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CARKD Gene

protein-coding   GIFtS: 48
GCID: GC13P111267

Carbohydrate Kinase Domain Containing

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Carbohydrate Kinase Domain Containing1 2
Carbohydrate Kinase Domain-Containing Protein2 3
ATP-Dependent NAD(P)HX Dehydratase2 3
LP32982
ATP-Dependent (S)-NAD(P)H-Hydrate Dehydratase2
EC 4.2.1.933

External Ids:    HGNC: 255761   Entrez Gene: 557392   Ensembl: ENSG000002139957   UniProtKB: Q8IW453   

Export aliases for CARKD gene to outside databases

Previous GC identifers: GC13P110067 GC13P091867


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CARKD Gene:
CARKD (carbohydrate kinase domain containing) is a protein-coding gene. Diseases associated with CARKD include tuberculosis, and malaria. GO annotations related to this gene include ATP-dependent NAD(P)H-hydrate dehydratase activity.

UniProtKB/Swiss-Prot: NNRD_HUMAN, Q8IW45
Function: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP.
Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the
repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent
hydration (By similarity)

Gene Wiki entry for CARKD Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000013.11  NC_018924.2  NT_009952.15  
Regulatory elements:
   Regulatory transcription factor binding sites in the CARKD gene promoter:
         Max1   GR   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   C/EBPalpha   GATA-2   PPAR-alpha   S8   Nkx6-1   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCARKD promoter sequence
   Search Chromatin IP Primers for CARKD

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CARKD


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q34   Ensembl cytogenetic band:  13q34   HGNC cytogenetic band: 13q34

CARKD Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CARKD gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13P111267:  view genomic region     (about GC identifiers)

Start:
111,267,807 bp from pter      End:
111,292,343 bp from pter
Size:
24,537 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: NNRD_HUMAN, Q8IW45 (See protein sequence)
Recommended Name: ATP-dependent (S)-NAD(P)H-hydrate dehydratase precursor  
Size: 347 amino acids; 36576 Da
Cofactor: Magnesium (By similarity)
Secondary accessions: B4DXT4 Q5T9X3 Q9H7W1 Q9NVF5
Alternative splicing: 4 isoforms:  Q8IW45-1   Q8IW45-2   Q8IW45-3   Q8IW45-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CARKD: NX_Q8IW45

Explore proteomics data for CARKD at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn240, Asn297
  • Modification sites at PhosphoSitePlus

  • See CARKD Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001229810.1  NP_001229811.1  NP_001229812.1  NP_060680.2  

    ENSEMBL proteins: 
     ENSP00000311984   ENSP00000412789   ENSP00000413191   ENSP00000380375  

    CARKD Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for CARKD

    CARKD Antibody Products:

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    CARKD Assay Products:

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    Cloud-Clone Corp. CLIAs for CARKD


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR000631 YjeF_C_carb_kinase-rel
     IPR026599 NnrD/CARKD

    Graphical View of Domain Structure for InterPro Entry Q8IW45

    ProtoNet protein and cluster: Q8IW45

    1 Blocks protein domain: IPB000631 Protein of unknown function UPF0031

    UniProtKB/Swiss-Prot: NNRD_HUMAN, Q8IW45
    Similarity: Belongs to the NnrD/CARKD family
    Similarity: Contains 1 YjeF C-terminal domain


    CARKD for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NNRD_HUMAN, Q8IW45
    Function: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP.
    Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the
    repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent
    hydration (By similarity)
    Catalytic activity: ATP + (6S)-6-beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide = ADP +
    phosphate + NADH
    Catalytic activity: ATP + (6S)-6-beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate = ADP
    + phosphate + NADPH

         Enzyme Number (IUBMB): EC 4.2.1.931

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005524ATP binding IEA--
    GO:0047453ATP-dependent NAD(P)H-hydrate dehydratase activity IEA--
         
