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Aliases for CARM1 Gene

Aliases for CARM1 Gene

  • Coactivator Associated Arginine Methyltransferase 1 2 3 5
  • Protein Arginine N-Methyltransferase 4 3 4
  • PRMT4 3 4
  • Coactivator-Associated Arginine Methyltransferase 1 4
  • Histone-Arginine Methyltransferase CARM1 3
  • EC 2.1.1.319 4
  • EC 2.1.1 58

External Ids for CARM1 Gene

Previous GeneCards Identifiers for CARM1 Gene

  • GC19P011113
  • GC19P010827
  • GC19P010843
  • GC19P010982
  • GC19P010560

Summaries for CARM1 Gene

Entrez Gene Summary for CARM1 Gene

  • This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin-associated proteins and is involved in regulation of gene expression. The enzyme may act in association with other proteins or within multi-protein complexes and may play a role in cell type-specific functions and cell lineage specification. A related pseudogene is located on chromosome 9. [provided by RefSeq, Aug 2013]

GeneCards Summary for CARM1 Gene

CARM1 (Coactivator Associated Arginine Methyltransferase 1) is a Protein Coding gene. Among its related pathways are Cell cycle Role of SCF complex in cell cycle regulation and Metabolism. GO annotations related to this gene include protein homodimerization activity and transcription regulatory region DNA binding. An important paralog of this gene is PRMT2.

UniProtKB/Swiss-Prot for CARM1 Gene

  • Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at Arg-17 (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stimulation, acts together with EP300/P300 as a coactivator for NF-kappa-B. Acts as coactivator for PPARG, promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA alternative splicing by methylation of splicing factors. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at Arg-2142, which may loosen its interaction with NCOA2/GRIP1, and at Arg-580 and Arg-604 in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1, ELAVL1 and ELAV4, which may affect their mRNA-stabilizing properties and the half-life of their target mRNAs.

Additional gene information for CARM1 Gene

No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CARM1 Gene

Genomics for CARM1 Gene

Regulatory Elements for CARM1 Gene

Enhancers for CARM1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19H010717 1.7 FANTOM5 ENCODE dbSUPER 11 -152.4 -152358 3 HDGF PKNOX1 FOXA2 ARNT ARID4B SIN3A FEZF1 ZNF2 ZBTB7B YY1 KRI1 EIF3G ILF3 FBXL12 RAVER1 TIMM29 PPAN QTRT1 ZNF627 CNN1
GH19H011373 1.7 FANTOM5 ENCODE dbSUPER 10.9 +504.8 504807 6 HDGF PKNOX1 ARNT ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 ILF3 ZNF136 KRI1 ZNF627 ZNF442 ZNF625 ZNF823 ZNF844 ZNF491 ZNF44
GH19H011150 1.6 Ensembl ENCODE dbSUPER 10.9 +282.3 282310 6 HDGF PKNOX1 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 KRI1 ILF3 TIMM29 ZNF20 ZNF700 ZNF627 ZNF433 ZNF878 ZNF763 ZNF440
GH19H011380 1.4 ENCODE dbSUPER 10.9 +510.9 510853 5 HDGF PKNOX1 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B ILF3 ZNF136 KRI1 TIMM29 ZNF627 ZNF433 ZNF844 ZNF442 ZNF44 ZNF563
GH19H010251 1.2 ENCODE 10.9 -619.4 -619385 2 HDGF PKNOX1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 ZNF143 ZNF207 ILF3 DNMT1 LOC100419831 LOC100128428 ZNF699 ZNF559 ZNF266 QTRT1 KRI1 ZNF177
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CARM1 on UCSC Golden Path with GeneCards custom track

Promoters for CARM1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000107099 387 2201 HDGF ATF1 DMAP1 BRCA1 TCF12 ZNF121 GLIS2 ZNF143 KLF7 ATF7

Genomic Location for CARM1 Gene

Chromosome:
19
Start:
10,871,513 bp from pter
End:
10,923,070 bp from pter
Size:
51,558 bases
Orientation:
Plus strand

Genomic View for CARM1 Gene

Genes around CARM1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CARM1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CARM1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CARM1 Gene

