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Aliases for CASC10 Gene

Aliases for CASC10 Gene

  • Cancer Susceptibility Candidate 10 2 3
  • Cancer Susceptibility Candidate Gene 10 Protein 3 4
  • C10orf114 3 4
  • Chromosome 10 Open Reading Frame 114 2
  • Protein CASC10 3
  • BA418C1.3 3

External Ids for CASC10 Gene

Previous Symbols for CASC10 Gene

  • C10orf114

Summaries for CASC10 Gene

GeneCards Summary for CASC10 Gene

CASC10 (Cancer Susceptibility Candidate 10) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CASC10 Gene

Genomics for CASC10 Gene

Genomic Location for CASC10 Gene

Start:
21,490,473 bp from pter
End:
21,497,284 bp from pter
Size:
6,812 bases
Orientation:
Minus strand

Genomic View for CASC10 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CASC10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CASC10 Gene

No data available for Regulatory Elements for CASC10 Gene

Proteins for CASC10 Gene

  • Protein details for CASC10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T4H9-CSC10_HUMAN
    Recommended name:
    Protein CASC10
    Protein Accession:
    Q5T4H9
    Secondary Accessions:
    • A1L4M3

    Protein attributes for CASC10 Gene

    Size:
    136 amino acids
    Molecular mass:
    14851 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CASC10 Gene

Proteomics data for CASC10 Gene at MOPED

Post-translational modifications for CASC10 Gene

No Post-translational modifications

Other Protein References for CASC10 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CASC10 Gene

Domains for CASC10 Gene

Protein Domains for CASC10 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CASC10: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CASC10 Gene

Function for CASC10 Gene

miRNA for CASC10 Gene

miRTarBase miRNAs that target CASC10

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for CASC10 Gene

Localization for CASC10 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CASC10 Gene

Pathways for CASC10 Gene

SuperPathways for CASC10 Gene

No Data Available

Interacting Proteins for CASC10 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000366317%0d%0a9606.ENSP00000385269%0d%0a
Selected Interacting proteins: ENSP00000366317 for CASC10 Gene via STRING

Symbol External ID(s) Details
ELAVL1

Gene Ontology (GO) - Biological Process for CASC10 Gene

None

No data available for Pathways by source for CASC10 Gene

Transcripts for CASC10 Gene

mRNA/cDNA for CASC10 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for CASC10 Gene

No ASD Table

Relevant External Links for CASC10 Gene

GeneLoc Exon Structure for
CASC10
ECgene alternative splicing isoforms for
CASC10

Expression for CASC10 Gene

mRNA expression in normal human tissues for CASC10 Gene

mRNA differential expression in normal tissues according to GTEx for CASC10 Gene

This gene is overexpressed in Liver (4.6).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for CASC10 Gene

genes like me logo Genes that share expressions with CASC10: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for CASC10 Gene

Orthologs for CASC10 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for CASC10 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CASC10 35
  • 99.51 (n)
  • 99.26 (a)
CASC10 36
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia A930004D18Rik 16
Species with no ortholog for CASC10:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CASC10 Gene

ENSEMBL:
Gene Tree for CASC10 (if available)
TreeFam:
Gene Tree for CASC10 (if available)

Paralogs for CASC10 Gene

No data available for Paralogs for CASC10 Gene

Variants for CASC10 Gene

Sequence variations from dbSNP and Humsavar for CASC10 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs1113549 -- 21,491,029(-) GCTAT(G/T)TAGAT intron-variant
rs1114070 -- 21,491,063(-) TTTTA(A/G)ATTTG intron-variant
rs5011832 -- 21,493,913(+) TAAGT(C/T)TGGTG intron-variant
rs7076249 -- 21,491,741(+) CCTTG(A/G)TAACT intron-variant
rs11012724 - 21,495,793(+) GAACC(C/G)GGTGG missense, reference, nc-transcript-variant

Relevant External Links for CASC10 Gene

HapMap Linkage Disequilibrium report
CASC10

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CASC10 Gene

Disorders for CASC10 Gene

No disorders were found for CASC10 Gene.

No data available for UniProtKB/Swiss-Prot for CASC10 Gene

Publications for CASC10 Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4
  2. Common variation at 10p12.31 near MLLT10 influences meningioma risk. (PMID: 21804547) Dobbins S.E. … Houlston R.S. (Nat. Genet. 2011) 2 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3

Products for CASC10 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate CASC10
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for CASC10
    • Block miRNA regulation of CASC10 using miScript Target Protectors

    Sources for CASC10 Gene

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