Aliases for CARD6 Gene
External Ids for CARD6 Gene
This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB. [provided by RefSeq, Jul 2008]
GeneCards Summary for CARD6 Gene
CARD6 (Caspase Recruitment Domain Family, Member 6) is a Protein Coding gene. Among its related pathways are Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways and Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways. An important paralog of this gene is URGCP.
UniProtKB/Swiss-Prot for CARD6 Gene
May be involved in apoptosis