Proteins for CARM1 Gene

  • Protein details for CARM1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86X55-CARM1_HUMAN
    Recommended name:
    Histone-arginine methyltransferase CARM1
    Protein Accession:
    Q86X55
    Secondary Accessions:
    • A6NN38

    Protein attributes for CARM1 Gene

    Size:
    608 amino acids
    Molecular mass:
    65854 Da
    Quaternary structure:
    • Homodimer (Probable). Interacts with the C-terminus of NCOA2/GRIP1, NCO3/ACTR and NCOA1/SRC1. Part of a complex consisting of CARM1, EP300/P300 and NCOA2/GRIP1. Interacts with FLII, TP53, myogenic factor MEF2, EP300/P300, TRIM24, CREBBP and CTNNB1. Identified in a complex containing CARM1, TRIM24 and NCOA2/GRIP1. Interacts with NCOA3/SRC3. Interacts with SNRPC (By similarity). Interacts with NR1H4. Interacts with RELA. Interacts with HTLV-1 Tax-1.

    Three dimensional structures from OCA and Proteopedia for CARM1 Gene

    Alternative splice isoforms for CARM1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CARM1 Gene

Selected DME Specific Peptides for CARM1 Gene

Q86X55:
  • DKIVLDVG
  • VLDVGCG
  • GCGSGIL

Post-translational modifications for CARM1 Gene

  • Auto-methylated on Arg-550. Methylation enhances transcription coactivator activity. Methylation is required for its role in the regulation of pre-mRNA alternative splicing (By similarity).
  • Phosphorylation at Ser-216 interferes with S-adenosyl-L-methionine binding and strongly reduces methyltransferase activity (By similarity). Phosphorylation at Ser-216 is strongly increased during mitosis, and decreases rapidly to a very low, basal level after entry into the G1 phase of the cell cycle. Phosphorylation at Ser-216 may promote location in the cytosol.
  • Ubiquitination at Lys227 and Lys470
  • Modification sites at PhosphoSitePlus

Antibody Products

  • Cell Signaling Technology (CST) Antibodies for CARM1 (CARM1)

Domains & Families for CARM1 Gene

Gene Families for CARM1 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Cancer-related genes
  • Enzymes
  • Predicted intracellular proteins
  • Predicted secreted proteins

Protein Domains for CARM1 Gene

Suggested Antigen Peptide Sequences for CARM1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q86X55

UniProtKB/Swiss-Prot:

CARM1_HUMAN :
  • Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
Family:
  • Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
genes like me logo Genes that share domains with CARM1: view

Function for CARM1 Gene

Molecular function for CARM1 Gene

UniProtKB/Swiss-Prot CatalyticActivity:
2 S-adenosyl-L-methionine + [protein]-L-arginine = 2 S-adenosyl-L-homocysteine + [protein]-N(omega),N(omega)-dimethyl-L-arginine.
UniProtKB/Swiss-Prot EnzymeRegulation:
Methylation of H3R17 (H3R17me) by CARM1 is stimulated by preacetylation of H3 Lys-18 (H3K18ac) H3 Lys-23 (H3K23ac) by EP300 and blocked by citrullination of H3 Arg-17 (H3R17ci) by PADI4.
UniProtKB/Swiss-Prot Function:
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at Arg-17 (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stimulation, acts together with EP300/P300 as a coactivator for NF-kappa-B. Acts as coactivator for PPARG, promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA alternative splicing by methylation of splicing factors. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at Arg-2142, which may loosen its interaction with NCOA2/GRIP1, and at Arg-580 and Arg-604 in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1, ELAVL1 and ELAV4, which may affect their mRNA-stabilizing properties and the half-life of their target mRNAs.

