASC15 Gene

Chromosome:
6
Start:
21,664,772 bp from pter
End:
22,214,505 bp from pter
Size:
549,734 bases
Orientation:
Plus strand

Genomic View for CASC15 Gene

Genes around CASC15 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CASC15 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CASC15 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CASC15 Gene

Proteins for CASC15 Gene

Post-translational modifications for CASC15 Gene

No Post-translational modifications

No data available for DME Specific Peptides for CASC15 Gene

Domains & Families for CASC15 Gene

Gene Families for CASC15 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CASC15: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CASC15 Gene

Function for CASC15 Gene

Phenotypes for CASC15 Gene

GenomeRNAi human phenotypes for CASC15:
genes like me logo Genes that share phenotypes with CASC15: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CASC15 Gene

Localization for CASC15 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CASC15 Gene

Pathways & Interactions for CASC15 Gene

SuperPathways for CASC15 Gene

No Data Available

Interacting Proteins for CASC15 Gene

Gene Ontology (GO) - Biological Process for CASC15 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CASC15 Gene

Drugs & Compounds for CASC15 Gene

No Compound Related Data Available

Transcripts for CASC15 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for CASC15 Gene

No ASD Table

Relevant External Links for CASC15 Gene

GeneLoc Exon Structure for
CASC15
ECgene alternative splicing isoforms for
CASC15

Expression for CASC15 Gene

mRNA expression in normal human tissues for CASC15 Gene

genes like me logo Genes that share expression patterns with CASC15: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CASC15 Gene

Orthologs for CASC15 Gene

Evolution for CASC15 Gene

ENSEMBL:
Gene Tree for CASC15 (if available)
TreeFam:
Gene Tree for CASC15 (if available)

No data available for Orthologs for CASC15 Gene

Paralogs for CASC15 Gene

No data available for Paralogs for CASC15 Gene

Variants for CASC15 Gene

Sequence variations from dbSNP and Humsavar for CASC15 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1022466 -- 22,088,025(-) CTACA(A/C)TGAAG intron-variant
rs1023056 -- 21,988,523(+) GCATA(G/T)GTACC intron-variant
rs1023057 -- 21,988,567(+) aagta(C/T)actga intron-variant
rs1034069 -- 21,929,024(-) gacag(A/C)catat intron-variant
rs1034070 -- 21,958,479(-) ggcag(A/G)aagat intron-variant

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for CASC15 Gene

Disorders for CASC15 Gene

MalaCards: The human disease database

(3) MalaCards diseases for CASC15 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
astigmatism
refractive error
  • refractive errors
neuroblastoma, susceptibility
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for CASC15

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CASC15
genes like me logo Genes that share disorders with CASC15: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CASC15 Gene

Publications for CASC15 Gene

  1. The CASC15 Long Intergenic Noncoding RNA Locus Is Involved in Melanoma Progression and Phenotype Switching. (PMID: 26016895) Lessard L. … Hoon D.S. (J. Invest. Dermatol. 2015) 2 3 67
  2. CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus. (PMID: 26100672) Russell M.R. … Cole K.A. (Cancer Res. 2015) 2 3
  3. Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium. (PMID: 25367360) Li Q. … Guggenheim J.A. (Hum. Genet. 2014) 3
  4. Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma. (PMID: 22941191) Diskin S.J. … Maris J.M. (Nat. Genet. 2012) 3
  5. Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function. (PMID: 23284291) Hancock D.B. … London S.J. (PLoS Genet. 2012) 3

Products for CASC15 Gene

Sources for CASC15 Gene

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