Aliases for CARD18 Gene
External Ids for CARD18 Gene
GeneCards Summary for CARD18 Gene
CARD18 (Caspase Recruitment Domain Family, Member 18) is a Protein Coding gene. Among its related pathways are Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways. GO annotations related to this gene include cysteine-type endopeptidase activity and cysteine-type endopeptidase inhibitor activity. An important paralog of this gene is CARD16.
UniProtKB/Swiss-Prot for CARD18 Gene
Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B.