Enzyme Numbers (IUBMB) for CARM1 Gene

Phenotypes From GWAS Catalog for CARM1 Gene

Gene Ontology (GO) - Molecular Function for CARM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001105 RNA polymerase II transcription coactivator activity IEA --
GO:0003713 transcription coactivator activity ISS --
GO:0005515 protein binding IPI 20111005
GO:0008013 beta-catenin binding TAS 16344550
GO:0008168 methyltransferase activity IEA --
genes like me logo Genes that share ontologies with CARM1: view
genes like me logo Genes that share phenotypes with CARM1: view

Animal Models for CARM1 Gene

MGI Knock Outs for CARM1:

Animal Model Products

  • Taconic Biosciences Mouse Models for CARM1

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for CARM1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CARM1 Gene

Localization for CARM1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CARM1 Gene

Nucleus. Cytoplasm. Note=Mainly nuclear during the G1, S and G2 phases of the cell cycle. Cytoplasmic during mitosis, after breakup of the nuclear membrane.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CARM1 gene
Compartment Confidence
nucleus 5
cytosol 5
peroxisome 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for CARM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA,IEA 15221992
GO:0005654 nucleoplasm TAS --
GO:0005737 cytoplasm IEA,IDA 15221992
GO:0005829 cytosol ISS,IBA --
GO:0043234 protein complex IEA --
genes like me logo Genes that share ontologies with CARM1: view

Pathways & Interactions for CARM1 Gene

genes like me logo Genes that share pathways with CARM1: view

SIGNOR curated interactions for CARM1 Gene

Activates:

Gene Ontology (GO) - Biological Process for CARM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003420 regulation of growth plate cartilage chondrocyte proliferation IEA --
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA,ISS --
GO:0006479 protein methylation IEA --
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest TAS --
genes like me logo Genes that share ontologies with CARM1: view

Drugs & Compounds for CARM1 Gene

(8) Drugs for CARM1 Gene - From: DGIdb, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
s-adenosylhomocysteine Experimental Pharma 0
BMS PYRAZOLE INHIBITOR 7F Pharma 0
COMPOUND 17F [PMID:19632837] Pharma 0

(3) Additional Compounds for CARM1 Gene - From: Novoseek and HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
s-adenosylmethionine
  • (3S)-5'-[(3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine
  • 2-S-Adenosyl-L-methionine
  • 5'-Deoxyadenosine-5'-L-methionine disulfate ditosylate
  • 5'-Deoxyadenosine-5'-L-methionine disulphate ditosylate
  • Active methionine
29908-03-0
genes like me logo Genes that share compounds with CARM1: view

Transcripts for CARM1 Gene

Unigene Clusters for CARM1 Gene

Coactivator-associated arginine methyltransferase 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for CARM1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for CARM1 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b · 10c ^ 11a · 11b ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16a ·
SP1: - -
SP2: - - -
SP3: - - -
SP4: - - -
SP5: - - -
SP6: - - - -
SP7:
SP8: - -
SP9: -

ExUns: 16b
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:

Relevant External Links for CARM1 Gene

GeneLoc Exon Structure for
CARM1
ECgene alternative splicing isoforms for
CARM1

Expression for CARM1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CARM1 Gene

mRNA differential expression in normal tissues according to GTEx for CARM1 Gene

This gene is overexpressed in Muscle - Skeletal (x4.1).

Protein differential expression in normal tissues from HIPED for CARM1 Gene

This gene is overexpressed in Breast (10.3) and Uterus (6.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CARM1 Gene



Protein tissue co-expression partners for CARM1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of CARM1 Gene:

CARM1

SOURCE GeneReport for Unigene cluster for CARM1 Gene:

Hs.323213

mRNA Expression by UniProt/SwissProt for CARM1 Gene:

Q86X55-CARM1_HUMAN
Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.

Evidence on tissue expression from TISSUES for CARM1 Gene

  • Nervous system(4.5)
  • Skin(4.2)
  • Muscle(2.9)
genes like me logo Genes that share expression patterns with CARM1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for CARM1 Gene

