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Aliases for CASC11 Gene

Subcategory (RNA class) for CASC11 Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for CASC11 Gene

  • Cancer Susceptibility 11 (Non-Protein Coding) 2 3 5
  • Cancer Susceptibility Candidate 11 (Non-Protein Coding) 2 3
  • Long Intergenic Non-Protein Coding RNA 990 2 3
  • TCONS_00014535 3
  • LINC00990 3
  • CARLo-7 3

External Ids for CASC11 Gene

Previous GeneCards Identifiers for CASC11 Gene

  • GC08M128699

Summaries for CASC11 Gene

GeneCards Summary for CASC11 Gene

CASC11 (Cancer Susceptibility 11 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for CASC11 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CASC11 Gene

Genomics for CASC11 Gene

Regulatory Elements for CASC11 Gene

Enhancers for CASC11 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08H128171 2.1 FANTOM5 Ensembl ENCODE dbSUPER 10.5 -442.4 -442417 9.3 HDGF PKNOX1 FOXA2 ARNT ARID4B SIN3A YBX1 FEZF1 DMAP1 ZBTB7B MIR1208 MIR1207 CASC11 MYC RNU4-25P GC08P128172 GC08P128221
GH08H127758 1.8 FANTOM5 Ensembl ENCODE dbSUPER 11.8 -26.2 -26216 2.8 HDAC1 TBP HDGF PKNOX1 ATF1 NFIB ARNT SIN3A ZBTB40 BRCA1 PVT1 MIR1204 MYC CASC11 TMEM75 MIR1207 RNU4-25P GC08P127744
GH08H127806 1.8 FANTOM5 Ensembl ENCODE dbSUPER 11.4 -76.9 -76883 8.6 HDGF PKNOX1 SIN3A YBX1 BRCA1 ZBTB7B GLIS2 ZNF207 FOS REST MYC SRRM1P1 CASC11 TMEM75 MIR1207 RNU1-106P PVT1 MIR1204 ENSG00000278324
GH08H128181 1.9 FANTOM5 Ensembl ENCODE dbSUPER 10.5 -450.1 -450069 5.1 HDGF FOXA2 ATF1 MLX ZFP64 ARID4B YBX1 DMAP1 ZBTB7B TCF12 MYC MIR1208 MIR1207 CASC11 RNU1-106P TMEM75 RNU4-25P GC08P128172 GC08P128221
GH08H127863 1.8 FANTOM5 Ensembl ENCODE dbSUPER 11 -134.4 -134365 10.2 HDGF PKNOX1 ATF1 SIN3A YBX1 ZBTB7B YY1 ETS1 TCF12 ELK1 SRRM1P1 RNU1-106P PVT1 MIR1204 CASC11 MYC TMEM75 RNU4-25P ENSG00000278324
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CASC11 on UCSC Golden Path with GeneCards custom track

Genomic Locations for CASC11 Gene

Genomic Locations for CASC11 Gene
47,625 bases
Minus strand

Genomic View for CASC11 Gene

Genes around CASC11 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CASC11 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CASC11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CASC11 Gene

Proteins for CASC11 Gene

Post-translational modifications for CASC11 Gene

No Post-translational modifications

No data available for DME Specific Peptides for CASC11 Gene

Domains & Families for CASC11 Gene

Gene Families for CASC11 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CASC11: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CASC11 Gene

Function for CASC11 Gene

Phenotypes From GWAS Catalog for CASC11 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CASC11 Gene

Localization for CASC11 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CASC11 Gene

Pathways & Interactions for CASC11 Gene

SuperPathways for CASC11 Gene

No Data Available

Interacting Proteins for CASC11 Gene

Gene Ontology (GO) - Biological Process for CASC11 Gene


No data available for Pathways by source and SIGNOR curated interactions for CASC11 Gene

Drugs & Compounds for CASC11 Gene

No Compound Related Data Available

Transcripts for CASC11 Gene

mRNA/cDNA for CASC11 Gene

(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CASC11 Gene

No ASD Table

Relevant External Links for CASC11 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CASC11 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CASC11 Gene

NURSA nuclear receptor signaling pathways regulating expression of CASC11 Gene:

genes like me logo Genes that share expression patterns with CASC11: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CASC11 Gene

Orthologs for CASC11 Gene

Evolution for CASC11 Gene

Gene Tree for CASC11 (if available)
Gene Tree for CASC11 (if available)

No data available for Orthologs for CASC11 Gene

Paralogs for CASC11 Gene

No data available for Paralogs for CASC11 Gene

Variants for CASC11 Gene

Sequence variations from dbSNP and Humsavar for CASC11 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1000179953 -- 127,727,991(+) AGGAC(A/T)TCAAT intron-variant
rs1000528432 -- 127,721,989(+) GTTCC(A/C)GATTC intron-variant
rs1000582000 -- 127,734,066(+) CACCT(A/G)ACCCC upstream-variant-2KB
rs1000586224 -- 127,715,954(+) GTAAT(A/C/G)CCAGC nc-transcript-variant
rs1000777844 -- 127,734,079(+) CCCTC(G/T)TTGAC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for CASC11 Gene

Variant ID Type Subtype PubMed ID
nsv831458 CNV loss 17160897
nsv7419 OTHER inversion 18451855
nsv516713 CNV gain+loss 19592680
nsv499795 OTHER inversion 21111241
esv3618780 CNV loss 21293372
esv3618779 CNV loss 21293372
esv3544187 CNV deletion 23714750
esv2752208 CNV gain 17911159
esv2675213 CNV deletion 23128226
esv2658660 CNV deletion 23128226

Relevant External Links for CASC11 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CASC11 Gene

Disorders for CASC11 Gene

Relevant External Links for CASC11

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CASC11 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CASC11 Gene

Publications for CASC11 Gene

  1. Identification of long noncoding RNA expression profile in oxaliplatin-resistant hepatocellular carcinoma cells. (PMID: 27729273) Yin X … Ren ZG (Gene 2017) 2 3 60
  2. Long-range interaction and correlation between MYC enhancer and oncogenic long noncoding RNA CARLo-5. (PMID: 24594601) Kim T … Croce CM (Proceedings of the National Academy of Sciences of the United States of America 2014) 2 3 60
  3. Long non-coding RNA CASC11 interacts with hnRNP-K and activates the WNT/β-catenin pathway to promote growth and metastasis in colorectal cancer. (PMID: 27012187) Zhang Z … Li X (Cancer letters 2016) 3 60
  4. Sequence variant on 8q24 confers susceptibility to urinary bladder cancer. (PMID: 18794855) Kiemeney LA … Stefansson K (Nature genetics 2008) 3 60

Products for CASC11 Gene

Sources for CASC11 Gene

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