    CARKD for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CARKD
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    2 qRT-PCR Assays for microRNAs that regulate CARKD:
    hsa-miR-633 hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmidCARKD 3' UTR sequence
    Inhib. RNA
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    Browse Sino Biological Human cDNA Clones
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NNRD_HUMAN, Q8IW45: Mitochondrion (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular2
    mitochondrion2
    cytosol1
    endoplasmic reticulum1
    golgi apparatus1
    lysosome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005739mitochondrion IEA--

    CARKD for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CARKD
    Interactions:

        Search GeneGlobe Interaction Network for CARKD

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    Selected Interacting proteins for CARKD (Q8IW453 ENSP000003119844) via UniProtKB, MINT, STRING, and/or I2D (see all 23)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APOA1BPQ8NCW53, ENSP000003572184I2D: score=1 STRING: ENSP00000357218
    POLR2BP308763, ENSP000003127354I2D: score=1 STRING: ENSP00000312735
    DCP1BQ8IZD43I2D: score=5 
    CAMK1DQ8IU853I2D: score=2 
    NTMT1Q9BV863I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    CARKD for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CARKD (NNRD)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CARKD gene (4 alternative transcripts): 
    NM_001242881.1  NM_001242882.1  NM_001242883.1  NM_018210.3  

    Unigene Cluster for CARKD:

    Carbohydrate kinase domain containing
    Hs.408324  [show with all ESTs]
    Unigene Representative Sequence: NM_018210
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000470164(uc001vra.3 uc010tjk.2 uc010tjl.2 uc021rmn.1)
    ENST00000309957(uc010tjj.2 uc001vqz.3 uc001vrb.3 uc001vrc.3)
    ENST00000458711 ENST00000424185 ENST00000397191(uc010tji.2)
    miRNA
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    2 qRT-PCR Assays for microRNAs that regulate CARKD:
    hsa-miR-633 hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmidCARKD 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CARKD
    Clone
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    GenScript: all cDNA clones in your preferred vector: CARKD (NM_018210)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CARKD
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CARKD
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for CARKD
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CARKD
      QuantiTect SYBR Green Assays in human, mouse, rat CARKD
      QuantiFast Probe-based Assays in human, mouse, rat CARKD

    Additional mRNA sequence: 

    AF091088.1 AF151071.1 AK001631.1 AK024260.1 AK093771.1 AK095260.1 AK225129.1 AK296758.1 
    AK298917.1 AK302117.1 BC005150.2 BC006416.1 BC041028.1 NR_040103.1 NR_040104.1 

    Selected DOTS entries (see all 31):

    DT.91854348  DT.418917  DT.100791636  DT.100791645  DT.120787690  DT.100791642  DT.102843366  DT.100791639 
    DT.120787584  DT.120787686  DT.91884566  DT.97781647  DT.120787539  DT.100791641  DT.120787694  DT.92435618 
    DT.100791643  DT.92435624  DT.99937329  DT.120787565  DT.120787638  DT.95374624  DT.100791644  DT.120787543 

    Selected AceView cDNA sequences (see all 461):

    AK095260 AI272911 AW439216 CA424117 AI376420 AA939010 H47626 AA336510 
    Z38476 BQ223094 AA256598 AY203948 CA437650 BQ706137 AA371035 AA010947 
    AL529824 AA632248 AA628769 AW339312 AA235187 AA132774 AI368102 AX748297 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CARKD expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GACATTTTTC
    CARKD Expression
    About this image