Orthologs for CARM1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for CARM1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CARM1 34
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CARM1 33 34
  • 93.57 (n)
rat
(Rattus norvegicus)
Mammalia Carm1 33
  • 91.14 (n)
cow
(Bos Taurus)
Mammalia CARM1 33 34
  • 91.05 (n)
mouse
(Mus musculus)
Mammalia Carm1 33 16 34
  • 90.51 (n)
oppossum
(Monodelphis domestica)
Mammalia CARM1 34
  • 90 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CARM1 34
  • 85 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CARM1 34
  • 95 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia carm1 33
  • 77.89 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.9644 33
zebrafish
(Danio rerio)
Actinopterygii carm1 33 34
  • 77.14 (n)
btg1 33
African malaria mosquito
(Anopheles gambiae)
Insecta CARM1_ANOGA 33
  • 64.43 (n)
fruit fly
(Drosophila melanogaster)
Insecta Art4 34 33
  • 60.64 (n)
OneToOne
CG5358 35
  • 59 (a)
CG16840 35
  • 37 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes HMT1 34
  • 33 (a)
OneToMany
thale cress
(Arabidopsis thaliana)
eudicotyledons PRMT4B 33
  • 52.93 (n)
rice
(Oryza sativa)
Liliopsida Os07g0671700 33
  • 53.45 (n)
Os.10778 33
sea squirt
(Ciona savignyi)
Ascidiacea CSA.5717 34
  • 60 (a)
OneToOne
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.2441 33
Species where no ortholog for CARM1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CARM1 Gene

ENSEMBL:
Gene Tree for CARM1 (if available)
TreeFam:
Gene Tree for CARM1 (if available)

Paralogs for CARM1 Gene

Paralogs for CARM1 Gene

(4) SIMAP similar genes for CARM1 Gene using alignment to 7 proteins:

Pseudogenes.org Pseudogenes for CARM1 Gene

genes like me logo Genes that share paralogs with CARM1: view

Variants for CARM1 Gene

Sequence variations from dbSNP and Humsavar for CARM1 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000004367 -- 10,877,923(+) TGCAG(C/T)CTCTA intron-variant
rs1000022008 -- 10,892,978(+) GATCC(A/C/G)CCCGC intron-variant
rs1000077821 -- 10,881,048(+) CTAGT(C/T)CCAGC intron-variant
rs1000105798 -- 10,918,954(+) TGTGT(G/T)AGTCG intron-variant
rs1000235539 -- 10,880,867(+) CATGT(A/G)AAATA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CARM1 Gene

Variant ID Type Subtype PubMed ID
esv3583244 CNV loss 25503493
nsv1144864 CNV deletion 24896259
nsv1160584 CNV deletion 26073780
nsv474981 CNV novel sequence insertion 20440878
nsv833748 CNV loss 17160897
nsv833749 CNV loss 17160897

Variation tolerance for CARM1 Gene

Residual Variation Intolerance Score: 8.39% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.26; 40.51% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CARM1 Gene

Human Gene Mutation Database (HGMD)
CARM1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CARM1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CARM1 Gene

Disorders for CARM1 Gene

Relevant External Links for CARM1

Genetic Association Database (GAD)
CARM1
Human Genome Epidemiology (HuGE) Navigator
CARM1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CARM1

No disorders were found for CARM1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CARM1 Gene

Publications for CARM1 Gene

  1. Biochemical control of CARM1 enzymatic activity by phosphorylation. (PMID: 19843527) Feng Q … O'Malley BW (The Journal of biological chemistry 2009) 3 4 22 60
  2. Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort. (PMID: 19183483) Haiman CA … Press MF (BMC cancer 2009) 3 22 45 60
  3. Coactivator-associated arginine methyltransferase 1 enhances transcriptional activity of the human T-cell lymphotropic virus type 1 long terminal repeat through direct interaction with Tax. (PMID: 17005681) Jeong SJ … Brady JN (Journal of virology 2006) 3 4 22 60
  4. Coactivator-associated arginine methyltransferase-1 enhances nuclear factor-kappaB-mediated gene transcription through methylation of histone H3 at arginine 17. (PMID: 16497732) Miao F … Natarajan R (Molecular endocrinology (Baltimore, Md.) 2006) 3 4 22 60
  5. Regulation of coactivator complex assembly and function by protein arginine methylation and demethylimination. (PMID: 15731352) Lee YH … Stallcup MR (Proceedings of the National Academy of Sciences of the United States of America 2005) 3 4 22 60

Products for CARM1 Gene

Sources for CARM1 Gene

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