    CARKD Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CARKD Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.408324
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CARKD gene from Selected species (see all 26)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Carkd1 , 5 carbohydrate kinase domain containing1, 5 82.06(n)1
    82.48(a)1
      8 (5.73 cM)5
    692251  NM_001190357.11  NP_001177286.11 
     114975065 
    chicken
    (Gallus gallus)
    Aves CARKD1 carbohydrate kinase domain containing 73.14(n)
    76.11(a)
      418755  XM_004938537.1  XP_004938594.1 
    lizard
    (Anolis carolinensis)
    Reptilia CARKD6
    carbohydrate kinase domain containing
    46(a)
    1 ↔ 1
    3(104419789-104449378)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.123052 Xenopus laevis transcribed sequence with weak similarity more 75.72(n)    BX846804.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CF995974.12   -- 71.86(n)    CF995974.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG104241 CG10424 53.93(n)
    48.93(a)
      40085  NM_140833.3  NP_649090.1 
    worm
    (Caenorhabditis elegans)
    Secernentea R107.26
    Protein R107.2 (R107.2) mRNA, complete cds
    37(a)
    1 ↔ 1
    III(9043881-9045940) WBGene00011298
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes (YKL151C)4
    YKL151C1
    Putative protein of unknown function; YKL151C promoter more4
    YKL151C1
    48.83(n)1
    42.61(a)1
      11(165930-164917)4
    8537061, 4  NP_012771.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G191501 AT5G19150 49.23(n)
    47.68(a)
      832035  NM_121920.3  NP_568369.1 
    rice
    (Oryza sativa)
    Liliopsida Os.114232 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 72.68(n)    AK103343.1 


    ENSEMBL Gene Tree for CARKD (if available)
    TreeFam Gene Tree for CARKD (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CARKD gene
    1 SIMAP similar gene for CARKD using alignment to 3 protein entries:     NNRD_HUMAN (see all proteins):
    FLJ10769

    CARKD for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CARKD (see all 747)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1461301541,2
    C--111265899(+) TGGGTC/TGAGTG 4 -- us2k10--------
    rs1113670531,2
    C,F--111265930(+) GTCTTG/ACAAGA 4 -- us2k12Minor allele frequency- A:0.50CSA 4
    rs1850227871,2
    --111266029(+) ATGCAC/TCAATC 6 -- us2k10--------
    rs1899075901,2
    --111266031(+) GCACCA/GATCAG 6 -- us2k10--------
    rs1816114831,2
    --111266032(+) CACCAA/GTCAGT 6 -- us2k10--------
    rs1165416191,2
    C,F--111266169(+) CCCACC/GCCCCC 6 -- us2k11Minor allele frequency- G:0.05WA 118
    rs21480781,2
    C,F,H--111266174(-) GGGGTG/CGGGGG 6 -- us2k16Minor allele frequency- C:0.04NS EA NA 422
    rs1487478421,2
    C--111266248(+) CTCTTC/TATAAT 6 -- us2k10--------
    rs95882071,2
    C,F,A--111266257(+) atgaaT/Actttt 6 -- us2k14Minor allele frequency- A:0.12NA CSA WA 241
    rs1130885651,2
    C,F--111266289(+) GTCTCG/ACTCTG 6 -- us2k11Minor allele frequency- A:0.50CSA 2

    HapMap Linkage Disequilibrium report for CARKD (111267807 - 111292343 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for CARKD:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv901012CNV Loss21882294
    nsv832720CNV Loss17160897
    nsv901013CNV Loss21882294
    nsv456120CNV Loss19166990
    nsv525124CNV Loss19592680
    dgv1791n71CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CARKD
    DNA2.0 Custom Variant and Variant Library Synthesis for CARKD

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    2 diseases for CARKD:    About MalaCards
    tuberculosis    malaria


    CARKD for disorders           About GeneDecksing

    Genetic Association Database (GAD): CARKD
    Human Genome Epidemiology (HuGE) Navigator: CARKD (2 documents)

    Export disorders for CARKD gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CARKD gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with CARKD)
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    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    6. Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. (PubMed id 19159218)2 Chen R.... Zou H. (J. Proteome Res. 2009)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    8. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)2 Dunham A.... Ross M.T. (Nature 2004)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55739 HGNC: 25576 AceView: ING1andFLJ10769 Ensembl:ENSG00000213995 euGenes: HUgn55739
    ECgene: CARKD H-InvDB: CARKD

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CARKD Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CARKD gene:
    Search GeneIP for patents involving CARKD

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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